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Tectonic Therapeutic, Inc. (TECX)

Healthcare | Biotechnology | Watertown, United States | NasdaqGM
35.62 USD -1.08 (-2.943%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 35.62

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:56 a.m. EDT

The investment case for Tectonic Therapeutic is a classic tale of speculative optimism clashing with deteriorating fundamentals. While the options market is screaming 'moonshot' with massive open interest in far-out-of-the-money calls, the underlying business shows no signs of financial stability. The company is burning cash aggressively, with operating and free cash flows deeply negative, and has posted losses for five of the last seven years. Despite a recent price recovery that ended the multi-year decline, the stock remains down nearly 95% from its peak, and the balance sheet is fragile with significant debt relative to equity. The 'strong buy' analyst consensus appears to be pricing in a binary event—likely a successful Phase 2 trial—but ignores the reality that the company currently lacks the cash reserves to survive a prolonged period of failure without dilution. For now, the stock is a high-risk leveraged bet on a clinical milestone, not a sound investment in a viable business.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.089195
AutoARIMA0.091368
AutoETS0.096034
AutoTheta0.097986

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 33%
H-stat 2.25
Ljung-Box p 0.000
Jarque-Bera p 0.179
Excess Kurtosis -0.38
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.965
Market Cap 696,348,416
Forward P/E -7.61
Beta 0.22
Website https://tectonictx.com

As of Aug. 22, 2026, 2:56 a.m. EDT: Speculators are overwhelmingly bullish, with open interest heavily concentrated in out-of-the-money calls (OTM OI % near 100% across expirations). The largest call positions sit at strikes significantly above the current price ($45 and $55), while put activity is negligible and confined to deep out-of-the-money strikes. This structure indicates a speculative bet on a sharp upward move rather than hedging against downside risk.


Info Dump

Attribute Value
52 Week Change 1.2042043
Address1 490 Arsenal Way
Address2 Suite 210
All Time High 644.4
All Time Low 1.4
Ask 37.17
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 205,690
Average Daily Volume3 Month 186,340
Average Volume 186,340
Average Volume10Days 205,690
Beta 0.216
Bid 29.58
Bid Size 1
Board Risk 7
Book Value 12.236
City Watertown
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 35.62
Current Ratio 22.287
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 36.76
Day Low 34.95
Debt To Equity 1.965
Display Name Tectonic Therapeutic
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -93,661,000
Ebitda Margins 0.0
Enterprise To Ebitda -5.057
Enterprise Value 473,679,424
Eps Forward -4.68
Eps Trailing Twelve Months -4.43
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 32.8934
Fifty Day Average Change 2.7266006
Fifty Day Average Change Percent 0.08289203
Fifty Two Week Change Percent 120.42043
Fifty Two Week High 39.53
Fifty Two Week High Change -3.9099998
Fifty Two Week High Change Percent -0.09891222
Fifty Two Week Low 14.39
Fifty Two Week Low Change 21.23
Fifty Two Week Low Change Percent 1.47533
Fifty Two Week Range 14.39 - 39.53
Financial Currency USD
First Trade Date Milliseconds 1,529,587,800,000
Float Shares 11,911,820
Forward Eps -4.68
Forward P E -7.611111
Free Cashflow -46,723,124
Full Exchange Name NasdaqGM
Full Time Employees 60
Fullday Change -1.08
Fullday Change Percent -2.94278
Fullday Price 35.62
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.37846002
Held Percent Institutions 0.71686
Implied Shares Outstanding 19,549,366
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,718,928,000
Last Split Factor 1:12
Long Business Summary Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines. The company's lead product is TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone, and relaxin. It is also developing TX2100 for the treatment of hereditary hemorrhagic telangiectasia; GPCR modulator bispecific for treating fibrosis; and other GPCR modulators. The company is headquartered in Watertown, Massachusetts.
Long Name Tectonic Therapeutic, Inc.
Market us_market
Market Cap 696,348,416
Market State CLOSED
Max Age 86,400
Message Board Id finmb_711440557
Most Recent Quarter 1,782,777,600
Net Income To Common -85,787,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 717,657,225
Number Of Analyst Opinions 9
Open 36.11
Operating Cashflow -72,140,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 339 666 3320
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 35.62
Post Market Time 1,787,959,806
Previous Close 36.7
Price Hint 2
Price To Book 2.911082
Profit Margins 0.0
Quick Ratio 21.899
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.1
Region US
Regular Market Change -1.08
Regular Market Change Percent -2.94278
Regular Market Day High 36.76
Regular Market Day Low 34.95
Regular Market Day Range 34.95 - 36.76
Regular Market Open 36.11
Regular Market Previous Close 36.7
Regular Market Price 35.62
Regular Market Time 1,787,947,200
Regular Market Volume 157,790
Return On Assets -0.22288999
Return On Equity -0.338
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 19,549,366
Shares Percent Shares Out 0.0883
Shares Short 1,726,909
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 1,936,691
Short Name Tectonic Therapeutic, Inc.
Short Percent Of Float 0.17860001
Short Ratio 9.08
Source Interval 15
State MA
Symbol TECX
Target High Price 93.0
Target Low Price 60.0
Target Mean Price 77.55556
Target Median Price 80.0
Total Cash 227,068,000
Total Cash Per Share 11.615
Total Debt 4,399,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.43
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 26.9748
Two Hundred Day Average Change 8.645199
Two Hundred Day Average Change Percent 0.32049167
Type Disp Equity
Volume 157,790
Website https://tectonictx.com
Zip 2,472