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Unicycive Therapeutics, Inc. (UNCY)

Healthcare | Biotechnology | Mountain View, United States | NasdaqCM
5.27 USD -0.24 (-4.273%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 5.32 +0.06 (1.045%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 3:50 a.m. EDT

The investment case for Unicycive Therapeutics is currently paralyzed by a stark contradiction between optimistic analyst targets and deteriorating operational reality. While analysts project a mean price of $28, implying a massive upside, the company's fundamentals tell a different story: it is burning cash, reporting negative returns on equity, and recently suffered an FDA rejection that likely triggered the heavy put option positioning seen in the data. The stock has recovered somewhat from a multi-year decline, showing a recent uptick in price, but the lack of consecutive positive annual returns and the persistent cash burn suggest the recovery is fragile. With no dividend to provide income and a balance sheet that requires constant capital infusion, the security remains a speculative hold rather than a conviction buy until the clinical pipeline proves capable of generating sustainable revenue.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.419362
AutoTheta0.429026
MSTL0.429153
AutoETS0.503141

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 33%
H-stat 0.98
Ljung-Box p 0.564
Jarque-Bera p 0.000
Excess Kurtosis 8.11
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.26
Market Cap 144,224,288
Forward P/E 3.73
Beta 1.78
Website https://unicycive.com

As of Aug. 22, 2026, 3:50 a.m. EDT: Speculators are heavily positioned for downside protection, with massive open interest in out-of-the-money puts (strikes $2.50 and $5.00) relative to calls. This 'put skew' suggests a fear of further decline rather than a bullish bet on a rally, despite the stock trading near its 52-week high.


Info Dump

Attribute Value
52 Week Change 0.27314818
Address1 1,975 West El Camino Real
Address2 Suite 204
All Time High 87.3
All Time Low 2.02
Ask 5.31
Ask Size 1
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 701,680
Average Daily Volume3 Month 1,525,674
Average Volume 1,525,674
Average Volume10Days 701,680
Beta 1.782
Bid 5.31
Bid Size 3
Book Value 1.912
City Mountain View
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 5.265
Current Ratio 3.813
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 5.47
Day Low 5.26
Debt To Equity 1.26
Display Name Unicycive Therapeutics
Earnings Timestamp End 1,794,486,600
Earnings Timestamp Start 1,794,486,600
Ebitda -33,094,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.596
Enterprise Value 85,903,928
Eps Current Year -1.20857
Eps Forward 1.41286
Eps Trailing Twelve Months -1.67
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 5.6611
Fifty Day Average Change -0.39610004
Fifty Day Average Change Percent -0.069968745
Fifty Two Week Change Percent 27.314817
Fifty Two Week High 8.74
Fifty Two Week High Change -3.475
Fifty Two Week High Change Percent -0.39759725
Fifty Two Week Low 3.71
Fifty Two Week Low Change 1.5549998
Fifty Two Week Low Change Percent 0.41913742
Fifty Two Week Range 3.71 - 8.74
Financial Currency USD
First Trade Date Milliseconds 1,626,096,600,000
Float Shares 27,225,728
Forward Eps 1.41286
Forward P E 3.7264836
Free Cashflow -12,716,250
Full Exchange Name NasdaqCM
Full Time Employees 21
Fullday Change -0.235
Fullday Change Percent -4.27273
Fullday Price 5.32
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.0226
Held Percent Institutions 0.42244
Implied Shares Outstanding 27,393,027
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-13
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,750,377,600
Last Split Factor 1:10
Long Business Summary Unicycive Therapeutics, Inc., a clinical-stage biotechnology company, identifies, develops, and commercializes therapies for the treatment of kidney diseases in the United States. It develops oxylanthanum carbonate, a lanthanum-based phosphate binding agent, which is for the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis; and UNI-494, a nicotinamide ester derivative and a selective ATP-sensitive mitochondrial potassium channel activator, which is in Phase I clinical trial for the treatment of acute kidney injury and pre-clinical stage for the treatment of chronic kidney disease. The company was incorporated in 2016 and is headquartered in Mountain View, California.
Long Name Unicycive Therapeutics, Inc.
Market us_market
Market Cap 144,224,288
Market State CLOSED
Max Age 86,400
Message Board Id finmb_605176729
Most Recent Quarter 1,782,777,600
Net Income To Common -35,223,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 153,482,466
Number Of Analyst Opinions 9
Open 5.46
Operating Cashflow -27,839,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 650 351 4495
Post Market Change 0.055000305
Post Market Change Percent 1.0446402
Post Market Price 5.32
Post Market Time 1,787,959,806
Previous Close 5.5
Price Eps Current Year -4.356388
Price Hint 2
Price To Book 2.7536612
Profit Margins 0.0
Quick Ratio 3.284
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.22222
Region US
Regular Market Change -0.235
Regular Market Change Percent -4.27273
Regular Market Day High 5.47
Regular Market Day Low 5.26
Regular Market Day Range 5.26 - 5.47
Regular Market Open 5.46
Regular Market Previous Close 5.5
Regular Market Price 5.265
Regular Market Time 1,787,947,200
Regular Market Volume 608,227
Return On Assets -0.40588
Return On Equity -1.01072
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 27,393,027
Shares Percent Shares Out 0.1491
Shares Short 4,153,197
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 4,939,936
Short Name Unicycive Therapeutics, Inc.
Short Percent Of Float 0.1525
Short Ratio 5.09
Source Interval 15
State CA
Symbol UNCY
Target High Price 50.0
Target Low Price 15.0
Target Mean Price 28.22222
Target Median Price 25.0
Total Cash 61,425,000
Total Cash Per Share 2.205
Total Debt 671,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.67
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.421775
Two Hundred Day Average Change -1.156775
Two Hundred Day Average Change Percent -0.18013322
Type Disp Equity
Volume 608,227
Website https://unicycive.com
Zip 94,040