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Vistagen Therapeutics, Inc. (VTGN)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqCM
0.20 USD -0.01 (-6.103%) ⇩ (Oct. 16, 2026, 4 p.m. EDT)
After hours: 0.20

Short-term:★☆☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 6:48 a.m. EDT

The investment case for Vistagen Therapeutics is currently defined by a stark divergence between speculative hope and fundamental reality. While the options chain reveals a crowd betting on a miraculous turnaround—evidenced by heavy call open interest at the $1.00 level—the underlying business metrics tell a different story. The company is burning through cash at an alarming rate, with operating cash flow of -$62 million and free cash flow of -$37 million, while generating negligible revenue. The balance sheet, though currently showing low debt, is propped up by a massive cash reserve that is rapidly depleting against these losses. The stock has already suffered a catastrophic 97% decline over the last decade, erasing nearly all prior gains. Although the most recent annual report shows a slight uptick in price, the trajectory remains deeply distressed. With no dividend to provide income and no clear path to profitability visible in the data, this remains a high-risk speculative vehicle where the odds favor further downside or a binary event-driven recovery, making it unsuitable for traditional investment strategies.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.114037
AutoARIMA0.114038
MSTL0.189409
AutoTheta0.495486

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 21%
H-stat 1.54
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 2.11
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.198
Revenue per Share 0.061
Market Cap 8,875,383
Forward P/E -0.13
Beta 0.33
Website https://www.vistagen.com

As of Oct. 10, 2026, 6:48 a.m. EDT: Options activity is dominated by out-of-the-money calls, with significant open interest concentrated at the $1.00 strike across multiple expirations, suggesting speculative bets on a massive recovery or catalyst-driven breakout. However, this bullish positioning is heavily outweighed by deep in-the-money put volume, particularly at strikes far above the current price (e.g., $3.00 and $2.00), indicating a 'long gamma' hedge or insurance strategy against a continued collapse rather than a belief in immediate upside. The implied volatility skew shows elevated premiums for downside protection relative to the tiny cost of calls, reflecting a market pricing in severe tail risk.


Info Dump

Attribute Value
52 Week Change -0.94814813
Address1 343 Allerton Avenue
All Time High 1,890.0
All Time Low 0.2
Ask 0.3772
Ask Size 2
Average Daily Volume10 Day 1,053,030
Average Daily Volume3 Month 12,336,657
Average Volume 12,336,657
Average Volume10Days 1,053,030
Beta 0.329
Bid 0.248
Bid Size 1
Book Value 0.552
City South San Francisco
Compensation As Of Epoch Date 1,798,675,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.2
Current Ratio 3.066
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 0.2187
Day Low 0.1977
Debt To Equity 3.198
Display Name Vistagen Therapeutics
Dividend Yield 0.0
Earnings Call Timestamp End 1,770,933,600
Earnings Call Timestamp Start 1,770,933,600
Earnings Timestamp 1,786,710,600
Earnings Timestamp End 1,794,486,600
Earnings Timestamp Start 1,794,486,600
Ebitda -69,459,000
Ebitda Margins 0.0
Enterprise To Ebitda 0.318
Enterprise To Revenue -8.825
Enterprise Value -22,071,618
Eps Current Year -1.475
Eps Forward -1.54
Eps Trailing Twelve Months -1.66
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.2552
Fifty Day Average Change -0.055199996
Fifty Day Average Change Percent -0.21630092
Fifty Two Week Change Percent -94.81481
Fifty Two Week High 5.14
Fifty Two Week High Change -4.94
Fifty Two Week High Change Percent -0.96108955
Fifty Two Week Low 0.1977
Fifty Two Week Low Change 0.0023000091
Fifty Two Week Low Change Percent 0.011633835
Fifty Two Week Range 0.1977 - 5.14
Financial Currency USD
First Trade Date Milliseconds 1,308,663,000,000
Float Shares 41,422,740
Forward Eps -1.54
Forward P E -0.12987013
Free Cashflow -36,950,752
Full Exchange Name NasdaqCM
Full Time Employees 41
Fullday Change -0.012999997
Fullday Change Percent -6.103285
Fullday Price 0.2
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 2,501,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00373
Held Percent Institutions 0.31052
Implied Shares Outstanding 44,376,911
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,774,915,200
Last Split Date 1,686,096,000
Last Split Factor 1:30
Long Business Summary Vistagen Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of therapies for neuropsychiatric and neurological disorders. The company's product pipeline includes Fasedienol, an investigational pherine nasal spray that is in Phase III clinical trial for the treatment of anxiety in adults with social anxiety disorder; and Itruvone, an odorless synthetic investigational neuroactive pherine nasal spray, which is in Phase IIa clinical trial to treat major depressive disorder. It also develops refisolone, an odorless and tasteless synthetic investigational pherine nasal spray that is in Phase IIa clinical trial for the treatment of vasomotor symptoms, including hot flashes due to menopause, premenstrual dysphoric disorder, and other women's health disorders; PH15, an investigational pherine nasal spray, which is in Phase IIa clinical trial for the treatment to improve cognitive impairment caused by mental fatigue disorders; PH284, an odorless and tasteless synthetic investigational pherine nasal spray that is in Phase IIa clinical trial to treat loss of appetite associated with chronic disorders, such as cancer cachexia; and AV-101, an oral prodrug that targets N-methyl-D-aspartate receptor in the brain for treating depression and neurological disorders. It has a license and collaboration agreement with AffaMed Therapeutics, Inc. to develop, manufacture, and commercialize fasedienol for multiple anxiety-related disorders. Vistagen Therapeutics, Inc. was founded in 1998 and is headquartered in South San Francisco, California.
Long Name Vistagen Therapeutics, Inc.
Market us_market
Market Cap 8,875,383
Market State CLOSED
Max Age 86,400
Message Board Id finmb_7691787
Most Recent Quarter 1,782,777,600
Net Income To Common -67,620,000
Next Fiscal Year End 1,806,451,200
Non Diluted Market Cap 16,188,697
Number Of Analyst Opinions 2
Open 0.209
Operating Cashflow -62,297,000
Operating Margins -9.04336
Phone 650 577 3600
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 0.2
Post Market Time 1,792,195,032
Previous Close 0.213
Price Eps Current Year -0.13559322
Price Hint 4
Price To Book 0.36231884
Price To Sales Trailing12 Months 3.5487337
Profit Margins 0.0
Quick Ratio 2.835
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.013
Regular Market Change Percent -6.10328
Regular Market Day High 0.2187
Regular Market Day Low 0.1977
Regular Market Day Range 0.1977 - 0.2187
Regular Market Open 0.209
Regular Market Previous Close 0.213
Regular Market Price 0.2
Regular Market Time 1,792,180,800
Regular Market Volume 557,972
Return On Assets -0.8321
Return On Equity -1.66457
Revenue Growth 5.049
Revenue Per Share 0.061
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 44,376,911
Shares Percent Shares Out 0.0845
Shares Short 3,750,912
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 2,126,593
Short Name VistaGen Therapeutics, Inc.
Short Percent Of Float 0.0848
Short Ratio 0.13
Source Interval 15
State CA
Symbol VTGN
Target High Price 1.0
Target Low Price 1.0
Target Mean Price 1.0
Target Median Price 1.0
Total Cash 31,730,000
Total Cash Per Share 0.715
Total Debt 783,000
Total Revenue 2,501,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.66
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.47375
Two Hundred Day Average Change -0.27375
Two Hundred Day Average Change Percent -0.57783645
Type Disp Equity
Volume 557,972
Website https://www.vistagen.com
Zip 94,080