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Wave Life Sciences Ltd. (WVE)

Healthcare | Biotechnology | Singapore, Singapore | NasdaqGM
5.95 USD -0.30 (-4.800%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★⯪☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:39 a.m. EDT

Wave Life Sciences presents a classic value trap scenario where the market has priced out the business entirely due to deteriorating fundamentals. The company is burning cash aggressively, with negative operating cash flow and gross margins, while the stock has lost nearly two-thirds of its value over the last nine years. Despite a recent year-over-year price recovery, the underlying economics remain broken, making this a poor long-term hold. On the short end, the heavy put open interest suggests traders are hedging against further declines rather than betting on a catalyst-driven surge, keeping the immediate outlook muted. With no dividend to provide income and a balance sheet showing significant operational bleed, investors should avoid this security until the path to profitability becomes clear.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.180222
AutoARIMA0.180224
AutoTheta0.185309
MSTL0.199271

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 31%
H-stat 3.35
Ljung-Box p 0.000
Jarque-Bera p 0.178
Excess Kurtosis -0.66
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.071
Revenue per Share 0.403
Market Cap 1,144,793,088
Forward P/E -5.49
Beta -1.30
Profit Margins -255.70%
Website https://wavelifesciences.com

As of July 11, 2026, 2:39 a.m. EDT: Speculators are positioning heavily for downside protection, evidenced by significant put volume and open interest at strikes well below the current price (e.g., $5.00 and $6.00). While there is some call activity at distant strikes ($20-$33), the overwhelming majority of open interest sits in the out-of-the-money put territory, suggesting a bearish bias or a 'buy the dip' strategy rather than a rally expectation.


Info Dump

Attribute Value
52 Week Change -0.20280612
Address1 Marina One East Tower
Address2 7 Straits View No.12-00
All Time High 56.0
All Time Low 1.16
Ask 7.64
Ask Size 2
Audit Risk 5
Average Daily Volume10 Day 3,382,210
Average Daily Volume3 Month 3,838,131
Average Volume 3,838,131
Average Volume10Days 3,382,210
Beta -1.295
Bid 4.47
Bid Size 2
Board Risk 2
Book Value 2.762
City Singapore
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country Singapore
Crypto Tradeable 0
Currency USD
Current Price 5.95
Current Ratio 11.264
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 6.2583
Day Low 5.9
Debt To Equity 3.071
Display Name Wave Life Sciences
Earnings Call Timestamp End 1,777,379,400
Earnings Call Timestamp Start 1,777,379,400
Earnings Timestamp 1,777,379,400
Earnings Timestamp End 1,785,328,200
Earnings Timestamp Start 1,785,328,200
Ebitda -193,471,008
Ebitda Margins -2.69466
Enterprise To Ebitda -3.183
Enterprise To Revenue 8.577
Enterprise Value 615,784,832
Eps Current Year -0.83755
Eps Forward -1.08388
Eps Trailing Twelve Months -1.05
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.3328
Fifty Day Average Change -0.3828001
Fifty Day Average Change Percent -0.060447212
Fifty Two Week Change Percent -20.280611
Fifty Two Week High 21.73
Fifty Two Week High Change -15.78
Fifty Two Week High Change Percent -0.726185
Fifty Two Week Low 5.02
Fifty Two Week Low Change 0.9299998
Fifty Two Week Low Change Percent 0.18525892
Fifty Two Week Range 5.02 - 21.73
Financial Currency USD
First Trade Date Milliseconds 1,447,252,200,000
Float Shares 90,108,857
Forward Eps -1.08388
Forward P E -5.4895377
Free Cashflow -125,723,128
Full Exchange Name NasdaqGM
Full Time Employees 317
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins -1.6407001
Gross Profits -117,799,000
Has Pre Post Market Data 1
Held Percent Insiders 0.15882
Held Percent Institutions 0.82585
Implied Shares Outstanding 192,402,202
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company's medicines platform, PRISM combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated small interfering RNA designed to silence INHBE mRNA targeting obesity; WVE-008, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of liver disease; WVE-N531, an exon splicing oligonucleotide for the treatment of Duchenne muscular dystrophy; and WVE-003, an allele-selective oligonucleotide for the treatment of Huntington's disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was founded in 2012 and is based in Singapore.
Long Name Wave Life Sciences Ltd.
Market us_market
Market Cap 1,144,793,088
Market State PRE
Max Age 86,400
Message Board Id finmb_256557334
Most Recent Quarter 1,774,915,200
Net Income To Common -183,587,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,144,793,101
Number Of Analyst Opinions 16
Open 6.2
Operating Cashflow -184,007,008
Operating Margins -0.81833
Overall Risk 4
Payout Ratio 0.0
Phone 65 6236 3388
Pre Market Change 0.05000019
Pre Market Change Percent 0.84033936
Pre Market Price 6.0
Pre Market Time 1,784,026,298
Previous Close 6.25
Price Eps Current Year -7.1040535
Price Hint 2
Price To Book 2.1542358
Price To Sales Trailing12 Months 15.944637
Profit Margins -2.5569901
Quick Ratio 10.929
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.3
Regular Market Change Percent -4.8
Regular Market Day High 6.2583
Regular Market Day Low 5.9
Regular Market Day Range 5.9 - 6.2583
Regular Market Open 6.2
Regular Market Previous Close 6.25
Regular Market Price 5.95
Regular Market Time 1,783,972,801
Regular Market Volume 2,388,007
Return On Assets -0.28226
Return On Equity -0.53104997
Revenue Growth 3.169
Revenue Per Share 0.403
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 192,402,202
Shares Percent Shares Out 0.1086
Shares Short 20,901,285
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 18,530,652
Short Name Wave Life Sciences Ltd.
Short Percent Of Float 0.1348
Short Ratio 5.97
Source Interval 15
Symbol WVE
Target High Price 43.0
Target Low Price 12.0
Target Mean Price 21.9375
Target Median Price 18.5
Total Cash 544,590,976
Total Cash Per Share 2.831
Total Debt 15,715,000
Total Revenue 71,798,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.05
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 9.70575
Two Hundred Day Average Change -3.7557507
Two Hundred Day Average Change Percent -0.3869614
Type Disp Equity
Volume 2,388,007
Website https://wavelifesciences.com
Zip 18,936