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Seaport Therapeutics, Inc. (SPTX)

Healthcare | Biotechnology | Boston, United States | NasdaqGS
18.19 USD -0.61 (-3.245%) ⇩ (May 29, 2026, 4 p.m. EDT)
After hours: 18.66 +0.47 (2.584%) ⇧ (May 29, 2026, 5:12 p.m. EDT)

Short-term:★★⯪☆☆Long-term:☆☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | May 25, 2026, 3:12 a.m. EDT

The immediate catalyst here is the recent pricing of an upsized IPO, which injected significant capital and pushed the share price up from the lows, creating a temporary pop. However, looking past the initial offering hype, the underlying business presents a severe value trap. The company is burning through cash rapidly, with negative free cash flow and operating cash flow, while holding negative book value and reporting losses on both assets and equity. There is no dividend to provide income, and the lack of any price history since the IPO debut makes assessing a multi-year growth trajectory impossible. While the stock is currently trading near its 52-week highs relative to the post-IPO floor, the fundamental reality is a pre-revenue biotech firm with no earnings power and a balance sheet that requires constant dilution or cash infusion to survive. This is not a buy-and-hold opportunity; it is a speculative gamble on future clinical trials rather than an investment in a profitable enterprise.

None
Attribute Value
Sector Healthcare
Market Cap 964,576,000
Forward P/E -7.52
Website https://www.seaporttx.com

Info Dump

Attribute Value
52 Week Change -0.052419364
Address1 101 Seaport Blvd.
Address2 Floor 12
All Time High 23.0
All Time Low 14.85
Ask 18.94
Ask Size 1
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 287,930
Average Daily Volume3 Month 610,473
Average Volume 610,473
Average Volume10Days 287,930
Bid 18.17
Bid Size 1
Book Value -11.354
City Boston
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 18.19
Current Ratio 17.464
Custom Price Alert Confidence HIGH
Date Short Interest 1,778,803,200
Day High 18.6759
Day Low 17.84
Display Name Seaport Therapeutics
Ebitda -85,223,000
Ebitda Margins 0.0
Eps Current Year -3.25292
Eps Forward -2.41956
Eps Trailing Twelve Months -1.94
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 16.766842
Fifty Day Average Change 1.4231586
Fifty Day Average Change Percent 0.08487935
Fifty Two Week Change Percent -5.2419367
Fifty Two Week High 23.0
Fifty Two Week High Change -4.8099995
Fifty Two Week High Change Percent -0.2091304
Fifty Two Week Low 14.85
Fifty Two Week Low Change 3.3400002
Fifty Two Week Low Change Percent 0.22491583
Fifty Two Week Range 14.85 - 23.0
First Trade Date Milliseconds 1,777,642,200,000
Float Shares 2,892,698
Forward Eps -2.41956
Forward P E -7.517896
Free Cashflow -50,781,500
Full Exchange Name NasdaqGS
Full Time Employees 58
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.35388002
Held Percent Institutions 0.28642
Implied Shares Outstanding 53,027,817
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,026-05-01
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Seaport Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company advancing the development of novel neuropsychiatric medicines. The company develops therapeutic candidates for conditions such as depression and anxiety disorders using its proprietary Glyph technology platform. The Glyph platform is designed to enable oral bioavailability, bypass first-pass metabolism, and reduce liver enzyme elevations or hepatotoxicity and other side effects. All therapeutic candidates in development are based on this platform, with research and development activities focused on neuropsychiatric medicines. The company serves clinicians and key opinion leaders in the healthcare and neuropsychiatric medicine sectors. The company was founded in 2024 and is based in Boston, Massachusetts.
Long Name Seaport Therapeutics, Inc.
Market us_market
Market Cap 964,576,000
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_1877598160
Net Income To Common -74,881,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 996,922,959
Number Of Analyst Opinions 4
Open 18.61
Operating Cashflow -77,942,000
Operating Margins 0.0
Payout Ratio 0.0
Phone (617) 807-4062
Post Market Change 0.4699993
Post Market Change Percent 2.5838335
Post Market Price 18.66
Post Market Time 1,780,089,139
Previous Close 18.8
Price Eps Current Year -5.5918994
Price Hint 2
Price To Book -1.6020786
Profit Margins 0.0
Quick Ratio 17.134
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.609999
Regular Market Change Percent -3.24467
Regular Market Day High 18.6759
Regular Market Day Low 17.84
Regular Market Day Range 17.84 - 18.6759
Regular Market Open 18.61
Regular Market Previous Close 18.8
Regular Market Price 18.19
Regular Market Time 1,780,084,800
Regular Market Volume 112,112
Return On Assets -0.189
Return On Equity -0.28084
Sand P52 Week Change 0.2794361
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 53,027,817
Shares Percent Shares Out 0.0275
Shares Short 1,459,469
Short Name Seaport Therapeutics, Inc.
Short Percent Of Float 0.028900001
Short Ratio 1.65
Source Interval 15
State MA
Symbol SPTX
Target High Price 42.0
Target Low Price 30.0
Target Mean Price 35.5
Target Median Price 35.0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.94
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 16.766842
Two Hundred Day Average Change 1.4231586
Two Hundred Day Average Change Percent 0.08487935
Type Disp Equity
Volume 112,112
Website https://www.seaporttx.com
Zip 02,210-2186