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Tiziana Life Sciences Ltd (TLSA)

Healthcare | Biotechnology | London, United Kingdom | NasdaqCM
1.33 USD +0.10 (8.130%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 1.31 -0.02 (-0.020%) ⇩ (July 13, 2026, 4:45 p.m. EDT)

Short-term:★⯪☆☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5:45 a.m. EDT

The investment case here is a classic 'binary event' play wrapped in a distressed biotech shell. Fundamentally, the company is burning cash with negative free cash flow and a deteriorating balance sheet, offering no safety margin for a traditional value investor. However, the catalysts are compelling: the company is actively dosing patients in Alzheimer's trials and advancing its foralumab program, which has recently triggered analyst price target boosts. The options market confirms this sentiment, with heavy call buying at strikes significantly above the current price, suggesting traders are betting on a successful trial readout or partnership deal to drive the stock higher. The short-term outlook leans positive due to this speculative positioning and upcoming clinical milestones, despite the weak statistical forecast which likely reflects the stock's recent volatility and lack of earnings support.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.106255
AutoARIMA0.106255
MSTL0.109813
AutoTheta0.111206

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 37%
H-stat 0.39
Ljung-Box p 0.000
Jarque-Bera p 0.217
Excess Kurtosis -1.28
Attribute Value
Sector Healthcare
Debt to Equity Ratio 876.923
Market Cap 169,254,640
Forward P/E -6.66
Beta 0.44
Previous Name Tiziana Life Sciences PLC
Website https://www.tizianalifesciences.com

As of July 11, 2026, 5:45 a.m. EDT: Speculators are overwhelmingly bullish on upside potential, evidenced by significant open interest in out-of-the-money calls at strikes of 2.5 and 5.0, while put activity is virtually non-existent. This creates a highly skewed gamma profile where the market is pricing in a binary event-driven rally rather than a steady grind.


Info Dump

Attribute Value
52 Week Change -0.16891891
Address1 14/15 Conduit Street
All Time High 12.17
All Time Low 0.41
Ask 1.24
Ask Size 1
Average Daily Volume10 Day 183,200
Average Daily Volume3 Month 211,101
Average Volume 211,101
Average Volume10Days 183,200
Beta 0.443
Bid 1.17
Bid Size 1
Book Value 0.077
City London
Compensation As Of Epoch Date 1,735,603,200
Country United Kingdom
Crypto Tradeable 0
Currency USD
Current Price 1.33
Current Ratio 0.763
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 1.38
Day Low 1.22
Debt To Equity 876.923
Display Name Tiziana Life Sciences
Earnings Timestamp End 1,752,004,800
Earnings Timestamp Start 1,750,708,800
Ebitda -21,120,000
Ebitda Margins 0.0
Enterprise To Ebitda -7.42
Enterprise Value 156,720,848
Eps Current Year -0.121
Eps Forward -0.19961944
Eps Trailing Twelve Months -0.17
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.3098
Fifty Day Average Change 0.020200014
Fifty Day Average Change Percent 0.015422212
Fifty Two Week Change Percent -16.891891
Fifty Two Week High 2.6
Fifty Two Week High Change -1.2699999
Fifty Two Week High Change Percent -0.4884615
Fifty Two Week Low 1.04
Fifty Two Week Low Change 0.29000008
Fifty Two Week Low Change Percent 0.27884623
Fifty Two Week Range 1.04 - 2.6
Financial Currency USD
First Trade Date Milliseconds 1,542,724,200,000
Float Shares 63,889,409
Forward Eps -0.19961944
Forward P E -6.662678
Free Cashflow -5,476,750
Full Exchange Name NasdaqCM
Full Time Employees 10
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.47647
Held Percent Institutions 0.02944
Implied Shares Outstanding 127,259,131
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,596,153,600
Last Split Factor 2,499:1000
Long Business Summary Tiziana Life Sciences Ltd, together with its subsidiaries, engages in the research and development of therapies for neurodegenerative and neuroinflammatory diseases in the United Kingdom and internationally. It develops Foralumab TZLS-401, a human anti-CD3 monoclonal antibody, which is Phase II clinical trial for the treatment of non-active secondary progressive multiple sclerosis, Alzheimer's disease, multi system atrophy, and amyotrophic lateral sclerosis; and TZLS-501, a human anti-IL-6R monoclonal antibody for the treatment of autoimmune and inflammatory diseases. The company is headquartered in London, the United Kingdom.
Long Name Tiziana Life Sciences Ltd
Market us_market
Market Cap 169,254,640
Market State PREPRE
Max Age 86,400
Message Board Id finmb_261234197
Most Recent Quarter 1,767,139,200
Name Change Date 2,026-07-13
Net Income To Common -18,431,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 156,528,731
Number Of Analyst Opinions 1
Open 1.22
Operating Cashflow -12,847,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 44 20 7495 2379
Post Market Change -0.0200001
Post Market Change Percent -1.5037669
Post Market Price 1.31
Post Market Time 1,783,975,513
Prev Name Tiziana Life Sciences PLC
Previous Close 1.23
Price Eps Current Year -10.991736
Price Hint 4
Price To Book 17.272728
Profit Margins 0.0
Quick Ratio 0.722
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.1
Regular Market Change Percent 8.13008
Regular Market Day High 1.38
Regular Market Day Low 1.22
Regular Market Day Range 1.22 - 1.38
Regular Market Open 1.22
Regular Market Previous Close 1.23
Regular Market Price 1.33
Regular Market Time 1,783,972,800
Regular Market Volume 384,306
Return On Assets -1.1596199
Return On Equity -9.24323
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 127,259,131
Shares Percent Shares Out 0.0123000005
Shares Short 1,565,672
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 1,460,023
Short Name Tiziana Life Sciences Ltd
Short Percent Of Float 0.0431
Short Ratio 7.63
Source Interval 15
Symbol TLSA
Target High Price 9.093458
Target Low Price 9.093458
Target Mean Price 9.093458
Target Median Price 9.093458
Total Cash 4,010,000
Total Cash Per Share 0.033
Total Debt 456,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.17
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.5137
Two Hundred Day Average Change -0.18369997
Two Hundred Day Average Change Percent -0.12135824
Type Disp Equity
Volume 384,306
Website https://www.tizianalifesciences.com
Zip W1S 2XJ