Vistagen Therapeutics, Inc. (VTGN)Healthcare | Biotechnology | South San Francisco, United States | NasdaqCM
0.25 USD
0.00
(-1.595%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 0.25 0.00 (-0.003%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT) |
Hot Take ↕ | Aug. 22, 2026, 4:27 a.m. EDT
The investment case for Vistagen Therapeutics is effectively broken by a confluence of deteriorating fundamentals and existential market skepticism. The company is trapped in a death spiral: it is burning through cash at an alarming rate with negative operating cash flow of -$66 million and free cash flow of -$40 million, while generating virtually no revenue. The balance sheet is fragile, with cash reserves of only $45 million facing a debt load that, combined with the burn rate, creates a precarious runway. Fundamentally, the business has failed to deliver on its growth promises. Over the last nine years, the stock has lost nearly 97% of its value, reflecting a market verdict that the company cannot sustain operations or generate returns. The recent clinical trial results mentioned in the news headlines appear to have triggered a loss of institutional confidence, evidenced by the heavy put writing and the specific investor alert regarding potential false claims. With no dividend to provide a floor and a management team seemingly struggling to navigate regulatory and scientific hurdles, the security offers no margin of safety. The statistical forecast model correctly identifies a negligible expected return, but the fundamental reality is far more dire: this is a distressed biotech asset with a high probability of delisting or bankruptcy if it cannot secure immediate capital or prove a breakthrough. |
| Model | MAE |
|---|---|
| AutoARIMA ✓ | 0.848936 |
| MSTL | 0.902348 |
| AutoETS | 0.907317 |
| AutoTheta | 0.911222 |
Forecast horizon: 45 days | Selected: AutoARIMA
| Forecast Reliability | |
|---|---|
| Score | 18% |
| H-stat | 1.11 |
| Ljung-Box p | 0.005 |
| Jarque-Bera p | 0.000 |
| Excess Kurtosis | 8.73 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 3.198 |
| Revenue per Share | 0.061 |
| Market Cap | 11,222,921 |
| Forward P/E | -0.16 |
| Beta | 0.38 |
| Website | https://www.vistagen.com |
As of Aug. 22, 2026, 4:27 a.m. EDT: Speculators are overwhelmingly positioning for downside protection rather than upside participation. Put open interest significantly exceeds call open interest across all expirations, with deep out-of-the-money puts showing massive volume relative to calls. The concentration of put open interest at strikes far above the current price (e.g., $2.00 vs $0.24) suggests a fear of a catastrophic collapse or a 'long-only' portfolio insurance strategy where investors are betting against the stock's survival. Call activity is minimal and confined to the immediate money range, indicating a lack of speculative bullishness.
| Attribute | Value |
|---|---|
| 52 Week Change | -0.9261364 |
| Address1 | 343 Allerton Avenue |
| All Time High | 1,890.0 |
| All Time Low | 0.2 |
| Ask | 0.3272 |
| Ask Size | 2 |
| Average Analyst Rating | 3.0 - Hold |
| Average Daily Volume10 Day | 843,940 |
| Average Daily Volume3 Month | 4,110,320 |
| Average Volume | 4,110,320 |
| Average Volume10Days | 843,940 |
| Beta | 0.378 |
| Bid | 0.1804 |
| Bid Size | 2 |
| Book Value | 0.552 |
| City | South San Francisco |
| Compensation As Of Epoch Date | 1,798,675,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 0.2529 |
| Current Ratio | 3.066 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 0.2589 |
| Day Low | 0.246 |
| Debt To Equity | 3.198 |
| Display Name | Vistagen Therapeutics |
| Earnings Call Timestamp End | 1,770,933,600 |
| Earnings Call Timestamp Start | 1,770,933,600 |
| Earnings Timestamp | 1,786,710,600 |
| Earnings Timestamp End | 1,794,486,600 |
| Earnings Timestamp Start | 1,794,486,600 |
| Ebitda | -69,459,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | 0.281 |
| Enterprise To Revenue | -7.814 |
| Enterprise Value | -19,542,134 |
| Eps Current Year | -1.45 |
| Eps Forward | -1.54 |
| Eps Trailing Twelve Months | -1.63 |
| Esg Populated | 0 |
| Exchange | NCM |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 0.3172 |
| Fifty Day Average Change | -0.0643 |
| Fifty Day Average Change Percent | -0.20271122 |
| Fifty Two Week Change Percent | -92.61364 |
| Fifty Two Week High | 5.14 |
| Fifty Two Week High Change | -4.8870997 |
| Fifty Two Week High Change Percent | -0.9507976 |
| Fifty Two Week Low | 0.2 |
| Fifty Two Week Low Change | 0.0529 |
| Fifty Two Week Low Change Percent | 0.2645 |
| Fifty Two Week Range | 0.2 - 5.14 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,308,663,000,000 |
| Float Shares | 41,422,740 |
| Forward Eps | -1.54 |
| Forward P E | -0.16422078 |
| Free Cashflow | -36,950,752 |
| Full Exchange Name | NasdaqCM |
| Full Time Employees | 41 |
| Fullday Change | -0.00409999 |
| Fullday Change Percent | -1.59533 |
| Fullday Price | 0.25 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 1.0 |
| Gross Profits | 2,501,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.00373 |
| Held Percent Institutions | 0.31046 |
| Implied Shares Outstanding | 44,376,911 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,774,915,200 |
| Last Split Date | 1,686,096,000 |
| Last Split Factor | 1:30 |
| Long Business Summary | Vistagen Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of therapies for neuropsychiatric and neurological disorders. The company's product pipeline includes Fasedienol, an investigational pherine nasal spray that is in Phase III clinical trial for the treatment of anxiety in adults with social anxiety disorder; and Itruvone, an odorless synthetic investigational neuroactive pherine nasal spray, which is in Phase IIa clinical trial to treat major depressive disorder. It also develops refisolone, an odorless and tasteless synthetic investigational pherine nasal spray that is in Phase IIa clinical trial for the treatment of vasomotor symptoms, including hot flashes due to menopause, premenstrual dysphoric disorder, and other women's health disorders; PH15, an investigational pherine nasal spray, which is in Phase IIa clinical trial for the treatment to improve cognitive impairment caused by mental fatigue disorders; PH284, an odorless and tasteless synthetic investigational pherine nasal spray that is in Phase IIa clinical trial to treat loss of appetite associated with chronic disorders, such as cancer cachexia; and AV-101, an oral prodrug that targets N-methyl-D-aspartate receptor in the brain for treating depression and neurological disorders. It has a license and collaboration agreement with AffaMed Therapeutics, Inc. to develop, manufacture, and commercialize fasedienol for multiple anxiety-related disorders. Vistagen Therapeutics, Inc. was founded in 1998 and is headquartered in South San Francisco, California. |
| Long Name | Vistagen Therapeutics, Inc. |
| Market | us_market |
| Market Cap | 11,222,921 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_7691787 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -67,620,000 |
| Next Fiscal Year End | 1,806,451,200 |
| Non Diluted Market Cap | 11,404,866 |
| Number Of Analyst Opinions | 2 |
| Open | 0.2569 |
| Operating Cashflow | -62,297,000 |
| Operating Margins | -9.04336 |
| Payout Ratio | 0.0 |
| Phone | 650 577 3600 |
| Post Market Change | -0.0029000044 |
| Post Market Change Percent | -1.1467 |
| Post Market Price | 0.25 |
| Post Market Time | 1,787,959,804 |
| Previous Close | 0.257 |
| Price Eps Current Year | -0.17441379 |
| Price Hint | 4 |
| Price To Book | 0.4581522 |
| Price To Sales Trailing12 Months | 4.4873734 |
| Profit Margins | 0.0 |
| Quick Ratio | 2.835 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | hold |
| Recommendation Mean | 3.0 |
| Region | US |
| Regular Market Change | -0.00409999 |
| Regular Market Change Percent | -1.59533 |
| Regular Market Day High | 0.2589 |
| Regular Market Day Low | 0.246 |
| Regular Market Day Range | 0.246 - 0.2589 |
| Regular Market Open | 0.2569 |
| Regular Market Previous Close | 0.257 |
| Regular Market Price | 0.2529 |
| Regular Market Time | 1,787,947,200 |
| Regular Market Volume | 448,950 |
| Return On Assets | -0.8321 |
| Return On Equity | -1.66457 |
| Revenue Growth | 5.049 |
| Revenue Per Share | 0.061 |
| Sand P52 Week Change | 0.20504117 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 44,376,911 |
| Shares Percent Shares Out | 0.044 |
| Shares Short | 1,952,907 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 1,596,248 |
| Short Name | VistaGen Therapeutics, Inc. |
| Short Percent Of Float | 0.044099998 |
| Short Ratio | 0.32 |
| Source Interval | 15 |
| State | CA |
| Symbol | VTGN |
| Target High Price | 1.0 |
| Target Low Price | 1.0 |
| Target Mean Price | 1.0 |
| Target Median Price | 1.0 |
| Total Cash | 31,730,000 |
| Total Cash Per Share | 0.715 |
| Total Debt | 783,000 |
| Total Revenue | 2,501,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.63 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.01945 |
| Two Hundred Day Average Change | -0.76654994 |
| Two Hundred Day Average Change Percent | -0.75192505 |
| Type Disp | Equity |
| Volume | 448,950 |
| Website | https://www.vistagen.com |
| Zip | 94,080 |