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Unicycive Therapeutics, Inc. (UNCY)

Healthcare | Biotechnology | Mountain View, United States | NasdaqCM
5.09 USD -0.12 (-2.303%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 5.06 -0.03 (-0.030%) ⇩ (July 13, 2026, 7:45 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:37 a.m. EDT

The investment case for Unicycive Therapeutics is currently broken by a catastrophic multi-year decline and a specific regulatory failure. Despite a recent technical bounce and a modest year-over-year gain, the stock has lost nearly 90% of its value over the last four years, with the most recent annual period showing a severe -60% drop. This is not a temporary correction; it is a structural implosion driven by the FDA's issuance of a Complete Response Letter regarding manufacturing issues for their kidney disease drug. The market has correctly priced this as a potential value trap where the business model is under existential threat. While analysts project a massive upside based on theoretical potential, the reality of the rejected application and the company's burning cash pile makes holding this position dangerous. The options market confirms this pessimism, with traders buying deep out-of-the-money puts to hedge against further ruin rather than betting on a comeback. Until the FDA issues a new approval or a credible path to resolution is demonstrated, the long-term outlook remains bleak.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.082458
AutoTheta0.084170
AutoETS0.085185
AutoARIMA0.085186

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 25%
H-stat 2.19
Ljung-Box p 0.001
Jarque-Bera p 0.000
Excess Kurtosis 5.61
Attribute Value
Sector Healthcare
Debt to Equity Ratio 2.162
Market Cap 139,430,512
Forward P/E 0.99
Beta 1.79
Website https://unicycive.com

As of July 11, 2026, 4:37 a.m. EDT: Speculators are heavily positioned for downside protection, with massive open interest in out-of-the-money puts (strikes at 2.5) compared to negligible call volume. This indicates a strong consensus fear of further price collapse rather than a bullish bet on recovery.


Info Dump

Attribute Value
52 Week Change 0.0676229
Address1 1,975 West El Camino Real
Address2 Suite 204
All Time High 87.3
All Time Low 2.02
Ask 6.37
Ask Size 2
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 4,720,400
Average Daily Volume3 Month 1,437,209
Average Volume 1,437,209
Average Volume10Days 4,720,400
Beta 1.787
Bid 3.68
Bid Size 2
Book Value 1.494
City Mountain View
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 5.09
Current Ratio 2.399
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 5.19
Day Low 4.94
Debt To Equity 2.162
Display Name Unicycive Therapeutics
Earnings Timestamp End 1,747,221,300
Earnings Timestamp Start 1,747,221,300
Ebitda -29,931,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.744
Enterprise Value 82,132,136
Eps Current Year -1.415
Eps Forward 5.14625
Eps Trailing Twelve Months -2.19
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 7.2426
Fifty Day Average Change -2.1525998
Fifty Day Average Change Percent -0.29721367
Fifty Two Week Change Percent 6.76229
Fifty Two Week High 8.74
Fifty Two Week High Change -3.6499996
Fifty Two Week High Change Percent -0.4176201
Fifty Two Week Low 3.71
Fifty Two Week Low Change 1.3800001
Fifty Two Week Low Change Percent 0.37196767
Fifty Two Week Range 3.71 - 8.74
Financial Currency USD
First Trade Date Milliseconds 1,626,096,600,000
Float Shares 24,280,471
Forward Eps 5.14625
Forward P E 0.98906976
Free Cashflow -6,922,125
Full Exchange Name NasdaqCM
Full Time Employees 21
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.02358
Held Percent Institutions 0.32652
Implied Shares Outstanding 27,393,027
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-13
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,750,377,600
Last Split Factor 1:10
Long Business Summary Unicycive Therapeutics, Inc., a clinical-stage biotechnology company, identifies, develops, and commercializes therapies for the treatment of kidney diseases in the United States. It develops oxylanthanum carbonate, a lanthanum-based phosphate binding agent, which is for the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis; and UNI-494, a nicotinamide ester derivative and a selective ATP-sensitive mitochondrial potassium channel activator, which is in Phase I clinical trial for the treatment of acute kidney injury and pre-clinical stage for the treatment of chronic kidney disease. The company was incorporated in 2016 and is headquartered in Mountain View, California.
Long Name Unicycive Therapeutics, Inc.
Market us_market
Market Cap 139,430,512
Market State PREPRE
Max Age 86,400
Message Board Id finmb_605176729
Most Recent Quarter 1,774,915,200
Net Income To Common -39,888,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 143,128,566
Number Of Analyst Opinions 10
Open 5.19
Operating Cashflow -28,655,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 650 351 4495
Post Market Change -0.030100346
Post Market Change Percent -0.59136236
Post Market Price 5.0599
Post Market Time 1,783,986,301
Previous Close 5.21
Price Eps Current Year -3.5971735
Price Hint 2
Price To Book 3.4069614
Profit Margins 0.0
Quick Ratio 2.061
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.2
Region US
Regular Market Change -0.12
Regular Market Change Percent -2.30326
Regular Market Day High 5.19
Regular Market Day Low 4.94
Regular Market Day Range 4.94 - 5.19
Regular Market Open 5.19
Regular Market Previous Close 5.21
Regular Market Price 5.09
Regular Market Time 1,783,972,801
Regular Market Volume 1,125,901
Return On Assets -0.40557998
Return On Equity -1.63136
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 27,393,027
Shares Percent Shares Out 0.1705
Shares Short 4,671,324
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 2,837,490
Short Name Unicycive Therapeutics, Inc.
Short Percent Of Float 0.1745
Short Ratio 1.94
Source Interval 15
State CA
Symbol UNCY
Target High Price 90.0
Target Low Price 13.0
Target Mean Price 38.59
Target Median Price 33.5
Total Cash 54,586,000
Total Cash Per Share 2.044
Total Debt 815,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.19
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 6.302825
Two Hundred Day Average Change -1.2128248
Two Hundred Day Average Change Percent -0.1924256
Type Disp Equity
Volume 1,125,901
Website https://unicycive.com
Zip 94,040