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Xenon Pharmaceuticals Inc. (XENE)

Healthcare | Biotechnology | Burnaby, Canada | NasdaqGM
59.70 USD +1.27 (2.174%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 59.50 -0.20 (-0.200%) ⇩ (April 17, 2026, 5:41 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:12 p.m. EDT

Despite distressing fundamentals characterized by negative earnings, high cash burn, and low revenue, XENE is exhibiting strong speculative momentum driven by positive epilepsy trial data and a massive upcoming equity offering. The options flow confirms a 'smart money' positioning targeting a move toward the $70–$75 range before year-end, turning this into a momentum play despite the invalidity of traditional valuation metrics.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.159356
MSTL0.167369
AutoARIMA0.168916
AutoETS0.169426

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 40%
H-stat 163.20
Ljung-Box p 0.000
Jarque-Bera p 0.049
Excess Kurtosis -1.79
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.366
Revenue per Share 0.095
Market Cap 5,697,001,472
Forward P/E -12.62
Beta 0.75
Website https://www.xenon-pharma.com

As of April 18, 2026, 11:12 p.m. EDT: Options activity reveals a distinct bullish skew. Call volume and Open Interest are heavily concentrated at strikes 70 and 75 for July expiration, with significant 'New Flow' at the $60 ATM strike in the near term. Put activity is sparse and primarily limited to lower strikes ($50) compared to the depth of call positioning, suggesting a bullish price/target expectation close to $65-$70 within the next two months. Implied volatility for calls is relatively contained (0.51-0.61 ATM) compared to the elevated 0.77 ATM IV for puts, indicating market pricing of downside protection is more expensive than upside speculation at this moment.


Info Dump

Attribute Value
52 Week Change 0.72046113
Address1 200-3650 Gilmore Way
All Time High 63.95
All Time Low 2.1
Ask 76.16
Ask Size 2
Audit Risk 5
Average Daily Volume10 Day 869,450
Average Daily Volume3 Month 1,368,372
Average Volume 1,368,372
Average Volume10Days 869,450
Beta 0.745
Bid 42.64
Bid Size 2
Board Risk 2
Book Value 7.271
City Burnaby
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 7
Country Canada
Crypto Tradeable 0
Currency USD
Current Price 59.7
Current Ratio 13.415
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 59.82
Day Low 58.6483
Debt To Equity 1.366
Display Name Xenon Pharmaceuticals
Earnings Call Timestamp End 1,762,205,400
Earnings Call Timestamp Start 1,762,205,400
Earnings Timestamp 1,772,139,600
Earnings Timestamp End 1,778,529,600
Earnings Timestamp Start 1,778,529,600
Ebitda -370,527,008
Ebitda Margins 0.0
Enterprise To Ebitda -11.944
Enterprise To Revenue 590.069
Enterprise Value 4,425,519,616
Eps Current Year -4.82655
Eps Forward -4.73106
Eps Trailing Twelve Months -4.36
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 51.0193
Fifty Day Average Change 8.680702
Fifty Day Average Change Percent 0.17014547
Fifty Two Week Change Percent 72.04611
Fifty Two Week High 63.95
Fifty Two Week High Change -4.25
Fifty Two Week High Change Percent -0.06645817
Fifty Two Week Low 28.19
Fifty Two Week Low Change 31.51
Fifty Two Week Low Change Percent 1.1177722
Fifty Two Week Range 28.19 - 63.95
Financial Currency USD
First Trade Date Milliseconds 1,415,197,800,000
Float Shares 78,362,782
Forward Eps -4.73106
Forward P E -12.618736
Free Cashflow -175,082,752
Full Exchange Name NasdaqGM
Full Time Employees 358
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Gross Profits -293,438,016
Has Pre Post Market Data 1
Held Percent Insiders 0.00115
Held Percent Institutions 0.95317
Implied Shares Outstanding 95,427,159
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders. Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression. In addition, the company's Phase 1 Single Ascending Dose/Multiple Ascending Dose products include XEN1701 targeting the sodium channel and XEN1120 targeting the Kv7 potassium channel for the treatment of pain. The company has a license and collaboration agreement with Neurocrine Biosciences, Inc. for the development of NBI-921355, a Nav1.2/1.6 sodium channel inhibitor that is in Phase 1 clinical trials for the treatment of certain types of epilepsy. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.
Long Name Xenon Pharmaceuticals Inc.
Market us_market
Market Cap 5,697,001,472
Market State PREPRE
Max Age 86,400
Message Board Id finmb_565718
Most Recent Quarter 1,767,139,200
Net Income To Common -345,910,016
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,695,092,849
Number Of Analyst Opinions 19
Open 59.47
Operating Cashflow -279,118,016
Operating Margins -49.742672
Overall Risk 3
Payout Ratio 0.0
Phone 604 484 3300
Post Market Change -0.20000076
Post Market Change Percent -0.33500963
Post Market Price 59.5
Post Market Time 1,776,462,115
Previous Close 58.43
Price Eps Current Year -12.369083
Price Hint 2
Price To Book 8.2107
Price To Sales Trailing12 Months 759.6002
Profit Margins 0.0
Quick Ratio 13.167
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 1.27
Regular Market Change Percent 2.17354
Regular Market Day High 59.82
Regular Market Day Low 58.6483
Regular Market Day Range 58.6483 - 59.82
Regular Market Open 59.47
Regular Market Previous Close 58.43
Regular Market Price 59.7
Regular Market Time 1,776,456,000
Regular Market Volume 844,098
Return On Assets -0.32581002
Return On Equity -0.51757
Revenue Per Share 0.095
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 95,427,159
Shares Percent Shares Out 0.0508
Shares Short 4,851,044
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 5,533,096
Short Name Xenon Pharmaceuticals Inc.
Short Percent Of Float 0.0555
Short Ratio 2.13
Source Interval 15
State BC
Symbol XENE
Target High Price 100.0
Target Low Price 58.58
Target Mean Price 79.24105
Target Median Price 80.0
Total Cash 548,886,016
Total Cash Per Share 6.598
Total Debt 7,944,000
Total Revenue 7,500,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.36
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 42.090473
Two Hundred Day Average Change 17.609528
Two Hundred Day Average Change Percent 0.41837323
Type Disp Equity
Volume 844,098
Website https://www.xenon-pharma.com
Zip V5G 4W8