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Entrada Therapeutics, Inc. (TRDA)

Healthcare | Biotechnology | Boston, United States | NasdaqGM
4.37 USD -0.41 (-8.577%) ⇩ (Oct. 16, 2026, 4 p.m. EDT)
After hours: 4.41 +0.04 (0.915%) ⇧ (Oct. 16, 2026, 4 p.m. EDT)

Short-term:★☆☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 11:07 a.m. EDT

Entrada Therapeutics presents a classic value trap where a distressed balance sheet and collapsing revenue mask a speculative biotech narrative. Fundamentally, the company is in severe trouble: revenue has plummeted by nearly 54% year-over-year, operating margins are deeply negative at -50%, and free cash flow is burning through reserves at a rapid pace. The stock has already punished investors severely, dropping nearly 60% over the last three years, yet the business fundamentals remain broken with no path to profitability visible. While the low price-to-book ratio offers a mathematical discount, it reflects the reality of a failing operation rather than a bargain opportunity. The short-term outlook remains bleak. Technical indicators show the stock trading well below its 50-day and 200-day averages, confirming a downtrend. Furthermore, the options market is screaming caution; traders are buying protection at strikes far above the current level, indicating a fear of continued decline rather than anticipation of a recovery. The statistical forecasting model, which captures short-term noise, also leans slightly negative, reinforcing the lack of immediate bullish momentum. Despite the dire fundamentals, a glimmer of hope exists in the analyst community, with a mean price target suggesting significant upside potential. However, this optimism appears disconnected from the current operational reality and is likely priced in based on a single future clinical trial success. Until there is concrete evidence of revenue stabilization or a definitive positive trial readout that changes the growth trajectory, the investment case remains fundamentally unsound.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.120191
MSTL0.146775
AutoETS0.150906
AutoTheta0.157017

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 30%
H-stat 16.72
Ljung-Box p 0.000
Jarque-Bera p 0.096
Excess Kurtosis -0.39
Attribute Value
Sector Healthcare
Debt to Equity Ratio 20.798
Revenue per Share 0.112
Market Cap 170,153,232
Forward P/E -1.45
Beta -0.24
Website https://www.entradatx.com

As of Oct. 10, 2026, 11:07 a.m. EDT: Speculators are positioning defensively with heavy put volume at strikes significantly above the current price (7.5 and 10.0), while call interest is sparse and concentrated deep in-the-money. This distribution suggests a consensus expectation of further downside rather than a catalyst-driven rally.


Info Dump

Attribute Value
52 Week Change -0.30080003
Address1 One Design Center Place
Address2 Suite 17- 500
All Time High 36.85
All Time Low 4.109
Ask 8.87
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 372,850
Average Daily Volume3 Month 355,104
Average Volume 355,104
Average Volume10Days 372,850
Beta -0.238
Bid 5.21
Bid Size 2
Board Risk 4
Book Value 6.473
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.37
Current Ratio 10.889
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 4.85
Day Low 4.345
Debt To Equity 20.798
Display Name Entrada Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,785,933,000
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -170,863,008
Ebitda Margins 0.0
Enterprise To Ebitda 0.099
Enterprise To Revenue -3.605
Enterprise Value -16,891,980
Eps Current Year -3.79429
Eps Forward -3.01
Eps Trailing Twelve Months -3.96
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.5826
Fifty Day Average Change -2.2126002
Fifty Day Average Change Percent -0.33612862
Fifty Two Week Change Percent -30.080002
Fifty Two Week High 16.45
Fifty Two Week High Change -12.080001
Fifty Two Week High Change Percent -0.7343465
Fifty Two Week Low 4.109
Fifty Two Week Low Change 0.26099968
Fifty Two Week Low Change Percent 0.06351902
Fifty Two Week Range 4.109 - 16.45
Financial Currency USD
First Trade Date Milliseconds 1,635,514,200,000
Float Shares 22,668,665
Forward Eps -3.01
Forward P E -1.4518272
Free Cashflow -77,671,624
Full Exchange Name NasdaqGM
Full Time Employees 152
Fullday Change -0.37000036
Fullday Change Percent -7.7405934
Fullday Price 4.37
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -134,355,008
Has Pre Post Market Data 1
Held Percent Insiders 0.12235
Held Percent Institutions 0.82216
Implied Shares Outstanding 38,936,669
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-10-29
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Entrada Therapeutics, Inc., is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. The Company's Endosomal Escape Vehicle, therapeutic candidates are based on a novel therapeutic; a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases. Its preclinical product includes ENTR-601-44; ENTR-601-45; and VX-670. The company was formerly known as CycloPorters, Inc., and changed its name to Entrada Therapeutics, Inc., in October 2017. Entrada Therapeutics, Inc. was incorporated in 2016 and is headquartered in Boston, Massachusetts.
Long Name Entrada Therapeutics, Inc.
Market us_market
Market Cap 170,153,232
Market State CLOSED
Max Age 86,400
Message Board Id finmb_595472652
Most Recent Quarter 1,782,777,600
Net Income To Common -165,778,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 253,088,348
Number Of Analyst Opinions 4
Open 4.79
Operating Cashflow -134,674,000
Operating Margins -50.07016
Overall Risk 7
Payout Ratio 0.0
Phone 857 520 9158
Post Market Change 0.03999996
Post Market Change Percent 0.91533095
Post Market Price 4.41
Post Market Time 1,792,180,807
Previous Close 4.78
Price Eps Current Year -1.1517305
Price Hint 4
Price To Book 0.675112
Price To Sales Trailing12 Months 36.310974
Profit Margins 0.0
Quick Ratio 10.515
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.41
Regular Market Change Percent -8.57741
Regular Market Day High 4.85
Regular Market Day Low 4.345
Regular Market Day Range 4.345 - 4.85
Regular Market Open 4.79
Regular Market Previous Close 4.78
Regular Market Price 4.37
Regular Market Time 1,792,180,801
Regular Market Volume 371,791
Return On Assets -0.29195
Return On Equity -0.54095
Revenue Growth -0.539
Revenue Per Share 0.112
Sand P52 Week Change 0.13723719
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 38,936,669
Shares Percent Shares Out 0.076799996
Shares Short 2,989,455
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 2,345,803
Short Name Entrada Therapeutics, Inc.
Short Percent Of Float 0.1191
Short Ratio 8.99
Source Interval 15
State MA
Symbol TRDA
Target High Price 25.0
Target Low Price 11.0
Target Mean Price 19.0
Target Median Price 20.0
Total Cash 223,004,992
Total Cash Per Share 6.185
Total Debt 48,544,000
Total Revenue 4,686,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.96
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 9.052925
Two Hundred Day Average Change -4.682925
Two Hundred Day Average Change Percent -0.5172831
Type Disp Equity
Volume 371,791
Website https://www.entradatx.com
Zip 2,210