Zymeworks Inc. (ZYME)Healthcare | Biotechnology | Middletown, United States | NasdaqGS
24.94 USD
-0.94
(-3.632%) ⇩
(July 13, 2026, 4 p.m.
EDT)
After hours: 24.94 |
Hot Take ↕ | July 11, 2026, 4:05 a.m. EDT
The investment case here is fractured by a severe disconnect between the market's optimism and the company's operational reality. While analysts are pushing for a 'strong buy' rating based on the Theravance acquisition, the underlying business is hemorrhaging value. Revenue has collapsed by 91% year-over-year, and the company is burning cash with gross margins in negative territory. This is not a value trap; it is a distressed biotech asset where the market is pricing in a miracle turnaround from the acquisition that hasn't happened yet. The short-term outlook remains murky. The stock is hovering near its 200-day average, showing some resilience, but the statistical forecasting models offer no directional edge, reflecting the uncertainty surrounding the integration of the new assets. The options market confirms this hesitation, with traders placing heavy bets on both a bounce to $30 and a crash to $22.50, rather than committing to a trend. Long-term, the fundamentals are dire. The company is losing money, shrinking its top line, and has no dividend to cushion the blow. The massive premium paid for Theravance has not yet translated into profitable operations, and the balance sheet, while currently liquid, is being drained by R&D and integration costs. Until there is concrete evidence of revenue recovery or a path to profitability, this remains a high-risk speculative vehicle unsuitable for a core portfolio. |
| Model | MAE |
|---|---|
| AutoETS ✓ | 0.066319 |
| AutoTheta | 0.068753 |
| MSTL | 0.072470 |
| MSTL_55 | 0.096400 |
| AutoARIMA | 0.121614 |
| MSTL_55_126 | 0.181864 |
| MSTL_126 | 0.211385 |
Forecast horizon: 60 days | Selected: AutoETS
| Forecast Reliability | |
|---|---|
| Score | 37% |
| H-stat | 2.41 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.123 |
| Excess Kurtosis | -1.25 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 10.418 |
| Revenue per Share | 1.079 |
| Market Cap | 1,834,934,144 |
| Forward P/E | 87.82 |
| Beta | 1.13 |
| Profit Margins | -126.33% |
| Website | https://www.zymeworks.com |
As of July 11, 2026, 4:05 a.m. EDT: Speculators are positioning for a volatile range-bound outcome rather than a directional breakout. Call open interest is heavily concentrated at the $30 strike, suggesting a speculative bet on a rally to that level, while put open interest is overwhelmingly stacked at the $22.50 strike, indicating a defensive floor. The massive volume of out-of-the-money puts relative to calls in the October expiration suggests fear of a significant drop below current levels, creating a 'long gamma' environment where the stock could snap back up quickly if it dips, but the heavy put wall acts as a psychological ceiling preventing a strong advance.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.9385768 |
| Address1 | 108 Patriot Drive |
| Address2 | Suite A |
| All Time High | 59.03 |
| All Time Low | 4.11 |
| Ask | 31.92 |
| Ask Size | 2 |
| Audit Risk | 8 |
| Average Analyst Rating | 1.2 - Strong Buy |
| Average Daily Volume10 Day | 762,580 |
| Average Daily Volume3 Month | 676,360 |
| Average Volume | 676,360 |
| Average Volume10Days | 762,580 |
| Beta | 1.126 |
| Bid | 18.39 |
| Bid Size | 2 |
| Board Risk | 8 |
| Book Value | 2.192 |
| City | Middletown |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 24.94 |
| Current Ratio | 10.819 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,782,777,600 |
| Day High | 25.79 |
| Day Low | 24.74 |
| Debt To Equity | 10.418 |
| Display Name | Zymeworks |
| Earnings Call Timestamp End | 1,778,185,800 |
| Earnings Call Timestamp Start | 1,778,185,800 |
| Earnings Timestamp | 1,778,184,000 |
| Earnings Timestamp End | 1,786,046,400 |
| Earnings Timestamp Start | 1,786,046,400 |
| Ebitda | -107,788,000 |
| Ebitda Margins | -1.32641 |
| Enterprise To Ebitda | -13.67 |
| Enterprise To Revenue | 18.133 |
| Enterprise Value | 1,473,510,144 |
| Eps Current Year | 1.4 |
| Eps Forward | 0.284 |
| Eps Trailing Twelve Months | -1.37 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 24.8491 |
| Fifty Day Average Change | 0.09090042 |
| Fifty Day Average Change Percent | 0.003658097 |
| Fifty Two Week Change Percent | 93.85768 |
| Fifty Two Week High | 29.75 |
| Fifty Two Week High Change | -4.8099995 |
| Fifty Two Week High Change Percent | -0.16168065 |
| Fifty Two Week Low | 11.51 |
| Fifty Two Week Low Change | 13.43 |
| Fifty Two Week Low Change Percent | 1.1668115 |
| Fifty Two Week Range | 11.51 - 29.75 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,493,386,200,000 |
| Float Shares | 67,994,693 |
| Forward Eps | 0.284 |
| Forward P E | 87.8169 |
| Free Cashflow | -45,503,000 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 243 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,782,864,000 |
| Gross Margins | -0.67012 |
| Gross Profits | -54,456,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.012990001 |
| Held Percent Institutions | 1.0289 |
| Implied Shares Outstanding | 73,573,945 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,022-12-16 |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Zymeworks Inc., a biotechnology company, develops biotherapeutics for the treatment of cancer, inflammation, and autoimmune diseases. The company's platforms include Azymetric multispecific antibody platform; Drug Conjugate platform that includes a suite of proprietary cytotoxins comprising topoisomerase and microtubulin inhibiting toxins, stable linkers, and conjugation technologies; EFECT platform, which consists of a set of modifications to the Fc region of antibodies; and ProTECT, a tumor-specific immune co-stimulation platform. Its lead product candidates include Ziihera (zanidatamab-hrii), a bispecific antibody targeting HER2-expressing tumors; zanidatamab for the treatment of neoadjuvant populations, breast cancer, and other HER2-expressing cancers; Pasritamig, a bispecific T cell engager targeting human kallikrein 2 for the treatment monotherapy and castration resistant prostate cancer; ZW191, a clinical- antibody-drug conjugates (ADC) that targets folate receptor alpha expressing tumors, including ovarian, endometrial, and non-small cell lung cancers; ZW251, a clinical-stage ADC molecule for the treatment of glypican 3 expressing hepatocellular carcinoma; ZW220, an ADC that targets NaPi2b-expressing NSCLC and ovarian cancer; ZW209, a novel TriTCE targeting Delta-like ligand 3 -expressing tumor cells for the treatment of solid tumors; and ZW1528, a bispecific molecule to treat chronic obstructive pulmonary disease. It has strategic partnerships and collaborations with Jazz Pharmaceuticals plc; Bristol- Myers Squibb company; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Merck Sharp & Dohme Research GmbH; and Janssen Biotech, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware. |
| Long Name | Zymeworks Inc. |
| Market | us_market |
| Market Cap | 1,834,934,144 |
| Market State | POSTPOST |
| Max Age | 86,400 |
| Message Board Id | finmb_43279463 |
| Most Recent Quarter | 1,774,915,200 |
| Net Income To Common | -102,656,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,904,093,695 |
| Number Of Analyst Opinions | 12 |
| Open | 25.79 |
| Operating Cashflow | -75,316,000 |
| Operating Margins | -19.56728 |
| Overall Risk | 9 |
| Payout Ratio | 0.0 |
| Phone | 302 274 8744 |
| Post Market Change | 0.0 |
| Post Market Change Percent | 0.0 |
| Post Market Price | 24.94 |
| Post Market Time | 1,783,981,120 |
| Previous Close | 25.88 |
| Price Eps Current Year | 17.814287 |
| Price Hint | 2 |
| Price To Book | 11.377738 |
| Price To Sales Trailing12 Months | 22.580193 |
| Profit Margins | -1.26326 |
| Quick Ratio | 10.362 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.16667 |
| Region | US |
| Regular Market Change | -0.939999 |
| Regular Market Change Percent | -3.63214 |
| Regular Market Day High | 25.79 |
| Regular Market Day Low | 24.74 |
| Regular Market Day Range | 24.74 - 25.79 |
| Regular Market Open | 25.79 |
| Regular Market Previous Close | 25.88 |
| Regular Market Price | 24.94 |
| Regular Market Time | 1,783,972,800 |
| Regular Market Volume | 340,708 |
| Return On Assets | -0.15775 |
| Return On Equity | -0.42023998 |
| Revenue Growth | -0.911 |
| Revenue Per Share | 1.079 |
| Sand P52 Week Change | 0.20847368 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 10 |
| Shares Outstanding | 73,023,061 |
| Shares Percent Shares Out | 0.059299998 |
| Shares Short | 4,364,318 |
| Shares Short Previous Month Date | 1,780,012,800 |
| Shares Short Prior Month | 4,527,668 |
| Short Name | Zymeworks Inc. |
| Short Percent Of Float | 0.088599995 |
| Short Ratio | 5.69 |
| Source Interval | 15 |
| State | DE |
| Symbol | ZYME |
| Target High Price | 58.0 |
| Target Low Price | 31.0 |
| Target Mean Price | 39.33333 |
| Target Median Price | 37.0 |
| Total Cash | 364,727,008 |
| Total Cash Per Share | 4.995 |
| Total Debt | 17,042,000 |
| Total Revenue | 81,263,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.37 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 23.489574 |
| Two Hundred Day Average Change | 1.4504261 |
| Two Hundred Day Average Change Percent | 0.061747655 |
| Type Disp | Equity |
| Volume | 340,708 |
| Website | https://www.zymeworks.com |
| Zip | 19,709 |