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Zevra Therapeutics, Inc. (ZVRA)

Healthcare | Biotechnology | Boston, United States | NasdaqGS
11.85 USD +0.11 (0.937%) ⇧ (Aug. 27, 2026, 4 p.m. EDT)
After hours: 11.71 -0.14 (-0.140%) ⇩ (Aug. 27, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 3:09 a.m. EDT

The investment case for Zevra is currently paralyzed by a severe disconnect between its pristine balance sheet and its deteriorating market reality. Fundamentally, the company holds a fortress-like position with negligible debt, massive cash reserves, and robust profitability metrics, yet the stock has suffered an 88% collapse over the last nine years. This long-term trajectory is not a temporary dislocation but a structural verdict by the market on the efficacy of its core asset, Arimoclomol, following the European Medicines Agency's rejection of its bid for Niemann-Pick Type C. While the recent surge in call volume suggests traders are hoping for a miraculous regulatory turnaround or new data to reverse this trend, the overwhelming put writing indicates that the majority of capital is betting against further downside. With no dividend to provide income and a history of repeated failures in key markets, the risk-reward profile remains skewed heavily toward the downside until the company can demonstrate a definitive path to commercial success in major jurisdictions.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.099072
AutoETS0.099072
MSTL0.099406
AutoTheta0.102773

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 38%
H-stat 2.71
Ljung-Box p 0.000
Jarque-Bera p 0.206
Excess Kurtosis -0.67
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.687
Revenue per Share 2.367
Market Cap 703,697,792
Trailing P/E 12.74
Forward P/E 11.29
Beta 0.92
Profit Margins 42.82%
Website https://www.zevra.com

As of Aug. 22, 2026, 3:09 a.m. EDT: Speculators are positioning defensively with heavy put volume and open interest at strikes significantly below the current price (e.g., $8.00 and $5.00 for December expirations), creating a 'floor' scenario. Conversely, call activity is concentrated near the money ($12.00-$13.00) with notable new flow at distant strikes ($20.00), suggesting a binary bet on regulatory approval or clinical data rather than a linear price appreciation thesis. Implied volatility is elevated relative to historical norms, reflecting uncertainty surrounding the recent European rejection.


Info Dump

Attribute Value
52 Week Change 0.30650496
Address1 101 Federal Street
Address2 Suite 103
All Time High 418.4
All Time Low 1.936
Ask 14.98
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 797,090
Average Daily Volume3 Month 1,525,892
Average Volume 1,525,892
Average Volume10Days 797,090
Beta 0.923
Bid 8.54
Bid Size 2
Board Risk 7
Book Value 3.668
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 11.85
Current Ratio 5.167
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 11.91
Day Low 11.6211
Debt To Equity 0.687
Display Name Zevra Therapeutics
Dividend Date 1,609,113,600
Earnings Call Timestamp End 1,785,961,800
Earnings Call Timestamp Start 1,785,961,800
Earnings Growth -0.884
Earnings Quarterly Growth -0.883
Earnings Timestamp 1,785,960,000
Earnings Timestamp End 1,793,822,400
Earnings Timestamp Start 1,793,822,400
Ebitda 40,553,000
Ebitda Margins 0.29803
Enterprise To Ebitda 11.926
Enterprise To Revenue 3.554
Enterprise Value 483,623,808
Eps Current Year 1.14
Eps Forward 1.05
Eps Trailing Twelve Months 0.93
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 12.1384
Fifty Day Average Change -0.2883997
Fifty Day Average Change Percent -0.023759285
Fifty Two Week Change Percent 30.650497
Fifty Two Week High 15.035
Fifty Two Week High Change -3.1849995
Fifty Two Week High Change Percent -0.211839
Fifty Two Week Low 7.16
Fifty Two Week Low Change 4.6900005
Fifty Two Week Low Change Percent 0.65502805
Fifty Two Week Range 7.16 - 15.035
Financial Currency USD
First Trade Date Milliseconds 1,429,191,000,000
Float Shares 53,902,658
Forward Eps 1.05
Forward P E 11.285715
Free Cashflow 48,381,124
Full Exchange Name NasdaqGS
Full Time Employees 61
Fullday Change 0.110001
Fullday Change Percent 0.936973
Fullday Price 11.71
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.95458
Gross Profits 129,891,000
Has Pre Post Market Data 1
Held Percent Insiders 0.01258
Held Percent Institutions 0.77142996
Implied Shares Outstanding 59,383,781
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,609,113,600
Last Split Factor 1:16
Long Business Summary Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 3 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 3 clinical trial to treat narcolepsy. The company is developing Celiprolol, an investigational product candidate that is under Phase 3 clinical trial for the treatment of vascular Ehlers Danlos syndrome. In addition, it offers AZSTARYS, a once-daily treatment for attention deficit and hyperactivity disorder in patients aged six years and older; OLPRUVA to treat urea cycle disorders; and MIPLYFFA for the treatment of niemann-pick disease type C, an ultra-rare neurodegenerative disease. The company has collaboration and license agreement with Commave Therapeutics SA to develop, manufacture and commercialize the company's product candidates containing SDX and d-methylphenidate; and license agreement with Acer and Relief Therapeutics, Inc. to develop and commercialize rights for OLPRUVA. The company was formerly known as KemPharm, Inc. and changed its name to Zevra Therapeutics, Inc. in February 2023. The company was incorporated in 2006 and is headquartered in Boston, Massachusetts.
Long Name Zevra Therapeutics, Inc.
Market us_market
Market Cap 703,697,792
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_65059726
Most Recent Quarter 1,782,777,600
Net Income To Common 57,247,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 697,462,507
Number Of Analyst Opinions 9
Open 11.74
Operating Cashflow 33,399,000
Operating Margins 0.42299
Overall Risk 8
Payout Ratio 0.0
Peg Ratio 10.67
Phone 888 958 1253
Post Market Change -0.14000034
Post Market Change Percent -1.1814375
Post Market Price 11.71
Post Market Time 1,787,873,403
Previous Close 11.74
Price Eps Current Year 10.394737
Price Hint 2
Price To Book 3.2306435
Price To Sales Trailing12 Months 5.1715484
Profit Margins 0.42818
Quick Ratio 5.018
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.22222
Region US
Regular Market Change 0.110001
Regular Market Change Percent 0.936973
Regular Market Day High 11.91
Regular Market Day Low 11.6211
Regular Market Day Range 11.6211 - 11.91
Regular Market Open 11.74
Regular Market Previous Close 11.74
Regular Market Price 11.85
Regular Market Time 1,787,860,800
Regular Market Volume 620,421
Return On Assets 0.08736
Return On Equity 0.34796003
Revenue Growth 0.533
Revenue Per Share 2.367
Sand P52 Week Change 0.1890428
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 59,383,781
Shares Percent Shares Out 0.109
Shares Short 6,470,662
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 7,795,667
Short Name Zevra Therapeutics, Inc.
Short Percent Of Float 0.1102
Short Ratio 4.73
Source Interval 15
State MA
Symbol ZVRA
Target High Price 35.0
Target Low Price 20.0
Target Mean Price 25.0
Target Median Price 24.0
Total Cash 221,570,000
Total Cash Per Share 3.731
Total Debt 1,496,000
Total Revenue 136,071,008
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.93
Trailing P E 12.741936
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 10.200475
Two Hundred Day Average Change 1.6495256
Two Hundred Day Average Change Percent 0.16171068
Type Disp Equity
Volume 620,421
Website https://www.zevra.com
Zip 2,110