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X4 Pharmaceuticals, Inc. (XFOR)

Healthcare | Biotechnology | Boston, United States | NasdaqCM
4.04 USD -0.19 (-4.492%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 4.01 -0.03 (-0.030%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:13 a.m. EDT

The investment case here is defined by a stark disconnect between the company's precarious financial reality and the aggressive optimism of retail traders. Fundamentally, this is a distressed biotech play: revenue has collapsed by over 80% year-over-year, operating cash flow is deeply negative, and the stock has erased nearly 99% of its value over the last seven years. While the balance sheet remains technically solvent due to substantial cash reserves relative to debt, the business model is currently failing to generate income, and the forward P/E is negative, signaling no earnings visibility. The 'strong buy' analyst consensus appears to be a reaction to potential catalysts like FDA approvals rather than current operational performance. Short-term, the stock is hovering near neutral territory, caught between the drag of deteriorating fundamentals and the spark of speculative buying. The statistical forecast models a slight downside drift, which aligns with the lack of genuine institutional accumulation in the options chain. The massive call open interest at the $7.50 strike represents a lottery ticket for a binary event, not a conviction trade in the current business trajectory. For a long-term holder, the multi-year decline is a warning sign that the market has already priced in the failure of the current strategy. There is no dividend to provide a floor, and without a proven path to profitability or a clear turnaround in revenue growth, the risk of permanent capital loss remains high.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.055941
MSTL0.077261
AutoTheta0.080331
AutoETS0.080736

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 51%
H-stat 0.92
Ljung-Box p 0.000
Jarque-Bera p 0.075
Excess Kurtosis 1.14
Attribute Value
Sector Healthcare
Debt to Equity Ratio 49.676
Revenue per Share 0.156
Market Cap 400,552,832
Trailing P/E 2.83
Forward P/E -5.35
Beta 0.39
Website https://www.x4pharma.com

As of Aug. 22, 2026, 2:13 a.m. EDT: Speculators are positioning for a significant upside move over the next few months, evidenced by heavy open interest in December $7.50 calls compared to minimal put activity. However, this bullish positioning is concentrated in deep out-of-the-money strikes where volume barely exceeds open interest, suggesting speculative hope rather than a robust institutional buildup. The immediate term shows mixed signals with elevated implied volatility on near-term puts versus flat call volume, indicating a wait-and-see attitude for the next week.


Info Dump

Attribute Value
52 Week Change 0.21902013
Address1 61 North Beacon Street
Address2 4th Floor
All Time High 5,164.92
All Time Low 1.35
Ask 5.19
Ask Size 2
Average Daily Volume10 Day 647,930
Average Daily Volume3 Month 779,219
Average Volume 779,219
Average Volume10Days 647,930
Beta 0.391
Bid 2.99
Bid Size 2
Book Value 1.617
City Boston
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.04
Current Ratio 11.301
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 4.23
Day Low 4.0
Debt To Equity 49.676
Display Name X4 Pharmaceuticals
Dividend Date 1,552,521,600
Earnings Call Timestamp End 1,746,102,600
Earnings Call Timestamp Start 1,746,102,600
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -79,004,000
Ebitda Margins 0.0
Enterprise To Ebitda -3.415
Enterprise To Revenue 17.026
Enterprise Value 269,807,840
Eps Current Year -0.668
Eps Forward -0.755
Eps Trailing Twelve Months 1.43
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 4.086
Fifty Day Average Change -0.046000004
Fifty Day Average Change Percent -0.011257955
Fifty Two Week Change Percent 21.902012
Fifty Two Week High 4.83
Fifty Two Week High Change -0.78999996
Fifty Two Week High Change Percent -0.16356108
Fifty Two Week Low 2.8
Fifty Two Week Low Change 1.24
Fifty Two Week Low Change Percent 0.44285715
Fifty Two Week Range 2.8 - 4.83
Financial Currency USD
First Trade Date Milliseconds 1,510,842,600,000
Float Shares 62,801,530
Forward Eps -0.755
Forward P E -5.350993
Free Cashflow -53,310,876
Full Exchange Name NasdaqCM
Full Time Employees 45
Fullday Change -0.19
Fullday Change Percent -4.49173
Fullday Price 4.01
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.81511
Gross Profits 12,917,000
Has Pre Post Market Data 1
Held Percent Insiders 0.0044
Held Percent Institutions 1.00139
Implied Shares Outstanding 99,146,743
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,745,798,400
Last Split Factor 1:30
Long Business Summary X4 Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases of the immune system. It offers XOLREMDI, an orally small-molecule selective antagonist of chemokine receptor CXCR4, which is in phase 3 clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. It has a license agreement with Abbisko Therapeutics Co Ltd. to manufacture and distribute XOLREMDI in mainland China, Taiwan, Hong Kong and Macau; Norgine to develop, manufacture, and commercialize mavorixafor in Europe, Australia, and New Zealand; and Genzyme Corporation for CXCR4 receptor to develop and commercialize products containing licensed compounds for all therapeutic, prophylactic and diagnostic uses. The company is headquartered in Boston, Massachusetts.
Long Name X4 Pharmaceuticals, Inc.
Market us_market
Market Cap 400,552,832
Market State CLOSED
Max Age 86,400
Message Board Id finmb_283397098
Most Recent Quarter 1,782,777,600
Net Income To Common -90,138,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 419,390,722
Number Of Analyst Opinions 5
Open 4.22
Operating Cashflow -83,736,000
Operating Margins -1.86134
Payout Ratio 0.0
Phone 857 529 8300
Post Market Change -0.029999733
Post Market Change Percent -0.74256766
Post Market Price 4.01
Post Market Time 1,787,959,804
Previous Close 4.23
Price Eps Current Year -6.0479045
Price Hint 4
Price To Book 2.4984539
Price To Sales Trailing12 Months 25.276257
Profit Margins 0.0
Quick Ratio 10.845
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.19
Regular Market Change Percent -4.49173
Regular Market Day High 4.23
Regular Market Day Low 4.0
Regular Market Day Range 4.0 - 4.23
Regular Market Open 4.22
Regular Market Previous Close 4.23
Regular Market Price 4.04
Regular Market Time 1,787,947,201
Regular Market Volume 356,154
Return On Assets -0.28149
Return On Equity -1.13079
Revenue Growth 3.463
Revenue Per Share 0.156
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 99,146,743
Shares Percent Shares Out 0.0723
Shares Short 7,164,662
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 6,501,966
Short Name X4 Pharmaceuticals, Inc.
Short Percent Of Float 0.072399996
Short Ratio 10.24
Source Interval 15
State MA
Symbol XFOR
Target High Price 13.0
Target Low Price 10.0
Target Mean Price 11.6
Target Median Price 12.0
Total Cash 207,968,992
Total Cash Per Share 2.098
Total Debt 77,224,000
Total Revenue 15,847,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 1.43
Trailing P E 2.8251748
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 3.929075
Two Hundred Day Average Change 0.11092496
Two Hundred Day Average Change Percent 0.028231826
Type Disp Equity
Volume 356,154
Website https://www.x4pharma.com
Zip 2,134