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Wave Life Sciences Ltd. (WVE)

Healthcare | Biotechnology | Singapore, Singapore | NasdaqGM
5.99 USD -0.14 (-2.365%) ⇩ (July 15, 2026, 10:20 a.m. EDT)

Short-term:★⯪☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:39 a.m. EDT

Wave Life Sciences presents a classic value trap scenario where the market has priced out the business entirely due to deteriorating fundamentals. The company is burning cash aggressively, with negative operating cash flow and gross margins, while the stock has lost nearly two-thirds of its value over the last nine years. Despite a recent year-over-year price recovery, the underlying economics remain broken, making this a poor long-term hold. On the short end, the heavy put open interest suggests traders are hedging against further declines rather than betting on a catalyst-driven surge, keeping the immediate outlook muted. With no dividend to provide income and a balance sheet showing significant operational bleed, investors should avoid this security until the path to profitability becomes clear.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.180222
AutoARIMA0.180224
AutoTheta0.185309
MSTL0.199271

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 31%
H-stat 3.35
Ljung-Box p 0.000
Jarque-Bera p 0.178
Excess Kurtosis -0.66
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.071
Revenue per Share 0.403
Market Cap 1,151,527,296
Forward P/E -5.52
Beta -1.30
Profit Margins -255.70%
Website https://wavelifesciences.com

As of July 11, 2026, 2:39 a.m. EDT: Speculators are positioning heavily for downside protection, evidenced by significant put volume and open interest at strikes well below the current price (e.g., $5.00 and $6.00). While there is some call activity at distant strikes ($20-$33), the overwhelming majority of open interest sits in the out-of-the-money put territory, suggesting a bearish bias or a 'buy the dip' strategy rather than a rally expectation.


Info Dump

Attribute Value
52 Week Change -0.21611255
Address1 Marina One East Tower
Address2 7 Straits View No.12-00
All Time High 56.0
All Time Low 1.16
Ask 7.6
Ask Size 2
Audit Risk 5
Average Daily Volume10 Day 2,887,710
Average Daily Volume3 Month 3,752,081
Average Volume 3,752,081
Average Volume10Days 2,887,710
Beta -1.295
Bid 4.38
Bid Size 2
Board Risk 2
Book Value 2.762
City Singapore
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country Singapore
Crypto Tradeable 0
Currency USD
Current Price 5.985
Current Ratio 11.264
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 6.12
Day Low 5.94
Debt To Equity 3.071
Display Name Wave Life Sciences
Earnings Call Timestamp End 1,777,379,400
Earnings Call Timestamp Start 1,777,379,400
Earnings Timestamp 1,777,379,400
Earnings Timestamp End 1,785,328,200
Earnings Timestamp Start 1,785,328,200
Ebitda -193,471,008
Ebitda Margins -2.69466
Enterprise To Ebitda -3.362
Enterprise To Revenue 9.059
Enterprise Value 650,413,248
Eps Current Year -0.83755
Eps Forward -1.08388
Eps Trailing Twelve Months -1.05
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.2922
Fifty Day Average Change -0.30719995
Fifty Day Average Change Percent -0.048822343
Fifty Two Week Change Percent -21.611256
Fifty Two Week High 21.73
Fifty Two Week High Change -15.744999
Fifty Two Week High Change Percent -0.72457427
Fifty Two Week Low 5.02
Fifty Two Week Low Change 0.96500015
Fifty Two Week Low Change Percent 0.1922311
Fifty Two Week Range 5.02 - 21.73
Financial Currency USD
First Trade Date Milliseconds 1,447,252,200,000
Float Shares 90,108,857
Forward Eps -1.08388
Forward P E -5.5218296
Free Cashflow -125,723,128
Full Exchange Name NasdaqGM
Full Time Employees 317
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins -1.6407001
Gross Profits -117,799,000
Has Pre Post Market Data 1
Held Percent Insiders 0.15882
Held Percent Institutions 0.8282
Implied Shares Outstanding 192,402,202
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company's medicines platform, PRISM combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated small interfering RNA designed to silence INHBE mRNA targeting obesity; WVE-008, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of liver disease; WVE-N531, an exon splicing oligonucleotide for the treatment of Duchenne muscular dystrophy; and WVE-003, an allele-selective oligonucleotide for the treatment of Huntington's disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was founded in 2012 and is based in Singapore.
Long Name Wave Life Sciences Ltd.
Market us_market
Market Cap 1,151,527,296
Market State REGULAR
Max Age 86,400
Message Board Id finmb_256557334
Most Recent Quarter 1,774,915,200
Net Income To Common -183,587,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,180,387,509
Number Of Analyst Opinions 16
Open 6.12
Operating Cashflow -184,007,008
Operating Margins -0.81833
Overall Risk 4
Payout Ratio 0.0
Phone 65 6236 3388
Previous Close 6.13
Price Eps Current Year -7.1458426
Price Hint 2
Price To Book 2.166908
Price To Sales Trailing12 Months 16.038431
Profit Margins -2.5569901
Quick Ratio 10.929
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.14499998
Regular Market Change Percent -2.3654156
Regular Market Day High 6.12
Regular Market Day Low 5.94
Regular Market Day Range 5.94 - 6.12
Regular Market Open 6.12
Regular Market Previous Close 6.13
Regular Market Price 5.985
Regular Market Time 1,784,125,200
Regular Market Volume 210,631
Return On Assets -0.28226
Return On Equity -0.53104997
Revenue Growth 3.169
Revenue Per Share 0.403
Sand P52 Week Change 0.2043345
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 192,402,202
Shares Percent Shares Out 0.1086
Shares Short 20,901,285
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 18,530,652
Short Name Wave Life Sciences Ltd.
Short Percent Of Float 0.1348
Short Ratio 5.97
Source Interval 15
Symbol WVE
Target High Price 43.0
Target Low Price 12.0
Target Mean Price 21.9375
Target Median Price 18.5
Total Cash 544,590,976
Total Cash Per Share 2.831
Total Debt 15,715,000
Total Revenue 71,798,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.05
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 9.69835
Two Hundred Day Average Change -3.7133498
Two Hundred Day Average Change Percent -0.3828847
Type Disp Equity
Volume 210,631
Website https://wavelifesciences.com
Zip 18,936