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Tenaya Therapeutics, Inc. (TNYA)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
0.84 USD -0.03 (-3.895%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:09 a.m. EDT

Tenaya Therapeutics presents a stark dichotomy between a distressed balance sheet and a speculative catalyst-driven rally. Fundamentally, the company is in severe trouble: it has burned through nearly 90% of its value over the last three years, carries a massive debt load relative to its tiny equity base, and generates no revenue while posting significant losses. The negative earnings per share and lack of dividends confirm this is not a value play. However, the short-term outlook is buoyed entirely by external validation. Analysts have recently upgraded their targets to $4.00 following positive interim data for its TN-401 drug candidate, which has already pushed the stock up significantly in the last week. This creates a high-risk, high-reward environment suitable only for traders betting on the next clinical milestone, not investors seeking business quality. The options market reflects this perfectly, with heavy call buying at strikes far above the current price, treating the stock as a potential moonshot rather than a stable asset.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.101783
MSTL0.103010
AutoTheta0.113079
AutoETS0.117934

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 42%
H-stat 0.03
Ljung-Box p 0.000
Jarque-Bera p 0.013
Excess Kurtosis 0.41
Attribute Value
Sector Healthcare
Debt to Equity Ratio 9.527
Revenue per Share 0.001
Market Cap 181,519,568
Forward P/E -2.02
Beta 2.84
Website https://www.tenayatherapeutics.com

As of July 11, 2026, 3:09 a.m. EDT: Speculators are positioning for a binary event rather than a trend. Call volume is heavily skewed toward out-of-the-money strikes ($1.50 and $2.00) expiring in late 2026 and early 2027, suggesting bets on a massive price surge driven by clinical data or regulatory milestones. Conversely, put writing is concentrated at lower strikes ($0.50), indicating a defined floor for downside protection. The implied volatility gap between near-term and far-dated options suggests the market prices in a 'lottery ticket' scenario where the stock either doubles on a catalyst or fades back to zero.


Info Dump

Attribute Value
52 Week Change 0.22362864
Address1 171 Oyster Point Boulevard
Address2 Suite 500
All Time High 32.0
All Time Low 0.36
Ask 1.05
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 3,173,310
Average Daily Volume3 Month 3,752,606
Average Volume 3,752,606
Average Volume10Days 3,173,310
Beta 2.837
Bid 0.5918
Bid Size 2
Book Value 0.489
City South San Francisco
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.8365
Current Ratio 5.754
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 0.86
Day Low 0.8
Debt To Equity 9.527
Display Name Tenaya Therapeutics
Earnings Timestamp End 1,778,702,400
Earnings Timestamp Start 1,778,702,400
Ebitda -78,320,000
Ebitda Margins 0.0
Enterprise To Ebitda -1.414
Enterprise To Revenue 492.22
Enterprise Value 110,749,560
Eps Current Year -0.3825
Eps Forward -0.414
Eps Trailing Twelve Months -0.44
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.78928
Fifty Day Average Change 0.04721999
Fifty Day Average Change Percent 0.05982667
Fifty Two Week Change Percent 22.362864
Fifty Two Week High 2.35
Fifty Two Week High Change -1.5135
Fifty Two Week High Change Percent -0.64404255
Fifty Two Week Low 0.532
Fifty Two Week Low Change 0.30449998
Fifty Two Week Low Change Percent 0.5723684
Fifty Two Week Range 0.532 - 2.35
Financial Currency USD
First Trade Date Milliseconds 1,627,651,800,000
Float Shares 216,072,291
Forward Eps -0.414
Forward P E -2.0205314
Free Cashflow -41,898,248
Full Exchange Name NasdaqGS
Full Time Employees 70
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 225,000
Has Pre Post Market Data 1
Held Percent Insiders 0.00466
Held Percent Institutions 0.48362
Implied Shares Outstanding 216,998,877
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-30
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Tenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. Its lead product candidate includes TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy that is in Phase 1b/2 clinical trial; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy, which is in Phase 1b/2 clinical trial; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction that is in phase 1 clinical trial. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.
Long Name Tenaya Therapeutics, Inc.
Market us_market
Market Cap 181,519,568
Market State PRE
Max Age 86,400
Message Board Id finmb_409125654
Most Recent Quarter 1,774,915,200
Net Income To Common -83,005,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 179,859,518
Number Of Analyst Opinions 6
Open 0.8421
Operating Cashflow -64,386,000
Operating Margins -89.17778
Payout Ratio 0.0
Phone 650 825 6990
Pre Market Change -0.025099993
Pre Market Change Percent -3.000597
Pre Market Price 0.8114
Pre Market Time 1,784,018,885
Previous Close 0.8704
Price Eps Current Year -2.186928
Price Hint 4
Price To Book 1.710634
Price To Sales Trailing12 Months 806.75366
Profit Margins 0.0
Quick Ratio 5.453
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.0339
Regular Market Change Percent -3.89476
Regular Market Day High 0.86
Regular Market Day Low 0.8
Regular Market Day Range 0.8 - 0.86
Regular Market Open 0.8421
Regular Market Previous Close 0.8704
Regular Market Price 0.8365
Regular Market Time 1,783,972,800
Regular Market Volume 2,329,374
Return On Assets -0.38464
Return On Equity -0.73591006
Revenue Per Share 0.001
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 216,998,876
Shares Percent Shares Out 0.120900005
Shares Short 26,232,552
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 29,295,482
Short Name Tenaya Therapeutics, Inc.
Short Percent Of Float 0.15720001
Short Ratio 9.42
Source Interval 15
State CA
Symbol TNYA
Target High Price 8.0
Target Low Price 2.0
Target Mean Price 4.0
Target Median Price 3.5
Total Cash 80,887,000
Total Cash Per Share 0.373
Total Debt 10,117,000
Total Revenue 225,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.44
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.971465
Two Hundred Day Average Change -0.134965
Two Hundred Day Average Change Percent -0.13892935
Type Disp Equity
Volume 2,329,374
Website https://www.tenayatherapeutics.com
Zip 94,080