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Theriva Biologics, Inc. (TOVX)

Healthcare | Biotechnology | Rockville, United States | NYSE American
0.25 USD -0.01 (-2.931%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 0.25 +0.00 (1.999%) ⇧ (Aug. 28, 2026, 7:50 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:44 a.m. EDT

The immediate outlook is severely clouded by a relentless multi-year price collapse. The stock has endured five consecutive years of negative annual returns, culminating in a catastrophic -100% loss over the last nine years. This trajectory is not merely a correction; it reflects a market verdict that the business fundamentals are failing to sustain value, evidenced by negative operating margins, negative free cash flow, and a trailing P/E that implies massive losses relative to price. While the company reports clinical progress in oncology trials and maintains a modest cash balance, the capital markets have priced in a high probability of dilution or failure, driving the price to pennies. There is no momentum to exploit here, as the statistical forecast models also register a weak bearish lean with low confidence. For investors, the risk of permanent capital loss outweighs any speculative hope of a turnaround, making this a clear avoidance candidate.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.148411
AutoETS0.153375
MSTL0.154118
AutoTheta0.235843

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 31%
H-stat 7.02
Ljung-Box p 0.000
Jarque-Bera p 0.274
Excess Kurtosis -0.15
Attribute Value
Sector Healthcare
Debt to Equity Ratio 29.154
Revenue per Share 0.01
Market Cap 11,248,293
Trailing P/E 0.18
Forward P/E -1.23
Beta 1.12
Previous Name Synthetic Biologics, Inc.
Website https://therivabio.com

Info Dump

Attribute Value
52 Week Change -0.3902439
Address1 9,605 Medical Center Drive
Address2 Suite 270
All Time High 262,500.0
All Time Low 0.16
Ask 0.2471
Ask Size 700
Average Daily Volume10 Day 603,180
Average Daily Volume3 Month 6,186,250
Average Volume 6,186,250
Average Volume10Days 603,180
Beta 1.118
Bid 0.2471
Bid Size 300
Book Value 0.266
City Rockville
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.2451
Current Ratio 1.129
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 0.2607
Day Low 0.2431
Debt To Equity 29.154
Display Name Theriva Biologics
Dividend Date 1,534,118,400
Earnings Call Timestamp End 1,711,369,800
Earnings Call Timestamp Start 1,711,369,800
Earnings Timestamp End 1,755,174,600
Earnings Timestamp Start 1,755,174,600
Ebitda -11,963,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.29
Enterprise To Revenue 11.548
Enterprise Value 3,464,293
Eps Current Year -0.2
Eps Forward -0.2
Eps Trailing Twelve Months 1.4
Esg Populated 0
Exchange ASE
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.235
Fifty Day Average Change 0.010100007
Fifty Day Average Change Percent 0.042978752
Fifty Two Week Change Percent -39.024387
Fifty Two Week High 0.86
Fifty Two Week High Change -0.6149
Fifty Two Week High Change Percent -0.715
Fifty Two Week Low 0.16
Fifty Two Week Low Change 0.08510001
Fifty Two Week Low Change Percent 0.5318751
Fifty Two Week Range 0.16 - 0.86
Financial Currency USD
First Trade Date Milliseconds 1,166,452,200,000
Float Shares 45,143,241
Forward Eps -0.2
Forward P E -1.2255
Free Cashflow -6,694,250
Full Exchange Name NYSE American
Full Time Employees 15
Fullday Change -0.00739999
Fullday Change Percent -2.93069
Fullday Price 0.25
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 300,000
Has Pre Post Market Data 1
Held Percent Insiders 0.01633
Held Percent Institutions 0.0435
Implied Shares Outstanding 45,892,668
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://www.syntheticbiologics.com/investors
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,724,630,400
Last Split Factor 1:25
Long Business Summary Theriva Biologics, Inc., a clinical-stage company, develops therapeutics to treat cancer and related diseases in areas of high unmet need in the United States. Its lead product candidate, VCN-01 (zabilugene almadenorepvec), a clinical stage oncolytic human adenovirus that is in Phase 1 clinical trials and Phase 2 VIRAGE trial for patients with pancreatic cancer, head and neck squamous cell carcinoma, ovarian cancer, colorectal cancer, and retinoblastoma. The company also develops VCN-11 for treating solid tumors; SYN-004 (ribaxamase), an oral capsule prophylactic therapy that is in Phase 1b/2a clinical trials for the prevention of acute graft-versus-host-disease (aGVHD) in allogeneic hematopoietic cell transplant (HCT); and SYN-020, a recombinant oral formulation of the enzyme intestinal alkaline phosphatase (IAP) for multiple gastrointestinal and metabolic indications. In addition, it develops clinical stage products, such as SYN-006 to prevent aGVH, clostridioides difficile infection, and microbiome damage in patients treated with carbapenem antibiotics; and SYN-007 for preventing antibiotic associated diarrhea with oral ß-lactam antibiotics. The company has a license agreement with Rasayana Therapeutics, Inc. to research, develop, manufacture, and commercialize any product that includes SYN-020, as well as a clinical trial agreement with Washington University School of Medicine in St. Louis to conduct a Phase 1b/2a clinical trial of SYN-004. Theriva Biologics, Inc. is headquartered in Rockville, Maryland.
Long Name Theriva Biologics, Inc.
Market us_market
Market Cap 11,248,293
Market State CLOSED
Max Age 86,400
Message Board Id finmb_24424557
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-28
Net Income To Common -13,128,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 11,587,898
Number Of Analyst Opinions 2
Open 0.2522
Operating Cashflow -12,742,000
Operating Margins -40.22
Payout Ratio 0.0
Phone 301 417 4364
Post Market Change 0.0048999935
Post Market Change Percent 1.9991813
Post Market Price 0.25
Post Market Time 1,787,961,003
Prev Name Synthetic Biologics, Inc.
Previous Close 0.2525
Price Eps Current Year -1.2255
Price Hint 4
Price To Book 0.92142856
Price To Sales Trailing12 Months 37.49431
Profit Margins 0.0
Quick Ratio 1.085
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.00739999
Regular Market Change Percent -2.93069
Regular Market Day High 0.2607
Regular Market Day Low 0.2431
Regular Market Day Range 0.2431 - 0.2607
Regular Market Open 0.2522
Regular Market Previous Close 0.2525
Regular Market Price 0.2451
Regular Market Time 1,787,947,200
Regular Market Volume 559,452
Return On Assets -0.21337
Return On Equity -1.01868
Revenue Per Share 0.01
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 45,892,668
Shares Percent Shares Out 0.0374
Shares Short 1,716,998
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 2,336,498
Short Name Theriva Biologics, Inc.
Short Percent Of Float 0.0374
Short Ratio 3.21
Source Interval 15
State MD
Symbol TOVX
Target High Price 4.0
Target Low Price 1.0
Target Mean Price 2.5
Target Median Price 2.5
Total Cash 11,337,000
Total Cash Per Share 0.247
Total Debt 3,553,000
Total Revenue 300,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 1.4
Trailing P E 0.17507143
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.24015
Two Hundred Day Average Change 0.004950002
Two Hundred Day Average Change Percent 0.020612124
Type Disp Equity
Volume 559,452
Website https://therivabio.com
Zip 20,850