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Scholar Rock Holding Corporation (SRRK)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGS
47.80 USD -2.16 (-4.323%) ⇩ (April 20, 2026, 4 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 12:05 a.m. EDT

Scholar Rock is exhibiting a classic 'squeeze' to the upside ahead of Q1 results. While analysts citing negative P/E valuations keep the fundamental narrative weak for value investors, the options flow tells a different story: smart money is buying deep OTM calls for the next 1-3 months (targeting 70) and establishing call positions at 55, suggesting an expectation of a breakthrough beyond current lows. The heavy put buying at the 35-45 range is likely risk management for big buyers, not a bearish signal. Investors with a 1-2 month horizon should lean long, but multi-year holders must ignore the current unprofitability.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.049857
AutoETS0.064611
AutoARIMA0.064708
MSTL0.066907

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 54%
H-stat 1.84
Ljung-Box p 0.000
Jarque-Bera p 0.030
Excess Kurtosis -0.09
Attribute Value
Sector Healthcare
Debt to Equity Ratio 44.367
Market Cap 5,491,411,968
Forward P/E -22.28
Beta 0.69
Website https://www.scholarrock.com

As of April 19, 2026, 12:05 a.m. EDT: Short-term sentiment is aggressively bullish near-term. Apr 17 calls show top OI at the 55 strike, suggesting a target slightly above current prices (~50). Conversely, Apr 17 puts have massive open interest at deep strikes (35, 45), likely representing short-term hedges or aggressive downside protection. However, looking further out to July 17, there is notable unusual volume (Vol > OI) at the 40 strike calls, indicating speculators are positioning for a move back toward earnings recovery levels. Long-dated calls (Oct/Jan) skew heavy on OTM calls (70, 65 strikes), signaling a long-term upside bias despite current negative analyst consensus on valuation.


Info Dump

Attribute Value
52 Week Change 0.5107459
Address1 301 Binney Street
Address2 3rd Floor
All Time High 70.0
All Time Low 4.325
Ask 47.91
Ask Size 1
Audit Risk 4
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 1,516,970
Average Daily Volume3 Month 1,397,757
Average Volume 1,397,757
Average Volume10Days 1,516,970
Beta 0.687
Bid 47.64
Bid Size 2
Board Risk 9
Book Value 2.263
City Cambridge
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 47.8
Current Ratio 6.95
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 49.69
Day Low 47.7
Debt To Equity 44.367
Display Name Scholar Rock Holding
Earnings Call Timestamp End 1,778,155,200
Earnings Call Timestamp Start 1,778,155,200
Earnings Timestamp 1,778,157,000
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -382,987,008
Ebitda Margins 0.0
Enterprise To Ebitda -13.663
Enterprise Value 5,232,763,904
Eps Current Year -3.01786
Eps Forward -2.14544
Eps Trailing Twelve Months -3.29
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 46.1494
Fifty Day Average Change 1.6506004
Fifty Day Average Change Percent 0.035766456
Fifty Two Week Change Percent 51.07459
Fifty Two Week High 51.625
Fifty Two Week High Change -3.8250008
Fifty Two Week High Change Percent -0.07409202
Fifty Two Week Low 27.07
Fifty Two Week Low Change 20.73
Fifty Two Week Low Change Percent 0.76579237
Fifty Two Week Range 27.07 - 51.625
Financial Currency USD
First Trade Date Milliseconds 1,527,255,000,000
Float Shares 95,611,457
Forward Eps -2.14544
Forward P E -22.27981
Free Cashflow -162,622,256
Full Exchange Name NasdaqGS
Full Time Employees 289
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Gross Profits -208,440,000
Has Pre Post Market Data 1
Held Percent Insiders 0.035669997
Held Percent Institutions 1.10806
Implied Shares Outstanding 114,883,096
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Scholar Rock Holding Corporation, a biopharmaceutical company, focuses on improving the lives of children and adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. The company's novel understanding of the molecular mechanisms of growth factor activation within the transforming growth factor beta (TGFß) superfamily has enabled the development of a proprietary platform. This platform is used for the development of monoclonal antibodies that locally and selectively target the precursor, or latent, forms of growth factors. The company is developing Apitegromab, an inhibitor of the activation of myostatin, which is in a Phase 2 clinical trial for the treatment of SMA and facioscapulohumeral muscular dystrophy (FSHD). Additionally, SRK-439, an anti-pro/latent myostatin antibody, is in a Phase 1 clinical trial for the treatment of patients with rare, severe, and debilitating neuromuscular diseases. SRK-181 is a Phase 2-ready investigational inhibitor of latent TGFß1 for the treatment of patients with solid tumors that are resistant to anti-PD-(L)1 antibody therapies. The company also offers products in pre-clinical development, including SRK-373, a selective inhibitor of the latent TGFß1 isoform with selective activity in the fibrotic extracellular matrix, for the treatment of fibrotic diseases, and SRK-256, an inhibitor of RGMc, or hemojuvelin, for the treatment of iron-restricted anemias. Scholar Rock Holding Corporation is also developing a pipeline that includes programs for the treatment of patients with rare, severe, and debilitating neuromuscular diseases. Scholar Rock Holding Corporation was founded in 2012 and is headquartered in Cambridge, Massachusetts.
Long Name Scholar Rock Holding Corporation
Market us_market
Market Cap 5,491,411,968
Market State PRE
Max Age 86,400
Message Board Id finmb_548810128
Most Recent Quarter 1,767,139,200
Net Income To Common -377,939,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,490,263,157
Number Of Analyst Opinions 14
Open 49.66
Operating Cashflow -300,035,008
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 857 259 3860
Pre Market Change 1.1100006
Pre Market Change Percent 2.322177
Pre Market Price 48.91
Pre Market Time 1,776,777,607
Previous Close 49.96
Price Eps Current Year -15.839038
Price Hint 2
Price To Book 21.122404
Profit Margins 0.0
Quick Ratio 6.683
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.1875
Region US
Regular Market Change -2.16
Regular Market Change Percent -4.32346
Regular Market Day High 49.69
Regular Market Day Low 47.7
Regular Market Day Range 47.7 - 49.69
Regular Market Open 49.66
Regular Market Previous Close 49.96
Regular Market Price 47.8
Regular Market Time 1,776,715,200
Regular Market Volume 1,097,392
Return On Assets -0.54687
Return On Equity -1.23083
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 114,883,096
Shares Percent Shares Out 0.137
Shares Short 15,736,891
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 14,518,252
Short Name Scholar Rock Holding Corporatio
Short Percent Of Float 0.21370001
Short Ratio 8.76
Source Interval 15
State MA
Symbol SRRK
Target High Price 70.0
Target Low Price 48.0
Target Mean Price 57.42857
Target Median Price 58.0
Total Cash 367,563,008
Total Cash Per Share 3.199
Total Debt 108,915,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.29
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 39.73115
Two Hundred Day Average Change 8.068848
Two Hundred Day Average Change Percent 0.20308618
Type Disp Equity
Volume 1,097,392
Website https://www.scholarrock.com
Zip 2,142