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Verastem, Inc. (VSTM)

Healthcare | Biotechnology | Needham, United States | NasdaqCM
7.22 USD -0.16 (-2.168%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 7.16 -0.06 (-0.063%) ⇩ (Aug. 28, 2026, 7:53 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 6:03 a.m. EDT

Verastem presents a classic biotech dilemma: a company with massive analyst optimism and a 'strong buy' consensus is trading at a discount that reflects its precarious financial reality rather than its potential. Fundamentally, the business is burning cash aggressively with negative operating margins and no free cash flow, while the balance sheet shows significant debt relative to equity. Despite a recent surge in revenue growth, the stock has suffered a brutal multi-year decline, dropping nearly half its value over the last nine years, which suggests the market has deeply questioned the sustainability of its pipeline or execution capabilities. The short-term outlook remains murky. While the stock recently rallied off its lows, the technical setup is mixed, trading below its key moving averages, and the statistical forecasting models offer no directional edge, labeling the signal as low confidence noise. This lack of statistical clarity aligns with the heavy put activity seen in the options chain, where traders are hedging against further drops rather than betting on a rally. Crucially, there is no dividend to provide a floor or income stream, making this a pure speculation on a turnaround story. The disconnect between the aggressive analyst price targets and the deteriorating operational metrics creates a high-risk environment. Until the company demonstrates a path to profitability or a clear catalyst that resolves the multi-year decline, the prudent assessment is neutral; the fundamentals are too fragile to warrant a bullish entry, yet the valuation isn't so broken as to guarantee a recovery.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.505797
AutoETS0.536266
AutoTheta0.771880
AutoARIMA0.831610

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 31%
H-stat 3.73
Ljung-Box p 0.000
Jarque-Bera p 0.018
Excess Kurtosis 0.43
Attribute Value
Sector Healthcare
Debt to Equity Ratio 168.707
Revenue per Share 0.985
Market Cap 653,868,032
Forward P/E -9.63
Beta 0.29
Profit Margins -231.59%
Website https://www.verastem.com

As of Aug. 22, 2026, 6:03 a.m. EDT: Speculators are positioning for a range-bound outcome with a distinct skew toward downside protection. Put open interest significantly exceeds call open interest across nearly all expirations, particularly in the near term where out-of-the-money puts dominate the order book. While there is some volume in deep out-of-the-money calls suggesting a speculative hope for a breakout, the overwhelming majority of capital is deployed in strikes below the current price, indicating a market consensus that the stock will likely trade lower or consolidate without a strong upward trend.


Info Dump

Attribute Value
52 Week Change -0.19956619
Address1 117 Kendrick Street
Address2 Suite 500
All Time High 225.84
All Time Low 2.1
Ask 9.24
Ask Size 2
Audit Risk 8
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 1,748,700
Average Daily Volume3 Month 2,483,208
Average Volume 2,483,208
Average Volume10Days 1,748,700
Beta 0.292
Bid 7.24
Bid Size 1
Board Risk 8
Book Value 0.552
City Needham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 7.22
Current Ratio 2.255
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 7.365
Day Low 7.185
Debt To Equity 168.707
Display Name Verastem
Earnings Call Timestamp End 1,786,048,200
Earnings Call Timestamp Start 1,786,048,200
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,793,736,000
Earnings Timestamp Start 1,793,736,000
Ebitda -158,647,008
Ebitda Margins -1.8125701
Enterprise To Ebitda -3.794
Enterprise To Revenue 6.876
Enterprise Value 601,845,056
Eps Current Year -1.8
Eps Forward -0.75
Eps Trailing Twelve Months -2.44
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 5.7268
Fifty Day Average Change 1.4931998
Fifty Day Average Change Percent 0.26073894
Fifty Two Week Change Percent -19.95662
Fifty Two Week High 11.25
Fifty Two Week High Change -4.03
Fifty Two Week High Change Percent -0.35822225
Fifty Two Week Low 3.43
Fifty Two Week Low Change 3.7899997
Fifty Two Week Low Change Percent 1.1049562
Fifty Two Week Range 3.43 - 11.25
Financial Currency USD
First Trade Date Milliseconds 1,327,674,600,000
Float Shares 70,572,467
Forward Eps -0.75
Forward P E -9.626666
Free Cashflow -103,429,624
Full Exchange Name NasdaqCM
Full Time Employees 102
Fullday Change -0.16
Fullday Change Percent -2.16803
Fullday Price 7.1571
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.87644994
Gross Profits 76,712,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00901
Held Percent Institutions 1.1061
Implied Shares Outstanding 90,563,441
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,685,577,600
Last Split Factor 1:12
Long Business Summary Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, which is an orally administered, small molecule dual RAF/MEK inhibitor developed to block MEK kinase activity and the compensatory reactivation of MEK by upstream RAF, thereby targeting the RAS/MAPK signaling pathway that is commonly activated in various cancers; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors. The company is involved in clinical studies, including RAMP 301, a randomized global confirmatory trial to evaluate the combination of Avutometinib and Defactinib for the treatment of patients with recurrent low-grade serous ovarian cancer; RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of Avutometinib and in combination with Defactinib; and FRAME, an investigation of Avutometinib and Defactinib in patients with KRAS mutant cancers and subsequent analyses; and RAMP 205. It has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing Avutometinib; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer's inhibitors of FAK for therapeutic, diagnostic, and prophylactic uses in humans. In addition, it has a clinical collaboration agreement with Amgen, Inc. to evaluate the combination of Avutometinib with Amgen's KRAS-G12C inhibitor LUMAKRAS, which in Phase 1/2 trial entitled RAMP 203; VS-7375, and VS-7375-101 is a discovery and development collaboration with GenFleet Therapeutics to advance new programs targeting RAS pathway-driven cancers; and AVMAPKI, FAKZYNJA, CO-PACK, is an avutometinib capsules, and defactinib tablets. The company was incorporated in 2010 and is headquartered in Needham, Massachusetts.
Long Name Verastem, Inc.
Market us_market
Market Cap 653,868,032
Market State CLOSED
Max Age 86,400
Message Board Id finmb_115881768
Most Recent Quarter 1,782,777,600
Net Income To Common -202,698,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 668,358,194
Number Of Analyst Opinions 8
Open 7.32
Operating Cashflow -162,195,008
Operating Margins -0.81615996
Overall Risk 7
Payout Ratio 0.0
Phone 781 292 4200
Post Market Change -0.06289959
Post Market Change Percent -0.8711855
Post Market Price 7.1571
Post Market Time 1,787,961,233
Previous Close 7.38
Price Eps Current Year -4.0111113
Price Hint 2
Price To Book 13.07971
Price To Sales Trailing12 Months 7.4705577
Profit Margins -2.31586
Quick Ratio 2.119
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.11111
Region US
Regular Market Change -0.16
Regular Market Change Percent -2.16803
Regular Market Day High 7.365
Regular Market Day Low 7.185
Regular Market Day Range 7.185 - 7.365
Regular Market Open 7.32
Regular Market Previous Close 7.38
Regular Market Price 7.22
Regular Market Time 1,787,947,201
Regular Market Volume 1,083,493
Return On Assets -0.49592
Return On Equity -4.7116103
Revenue Growth 17.754
Revenue Per Share 0.985
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 7
Shares Outstanding 90,563,441
Shares Percent Shares Out 0.20879999
Shares Short 18,909,052
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 20,103,345
Short Name Verastem, Inc.
Short Percent Of Float 0.21
Short Ratio 8.94
Source Interval 15
State MA
Symbol VSTM
Target High Price 18.0
Target Low Price 9.0
Target Mean Price 14.75
Target Median Price 15.0
Total Cash 136,352,992
Total Cash Per Share 1.506
Total Debt 84,330,000
Total Revenue 87,526,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.44
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.2674
Two Hundred Day Average Change 0.9526
Two Hundred Day Average Change Percent 0.15199286
Type Disp Equity
Volume 1,083,493
Website https://www.verastem.com
Zip 2,494