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Zai Lab Limited (ZLAB)

Healthcare | Biotechnology | Pudong, China | NasdaqGM
26.82 USD +0.79 (3.035%) ⇧ (Aug. 27, 2026, 4 p.m. EDT)
After hours: 27.10 +0.28 (1.044%) ⇧ (Aug. 27, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:50 a.m. EDT

The investment case for Zai Lab is currently paralyzed by a severe fundamental disconnect. Despite a 'strong buy' analyst consensus and a recent surge in stock price (+99% YoY), the company is bleeding cash with negative free cash flow, shrinking revenues (-3%), and negative operating margins. The balance sheet is fragile, with debt-to-equity nearing 42% and no dividend support. This creates a dangerous dichotomy: the market is pricing in a turnaround based on the oncology pipeline, but the quarterly financials tell a story of deterioration. The short-term outlook remains neutral-to-cautious because the recent price rally has stalled, and the statistical forecasting models show no directional edge. More importantly, the options market is screaming caution; traders are buying deep out-of-the-money puts as insurance, indicating they expect volatility to turn negative soon. There is no momentum here to fuel a high-conviction entry yet. Long-term, the business quality is unproven. The multi-year trajectory shows a volatile rollercoaster rather than a sustained compounder, and the lack of profitability makes it impossible to rate as a core holding. Until the company demonstrates consistent revenue growth and a path to profitability, it remains a speculative bet on a future cure rather than a current investment in a profitable business.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.096439
AutoETS0.096439
MSTL0.097174
AutoTheta0.105380

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 35%
H-stat 9.03
Ljung-Box p 0.000
Jarque-Bera p 0.360
Excess Kurtosis 0.55
Attribute Value
Sector Healthcare
Debt to Equity Ratio 41.937
Revenue per Share 4.057
Market Cap 3,010,980,096
Forward P/E -12.71
Beta 0.78
Profit Margins -41.86%
Website https://www.zailaboratory.com

As of Aug. 22, 2026, 5:50 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in out-of-the-money puts (over 2,000 contracts at strikes below $20) compared to negligible call volume. While there is some new call flow at lower strikes ($15-$22.50), the overwhelming capital allocation is defensive, suggesting a fear of further decline rather than a bullish breakout.


Info Dump

Attribute Value
52 Week Change -0.19211668
Address1 Building B
Address2 899 Halei Road
All Time High 193.54
All Time Low 13.48
Ask 23.88
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 1,238,110
Average Daily Volume3 Month 1,026,196
Average Volume 1,026,196
Average Volume10Days 1,238,110
Beta 0.781
Bid 13.12
Bid Size 2
Book Value 5.963
City Pudong
Compensation As Of Epoch Date 1,767,139,200
Country China
Crypto Tradeable 0
Currency USD
Current Price 26.82
Current Ratio 2.133
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 27.2
Day Low 26.575
Debt To Equity 41.937
Display Name Zai Lab
Earnings Call Timestamp End 1,786,017,600
Earnings Call Timestamp Start 1,786,017,600
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -248,168,000
Ebitda Margins -0.55196
Enterprise To Ebitda -10.67
Enterprise To Revenue 5.89
Enterprise Value 2,648,034,304
Eps Current Year -2.19529
Eps Forward -2.11033
Eps Trailing Twelve Months -1.7
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 20.9354
Fifty Day Average Change 5.8845997
Fifty Day Average Change Percent 0.2810837
Fifty Two Week Change Percent -19.211668
Fifty Two Week High 34.72
Fifty Two Week High Change -7.9000015
Fifty Two Week High Change Percent -0.22753459
Fifty Two Week Low 15.96
Fifty Two Week Low Change 10.86
Fifty Two Week Low Change Percent 0.6804511
Fifty Two Week Range 15.96 - 34.72
Financial Currency USD
First Trade Date Milliseconds 1,505,914,200,000
Float Shares 96,831,867
Forward Eps -2.11033
Forward P E -12.708912
Free Cashflow -83,963,752
Full Exchange Name NasdaqGM
Full Time Employees 1,784
Fullday Change 0.789999
Fullday Change Percent 3.03496
Fullday Price 27.1
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.03778
Gross Profits 16,985,000
Has Pre Post Market Data 1
Held Percent Insiders 0.021540001
Held Percent Institutions 0.38386002
Implied Shares Outstanding 112,266,228
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammatory demyelinating polyneuropathy; NUZYRA for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections; Optune for glioblastoma multiforme; Qinlock for gastrointestinal stromal tumors; Xacduro for treating hospital-acquired and ventilator-associated bacterial pneumonia caused by a cinetobacter baumannii-calcoaceticus complex; and Augtyro for the treatment of ROS proto-oncogene 1 and non-small cell lung cancer. The company has a strategic collaboration with Tesaro, Inc., NovoCure Ltd., Deciphera Pharmaceuticals, LLC, Paratek Bermuda Ltd., argent BV, Turning Point Therapeutics, Inc., Entasis Therapeutics Holdings Inc., Karuna Therapeutics, Inc., Pfizer Inc., Amgen Inc., and with Boehringer Ingelheim GmbH. The company was incorporated in 2013 and is based in Pudong, China.
Long Name Zai Lab Limited
Market us_market
Market Cap 3,010,980,096
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_271123063
Most Recent Quarter 1,782,777,600
Net Income To Common -188,212,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,878,790,160
Number Of Analyst Opinions 12
Open 27.11
Operating Cashflow -133,384,000
Operating Margins -0.71948
Payout Ratio 0.0
Phone 86 21 6163 2588
Post Market Change 0.2800007
Post Market Change Percent 1.0439996
Post Market Price 27.1
Post Market Time 1,787,873,402
Previous Close 26.03
Price Eps Current Year -12.217064
Price Hint 2
Price To Book 4.497736
Price To Sales Trailing12 Months 6.696811
Profit Margins -0.41861
Quick Ratio 1.611
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.33333
Region US
Regular Market Change 0.789999
Regular Market Change Percent 3.03496
Regular Market Day High 27.2
Regular Market Day Low 26.575
Regular Market Day Range 26.575 - 27.2
Regular Market Open 27.11
Regular Market Previous Close 26.03
Regular Market Price 26.82
Regular Market Time 1,787,860,801
Regular Market Volume 597,324
Return On Assets -0.14745
Return On Equity -0.26911
Revenue Growth -0.033
Revenue Per Share 4.057
Sand P52 Week Change 0.18053913
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 112,266,228
Shares Percent Shares Out 0.0665
Shares Short 7,465,887
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 6,351,893
Short Name Zai Lab Limited
Short Percent Of Float 0.0679
Short Ratio 7.8
Source Interval 15
Symbol ZLAB
Target High Price 50.0
Target Low Price 24.25
Target Mean Price 33.14
Target Median Price 31.84
Total Cash 617,521,984
Total Cash Per Share 5.501
Total Debt 254,576,000
Total Revenue 449,614,016
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.7
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 19.674074
Two Hundred Day Average Change 7.1459255
Two Hundred Day Average Change Percent 0.36321533
Type Disp Equity
Volume 597,324
Website https://www.zailaboratory.com
Zip 201,203