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Xenon Pharmaceuticals Inc. (XENE)

Healthcare | Biotechnology | Burnaby, Canada | NasdaqGM
67.72 USD -1.20 (-1.741%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★★★☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5:40 a.m. EDT

The immediate outlook is driven by a powerful convergence of positive clinical catalysts and aggressive speculative positioning. Recent headlines regarding epilepsy trial progress and a 40% surge on data suggest the market is re-rating the company's core assets, while the options chain confirms this with a distinct bullish bias where traders are betting on a move toward the $75-$80 range. However, this optimism sits atop a precarious fundamental foundation: the company is burning significant cash with negative free cash flow and no revenue, resulting in a negative forward P/E. While the balance sheet currently appears robust relative to debt, the lack of commercial traction means this is purely a binary event-driven play. The long-term investment case remains neutral due to the absence of a proven revenue engine and the inherent risks of late-stage biotech development, making this a high-risk, high-reward trade dependent on upcoming data readouts rather than a sustainable business model.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.033163
AutoARIMA0.033395
MSTL0.034558
AutoTheta0.071705

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 37%
H-stat 2.80
Ljung-Box p 0.000
Jarque-Bera p 0.227
Excess Kurtosis -0.13
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.56
Market Cap 6,546,191,360
Forward P/E -13.52
Beta 0.61
Website https://www.xenon-pharma.com

As of July 11, 2026, 5:40 a.m. EDT: Speculators are aggressively positioning for upside, evidenced by heavy open interest concentration in out-of-the-money calls at strikes 75 and 80 for near-term expirations. The call volume-to-open-interest ratio is significantly elevated at the 75 strike, indicating active buying rather than passive hedging. Conversely, put activity is sparse and concentrated deep in-the-money, suggesting limited defensive positioning compared to the bullish call skew. Implied volatility remains elevated for near-term strikes, pricing in continued uncertainty around clinical milestones.


Info Dump

Attribute Value
52 Week Change 1.1141105
Address1 200-3650 Gilmore Way
All Time High 72.66
All Time Low 2.1
Ask 84.99
Ask Size 2
Audit Risk 5
Average Daily Volume10 Day 2,658,000
Average Daily Volume3 Month 1,423,314
Average Volume 1,423,314
Average Volume10Days 2,658,000
Beta 0.613
Bid 47.88
Bid Size 2
Board Risk 1
Book Value 7.271
City Burnaby
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country Canada
Crypto Tradeable 0
Currency USD
Current Price 67.72
Current Ratio 27.794
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 67.87
Day Low 65.5301
Debt To Equity 0.56
Display Name Xenon Pharmaceuticals
Earnings Call Timestamp End 1,778,185,800
Earnings Call Timestamp Start 1,778,185,800
Earnings Timestamp 1,778,184,000
Earnings Timestamp End 1,778,184,000
Earnings Timestamp Start 1,778,184,000
Ebitda -410,188,992
Ebitda Margins 0.0
Enterprise To Ebitda -13.308
Enterprise Value 5,458,935,296
Eps Current Year -4.81031
Eps Forward -5.00938
Eps Trailing Twelve Months -4.7
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 56.205
Fifty Day Average Change 11.514999
Fifty Day Average Change Percent 0.20487499
Fifty Two Week Change Percent 111.41105
Fifty Two Week High 72.66
Fifty Two Week High Change -4.9400024
Fifty Two Week High Change Percent -0.06798792
Fifty Two Week Low 30.0
Fifty Two Week Low Change 37.72
Fifty Two Week Low Change Percent 1.2573334
Fifty Two Week Range 30.0 - 72.66
Financial Currency USD
First Trade Date Milliseconds 1,415,197,800,000
Float Shares 90,758,318
Forward Eps -5.00938
Forward P E -13.51864
Free Cashflow -186,274,496
Full Exchange Name NasdaqGM
Full Time Employees 358
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Gross Profits -328,246,016
Has Pre Post Market Data 1
Held Percent Insiders 0.00125
Held Percent Institutions 1.07512
Implied Shares Outstanding 96,665,550
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders. Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression. In addition, the company's Phase 1 Single Ascending Dose/Multiple Ascending Dose products include XEN1701 targeting the sodium channel and XEN1120 targeting the Kv7 potassium channel for the treatment of pain. The company has a license and collaboration agreement with Neurocrine Biosciences, Inc. for the development of NBI-921355, a Nav1.2/1.6 sodium channel inhibitor that is in Phase 1 clinical trials for the treatment of certain types of epilepsy. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.
Long Name Xenon Pharmaceuticals Inc.
Market us_market
Market Cap 6,546,191,360
Market State PRE
Max Age 86,400
Message Board Id finmb_565718
Most Recent Quarter 1,774,915,200
Net Income To Common -383,164,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 6,662,189,706
Number Of Analyst Opinions 19
Open 67.79
Operating Cashflow -306,363,008
Operating Margins 0.0
Overall Risk 4
Payout Ratio 0.0
Phone 604 484 3300
Pre Market Change 0.12999725
Pre Market Change Percent 0.19196287
Pre Market Price 67.85
Pre Market Time 1,784,023,130
Previous Close 68.92
Price Eps Current Year -14.078095
Price Hint 2
Price To Book 9.313712
Price To Sales Trailing12 Months Infinity
Profit Margins 0.0
Quick Ratio 27.525
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -1.2
Regular Market Change Percent -1.74114
Regular Market Day High 67.87
Regular Market Day Low 65.5301
Regular Market Day Range 65.5301 - 67.87
Regular Market Open 67.79
Regular Market Previous Close 68.92
Regular Market Price 67.72
Regular Market Time 1,783,972,800
Regular Market Volume 1,527,396
Return On Assets -0.24215999
Return On Equity -0.37533
Revenue Per Share 0.0
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 96,665,550
Shares Percent Shares Out 0.0647
Shares Short 6,257,737
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 4,044,948
Short Name Xenon Pharmaceuticals Inc.
Short Percent Of Float 0.0648
Short Ratio 3.56
Source Interval 15
State BC
Symbol XENE
Target High Price 100.0
Target Low Price 63.0
Target Mean Price 80.56053
Target Median Price 80.0
Total Cash 1,094,747,008
Total Cash Per Share 11.325
Total Debt 7,491,000
Total Revenue 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.7
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 48.117523
Two Hundred Day Average Change 19.602478
Two Hundred Day Average Change Percent 0.40738752
Type Disp Equity
Volume 1,527,396
Website https://www.xenon-pharma.com
Zip V5G 4W8