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Xilio Therapeutics, Inc. (XLO)

Healthcare | Biotechnology | Waltham, United States | NasdaqCM
9.22 USD +0.15 (1.598%) ⇧ (Oct. 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 10:46 a.m. EDT

The stock presents a classic biotech value trap where aggressive revenue growth masks a catastrophic failure in shareholder value creation. While the company boasts a staggering 131% revenue surge, the underlying business is bleeding capital at an alarming rate, with operating cash flow and free cash flow both deeply negative. This financial hemorrhage is compounded by a disastrous multi-year price trajectory; the asset has lost over 95% of its value since 2021, driven by three consecutive years of double-digit declines. Although the most recent annual report shows a marginal price recovery, this is insufficient to offset the structural deterioration evident in the balance sheet and the relentless drop in share price. The recent 1-for-14 reverse split further signals distress, likely an attempt to prop up the per-share price rather than improve the business. With no dividend to provide income and a balance sheet that cannot sustain operations without constant capital raising, the long-term outlook remains bleak despite the optimistic analyst targets.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.019940
AutoETS0.022478
AutoARIMA0.031274
AutoTheta0.034874

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 33%
H-stat 0.11
Ljung-Box p 0.000
Jarque-Bera p 0.007
Excess Kurtosis 1.33
Attribute Value
Sector Healthcare
Debt to Equity Ratio 8.722
Revenue per Share 9.74
Market Cap 60,669,012
Forward P/E -15.90
Beta -0.12
Profit Margins -34.06%
Website https://xiliotx.com

Info Dump

Attribute Value
52 Week Change -0.14596272
Address1 828 Winter Street
Address2 Suite 300
All Time High 391.3
All Time Low 6.468
Ask 9.25
Ask Size 1
Average Daily Volume10 Day 7,780
Average Daily Volume3 Month 17,871
Average Volume 17,871
Average Volume10Days 7,780
Beta -0.122
Bid 8.86
Bid Size 1
Book Value 7.785
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 9.22
Current Ratio 4.254
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 9.22
Day Low 8.855
Debt To Equity 8.722
Display Name Xilio Therapeutics
Dividend Yield 0.0
Earnings Timestamp End 1,754,911,858
Earnings Timestamp Start 1,754,479,858
Ebitda -30,030,000
Ebitda Margins -0.46855
Enterprise To Ebitda 2.332
Enterprise To Revenue -1.093
Enterprise Value -70,022,112
Eps Forward -0.58
Eps Trailing Twelve Months -0.6
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 9.06566
Fifty Day Average Change 0.15433979
Fifty Day Average Change Percent 0.01702466
Fifty Two Week Change Percent -14.5962715
Fifty Two Week High 12.586
Fifty Two Week High Change -3.3660002
Fifty Two Week High Change Percent -0.26744002
Fifty Two Week Low 6.468
Fifty Two Week Low Change 2.7520003
Fifty Two Week Low Change Percent 0.42547935
Fifty Two Week Range 6.468 - 12.586
Financial Currency USD
First Trade Date Milliseconds 1,634,909,400,000
Float Shares 3,402,531
Forward Eps -0.58
Forward P E -15.896553
Free Cashflow -37,562,000
Full Exchange Name NasdaqCM
Full Time Employees 76
Fullday Change 0.14500046
Fullday Change Percent 1.635651
Fullday Price 9.22
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.83156997
Gross Profits 53,297,000
Has Pre Post Market Data 1
Held Percent Insiders 0.25982
Held Percent Institutions 0.50164
Implied Shares Outstanding 6,580,153
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-10-22
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,773,619,200
Last Split Factor 1:14
Long Business Summary Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of masked immuno-oncology therapies. The company's pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
Long Name Xilio Therapeutics, Inc.
Market us_market
Market Cap 60,669,012
Market State POST
Max Age 86,400
Message Board Id finmb_365333564
Most Recent Quarter 1,782,777,600
Net Income To Common -21,829,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 58,826,567
Number Of Analyst Opinions 1
Open 9.05
Operating Cashflow -60,598,000
Operating Margins -0.18676001
Phone 857 524 2466
Previous Close 9.075
Price Hint 2
Price To Book 1.1843289
Price To Sales Trailing12 Months 0.94659257
Profit Margins -0.34058997
Quick Ratio 4.153
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.14500046
Regular Market Change Percent 1.5978012
Regular Market Day High 9.22
Regular Market Day Low 8.855
Regular Market Day Range 8.855 - 9.22
Regular Market Open 9.05
Regular Market Previous Close 9.075
Regular Market Price 9.22
Regular Market Time 1,791,921,600
Regular Market Volume 17,736
Return On Assets -0.13611001
Return On Equity -0.55030996
Revenue Growth 1.312
Revenue Per Share 9.74
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 6,580,153
Shares Percent Shares Out 0.0623
Shares Short 410,050
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 418,277
Short Name Xilio Therapeutics, Inc.
Short Percent Of Float 0.0696
Short Ratio 38.99
Source Interval 15
State MA
Symbol XLO
Target High Price 20.0
Target Low Price 20.0
Target Mean Price 20.0
Target Median Price 20.0
Total Cash 136,040,000
Total Cash Per Share 20.674
Total Debt 6,303,000
Total Revenue 64,092,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.6
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.57325
Two Hundred Day Average Change 0.64675045
Two Hundred Day Average Change Percent 0.07543819
Type Disp Equity
Volume 17,736
Website https://xiliotx.com
Zip 2,451