Senti Biosciences Holdings, Inc. (SNTI)Healthcare | Biotechnology | South San Francisco, United States | NasdaqCM
0.38 USD
0.00
(-0.132%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 0.39 +0.02 (4.668%) ⇧ (Aug. 28, 2026, 7:59 p.m. EDT) |
Hot Take ↕ | Aug. 22, 2026, 4:29 a.m. EDT
The immediate outlook is severely bearish as the stock trades at a fraction of its value, having lost nearly 98% of its worth over the last four years. While the recent price action shows a brief, volatile bounce off the lows, the underlying reality is stark: the company is burning through cash at an alarming rate with negative operating margins exceeding 790%, massive debt obligations, and no revenue to speak of. The balance sheet is fragile, with current liabilities outweighing current assets, and the management team is engaged in complex restructuring maneuvers including reverse splits and mergers, which often signal distress rather than growth. There is no dividend to provide income, and the lack of any profitable history or sustainable business model makes a long-term hold a dangerous proposition. The disconnect between the lofty analyst price targets and the actual financial fundamentals suggests a speculative bubble that has likely already burst. |
| Model | MAE |
|---|---|
| AutoTheta ✓ | 0.534262 |
| AutoETS | 0.565588 |
| MSTL | 0.570360 |
| AutoARIMA | 0.571499 |
Forecast horizon: 45 days | Selected: AutoTheta
| Forecast Reliability | |
|---|---|
| Score | 26% |
| H-stat | 46.16 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.039 |
| Excess Kurtosis | -1.68 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Revenue per Share | 0.002 |
| Market Cap | 11,741,572 |
| Forward P/E | -0.40 |
| Beta | 2.11 |
| Previous Name | Senti Biosciences, Inc. |
| Website | https://www.sentibio.com |
| Attribute | Value |
|---|---|
| 52 Week Change | -0.73566437 |
| Address1 | 2 Corporate Drive |
| Address2 | First Floor |
| All Time High | 105.4 |
| All Time Low | 0.331 |
| Ask | 0.4872 |
| Ask Size | 2 |
| Average Daily Volume10 Day | 330,520 |
| Average Daily Volume3 Month | 265,459 |
| Average Volume | 265,459 |
| Average Volume10Days | 330,520 |
| Beta | 2.108 |
| Bid | 0.2676 |
| Bid Size | 2 |
| Book Value | -0.109 |
| City | South San Francisco |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 0.377 |
| Current Ratio | 0.825 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 0.398 |
| Day Low | 0.3655 |
| Display Name | Senti Biosciences |
| Earnings Timestamp End | 1,755,547,260 |
| Earnings Timestamp Start | 1,755,115,260 |
| Ebitda | -50,167,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -0.506 |
| Enterprise To Revenue | 461.101 |
| Enterprise Value | 25,360,572 |
| Eps Current Year | -1.045 |
| Eps Forward | -0.95 |
| Eps Trailing Twelve Months | -1.64 |
| Esg Populated | 0 |
| Exchange | NCM |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 0.62674 |
| Fifty Day Average Change | -0.24973997 |
| Fifty Day Average Change Percent | -0.39847463 |
| Fifty Two Week Change Percent | -73.56644 |
| Fifty Two Week High | 2.88 |
| Fifty Two Week High Change | -2.503 |
| Fifty Two Week High Change Percent | -0.8690972 |
| Fifty Two Week Low | 0.331 |
| Fifty Two Week Low Change | 0.046000004 |
| Fifty Two Week Low Change Percent | 0.13897282 |
| Fifty Two Week Range | 0.331 - 2.88 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,622,035,800,000 |
| Float Shares | 12,284,114 |
| Forward Eps | -0.95 |
| Forward P E | -0.39684212 |
| Free Cashflow | -17,112,376 |
| Full Exchange Name | NasdaqCM |
| Full Time Employees | 39 |
| Fullday Change | -0.000499994 |
| Fullday Change Percent | -0.132449 |
| Fullday Price | 0.3946 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 0.0 |
| Gross Profits | -31,269,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.47907 |
| Held Percent Institutions | 0.18997999 |
| Implied Shares Outstanding | 31,144,754 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Last Split Date | 1,721,260,800 |
| Last Split Factor | 1:10 |
| Long Business Summary | Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company's lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc. and changed its name to Senti Biosciences Holdings, Inc. in April 2026. The company was incorporated in 2016 and is headquartered in South San Francisco, California. |
| Long Name | Senti Biosciences Holdings, Inc. |
| Market | us_market |
| Market Cap | 11,741,572 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_538838857 |
| Most Recent Quarter | 1,782,777,600 |
| Name Change Date | 2,026-08-28 |
| Net Income To Common | -49,564,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 11,872,380 |
| Number Of Analyst Opinions | 2 |
| Open | 0.3904 |
| Operating Cashflow | -38,051,000 |
| Operating Margins | -793.7059 |
| Payout Ratio | 0.0 |
| Phone | 650 239 2030 |
| Post Market Change | 0.0176 |
| Post Market Change Percent | 4.668435 |
| Post Market Price | 0.3946 |
| Post Market Time | 1,787,961,547 |
| Prev Name | Senti Biosciences, Inc. |
| Previous Close | 0.3775 |
| Price Eps Current Year | -0.36076558 |
| Price Hint | 4 |
| Price To Book | -3.4587157 |
| Price To Sales Trailing12 Months | 213.48312 |
| Profit Margins | 0.0 |
| Quick Ratio | 0.454 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.000499994 |
| Regular Market Change Percent | -0.132449 |
| Regular Market Day High | 0.398 |
| Regular Market Day Low | 0.3655 |
| Regular Market Day Range | 0.3655 - 0.398 |
| Regular Market Open | 0.3904 |
| Regular Market Previous Close | 0.3775 |
| Regular Market Price | 0.377 |
| Regular Market Time | 1,787,947,201 |
| Regular Market Volume | 90,812 |
| Return On Assets | -0.65569997 |
| Return On Equity | -4.66463 |
| Revenue Per Share | 0.002 |
| Sand P52 Week Change | 0.20504117 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 31,144,754 |
| Shares Percent Shares Out | 0.0167 |
| Shares Short | 519,649 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 605,050 |
| Short Name | Senti Biosciences Holdings, Inc |
| Short Percent Of Float | 0.0299 |
| Short Ratio | 1.41 |
| Source Interval | 15 |
| State | CA |
| Symbol | SNTI |
| Target High Price | 15.0 |
| Target Low Price | 12.0 |
| Target Mean Price | 13.5 |
| Target Median Price | 13.5 |
| Total Cash | 6,607,000 |
| Total Cash Per Share | 0.212 |
| Total Debt | 20,226,000 |
| Total Revenue | 55,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.64 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.00329 |
| Two Hundred Day Average Change | -0.6262901 |
| Two Hundred Day Average Change Percent | -0.6242363 |
| Type Disp | Equity |
| Volume | 90,812 |
| Website | https://www.sentibio.com |
| Zip | 94,080 |