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Senti Biosciences Holdings, Inc. (SNTI)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqCM
0.96 USD -0.07 (-6.796%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5 a.m. EDT

The immediate outlook is severely clouded by a relentless multi-year price collapse and deteriorating fundamentals. While the stock recently traded near $1.03, the underlying business has suffered a catastrophic structural decline, losing nearly 98% of its value over the last four years with every single year showing negative growth. This is not a temporary setback; the company is burning through massive cash reserves with negative operating cash flow and no revenue, while carrying significant debt against a tiny book value. The recent corporate reorganization adds complexity without addressing the core solvency issues. With no dividend to provide income and a balance sheet that appears fragile relative to its obligations, there is no margin of safety here. The statistical models offer no help, predicting flat movement with low confidence, which aligns with the reality that the market has already priced in a lack of survival probability. Avoid this security entirely.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.068778
AutoETS0.076850
MSTL_1150.090342
AutoARIMA0.186901
AutoTheta0.187732

Forecast horizon: 60 days | Selected: MSTL

Forecast Reliability
Score 33%
H-stat 1.02
Ljung-Box p 0.000
Jarque-Bera p 0.197
Excess Kurtosis -0.56
Attribute Value
Sector Healthcare
Debt to Equity Ratio 746.238
Revenue per Share 0.001
Market Cap 29,898,964
Forward P/E -1.01
Beta 2.05
Previous Name Senti Biosciences, Inc.
Website https://www.sentibio.com

Info Dump

Attribute Value
52 Week Change -0.47715735
Address1 2 Corporate Drive
Address2 First Floor
All Time High 105.4
All Time Low 0.77
Ask 1.23
Ask Size 2
Average Daily Volume10 Day 124,320
Average Daily Volume3 Month 204,014
Average Volume 204,014
Average Volume10Days 124,320
Beta 2.052
Bid 0.7059
Bid Size 2
Book Value 0.082
City South San Francisco
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.96
Current Ratio 1.037
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 1.025
Day Low 0.96
Debt To Equity 746.238
Display Name Senti Biosciences
Earnings Timestamp End 1,755,547,260
Earnings Timestamp Start 1,755,115,260
Ebitda -51,639,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.773
Enterprise To Revenue 1,050.341
Enterprise Value 39,912,964
Eps Current Year -1.15667
Eps Forward -0.95
Eps Trailing Twelve Months -1.46
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.99146
Fifty Day Average Change -0.031460047
Fifty Day Average Change Percent -0.031731028
Fifty Two Week Change Percent -47.715736
Fifty Two Week High 2.88
Fifty Two Week High Change -1.9200001
Fifty Two Week High Change Percent -0.6666667
Fifty Two Week Low 0.77
Fifty Two Week Low Change 0.19
Fifty Two Week Low Change Percent 0.24675325
Fifty Two Week Range 0.77 - 2.88
Financial Currency USD
First Trade Date Milliseconds 1,622,035,800,000
Float Shares 12,448,558
Forward Eps -0.95
Forward P E -1.0105263
Free Cashflow -17,241,750
Full Exchange Name NasdaqCM
Full Time Employees 39
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -37,581,000
Has Pre Post Market Data 1
Held Percent Insiders 0.47907
Held Percent Institutions 0.18535
Implied Shares Outstanding 31,144,754
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,721,260,800
Last Split Factor 1:10
Long Business Summary Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company's lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc. and changed its name to Senti Biosciences Holdings, Inc. in April 2026. The company was incorporated in 2016 and is headquartered in South San Francisco, California.
Long Name Senti Biosciences Holdings, Inc.
Market us_market
Market Cap 29,898,964
Market State PRE
Max Age 86,400
Message Board Id finmb_538838857
Most Recent Quarter 1,774,915,200
Name Change Date 2,026-07-13
Net Income To Common -51,547,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 32,079,096
Number Of Analyst Opinions 3
Open 0.9974
Operating Cashflow -36,875,000
Operating Margins -713.625
Payout Ratio 0.0
Phone 650 239 2030
Pre Market Change 0.03430003
Pre Market Change Percent 3.5729198
Pre Market Price 0.9943
Pre Market Time 1,784,016,016
Prev Name Senti Biosciences, Inc.
Previous Close 1.03
Price Eps Current Year -0.8299688
Price Hint 4
Price To Book 11.707316
Price To Sales Trailing12 Months 786.8148
Profit Margins 0.0
Quick Ratio 0.693
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.07
Regular Market Change Percent -6.79612
Regular Market Day High 1.025
Regular Market Day Low 0.96
Regular Market Day Range 0.96 - 1.025
Regular Market Open 0.9974
Regular Market Previous Close 1.03
Regular Market Price 0.96
Regular Market Time 1,783,972,800
Regular Market Volume 103,139
Return On Assets -0.56848997
Return On Equity -2.55032
Revenue Per Share 0.001
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 31,144,754
Shares Percent Shares Out 0.0174
Shares Short 542,766
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 569,020
Short Name Senti Biosciences Holdings, Inc
Short Percent Of Float 0.0312
Short Ratio 2.86
Source Interval 15
State CA
Symbol SNTI
Target High Price 15.0
Target Low Price 12.0
Target Mean Price 13.0
Target Median Price 12.0
Total Cash 9,127,000
Total Cash Per Share 0.293
Total Debt 19,141,000
Total Revenue 38,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.46
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.24252
Two Hundred Day Average Change -0.28252
Two Hundred Day Average Change Percent -0.22737662
Type Disp Equity
Volume 103,139
Website https://www.sentibio.com
Zip 94,080