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Sutro Biopharma, Inc. (STRO)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGM
31.55 USD +2.20 (7.496%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 31.55

Short-term: ★★★★☆ | Long-term: ☆☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:17 p.m. EDT

Dramatic technical divergence between analyst sentiment and market reality: While analysts issued upgrades and a "buy" consensus is in place, the options market is screaming 'cautious' to 'fearful,' with heavy put buying suggesting current rallies are viewed as potential 'traps' before a deeper correction in this biotech underperformer.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.074255
MSTL0.266907
AutoARIMA0.275281
AutoETS0.276302

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 80%
H-stat 0.09
Ljung-Box p 0.000
Jarque-Bera p 0.946
Excess Kurtosis -0.21
Attribute Value
Sector Healthcare
Revenue per Share 12.06
Market Cap 522,696,352
Forward P/E -12.72
Beta 1.31
Profit Margins -186.45%
Website https://www.sutrobio.com

As of April 18, 2026, 10:17 p.m. EDT: Options flow is heavily skewed bearish for the immediate future. The May 15 expiration shows massive out-of-the-money put volume (85 contracts) compared to zero ITM put volume and virtually no OTM call interest, indicating a strong hedge against further drops. Conversely, call data is thin with significant OTM support at very low strikes (e.g., 22.5 strike has highest OI), while nearby dates lack conviction at current price levels. This asymmetry suggests speculators are positioning for downside risk or protecting existing long downside positions rather than betting on a near-term breakout above $32.


Info Dump

Attribute Value
52 Week Change 4.7363634
Address1 111 Oyster Point Boulevard
All Time High 283.0
All Time Low 5.2
Ask 32.01
Ask Size 1
Average Analyst Rating 1.6 - Buy
Average Daily Volume10 Day 288,290
Average Daily Volume3 Month 180,485
Average Volume 180,485
Average Volume10Days 288,290
Beta 1.314
Bid 31.18
Bid Size 1
Book Value -15.43
City South San Francisco
Compensation As Of Epoch Date 1,735,603,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 31.55
Current Ratio 2.009
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 32.58
Day Low 29.785
Display Name Sutro Biopharma
Earnings Call Timestamp End 1,741,899,600
Earnings Call Timestamp Start 1,741,899,600
Earnings Timestamp End 1,755,298,800
Earnings Timestamp Start 1,754,953,200
Ebitda -97,628,000
Ebitda Margins -0.95262
Enterprise To Ebitda -4.066
Enterprise To Revenue 3.873
Enterprise Value 396,942,368
Eps Current Year -6.71
Eps Forward -2.48
Eps Trailing Twelve Months -22.49
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 553 9659
Fifty Day Average 22.2158
Fifty Day Average Change 9.3342
Fifty Day Average Change Percent 0.42016044
Fifty Two Week Change Percent 473.63635
Fifty Two Week High 32.58
Fifty Two Week High Change -1.0300026
Fifty Two Week High Change Percent -0.031614564
Fifty Two Week Low 5.3
Fifty Two Week Low Change 26.25
Fifty Two Week Low Change Percent 4.95283
Fifty Two Week Range 5.3 - 32.58
Financial Currency USD
First Trade Date Milliseconds 1,538,055,000,000
Float Shares 15,151,568
Forward Eps -2.48
Forward P E -12.721774
Free Cashflow -112,393,376
Full Exchange Name NasdaqGM
Full Time Employees 137
Gmt Off Set Milliseconds -14,400,000
Gross Margins -0.62383
Gross Profits -63,933,000
Has Pre Post Market Data 1
Held Percent Insiders 0.02459
Held Percent Institutions 0.39973998
Implied Shares Outstanding 16,567,238
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,764,720,000
Last Split Factor 1:10
Long Business Summary Sutro Biopharma, Inc. operates as an oncology company. The company develops site-specific and novel-format antibody drug conjugates (ADCs) that enables its proprietary integrated cell-free protein synthesis platform, XpressCF; and site-specific conjugation platform, XpressCF+. Its lead product candidate includes STRO-004, a tissue factor (TF) targeting ADC for the treatment of TF-expressing solid tumors, including non-small cell lung cancer, head and neck squamous cell carcinoma, cervical cancer, colorectal cancer, pancreatic ductal adenocarcinoma, endometrial cancer, and bladder cancer. The company also develops VAX-24 and Vax-31 pneumococcal conjugate vaccine candidates that is in Phase II/III clinical trials for the treatment of invasive pneumococcal disease in adults and adults and infants; and STRO-003, an ADC directed against an anti-receptor tyrosine kinase-like orphan receptor 1 (ROR1) for the treatment of solid tumors, such as triple negative breast cancer, non-small cell lung cancer, and ovarian cancer, as well as hematological cancers. Sutro Biopharma, Inc. has collaboration and license agreements with Vaxcyte to discover and develop vaccine candidates for the treatment or prophylaxis of infectious diseases; Tasly Biopharmaceuticals Co., Ltd. to develop and commercialize STRO-002 in Greater China; Ipsen to develop and commercialize STRO-003, an ADC targeting ROR1; and Astellas Pharma Inc. to develop immunostimulatory ADC. The company was formerly known as Fundamental Applied Biology, Inc. Sutro Biopharma, Inc. was incorporated in 2003 and is headquartered in South San Francisco, California.
Long Name Sutro Biopharma, Inc.
Market us_market
Market Cap 522,696,352
Market State CLOSED
Max Age 86,400
Message Board Id finmb_38768157
Most Recent Quarter 1,767,139,200
Net Income To Common -191,086,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 523,193,376
Number Of Analyst Opinions 9
Open 30.18
Operating Cashflow -177,231,008
Operating Margins -2.88976
Payout Ratio 0.0
Phone 650 881 6500
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 31.55
Post Market Time 1,776,456,605
Previous Close 29.35
Price Eps Current Year -4.701937
Price Hint 2
Price To Book -2.044718
Price To Sales Trailing12 Months 5.1002727
Profit Margins -1.86454
Quick Ratio 1.935
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.6
Region US
Regular Market Change 2.2
Regular Market Change Percent 7.49574
Regular Market Day High 32.58
Regular Market Day Low 29.785
Regular Market Day Range 29.785 - 32.58
Regular Market Open 30.18
Regular Market Previous Close 29.35
Regular Market Price 31.55
Regular Market Time 1,776,456,000
Regular Market Volume 296,982
Return On Assets -0.23382999
Revenue Growth -0.214
Revenue Per Share 12.06
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 16,567,238
Shares Percent Shares Out 0.038599998
Shares Short 639,714
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 517,388
Short Name Sutro Biopharma, Inc.
Short Percent Of Float 0.0387
Short Ratio 3.14
Source Interval 15
State CA
Symbol STRO
Target High Price 55.0
Target Low Price 9.0
Target Mean Price 31.44444
Target Median Price 29.0
Total Cash 141,428,000
Total Cash Per Share 8.537
Total Debt 15,674,000
Total Revenue 102,484,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -22.49
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 12.85605
Two Hundred Day Average Change 18.69395
Two Hundred Day Average Change Percent 1.4540976
Type Disp Equity
Volume 296,982
Website https://www.sutrobio.com
Zip 94,080