Xeris Biopharma Holdings, Inc. (XERS)Healthcare | Drug Manufacturers - Specialty & Generic | Chicago, United States | NasdaqGS
8.16 USD
-0.18
(-2.158%) ⇩
(July 13, 2026, 4 p.m.
EDT)
|
Hot Take ↕ | July 11, 2026, 2:56 a.m. EDT
The immediate outlook is driven by a powerful confluence of technical momentum and speculative positioning. The stock has surged nearly 23% over the last fifty days, breaking above its moving averages, which aligns perfectly with the aggressive call buying seen in the options chain. Speculators are clearly betting on a continuation of this trend, targeting the $10 level where significant open interest sits. This creates a high-conviction short-term bullish case, supported by the recent catalyst of a patent win and extended exclusivity on Keveyis. However, the long-term picture remains precarious due to the company's precarious financial structure. While the business shows signs of recovery with a massive 118% revenue jump last year and a forward P/E that looks reasonable relative to current earnings, the balance sheet is a ticking time bomb. The company carries nearly $260 million in debt against only $112 million in cash, resulting in a debt-to-equity ratio of nearly 2,000%. This leverage makes the stock extremely sensitive to any regulatory setbacks or delays in drug development. The market is currently pricing in a successful path to profitability, but the lack of a dividend and the thin margin of safety regarding liquidity mean this is a high-risk, high-reward play rather than a stable investment. |
| Model | MAE |
|---|---|
| AutoTheta ✓ | 0.072337 |
| AutoARIMA | 0.086755 |
| AutoETS | 0.087028 |
| MSTL | 0.088014 |
Forecast horizon: 45 days | Selected: AutoTheta
| Forecast Reliability | |
|---|---|
| Score | 30% |
| H-stat | 25.73 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.020 |
| Excess Kurtosis | 0.24 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 1987.188 |
| Revenue per Share | 1.909 |
| Market Cap | 1,408,759,040 |
| Trailing P/E | 116.57 |
| Forward P/E | 20.79 |
| Beta | 0.85 |
| Profit Margins | 3.81% |
| Previous Name | Xeris Pharmaceuticals, Inc. |
| Website | https://www.xerispharma.com |
As of July 11, 2026, 2:56 a.m. EDT: Speculators are heavily positioned for upside, evidenced by massive open interest in out-of-the-money calls at the $10 strike compared to negligible put volume. The call chain shows significant interest in $10 targets across multiple expirations, while put activity is almost entirely concentrated in deep out-of-the-money strikes ($5), suggesting a bullish bias rather than hedging against a crash.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.5330882 |
| Address1 | 1,375 West Fulton Street |
| Address2 | Suite 1300 |
| All Time High | 27.98 |
| All Time Low | 0.97 |
| Ask | 10.4 |
| Ask Size | 2 |
| Audit Risk | 5 |
| Average Analyst Rating | 1.4 - Strong Buy |
| Average Daily Volume10 Day | 3,026,060 |
| Average Daily Volume3 Month | 1,871,786 |
| Average Volume | 1,871,786 |
| Average Volume10Days | 3,026,060 |
| Beta | 0.85 |
| Bid | 5.94 |
| Bid Size | 2 |
| Board Risk | 7 |
| Book Value | 0.082 |
| City | Chicago |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 8.16 |
| Current Ratio | 2.122 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,782,777,600 |
| Day High | 8.345 |
| Day Low | 8.05 |
| Debt To Equity | 1,987.188 |
| Display Name | Xeris Biopharma |
| Earnings Call Timestamp End | 1,778,157,000 |
| Earnings Call Timestamp Start | 1,778,157,000 |
| Earnings Timestamp | 1,778,157,000 |
| Earnings Timestamp End | 1,786,019,400 |
| Earnings Timestamp Start | 1,786,019,400 |
| Ebitda | 48,080,000 |
| Ebitda Margins | 0.15271 |
| Enterprise To Ebitda | 32.354 |
| Enterprise To Revenue | 4.941 |
| Enterprise Value | 1,555,562,112 |
| Eps Current Year | 0.14 |
| Eps Forward | 0.3925 |
| Eps Trailing Twelve Months | 0.07 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 6.8048 |
| Fifty Day Average Change | 1.3551998 |
| Fifty Day Average Change Percent | 0.19915351 |
| Fifty Two Week Change Percent | 53.308823 |
| Fifty Two Week High | 10.08 |
| Fifty Two Week High Change | -1.9200001 |
| Fifty Two Week High Change Percent | -0.1904762 |
| Fifty Two Week Low | 4.87 |
| Fifty Two Week Low Change | 3.29 |
| Fifty Two Week Low Change Percent | 0.6755647 |
| Fifty Two Week Range | 4.87 - 10.08 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,529,587,800,000 |
| Float Shares | 166,280,195 |
| Forward Eps | 0.3925 |
| Forward P E | 20.789808 |
| Free Cashflow | 42,205,376 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 435 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,782,864,000 |
| Gross Margins | 0.85893 |
| Gross Profits | 270,438,016 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.033800002 |
| Held Percent Institutions | 0.62462 |
| Implied Shares Outstanding | 172,642,055 |
| Industry | Drug Manufacturers - Specialty & Generic |
| Industry Disp | Drug Manufacturers - Specialty & Generic |
| Industry Key | drug-manufacturers-specialty-generic |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois. |
| Long Name | Xeris Biopharma Holdings, Inc. |
| Market | us_market |
| Market Cap | 1,408,759,040 |
| Market State | PRE |
| Max Age | 86,400 |
| Message Board Id | finmb_105901792 |
| Most Recent Quarter | 1,774,915,200 |
| Name Change Date | 2,026-07-13 |
| Net Income To Common | 12,008,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,408,759,168 |
| Number Of Analyst Opinions | 7 |
| Open | 8.34 |
| Operating Cashflow | 48,527,000 |
| Operating Margins | 0.09523 |
| Overall Risk | 7 |
| Payout Ratio | 0.0 |
| Phone | 844 445 5704 |
| Pre Market Change | -0.03999996 |
| Pre Market Change Percent | -0.49019563 |
| Pre Market Price | 8.12 |
| Pre Market Time | 1,784,019,428 |
| Prev Name | Xeris Pharmaceuticals, Inc. |
| Previous Close | 8.34 |
| Price Eps Current Year | 58.285713 |
| Price Hint | 2 |
| Price To Book | 99.51219 |
| Price To Sales Trailing12 Months | 4.474339 |
| Profit Margins | 0.03814 |
| Quick Ratio | 1.417 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.42857 |
| Region | US |
| Regular Market Change | -0.18 |
| Regular Market Change Percent | -2.15828 |
| Regular Market Day High | 8.345 |
| Regular Market Day Low | 8.05 |
| Regular Market Day Range | 8.05 - 8.345 |
| Regular Market Open | 8.34 |
| Regular Market Previous Close | 8.34 |
| Regular Market Price | 8.16 |
| Regular Market Time | 1,783,972,800 |
| Regular Market Volume | 1,461,452 |
| Return On Assets | 0.06343 |
| Revenue Growth | 0.383 |
| Revenue Per Share | 1.909 |
| Sand P52 Week Change | 0.20847368 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 172,642,055 |
| Shares Percent Shares Out | 0.0739 |
| Shares Short | 12,760,034 |
| Shares Short Previous Month Date | 1,780,012,800 |
| Shares Short Prior Month | 12,514,253 |
| Short Name | Xeris Biopharma Holdings, Inc. |
| Short Percent Of Float | 0.0765 |
| Short Ratio | 6.2 |
| Source Interval | 15 |
| State | IL |
| Symbol | XERS |
| Target High Price | 18.0 |
| Target Low Price | 8.0 |
| Target Mean Price | 11.28571 |
| Target Median Price | 10.0 |
| Total Cash | 111,750,000 |
| Total Cash Per Share | 0.647 |
| Total Debt | 258,552,992 |
| Total Revenue | 314,852,992 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | 0.07 |
| Trailing P E | 116.57143 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 7.05725 |
| Two Hundred Day Average Change | 1.1027498 |
| Two Hundred Day Average Change Percent | 0.15625772 |
| Type Disp | Equity |
| Volume | 1,461,452 |
| Website | https://www.xerispharma.com |
| Zip | 60,607 |