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Xeris Biopharma Holdings, Inc. (XERS)

Healthcare | Drug Manufacturers - Specialty & Generic | Chicago, United States | NasdaqGS
10.20 USD -0.26 (-2.486%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)
After hours: 10.18 -0.02 (-0.020%) ⇩ (Oct. 13, 2026, 4:21 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 11:29 a.m. EDT

The investment case here is a classic tale of a turnaround story where the market has priced in a massive recovery, yet the fundamentals remain fragile. On the long-term side, the company shows a compelling narrative: revenue growth has accelerated dramatically (+187% last year), gross margins are healthy at 86%, and the balance sheet is manageable with positive operating cash flow. However, the multi-year price trajectory tells a different story; the stock is down nearly 55% over the last seven years, indicating that the market has historically struggled to value this business despite occasional operational wins. This disconnect creates a 'value trap' risk where the cheap price masks deteriorating competitive moats or execution issues. Short-term, the sentiment is aggressively optimistic. The options chain screams bullishness, with heavy positioning in calls and almost no hedging via puts. This suggests traders are betting on a catalyst—perhaps a patent win or drug approval—to unlock the current valuation. Yet, the statistical forecasting model offers zero guidance, showing a flat expected return with low confidence, which highlights the noise in the price action. The recent price action confirms this volatility, swinging wildly between $8.50 and $10.50. While the analyst consensus is a 'strong buy,' relying on such a rating for a biotech with negative earnings and a history of steep declines is dangerous. The stock is currently trading at a premium to its historical averages, making a 5-star long-term buy unwarranted. It warrants a cautious hold for those willing to ride the volatility, but the lack of a dividend and the precarious earnings situation prevent a high-conviction entry.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.054200
MSTL0.055829
AutoTheta0.090069
AutoARIMA0.128550

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 38%
H-stat 5.80
Ljung-Box p 0.000
Jarque-Bera p 0.662
Excess Kurtosis 0.56
Attribute Value
Sector Healthcare
Revenue per Share 1.993
Market Cap 1,859,667,072
Forward P/E 27.57
Beta 0.84
Profit Margins -5.12%
Previous Name Xeris Pharmaceuticals, Inc.
Website https://www.xerispharma.com

As of Oct. 10, 2026, 11:29 a.m. EDT: Speculators are overwhelmingly bullish, with open interest heavily concentrated in out-of-the-money calls (strikes $10-$12.50) while put activity is negligible and confined to deep strikes. Implied volatility is elevated for near-term expirations, suggesting traders expect significant upside movement or binary event risk rather than downside protection.


Info Dump

Attribute Value
52 Week Change 0.28817737
Address1 1,375 West Fulton Street
Address2 Suite 1300
All Time High 27.98
All Time Low 0.97
Ask 13.0
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 4,404,830
Average Daily Volume3 Month 2,187,350
Average Volume 2,187,350
Average Volume10Days 4,404,830
Beta 0.838
Bid 7.52
Bid Size 2
Board Risk 8
Book Value -0.056
City Chicago
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 10.2
Current Ratio 1.449
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 10.5
Day Low 10.15
Display Name Xeris Biopharma
Dividend Yield 0.0
Earnings Call Timestamp End 1,786,019,400
Earnings Call Timestamp Start 1,786,019,400
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda 48,769,000
Ebitda Margins 0.1454
Enterprise To Ebitda 42.543
Enterprise To Revenue 6.186
Enterprise Value 2,074,765,440
Eps Current Year -0.01667
Eps Forward 0.37
Eps Trailing Twelve Months -0.1
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 8.6934
Fifty Day Average Change 1.5065994
Fifty Day Average Change Percent 0.17330381
Fifty Two Week Change Percent 28.817738
Fifty Two Week High 11.33
Fifty Two Week High Change -1.1300001
Fifty Two Week High Change Percent -0.09973523
Fifty Two Week Low 5.25
Fifty Two Week Low Change 4.95
Fifty Two Week Low Change Percent 0.9428571
Fifty Two Week Range 5.25 - 11.33
Financial Currency USD
First Trade Date Milliseconds 1,529,587,800,000
Float Shares 176,066,720
Forward Eps 0.37
Forward P E 27.567566
Free Cashflow 52,450,124
Full Exchange Name NasdaqGS
Full Time Employees 435
Fullday Change -0.27999973
Fullday Change Percent -2.6768618
Fullday Price 10.18
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.86574996
Gross Profits 290,384,992
Has Pre Post Market Data 1
Held Percent Insiders 0.03029
Held Percent Institutions 0.60699004
Implied Shares Outstanding 182,320,306
Industry Drug Manufacturers - Specialty & Generic
Industry Disp Drug Manufacturers - Specialty & Generic
Industry Key drug-manufacturers-specialty-generic
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.
Long Name Xeris Biopharma Holdings, Inc.
Market us_market
Market Cap 1,859,667,072
Market State POST
Max Age 86,400
Message Board Id finmb_105901792
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-10-13
Net Income To Common -17,165,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,579,805,451
Number Of Analyst Opinions 7
Open 10.41
Operating Cashflow 56,608,000
Operating Margins 0.05617
Overall Risk 8
Payout Ratio 0.0
Phone 844 445 5704
Post Market Change -0.019999504
Post Market Change Percent -0.19607358
Post Market Price 10.18
Post Market Time 1,791,922,907
Prev Name Xeris Pharmaceuticals, Inc.
Previous Close 10.46
Price Eps Current Year -611.8776
Price Hint 2
Price To Book -182.14285
Price To Sales Trailing12 Months 5.544393
Profit Margins -0.05118
Quick Ratio 0.949
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.42857
Region US
Regular Market Change -0.26000023
Regular Market Change Percent -2.4856617
Regular Market Day High 10.5
Regular Market Day Low 10.15
Regular Market Day Range 10.15 - 10.5
Regular Market Open 10.41
Regular Market Previous Close 10.46
Regular Market Price 10.2
Regular Market Time 1,791,921,600
Regular Market Volume 2,217,267
Return On Assets 0.06127
Revenue Growth 0.287
Revenue Per Share 1.993
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 182,320,306
Shares Percent Shares Out 0.0395
Shares Short 7,202,379
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 8,041,258
Short Name Xeris Biopharma Holdings, Inc.
Short Percent Of Float 0.040799998
Short Ratio 2.45
Source Interval 15
State IL
Symbol XERS
Target High Price 18.0
Target Low Price 8.0
Target Mean Price 12.85714
Target Median Price 12.0
Total Cash 121,747,000
Total Cash Per Share 0.668
Total Debt 289,441,984
Total Revenue 335,414,016
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.1
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 7.28945
Two Hundred Day Average Change 2.9105496
Two Hundred Day Average Change Percent 0.39928246
Type Disp Equity
Volume 2,217,267
Website https://www.xerispharma.com
Zip 60,607