Xeris Biopharma Holdings, Inc. (XERS)Healthcare | Drug Manufacturers - Specialty & Generic | Chicago, United States | NasdaqGS
10.20 USD
-0.26
(-2.486%) ⇩
(Oct. 13, 2026, 4 p.m.
EDT)
After hours: 10.18 -0.02 (-0.020%) ⇩ (Oct. 13, 2026, 4:21 p.m. EDT) |
Hot Take ↕ | Oct. 10, 2026, 11:29 a.m. EDT
The investment case here is a classic tale of a turnaround story where the market has priced in a massive recovery, yet the fundamentals remain fragile. On the long-term side, the company shows a compelling narrative: revenue growth has accelerated dramatically (+187% last year), gross margins are healthy at 86%, and the balance sheet is manageable with positive operating cash flow. However, the multi-year price trajectory tells a different story; the stock is down nearly 55% over the last seven years, indicating that the market has historically struggled to value this business despite occasional operational wins. This disconnect creates a 'value trap' risk where the cheap price masks deteriorating competitive moats or execution issues. Short-term, the sentiment is aggressively optimistic. The options chain screams bullishness, with heavy positioning in calls and almost no hedging via puts. This suggests traders are betting on a catalyst—perhaps a patent win or drug approval—to unlock the current valuation. Yet, the statistical forecasting model offers zero guidance, showing a flat expected return with low confidence, which highlights the noise in the price action. The recent price action confirms this volatility, swinging wildly between $8.50 and $10.50. While the analyst consensus is a 'strong buy,' relying on such a rating for a biotech with negative earnings and a history of steep declines is dangerous. The stock is currently trading at a premium to its historical averages, making a 5-star long-term buy unwarranted. It warrants a cautious hold for those willing to ride the volatility, but the lack of a dividend and the precarious earnings situation prevent a high-conviction entry. |
| Model | MAE |
|---|---|
| AutoETS ✓ | 0.054200 |
| MSTL | 0.055829 |
| AutoTheta | 0.090069 |
| AutoARIMA | 0.128550 |
Forecast horizon: 45 days | Selected: AutoETS
| Forecast Reliability | |
|---|---|
| Score | 38% |
| H-stat | 5.80 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.662 |
| Excess Kurtosis | 0.56 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Revenue per Share | 1.993 |
| Market Cap | 1,859,667,072 |
| Forward P/E | 27.57 |
| Beta | 0.84 |
| Profit Margins | -5.12% |
| Previous Name | Xeris Pharmaceuticals, Inc. |
| Website | https://www.xerispharma.com |
As of Oct. 10, 2026, 11:29 a.m. EDT: Speculators are overwhelmingly bullish, with open interest heavily concentrated in out-of-the-money calls (strikes $10-$12.50) while put activity is negligible and confined to deep strikes. Implied volatility is elevated for near-term expirations, suggesting traders expect significant upside movement or binary event risk rather than downside protection.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.28817737 |
| Address1 | 1,375 West Fulton Street |
| Address2 | Suite 1300 |
| All Time High | 27.98 |
| All Time Low | 0.97 |
| Ask | 13.0 |
| Ask Size | 2 |
| Audit Risk | 5 |
| Average Analyst Rating | 1.4 - Strong Buy |
| Average Daily Volume10 Day | 4,404,830 |
| Average Daily Volume3 Month | 2,187,350 |
| Average Volume | 2,187,350 |
| Average Volume10Days | 4,404,830 |
| Beta | 0.838 |
| Bid | 7.52 |
| Bid Size | 2 |
| Board Risk | 8 |
| Book Value | -0.056 |
| City | Chicago |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 10.2 |
| Current Ratio | 1.449 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,790,726,400 |
| Day High | 10.5 |
| Day Low | 10.15 |
| Display Name | Xeris Biopharma |
| Dividend Yield | 0.0 |
| Earnings Call Timestamp End | 1,786,019,400 |
| Earnings Call Timestamp Start | 1,786,019,400 |
| Earnings Timestamp | 1,786,019,400 |
| Earnings Timestamp End | 1,793,881,800 |
| Earnings Timestamp Start | 1,793,881,800 |
| Ebitda | 48,769,000 |
| Ebitda Margins | 0.1454 |
| Enterprise To Ebitda | 42.543 |
| Enterprise To Revenue | 6.186 |
| Enterprise Value | 2,074,765,440 |
| Eps Current Year | -0.01667 |
| Eps Forward | 0.37 |
| Eps Trailing Twelve Months | -0.1 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 15 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 8.6934 |
| Fifty Day Average Change | 1.5065994 |
| Fifty Day Average Change Percent | 0.17330381 |
| Fifty Two Week Change Percent | 28.817738 |
| Fifty Two Week High | 11.33 |
| Fifty Two Week High Change | -1.1300001 |
| Fifty Two Week High Change Percent | -0.09973523 |
| Fifty Two Week Low | 5.25 |
| Fifty Two Week Low Change | 4.95 |
| Fifty Two Week Low Change Percent | 0.9428571 |
| Fifty Two Week Range | 5.25 - 11.33 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,529,587,800,000 |
| Float Shares | 176,066,720 |
| Forward Eps | 0.37 |
| Forward P E | 27.567566 |
| Free Cashflow | 52,450,124 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 435 |
| Fullday Change | -0.27999973 |
| Fullday Change Percent | -2.6768618 |
| Fullday Price | 10.18 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,790,812,800 |
| Gross Margins | 0.86574996 |
| Gross Profits | 290,384,992 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.03029 |
| Held Percent Institutions | 0.60699004 |
| Implied Shares Outstanding | 182,320,306 |
| Industry | Drug Manufacturers - Specialty & Generic |
| Industry Disp | Drug Manufacturers - Specialty & Generic |
| Industry Key | drug-manufacturers-specialty-generic |
| Is Earnings Date Estimate | 0 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois. |
| Long Name | Xeris Biopharma Holdings, Inc. |
| Market | us_market |
| Market Cap | 1,859,667,072 |
| Market State | POST |
| Max Age | 86,400 |
| Message Board Id | finmb_105901792 |
| Most Recent Quarter | 1,782,777,600 |
| Name Change Date | 2,026-10-13 |
| Net Income To Common | -17,165,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,579,805,451 |
| Number Of Analyst Opinions | 7 |
| Open | 10.41 |
| Operating Cashflow | 56,608,000 |
| Operating Margins | 0.05617 |
| Overall Risk | 8 |
| Payout Ratio | 0.0 |
| Phone | 844 445 5704 |
| Post Market Change | -0.019999504 |
| Post Market Change Percent | -0.19607358 |
| Post Market Price | 10.18 |
| Post Market Time | 1,791,922,907 |
| Prev Name | Xeris Pharmaceuticals, Inc. |
| Previous Close | 10.46 |
| Price Eps Current Year | -611.8776 |
| Price Hint | 2 |
| Price To Book | -182.14285 |
| Price To Sales Trailing12 Months | 5.544393 |
| Profit Margins | -0.05118 |
| Quick Ratio | 0.949 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.42857 |
| Region | US |
| Regular Market Change | -0.26000023 |
| Regular Market Change Percent | -2.4856617 |
| Regular Market Day High | 10.5 |
| Regular Market Day Low | 10.15 |
| Regular Market Day Range | 10.15 - 10.5 |
| Regular Market Open | 10.41 |
| Regular Market Previous Close | 10.46 |
| Regular Market Price | 10.2 |
| Regular Market Time | 1,791,921,600 |
| Regular Market Volume | 2,217,267 |
| Return On Assets | 0.06127 |
| Revenue Growth | 0.287 |
| Revenue Per Share | 1.993 |
| Sand P52 Week Change | 0.17502642 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 182,320,306 |
| Shares Percent Shares Out | 0.0395 |
| Shares Short | 7,202,379 |
| Shares Short Previous Month Date | 1,788,134,400 |
| Shares Short Prior Month | 8,041,258 |
| Short Name | Xeris Biopharma Holdings, Inc. |
| Short Percent Of Float | 0.040799998 |
| Short Ratio | 2.45 |
| Source Interval | 15 |
| State | IL |
| Symbol | XERS |
| Target High Price | 18.0 |
| Target Low Price | 8.0 |
| Target Mean Price | 12.85714 |
| Target Median Price | 12.0 |
| Total Cash | 121,747,000 |
| Total Cash Per Share | 0.668 |
| Total Debt | 289,441,984 |
| Total Revenue | 335,414,016 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -0.1 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 7.28945 |
| Two Hundred Day Average Change | 2.9105496 |
| Two Hundred Day Average Change Percent | 0.39928246 |
| Type Disp | Equity |
| Volume | 2,217,267 |
| Website | https://www.xerispharma.com |
| Zip | 60,607 |