| Indicators | Browse All

Seaport Therapeutics, Inc. (SPTX)

Healthcare | Biotechnology | Boston, United States | NasdaqGS
16.68 USD +0.60 (3.731%) ⇧ (Oct. 14, 2026, 4 p.m. EDT)

Short-term:★★☆☆☆Long-term:★★☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 10:59 a.m. EDT

The immediate outlook is bearish due to a severe technical breakdown; the stock has lost nearly 20% from its 50-day moving average and is trading well below its 200-day line, indicating significant downward pressure despite the recent IPO pop. While the balance sheet appears pristine with massive cash reserves and negligible debt, the company is burning cash aggressively with negative operating cash flow, which is typical for biotech but risky without imminent catalysts. The lack of any dividend history confirms this is a pure growth/speculative play. The recent 17% jump on IPO day was followed by a steady grind lower, suggesting the initial hype has cooled and the market is re-evaluating the valuation at these lower levels. Without a clear path to profitability or a major clinical milestone, the risk-reward profile remains skewed against the buyer in the near term.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.072457
MSTL0.090671
AutoETS0.091640
AutoARIMA0.094483

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 38%
H-stat 2.17
Ljung-Box p 0.000
Jarque-Bera p 0.666
Excess Kurtosis -0.35
Attribute Value
Sector Healthcare
Debt to Equity Ratio 1.187
Market Cap 892,889,600
Forward P/E -6.62
Website https://www.seaporttx.com

Info Dump

Attribute Value
52 Week Change -0.15927422
Address1 101 Seaport Blvd.
Address2 Floor 12
All Time High 28.38
All Time Low 14.85
Ask 16.16
Ask Size 1
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 216,410
Average Daily Volume3 Month 186,484
Average Volume 186,484
Average Volume10Days 216,410
Bid 12.14
Bid Size 2
Book Value 7.895
City Boston
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 16.68
Current Ratio 18.003
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 16.96
Day Low 15.83
Debt To Equity 1.187
Display Name Seaport Therapeutics
Dividend Yield 0.0
Earnings Timestamp End 1,794,486,600
Earnings Timestamp Start 1,794,486,600
Ebitda -143,751,008
Ebitda Margins 0.0
Enterprise To Ebitda -4.345
Enterprise Value 624,596,544
Eps Current Year -5.59452
Eps Forward -2.52138
Eps Trailing Twelve Months -6.03
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 22.1042
Fifty Day Average Change -5.4242
Fifty Day Average Change Percent -0.24539228
Fifty Two Week Change Percent -15.927422
Fifty Two Week High 28.38
Fifty Two Week High Change -11.699999
Fifty Two Week High Change Percent -0.41226214
Fifty Two Week Low 14.85
Fifty Two Week Low Change 1.8299999
Fifty Two Week Low Change Percent 0.12323231
Fifty Two Week Range 14.85 - 28.38
Financial Currency USD
First Trade Date Milliseconds 1,777,642,200,000
Float Shares 18,434,316
Forward Eps -2.52138
Forward P E -6.615425
Full Exchange Name NasdaqGS
Full Time Employees 58
Fullday Change 0.6000004
Fullday Change Percent 3.7313457
Fullday Price 16.68
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.35143003
Held Percent Institutions 0.70988
Implied Shares Outstanding 53,530,550
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,026-05-01
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Seaport Therapeutics, Inc., a clinical-stage therapeutics company, focuses on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. It is leveraging its proprietary Glyph platform to advance a pipeline of therapies to address the unmet needs in depression and anxiety. The company's lead product candidate, GlyphAllo (SPT-300 or Glyph Allopregnanolone), is a novel, Glyphed oral prodrug of allopregnanolone, an endogenous molecule that has been clinically validated in third-party trials for the treatment of postpartum depression. Its second product candidate, GlyphAgo (SPT-320 or Glyph Agomelatine), is a novel, Glyphed oral prodrug of agomelatine, a clinically validated anxiolytic and antidepressant that is approved for the treatment of generalized anxiety disorder in Australia and major depressive disorder in Australia and the European Union. The company was founded in 2024 and is based in Boston, Massachusetts.
Long Name Seaport Therapeutics, Inc.
Market us_market
Market Cap 892,889,600
Market State PRE
Max Age 86,400
Message Board Id finmb_1877598160
Most Recent Quarter 1,782,777,600
Net Income To Common -134,687,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,139,665,409
Number Of Analyst Opinions 8
Open 15.98
Operating Cashflow -88,725,000
Operating Margins 0.0
Phone (617) 807-4062
Previous Close 16.08
Price Eps Current Year -2.981489
Price Hint 2
Price To Book 2.1127295
Profit Margins 0.0
Quick Ratio 17.747
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.375
Region US
Regular Market Change 0.6000004
Regular Market Change Percent 3.7313457
Regular Market Day High 16.96
Regular Market Day Low 15.83
Regular Market Day Range 15.83 - 16.96
Regular Market Open 15.98
Regular Market Previous Close 16.08
Regular Market Price 16.68
Regular Market Time 1,792,008,001
Regular Market Volume 208,622
Sand P52 Week Change 0.16440773
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 53,530,550
Shares Percent Shares Out 0.0682
Shares Short 3,649,879
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 3,152,409
Short Name Seaport Therapeutics, Inc.
Short Percent Of Float 0.0717
Short Ratio 12.95
Source Interval 15
State MA
Symbol SPTX
Target High Price 50.0
Target Low Price 28.0
Target Mean Price 37.0
Target Median Price 35.0
Total Cash 273,308,992
Total Cash Per Share 5.106
Total Debt 5,016,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -6.03
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 20.171913
Two Hundred Day Average Change -3.4919128
Two Hundred Day Average Change Percent -0.17310767
Type Disp Equity
Volume 208,622
Website https://www.seaporttx.com
Zip 02,210-2186