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Xilio Therapeutics, Inc. (XLO)

Healthcare | Biotechnology | Waltham, United States | NasdaqCM
8.57 USD +0.22 (2.635%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 8.74 +0.17 (1.984%) ⇧ (April 17, 2026, 5:52 p.m. EDT)

Short-term: ☆☆☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:33 p.m. EDT

High short-term risk despite a recent speculative upgrade due to a crushing -5.98% directional forecast and a distressed reversal split situation; fundamentally unattractive long-term due to -80% profit margins, only $137M cash versus 2026 trial start timeline, and no earnings visibility.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.069594
MSTL0.089565
AutoARIMA0.094999
AutoETS0.095001

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 66%
H-stat 1.54
Ljung-Box p 0.000
Jarque-Bera p 0.136
Excess Kurtosis -0.80
Attribute Value
Sector Healthcare
Debt to Equity Ratio 19.715
Revenue per Share 9.66
Market Cap 49,556,116
Forward P/E -14.78
Beta -0.12
Profit Margins -80.05%
Website https://xiliotx.com

Info Dump

Attribute Value
52 Week Change -0.24890447
Address1 828 Winter Street
Address2 Suite 300
All Time High 391.3
All Time Low 6.468
Ask 10.72
Ask Size 2
Average Daily Volume10 Day 28,920
Average Daily Volume3 Month 39,658
Average Volume 39,658
Average Volume10Days 28,920
Beta -0.12
Bid 6.12
Bid Size 2
Book Value 7.785
City Waltham
Compensation As Of Epoch Date 1,735,603,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 8.57
Current Ratio 2.577
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 8.76
Day Low 8.31
Debt To Equity 19.715
Display Name Xilio Therapeutics
Earnings Timestamp End 1,754,911,858
Earnings Timestamp Start 1,754,479,858
Ebitda -40,441,000
Ebitda Margins -0.92403
Enterprise To Ebitda 2.003
Enterprise To Revenue -1.851
Enterprise Value -81,020,880
Eps Forward -0.58
Eps Trailing Twelve Months -4.19
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 7.93634
Fifty Day Average Change 0.63365984
Fifty Day Average Change Percent 0.07984283
Fifty Two Week Change Percent -24.890446
Fifty Two Week High 16.52
Fifty Two Week High Change -7.950001
Fifty Two Week High Change Percent -0.4812349
Fifty Two Week Low 6.468
Fifty Two Week Low Change 2.1019998
Fifty Two Week Low Change Percent 0.3249845
Fifty Two Week Range 6.468 - 16.52
Financial Currency USD
First Trade Date Milliseconds 1,634,909,400,000
Float Shares 3,446,377
Forward Eps -0.58
Forward P E -14.775862
Free Cashflow 8,027,250
Full Exchange Name NasdaqCM
Full Time Employees 76
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 43,766,000
Has Pre Post Market Data 1
Held Percent Insiders 0.29479998
Held Percent Institutions 0.35394
Implied Shares Outstanding 5,782,511
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-10-22
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,773,619,200
Last Split Factor 1:14
Long Business Summary Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies. The company's checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors. It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
Long Name Xilio Therapeutics, Inc.
Market us_market
Market Cap 49,556,116
Market State PREPRE
Max Age 86,400
Message Board Id finmb_365333564
Most Recent Quarter 1,767,139,200
Net Income To Common -35,036,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 49,556,119
Number Of Analyst Opinions 1
Open 8.61
Operating Cashflow -4,992,000
Operating Margins -0.86483
Payout Ratio 0.0
Phone 857 524 2466
Post Market Change 0.17000008
Post Market Change Percent 1.9836649
Post Market Price 8.74
Post Market Time 1,776,462,748
Previous Close 8.35
Price Hint 2
Price To Book 1.100835
Price To Sales Trailing12 Months 1.1322972
Profit Margins -0.80053
Quick Ratio 2.533
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.219999
Regular Market Change Percent 2.63472
Regular Market Day High 8.76
Regular Market Day Low 8.31
Regular Market Day Range 8.31 - 8.76
Regular Market Open 8.61
Regular Market Previous Close 8.35
Regular Market Price 8.57
Regular Market Time 1,776,456,000
Regular Market Volume 40,360
Return On Assets -0.23245001
Return On Equity -1.3253399
Revenue Growth 6.939
Revenue Per Share 9.66
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 5,782,511
Shares Percent Shares Out 0.031600002
Shares Short 182,492
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 150,981
Short Name Xilio Therapeutics, Inc.
Short Percent Of Float 0.0397
Short Ratio 3.8
Source Interval 15
State MA
Symbol XLO
Target High Price 20.0
Target Low Price 20.0
Target Mean Price 20.0
Target Median Price 20.0
Total Cash 137,531,008
Total Cash Per Share 23.784
Total Debt 6,954,000
Total Revenue 43,766,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.19
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 9.525535
Two Hundred Day Average Change -0.95553493
Two Hundred Day Average Change Percent -0.100313
Type Disp Equity
Volume 40,360
Website https://xiliotx.com
Zip 2,451