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Zai Lab Limited (ZLAB)

Healthcare | Biotechnology | Pudong, China | NasdaqGM
24.99 USD +0.18 (0.726%) ⇧ (Oct. 9, 2026, 4 p.m. EDT)
After hours: 24.99

Short-term:★★☆☆☆Long-term:★⯪☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 6:29 a.m. EDT

The investment case for Zai Lab is currently fractured by deteriorating fundamentals and a lack of financial discipline. Despite a 'strong buy' analyst consensus driven by the company's oncology pipeline, the financial reality is stark: revenue is shrinking by 3.3%, operating margins are deeply negative at -72%, and the company is burning cash with no free cash flow generation. The balance sheet is fragile, with debt-to-equity nearing 42% and negative returns on both assets and equity. The price action reflects this uncertainty. While the stock has recovered somewhat from its lows, the trailing twelve-month performance shows a net decline, and the recent price history reveals a volatile, range-bound struggle without a clear upward trend. The absence of any dividend history confirms the company is reinvesting all capital into operations, which is standard for biotech but risky given the current burn rate. Options activity provides the clearest signal of market sentiment: traders are aggressively buying cheap put protection at strikes significantly below the current price, betting on further downside. This defensive positioning overrides the optimistic analyst targets, suggesting the market sees the current valuation as insufficiently safe against potential clinical setbacks or continued revenue erosion. Until the company demonstrates a path to profitability or stabilizes its revenue growth, the risk-reward profile remains skewed toward caution.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.307660
AutoARIMA0.312276
AutoETS0.312278
AutoTheta0.328396

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 31%
H-stat 1.17
Ljung-Box p 0.016
Jarque-Bera p 0.000
Excess Kurtosis 12.10
Attribute Value
Sector Healthcare
Debt to Equity Ratio 41.937
Revenue per Share 4.057
Market Cap 2,805,532,928
Forward P/E -11.84
Beta 0.72
Profit Margins -41.86%
Website https://www.zailaboratory.com

As of Oct. 10, 2026, 6:29 a.m. EDT: Speculators are positioning heavily for downside protection, evidenced by massive open interest in deep out-of-the-money puts (strikes 17.5 and 20) expiring late in 2026 and early 2027. This 'insurance' positioning suggests a fear of significant further declines. Conversely, call activity is concentrated near the money and slightly out-of-the-money, indicating a limited bullish thesis focused on modest recovery rather than a major breakout.


Info Dump

Attribute Value
52 Week Change -0.19980788
Address1 Building B
Address2 899 Halei Road
All Time High 193.54
All Time Low 13.48
Ask 23.88
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 805,720
Average Daily Volume3 Month 942,931
Average Volume 942,931
Average Volume10Days 805,720
Beta 0.724
Bid 13.12
Bid Size 2
Book Value 5.408
City Pudong
Compensation As Of Epoch Date 1,767,139,200
Country China
Crypto Tradeable 0
Currency USD
Current Price 24.99
Current Ratio 2.133
Custom Price Alert Confidence HIGH
Date Short Interest 1,789,430,400
Day High 25.88
Day Low 24.35
Debt To Equity 41.937
Display Name Zai Lab
Dividend Yield 0.0
Earnings Call Timestamp End 1,786,017,600
Earnings Call Timestamp Start 1,786,017,600
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -248,168,000
Ebitda Margins -0.55196
Enterprise To Ebitda -9.987
Enterprise To Revenue 5.513
Enterprise Value 2,478,512,128
Eps Current Year -2.1956
Eps Forward -2.11033
Eps Trailing Twelve Months -1.7
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 24.8734
Fifty Day Average Change 0.11660004
Fifty Day Average Change Percent 0.00468774
Fifty Two Week Change Percent -19.98079
Fifty Two Week High 31.85
Fifty Two Week High Change -6.8600006
Fifty Two Week High Change Percent -0.21538463
Fifty Two Week Low 15.96
Fifty Two Week Low Change 9.03
Fifty Two Week Low Change Percent 0.56578946
Fifty Two Week Range 15.96 - 31.85
Financial Currency USD
First Trade Date Milliseconds 1,505,914,200,000
Float Shares 97,110,287
Forward Eps -2.11033
Forward P E -11.841749
Free Cashflow -83,963,752
Full Exchange Name NasdaqGM
Full Time Employees 1,784
Fullday Change 0.1800003
Fullday Change Percent 0.7255151
Fullday Price 24.99
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.03778
Gross Profits 16,985,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0212
Held Percent Institutions 0.38464
Implied Shares Outstanding 112,266,228
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammatory demyelinating polyneuropathy; NUZYRA for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections; Optune for glioblastoma multiforme; Qinlock for gastrointestinal stromal tumors; Xacduro for treating hospital-acquired and ventilator-associated bacterial pneumonia caused by a cinetobacter baumannii-calcoaceticus complex; and Augtyro for the treatment of ROS proto-oncogene 1 and non-small cell lung cancer. The company has a strategic collaboration with Tesaro, Inc., NovoCure Ltd., Deciphera Pharmaceuticals, LLC, Paratek Bermuda Ltd., argent BV, Turning Point Therapeutics, Inc., Entasis Therapeutics Holdings Inc., Karuna Therapeutics, Inc., Pfizer Inc., Amgen Inc., and with Boehringer Ingelheim GmbH. The company was incorporated in 2013 and is based in Pudong, China.
Long Name Zai Lab Limited
Market us_market
Market Cap 2,805,532,928
Market State CLOSED
Max Age 86,400
Message Board Id finmb_271123063
Most Recent Quarter 1,782,777,600
Net Income To Common -188,212,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 3,014,480,974
Number Of Analyst Opinions 12
Open 24.82
Operating Cashflow -133,384,000
Operating Margins -0.71948
Phone 86 21 6163 2588
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 24.99
Post Market Time 1,791,576,072
Previous Close 24.81
Price Eps Current Year -11.381854
Price Hint 2
Price To Book 4.620932
Price To Sales Trailing12 Months 6.2398696
Profit Margins -0.41861
Quick Ratio 1.611
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.33333
Region US
Regular Market Change 0.1800003
Regular Market Change Percent 0.7255151
Regular Market Day High 25.88
Regular Market Day Low 24.35
Regular Market Day Range 24.35 - 25.88
Regular Market Open 24.82
Regular Market Previous Close 24.81
Regular Market Price 24.99
Regular Market Time 1,791,576,000
Regular Market Volume 1,024,847
Return On Assets -0.14745
Return On Equity -0.26911
Revenue Growth -0.033
Revenue Per Share 4.057
Sand P52 Week Change 0.17383456
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 112,266,228
Shares Percent Shares Out 0.0727
Shares Short 8,156,879
Shares Short Previous Month Date 1,786,665,600
Shares Short Prior Month 7,465,887
Short Name Zai Lab Limited
Short Percent Of Float 0.074099995
Short Ratio 8.05
Source Interval 15
Symbol ZLAB
Target High Price 50.0
Target Low Price 24.25
Target Mean Price 33.14
Target Median Price 31.84
Total Cash 617,521,984
Total Cash Per Share 5.501
Total Debt 254,576,000
Total Revenue 449,614,016
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.7
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 20.589926
Two Hundred Day Average Change 4.400074
Two Hundred Day Average Change Percent 0.21370034
Type Disp Equity
Volume 1,024,847
Website https://www.zailaboratory.com
Zip 201,203