Talphera, Inc. (TLPH)Healthcare | Drug Manufacturers - Specialty & Generic | San Mateo, United States | NasdaqCM
0.80 USD
-0.01
(-0.791%) ⇩
(April 17, 2026, 4 p.m.
EDT)
After hours: 0.80 0.00 (-0.003%) ⇩ (April 17, 2026, 6:36 p.m. EDT) Short-term: ☆☆☆☆☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆ |
Hot Take | April 19, 2026, 12:54 a.m. EDT
Talphera is crashing due to fundamental solvency issues, not a lack of speculative interest, as implied by the model's -16% prediction and the chaotic trading range (0.72-0.85) which is down significantly from its 52-week high of 1.57. The P/E is negative, cash flow is negative, and P/S is 1434x. Any potential catalysts (clinical updates) are years away. There is no catalyst, no volume, and no traps. The lack of puts doesn't mean a bottom is coming; it means nobody cares enough to hedge against the risk of further dilution or failure. |
| Model | MAE |
|---|---|
| AutoTheta ✓ | 0.068386 |
| AutoARIMA | 0.177790 |
| AutoETS | 0.177893 |
| MSTL | 0.179171 |
Forecast horizon: 45 days | Selected: AutoTheta
| Forecast Reliability | |
|---|---|
| Score | 80% |
| H-stat | 0.51 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.195 |
| Excess Kurtosis | -1.22 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 38.151 |
| Revenue per Share | 0.001 |
| Market Cap | 40,169,992 |
| Forward P/E | -2.87 |
| Beta | 0.56 |
| Previous Name | AcelRx Pharmaceuticals, Inc. |
| Website | https://talphera.com |
As of April 19, 2026, 12:54 a.m. EDT: Options volume is negligible and highly idiosyncratic, with no discernible directional thesis. The 'call' OI at strikes resembling 1.0 is dominated by Individual Placement at 1.5 and 2.5 in the June expiry. Crucially, the short-term nearest expiration (June 18) exhibits a distinct lack of put interest: there is zero out-of-the-money put Open Interest, while the total volume for OTM calls is extremely low. The model predicts a directional drop of roughly 16.38% over the next 45 days, though this must be viewed heavily as a trend-following projection rather than a signal of imminent convexity given the vanishingly small open interest in options.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.6326531 |
| Address1 | 1,850 Gateway Drive |
| Address2 | Suite 175 |
| All Time High | 272.8 |
| All Time Low | 0.38 |
| Ask | 0.8353 |
| Ask Size | 1 |
| Average Daily Volume10 Day | 137,940 |
| Average Daily Volume3 Month | 200,201 |
| Average Volume | 200,201 |
| Average Volume10Days | 137,940 |
| Beta | 0.556 |
| Bid | 0.79 |
| Bid Size | 1 |
| Book Value | 0.345 |
| City | San Mateo |
| Compensation As Of Epoch Date | 1,735,603,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 0.8026 |
| Current Ratio | 5.487 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,774,915,200 |
| Day High | 0.8398 |
| Day Low | 0.79 |
| Debt To Equity | 38.151 |
| Display Name | Talphera |
| Earnings Call Timestamp End | 1,755,203,400 |
| Earnings Call Timestamp Start | 1,755,203,400 |
| Earnings Timestamp | 1,774,269,000 |
| Earnings Timestamp End | 1,778,675,400 |
| Earnings Timestamp Start | 1,778,675,400 |
| Ebitda Margins | 0.0 |
| Enterprise To Revenue | 938.857 |
| Enterprise Value | 26,287,988 |
| Eps Current Year | -0.35 |
| Eps Forward | -0.28 |
| Eps Trailing Twelve Months | -0.34 |
| Esg Populated | 0 |
| Exchange | NCM |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 0.8216 |
| Fifty Day Average Change | -0.018999994 |
| Fifty Day Average Change Percent | -0.0231256 |
| Fifty Two Week Change Percent | 63.265312 |
| Fifty Two Week High | 1.57 |
| Fifty Two Week High Change | -0.7674 |
| Fifty Two Week High Change Percent | -0.4887898 |
| Fifty Two Week Low | 0.38 |
| Fifty Two Week Low Change | 0.42260003 |
| Fifty Two Week Low Change Percent | 1.1121054 |
| Fifty Two Week Range | 0.38 - 1.57 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,297,434,600,000 |
| Float Shares | 24,911,799 |
| Forward Eps | -0.28 |
| Forward P E | -2.8664286 |
| Free Cashflow | -6,531,500 |
| Full Exchange Name | NasdaqCM |
| Full Time Employees | 12 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 0.0 |
| Gross Profits | -218,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.25433 |
| Held Percent Institutions | 0.40741003 |
| Implied Shares Outstanding | 50,049,824 |
| Industry | Drug Manufacturers - Specialty & Generic |
| Industry Disp | Drug Manufacturers - Specialty & Generic |
| Industry Key | drug-manufacturers-specialty-generic |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Last Split Date | 1,666,742,400 |
| Last Split Factor | 1:20 |
| Long Business Summary | Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, a nafamostat formulation for direct IV infusion as an investigational product for various indications, such as antiviral, acute respiratory distress syndrome, disseminated intravascular coagulation, and acute pancreatitis, as well as Fedsyra and phenylephrine ready-to-use pre-filled syringe product candidates. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is based in San Mateo, California. |
| Long Name | Talphera, Inc. |
| Market | us_market |
| Market Cap | 40,169,992 |
| Market State | PREPRE |
| Max Age | 86,400 |
| Message Board Id | finmb_33172220 |
| Most Recent Quarter | 1,767,139,200 |
| Name Change Date | 2,026-04-19 |
| Net Income To Common | -14,363,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 40,169,988 |
| Number Of Analyst Opinions | 2 |
| Open | 0.7923 |
| Operating Cashflow | -11,364,000 |
| Operating Margins | -481.57144 |
| Payout Ratio | 0.0 |
| Phone | 650 216 3500 |
| Post Market Change | -0.0026000142 |
| Post Market Change Percent | -0.32394892 |
| Post Market Price | 0.8 |
| Post Market Time | 1,776,465,389 |
| Prev Name | AcelRx Pharmaceuticals, Inc. |
| Previous Close | 0.809 |
| Price Eps Current Year | -2.293143 |
| Price Hint | 4 |
| Price To Book | 2.326377 |
| Price To Sales Trailing12 Months | 1,434.6426 |
| Profit Margins | 0.0 |
| Quick Ratio | 5.351 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.006399989 |
| Regular Market Change Percent | -0.7910987 |
| Regular Market Day High | 0.8398 |
| Regular Market Day Low | 0.79 |
| Regular Market Day Range | 0.79 - 0.8398 |
| Regular Market Open | 0.7923 |
| Regular Market Previous Close | 0.809 |
| Regular Market Price | 0.8026 |
| Regular Market Time | 1,776,456,000 |
| Regular Market Volume | 105,215 |
| Return On Assets | -0.35147998 |
| Return On Equity | -1.14739 |
| Revenue Per Share | 0.001 |
| Sand P52 Week Change | 0.38150132 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 50,049,824 |
| Shares Percent Shares Out | 0.0254 |
| Shares Short | 1,270,880 |
| Shares Short Previous Month Date | 1,772,150,400 |
| Shares Short Prior Month | 1,155,618 |
| Short Name | Talphera, Inc. |
| Short Percent Of Float | 0.0256 |
| Short Ratio | 6.2 |
| Source Interval | 15 |
| State | CA |
| Symbol | TLPH |
| Target High Price | 3.5 |
| Target Low Price | 3.0 |
| Target Mean Price | 3.25 |
| Target Median Price | 3.25 |
| Total Cash | 20,381,000 |
| Total Cash Per Share | 0.407 |
| Total Debt | 6,499,000 |
| Total Revenue | 28,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -0.34 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 0.89245 |
| Two Hundred Day Average Change | -0.08984995 |
| Two Hundred Day Average Change Percent | -0.100677855 |
| Type Disp | Equity |
| Volume | 105,215 |
| Website | https://talphera.com |
| Zip | 94,404 |