Xeris Biopharma Holdings, Inc. (XERS)Healthcare | Drug Manufacturers - Specialty & Generic | Chicago, United States | NasdaqGS
8.48 USD
-0.12
(-1.395%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 8.48 |
Hot Take ↕ | Aug. 22, 2026, 5:20 a.m. EDT
The investment case here is a classic turnaround story where the market has priced in a disaster, yet the operational reality suggests a recovery is underway. Fundamentally, the company is showing signs of life with revenue growing nearly 29% year-over-year and gross margins expanding to 86.6%. Crucially, the multi-year price trajectory tells a different story than the headline numbers; despite four years of losses, the stock has surged 176% in the trailing twelve months, erasing a massive portion of its historical decline. This suggests the market is finally recognizing the value of their extended exclusivity on Keveyis and the recent patent wins. However, the path forward remains precarious. The balance sheet is fragile, with debt nearly double the cash on hand, and the company is still burning cash, evidenced by negative profit margins. While the recent price action shows strong momentum—trading well above its 50-day and 200-day averages—the statistical forecasting models are currently weak and leaning slightly negative, likely reflecting the high volatility and uncertainty surrounding biotech trials. The options market is screaming 'upside,' with no hedging activity visible, which aligns with the bullish sentiment but adds significant tail risk if the next catalyst misses expectations. For a patient investor willing to tolerate the binary nature of biotech, the valuation appears attractive relative to the growth rate, but the lack of a dividend and the thin balance sheet mean this is strictly a growth play, not a value hold. |
| Model | MAE |
|---|---|
| MSTL ✓ | 0.256471 |
| AutoTheta | 0.267916 |
| AutoETS | 0.268823 |
| AutoARIMA | 0.274825 |
Forecast horizon: 45 days | Selected: MSTL
| Forecast Reliability | |
|---|---|
| Score | 42% |
| H-stat | 5.30 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.093 |
| Excess Kurtosis | -0.62 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Revenue per Share | 1.993 |
| Market Cap | 1,546,076,032 |
| Forward P/E | 21.74 |
| Beta | 0.85 |
| Profit Margins | -5.12% |
| Previous Name | Xeris Pharmaceuticals, Inc. |
| Website | https://www.xerispharma.com |
As of Aug. 22, 2026, 5:20 a.m. EDT: Speculators are overwhelmingly bullish, with open interest concentrated entirely in out-of-the-money calls across all expirations. There is zero put volume recorded, indicating a complete absence of hedging or bearish positioning. Call open interest peaks significantly at the $10 strike, suggesting a collective expectation of a move toward or above that level within the next few months.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.08585858 |
| Address1 | 1,375 West Fulton Street |
| Address2 | Suite 1300 |
| All Time High | 27.98 |
| All Time Low | 0.97 |
| Ask | 10.75 |
| Ask Size | 2 |
| Audit Risk | 5 |
| Average Analyst Rating | 1.4 - Strong Buy |
| Average Daily Volume10 Day | 1,531,120 |
| Average Daily Volume3 Month | 1,888,279 |
| Average Volume | 1,888,279 |
| Average Volume10Days | 1,531,120 |
| Beta | 0.852 |
| Bid | 7.61 |
| Bid Size | 3 |
| Board Risk | 8 |
| Book Value | -0.056 |
| City | Chicago |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 8 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 8.48 |
| Current Ratio | 1.449 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 8.675 |
| Day Low | 8.375 |
| Display Name | Xeris Biopharma |
| Earnings Call Timestamp End | 1,786,019,400 |
| Earnings Call Timestamp Start | 1,786,019,400 |
| Earnings Timestamp | 1,786,019,400 |
| Earnings Timestamp End | 1,793,881,800 |
| Earnings Timestamp Start | 1,793,881,800 |
| Ebitda | 48,769,000 |
| Ebitda Margins | 0.1454 |
| Enterprise To Ebitda | 35.141 |
| Enterprise To Revenue | 5.109 |
| Enterprise Value | 1,713,771,136 |
| Eps Current Year | -0.00333 |
| Eps Forward | 0.39 |
| Eps Trailing Twelve Months | -0.1 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 8.23 |
| Fifty Day Average Change | 0.25 |
| Fifty Day Average Change Percent | 0.030376673 |
| Fifty Two Week Change Percent | 8.585858 |
| Fifty Two Week High | 10.08 |
| Fifty Two Week High Change | -1.6000004 |
| Fifty Two Week High Change Percent | -0.1587302 |
| Fifty Two Week Low | 5.25 |
| Fifty Two Week Low Change | 3.2299995 |
| Fifty Two Week Low Change Percent | 0.615238 |
| Fifty Two Week Range | 5.25 - 10.08 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,529,587,800,000 |
| Float Shares | 175,948,211 |
| Forward Eps | 0.39 |
| Forward P E | 21.74359 |
| Free Cashflow | 52,450,124 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 435 |
| Fullday Change | -0.120001 |
| Fullday Change Percent | -1.39536 |
| Fullday Price | 8.48 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,785,542,400 |
| Gross Margins | 0.86574996 |
| Gross Profits | 290,384,992 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.03083 |
| Held Percent Institutions | 0.59956 |
| Implied Shares Outstanding | 182,320,306 |
| Industry | Drug Manufacturers - Specialty & Generic |
| Industry Disp | Drug Manufacturers - Specialty & Generic |
| Industry Key | drug-manufacturers-specialty-generic |
| Is Earnings Date Estimate | 0 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois. |
| Long Name | Xeris Biopharma Holdings, Inc. |
| Market | us_market |
| Market Cap | 1,546,076,032 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_105901792 |
| Most Recent Quarter | 1,782,777,600 |
| Name Change Date | 2,026-08-28 |
| Net Income To Common | -17,165,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,567,954,631 |
| Number Of Analyst Opinions | 7 |
| Open | 8.61 |
| Operating Cashflow | 56,608,000 |
| Operating Margins | 0.05617 |
| Overall Risk | 8 |
| Payout Ratio | 0.0 |
| Phone | 844 445 5704 |
| Post Market Change | 0.0 |
| Post Market Change Percent | 0.0 |
| Post Market Price | 8.48 |
| Post Market Time | 1,787,959,804 |
| Prev Name | Xeris Pharmaceuticals, Inc. |
| Previous Close | 8.6 |
| Price Eps Current Year | -2,546.5464 |
| Price Hint | 2 |
| Price To Book | -151.42856 |
| Price To Sales Trailing12 Months | 4.6094556 |
| Profit Margins | -0.05118 |
| Quick Ratio | 0.949 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.42857 |
| Region | US |
| Regular Market Change | -0.120001 |
| Regular Market Change Percent | -1.39536 |
| Regular Market Day High | 8.675 |
| Regular Market Day Low | 8.375 |
| Regular Market Day Range | 8.375 - 8.675 |
| Regular Market Open | 8.61 |
| Regular Market Previous Close | 8.6 |
| Regular Market Price | 8.48 |
| Regular Market Time | 1,787,947,201 |
| Regular Market Volume | 1,027,270 |
| Return On Assets | 0.06127 |
| Revenue Growth | 0.287 |
| Revenue Per Share | 1.993 |
| Sand P52 Week Change | 0.20504117 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 182,320,306 |
| Shares Percent Shares Out | 0.0479 |
| Shares Short | 8,728,856 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 10,078,469 |
| Short Name | Xeris Biopharma Holdings, Inc. |
| Short Percent Of Float | 0.0494 |
| Short Ratio | 5.33 |
| Source Interval | 15 |
| State | IL |
| Symbol | XERS |
| Target High Price | 18.0 |
| Target Low Price | 8.0 |
| Target Mean Price | 11.71429 |
| Target Median Price | 12.0 |
| Total Cash | 121,747,000 |
| Total Cash Per Share | 0.668 |
| Total Debt | 289,441,984 |
| Total Revenue | 335,414,016 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -0.1 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 7.01115 |
| Two Hundred Day Average Change | 1.4688497 |
| Two Hundred Day Average Change Percent | 0.20950197 |
| Type Disp | Equity |
| Volume | 1,027,270 |
| Website | https://www.xerispharma.com |
| Zip | 60,607 |