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Xenetic Biosciences, Inc. (XBIO)

Healthcare | Biotechnology | Framingham, United States | NasdaqCM
2.01 USD -0.09 (-4.286%) ⇩ (Oct. 15, 2026, 4 p.m. EDT)

Short-term:★☆☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 9:41 a.m. EDT

The immediate outlook is severely clouded by a relentless downward price trend over the last two months, where the stock has shed nearly 17% of its value, moving from mid-September highs around $2.57 down to the current $2.13. This technical weakness coincides with a massive structural failure in the company's history: over the past nine years, the investment has lost 98.84% of its value. Although the most recent annual report shows a rebound, the market has punished the business repeatedly, leaving it with negative earnings, negative free cash flow, and a negative operating margin. There is no dividend to provide income, and the balance sheet, while showing high liquidity ratios, cannot offset the reality of a biotech firm burning cash without profitability. The statistical forecast offers a negligible upward lean, but it is too weak to counteract the overwhelming evidence of deteriorating performance and a multi-year decline in shareholder value.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.208777
AutoARIMA0.209204
AutoETS0.209682
AutoTheta0.216691

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 32%
H-stat 16.23
Ljung-Box p 0.000
Jarque-Bera p 0.253
Excess Kurtosis -1.21
Attribute Value
Sector Healthcare
Revenue per Share 1.57
Market Cap 4,709,794
Forward P/E -3.05
Beta 2.20
Profit Margins -75.91%
Website https://www.xeneticbio.com

Info Dump

Attribute Value
52 Week Change -0.52164006
Address1 945 Concord Street
All Time High 1,074.0
All Time Low 1.87
Ask 2.86
Ask Size 2
Average Daily Volume10 Day 17,520
Average Daily Volume3 Month 87,409
Average Volume 87,409
Average Volume10Days 17,520
Beta 2.202
Bid 1.59
Bid Size 2
Book Value 2.592
City Framingham
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.01
Current Ratio 7.435
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 2.09
Day Low 1.885
Display Name Xenetic Biosciences
Dividend Date 1,561,420,800
Dividend Yield 0.0
Earnings Timestamp End 1,755,288,000
Earnings Timestamp Start 1,754,942,400
Ebitda Margins 0.0
Enterprise To Revenue -0.54
Enterprise Value -1,761,972
Eps Forward -0.66
Eps Trailing Twelve Months -1.14
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.1467
Fifty Day Average Change -1.1366999
Fifty Day Average Change Percent -0.36123556
Fifty Two Week Change Percent -52.164005
Fifty Two Week High 4.939
Fifty Two Week High Change -2.9290001
Fifty Two Week High Change Percent -0.59303504
Fifty Two Week Low 1.87
Fifty Two Week Low Change 0.13999999
Fifty Two Week Low Change Percent 0.0748663
Fifty Two Week Range 1.87 - 4.939
Financial Currency USD
First Trade Date Milliseconds 1,467,293,400,000
Float Shares 1,891,088
Forward Eps -0.66
Forward P E -3.0454545
Free Cashflow -1,174,761
Full Exchange Name NasdaqCM
Full Time Employees 2
Fullday Change -0.089999914
Fullday Change Percent -4.3062162
Fullday Price 2.01
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 3,260,777
Has Pre Post Market Data 1
Held Percent Insiders 0.114300005
Held Percent Institutions 0.06491
Implied Shares Outstanding 2,343,181
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,684,108,800
Last Split Factor 1:10
Long Business Summary Xenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing immune-oncology technologies to treat cancers. Its DNase technology targets neutrophil extracellular traps (NETS), which are involved in cancer growth, metastasis, and progression, and contribute to immunotherapy, chemotherapy, and radiotherapy resistance. The company's product pipeline includes XBIO-015 for the treatment of pancreatic carcinoma and solid tumors; XBIO-020 for the treatment of solid tumors; and ErepoXen, which uses PolyXen platform technology for the treatment of anemia in chronic kidney disease (CKD) patients. It has a sublicensing agreement with Takeda Pharmaceutical Co. Ltd, as well as various research, development, license and supply agreements with Serum Institute of India, PJSC Pharmsynthez, and SynBio, LLC. Xenetic Biosciences, Inc. is headquartered in Framingham, Massachusetts.
Long Name Xenetic Biosciences, Inc.
Market us_market
Market Cap 4,709,794
Market State POST
Max Age 86,400
Message Board Id finmb_23143993
Most Recent Quarter 1,782,777,600
Net Income To Common -2,475,093
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,857,952
Open 2.09
Operating Cashflow -2,312,795
Operating Margins -1.47092
Payout Ratio 0.0
Phone 781 778 7720
Previous Close 2.1
Price Hint 4
Price To Book 0.775463
Price To Sales Trailing12 Months 1.4443778
Profit Margins -0.75905
Quick Ratio 7.231
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.089999914
Regular Market Change Percent -4.2857103
Regular Market Day High 2.09
Regular Market Day Low 1.885
Regular Market Day Range 1.885 - 2.09
Regular Market Open 2.09
Regular Market Previous Close 2.1
Regular Market Price 2.01
Regular Market Time 1,792,094,400
Regular Market Volume 51,377
Return On Assets -0.26798
Return On Equity -0.4704
Revenue Growth 0.12
Revenue Per Share 1.57
Sand P52 Week Change 0.16440773
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 2,343,181
Shares Percent Shares Out 0.0055
Shares Short 12,868
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 20,320
Short Name Xenetic Biosciences, Inc.
Short Percent Of Float 0.0057
Short Ratio 0.08
Source Interval 15
State MA
Symbol XBIO
Total Cash 6,471,766
Total Cash Per Share 2.762
Total Debt 0
Total Revenue 3,260,777
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.14
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.85528
Two Hundred Day Average Change -0.84527993
Two Hundred Day Average Change Percent -0.296041
Type Disp Equity
Volume 51,377
Website https://www.xeneticbio.com
Zip 1,701