Seaport Therapeutics, Inc. (SPTX)Healthcare | Biotechnology | Boston, United States | NasdaqGS
24.04 USD
-2.21
(-8.419%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 24.04 |
Hot Take ↕ | Aug. 22, 2026, 3:04 a.m. EDT
The immediate outlook is driven by a powerful post-IPO momentum surge. Following a significant 17% price jump on its Nasdaq debut and an upsized IPO that raised $255 million, the stock has rallied approximately 16% over the last two months, trading well above its 50-day moving average. This technical strength suggests a high-conviction entry is developing for the near term as the market digests the fresh capital and initial sentiment. However, the long-term picture remains fundamentally opaque due to the lack of historical price data; without a multi-year track record to assess business quality or valuation stability, the investment thesis relies entirely on future clinical results rather than proven performance. Furthermore, the company is a pure-play biotech with negative earnings and no dividend history, making it unsuitable for income investors and exposing shareholders to significant volatility until the next major catalyst. |
| Model | MAE |
|---|---|
| AutoTheta ✓ | 0.061570 |
| AutoETS | 0.095296 |
| MSTL | 0.097667 |
| AutoARIMA | 0.122093 |
Forecast horizon: 45 days | Selected: AutoTheta
| Forecast Reliability | |
|---|---|
| Score | 41% |
| H-stat | 0.72 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.604 |
| Excess Kurtosis | -0.73 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 1.187 |
| Market Cap | 1,286,874,496 |
| Forward P/E | -9.34 |
| Website | https://www.seaporttx.com |
| Attribute | Value |
|---|---|
| 52 Week Change | 0.21169353 |
| Address1 | 101 Seaport Blvd. |
| Address2 | Floor 12 |
| All Time High | 28.38 |
| All Time Low | 14.85 |
| Ask | 31.61 |
| Ask Size | 2 |
| Average Analyst Rating | 1.4 - Strong Buy |
| Average Daily Volume10 Day | 123,490 |
| Average Daily Volume3 Month | 161,936 |
| Average Volume | 161,936 |
| Average Volume10Days | 123,490 |
| Bid | 18.62 |
| Bid Size | 2 |
| Book Value | -44.549 |
| City | Boston |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 24.04 |
| Current Ratio | 18.003 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 26.865 |
| Day Low | 24.04 |
| Debt To Equity | 1.187 |
| Display Name | Seaport Therapeutics |
| Ebitda | -143,751,008 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -7.086 |
| Enterprise Value | 1,018,581,440 |
| Eps Current Year | -5.90027 |
| Eps Forward | -2.57328 |
| Eps Trailing Twelve Months | -2.31 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 21.7608 |
| Fifty Day Average Change | 2.2792015 |
| Fifty Day Average Change Percent | 0.10473887 |
| Fifty Two Week Change Percent | 21.169353 |
| Fifty Two Week High | 28.38 |
| Fifty Two Week High Change | -4.3399982 |
| Fifty Two Week High Change Percent | -0.15292454 |
| Fifty Two Week Low | 14.85 |
| Fifty Two Week Low Change | 9.190001 |
| Fifty Two Week Low Change Percent | 0.61885524 |
| Fifty Two Week Range | 14.85 - 28.38 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,777,642,200,000 |
| Float Shares | 18,434,316 |
| Forward Eps | -2.57328 |
| Forward P E | -9.342162 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 58 |
| Fullday Change | -2.21 |
| Fullday Change Percent | -8.41904 |
| Fullday Price | 24.04 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 0.0 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.35081002 |
| Held Percent Institutions | 0.70595 |
| Implied Shares Outstanding | 53,530,550 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,026-05-01 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. It is leveraging its proprietary Glyph platform to advance a pipeline of therapies to address the unmet needs in depression and anxiety. The company's lead product candidate, GlyphAllo (SPT-300 or Glyph Allopregnanolone), is a novel, Glyphed oral prodrug of allopregnanolone, an endogenous molecule that has been clinically validated in third-party trials for the treatment of postpartum depression. Its second product candidate, GlyphAgo (SPT-320 or Glyph Agomelatine), is a novel, Glyphed oral prodrug of agomelatine, a clinically validated anxiolytic and antidepressant that is approved for the treatment of generalized anxiety disorder in Australia and major depressive disorder in Australia and the European Union. The company was founded in 2024 and is based in Boston, Massachusetts. |
| Long Name | Seaport Therapeutics, Inc. |
| Market | us_market |
| Market Cap | 1,286,874,496 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_1877598160 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -134,687,008 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,401,965,104 |
| Number Of Analyst Opinions | 6 |
| Open | 26.2 |
| Operating Cashflow | -88,725,000 |
| Operating Margins | 0.0 |
| Payout Ratio | 0.0 |
| Phone | (617) 807-4062 |
| Post Market Change | 0.0 |
| Post Market Change Percent | 0.0 |
| Post Market Price | 24.04 |
| Post Market Time | 1,787,959,806 |
| Previous Close | 26.25 |
| Price Eps Current Year | -4.07439 |
| Price Hint | 2 |
| Price To Book | -0.53963053 |
| Profit Margins | 0.0 |
| Quick Ratio | 17.747 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.42857 |
| Region | US |
| Regular Market Change | -2.21 |
| Regular Market Change Percent | -8.41904 |
| Regular Market Day High | 26.865 |
| Regular Market Day Low | 24.04 |
| Regular Market Day Range | 24.04 - 26.865 |
| Regular Market Open | 26.2 |
| Regular Market Previous Close | 26.25 |
| Regular Market Price | 24.04 |
| Regular Market Time | 1,787,947,200 |
| Regular Market Volume | 144,826 |
| Sand P52 Week Change | 0.20204377 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 53,530,550 |
| Shares Percent Shares Out | 0.0563 |
| Shares Short | 3,012,877 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 1,980,276 |
| Short Name | Seaport Therapeutics, Inc. |
| Short Percent Of Float | 0.0592 |
| Short Ratio | 27.05 |
| Source Interval | 15 |
| State | MA |
| Symbol | SPTX |
| Target High Price | 50.0 |
| Target Low Price | 30.0 |
| Target Mean Price | 37.0 |
| Target Median Price | 35.0 |
| Total Cash | 273,308,992 |
| Total Cash Per Share | 5.106 |
| Total Debt | 5,016,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -2.31 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 19.878313 |
| Two Hundred Day Average Change | 4.161688 |
| Two Hundred Day Average Change Percent | 0.2093582 |
| Type Disp | Equity |
| Volume | 144,826 |
| Website | https://www.seaporttx.com |
| Zip | 02,210-2186 |