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Wave Life Sciences Ltd. (WVE)

Healthcare | Biotechnology | Singapore, Singapore | NasdaqGM
7.56 USD -0.02 (-0.264%) ⇩ (April 21, 2026, 10:32 a.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 12:19 a.m. EDT

WVE is a textbook 'biotech squeeze' play where fundamental risk (negative EPS, -79% revenue growth) creates a tailwind for contrarian speculation. The analyst consensus is a strong buy (mean price $24.93) based on pipeline news (Delaware move), which has already spliced sentiment into the price. However, the stock is trading 34% below its 50-day moving average, a powerful technical signal that limits downside. For the quantist, the delta-neutral thesis holds: buy the dividend stream of the turnaround story while the short interest expires. The upcoming earnings date will likely recap the 'Shell Shock' data, which could act as a catalyst for the $15 Call strike target if the data holds.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.211456
AutoETS0.216802
AutoARIMA0.216803
AutoTheta0.229621

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 31%
H-stat 108.80
Ljung-Box p 0.000
Jarque-Bera p 0.026
Excess Kurtosis -1.06
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.376
Revenue per Share 0.253
Market Cap 1,423,207,424
Forward P/E -5.65
Beta -1.32
Website https://wavelifesciences.com

As of April 19, 2026, 12:19 a.m. EDT: Options market shows bullish conviction with heavy Call volume/flow at strikes $15.00 and $16.00 w/ massive OI (9.9k-17.6k), acting as aggressive directional targets. Put activity is significantly higher premiums-wise than calls, suggesting premium sellers or protection for downside below current levels, but the Call volume is dominant. The $15.00 Call strike shows a massive disproportion (+100% vol), indicating speculative buyers believe a 50%+ move is possible. However, deep OTM put volume (-86.6% distribution) exists at $1.00, implying a 'crash' strategy or insurance. Overall, the structure favors upside if $11.31 (50-day avg) support holds.


Info Dump

Attribute Value
52 Week Change 0.15548778
Address1 Marina One East Tower
Address2 7 Straits View No.12-00
All Time High 56.0
All Time Low 1.16
Ask 9.65
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 3,471,620
Average Daily Volume3 Month 4,218,213
Average Volume 4,218,213
Average Volume10Days 3,471,620
Beta -1.32
Bid 5.42
Bid Size 2
Board Risk 3
Book Value 2.762
City Singapore
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 7
Country Singapore
Crypto Tradeable 0
Currency USD
Current Price 7.56
Current Ratio 6.467
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 7.61
Day Low 7.46
Debt To Equity 3.376
Display Name Wave Life Sciences
Earnings Call Timestamp End 1,772,112,600
Earnings Call Timestamp Start 1,772,112,600
Earnings Timestamp 1,772,112,600
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -211,943,008
Ebitda Margins 0.0
Enterprise To Ebitda -4.013
Enterprise To Revenue 19.906
Enterprise Value 850,544,576
Eps Current Year -1.30977
Eps Forward -1.33903
Eps Trailing Twelve Months -1.21
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 11.0992
Fifty Day Average Change -3.5392003
Fifty Day Average Change Percent -0.31886986
Fifty Two Week Change Percent 15.548778
Fifty Two Week High 21.73
Fifty Two Week High Change -14.17
Fifty Two Week High Change Percent -0.6520939
Fifty Two Week Low 5.02
Fifty Two Week Low Change 2.54
Fifty Two Week Low Change Percent 0.5059761
Fifty Two Week Range 5.02 - 21.73
Financial Currency USD
First Trade Date Milliseconds 1,447,252,200,000
Float Shares 122,772,351
Forward Eps -1.33903
Forward P E -5.645878
Free Cashflow -112,548,376
Full Exchange Name NasdaqGM
Full Time Employees 317
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Gross Profits -140,052,000
Has Pre Post Market Data 1
Held Percent Insiders 0.14205
Held Percent Institutions 0.93586
Implied Shares Outstanding 188,254,954
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company's medicines platform, PRISM combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated small interfering RNA designed to silence INHBE mRNA targeting obesity; WVE-008, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of liver disease; WVE-N531, an exon splicing oligonucleotide for the treatment of Duchenne muscular dystrophy; and WVE-003, an allele-selective oligonucleotide for the treatment of Huntington's disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was founded in 2012 and is based in Singapore.
Long Name Wave Life Sciences Ltd.
Market us_market
Market Cap 1,423,207,424
Market State REGULAR
Max Age 86,400
Message Board Id finmb_256557334
Most Recent Quarter 1,767,139,200
Net Income To Common -204,378,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,426,031,276
Number Of Analyst Opinions 15
Open 7.54
Operating Cashflow -187,492,992
Operating Margins -3.2744
Overall Risk 4
Payout Ratio 0.0
Phone 65 6236 3388
Previous Close 7.58
Price Eps Current Year -5.7720056
Price Hint 2
Price To Book 2.7371469
Price To Sales Trailing12 Months 33.309322
Profit Margins 0.0
Quick Ratio 6.347
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.125
Region US
Regular Market Change -0.01999998
Regular Market Change Percent -0.263852
Regular Market Day High 7.61
Regular Market Day Low 7.46
Regular Market Day Range 7.46 - 7.61
Regular Market Open 7.54
Regular Market Previous Close 7.58
Regular Market Price 7.56
Regular Market Time 1,776,781,929
Regular Market Volume 431,217
Return On Assets -0.27175
Return On Equity -0.54968
Revenue Growth -0.794
Revenue Per Share 0.253
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 188,254,954
Shares Percent Shares Out 0.070199996
Shares Short 13,210,972
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 13,654,126
Short Name Wave Life Sciences Ltd.
Short Percent Of Float 0.09
Short Ratio 2.24
Source Interval 15
Symbol WVE
Target High Price 52.0
Target Low Price 11.0
Target Mean Price 24.93333
Target Median Price 21.0
Total Cash 602,067,968
Total Cash Per Share 3.198
Total Debt 17,766,000
Total Revenue 42,727,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.21
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 10.21955
Two Hundred Day Average Change -2.6595502
Two Hundred Day Average Change Percent -0.26024142
Type Disp Equity
Volume 431,217
Website https://wavelifesciences.com
Zip 18,936