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Sangamo Therapeutics, Inc. (SGMO)

Healthcare | Biotechnology | Richmond, United States | NasdaqCM
0.26 USD -0.01 (-2.963%) ⇩ (April 17, 2026, 4 p.m. EDT)
After hours: 0.27 +0.01 (3.015%) ⇧ (April 17, 2026, 7:48 p.m. EDT)

Short-term: ★☆☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:35 p.m. EDT

Despite a bullish analyst target consensus, the on-the-ground data tells a strongly bearish tale. The stock is tracking the $0.21-0.26 range, well below its $0.35 50-day average, while suffering from negative breadth and heavy options hedging in the $1.00 strike. The lack of put volume expiring in a month before the earnings date suggests speculators are 'selling the news' or exiting positions rather than setting stops. Fundamentally, with -$56M cash burn, negative operating cash flow, and a recent earnings miss, SGMO is currently a cash-burning biotech stock with no dividend support, making this a low-conviction hold at worst.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.116176
MSTL0.121969
AutoETS0.123799
AutoARIMA0.126446

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 66%
H-stat 1.50
Ljung-Box p 0.000
Jarque-Bera p 0.695
Excess Kurtosis 0.49
Attribute Value
Sector Healthcare
Revenue per Share 0.141
Market Cap 108,539,792
Forward P/E Infinity
Beta 1.50
Website https://www.sangamo.com

As of April 18, 2026, 10:35 p.m. EDT: Options flow indicates aggressive positioning for downside protection. In the near term (April expiration), Put OI is effectively zero, suggesting limited hedging pressure for the immediate launch week, but Call volume is heavily concentrated in ATM strikes (0.5 strike). Longer-term expirations show significant volume and Open Interest in ITM puts (Jan 2707 strike), specifically the $1.00 strike which has high OI relative to volatility, signaling a 'black swan' hedge or settlement guarantee below current levels. The Call market is consistently out-of-the-money, suggesting speculative bets for a rebound are capped by this put barrier.


Info Dump

Attribute Value
52 Week Change -0.6486486
Address1 501 Canal Blvd
All Time High 51.375
All Time Low 0.21
Ask 0.3059
Ask Size 1
Audit Risk 7
Average Daily Volume10 Day 5,378,260
Average Daily Volume3 Month 6,866,835
Average Volume 6,866,835
Average Volume10Days 5,378,260
Beta 1.503
Bid 0.2296
Bid Size 1
Board Risk 3
Book Value -0.041
City Richmond
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.262
Current Ratio 0.844
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 0.284
Day Low 0.262
Display Name Sangamo Therapeutics
Earnings Call Timestamp End 1,774,902,600
Earnings Call Timestamp Start 1,774,902,600
Earnings Timestamp 1,774,900,800
Earnings Timestamp End 1,778,529,600
Earnings Timestamp Start 1,778,529,600
Ebitda -104,043,000
Ebitda Margins -2.63054
Enterprise To Ebitda -1.099
Enterprise To Revenue 2.892
Enterprise Value 114,386,792
Eps Current Year -0.26
Eps Forward 0.0
Eps Trailing Twelve Months -0.44
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.352
Fifty Day Average Change -0.09
Fifty Day Average Change Percent -0.25568184
Fifty Two Week Change Percent -64.86486
Fifty Two Week High 0.84
Fifty Two Week High Change -0.57799995
Fifty Two Week High Change Percent -0.6880952
Fifty Two Week Low 0.21
Fifty Two Week Low Change 0.052
Fifty Two Week Low Change Percent 0.24761906
Fifty Two Week Range 0.21 - 0.84
Financial Currency USD
First Trade Date Milliseconds 955,027,800,000
Float Shares 406,771,515
Forward Eps 0.0
Forward P E Infinity
Free Cashflow -56,760,500
Full Exchange Name NasdaqCM
Full Time Employees 142
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins -1.8486501
Gross Profits -73,118,000
Has Pre Post Market Data 1
Held Percent Insiders 0.01741
Held Percent Institutions 0.15325
Implied Shares Outstanding 414,274,017
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Sangamo Therapeutics, Inc., a clinical-stage genomic medicine company, focuses on translating science into medicines that transform the lives of patients and families afflicted with serious diseases in the United States. The company's clinical-stage product candidates are ST-920, a gene therapy product candidate, which is in Phase 1/2 clinical study for the treatment of Fabry disease; TX200, a chimeric antigen receptor engineered regulatory T cell (CAR-Treg) therapy product candidate that is in Phase 1/2 clinical study for the prevention of immune-mediated rejection in HLA-A2 mismatched kidney transplantation; and SB-525, a gene therapy product candidate, which is in Phase 3 clinical trial for the treatment of moderately severe to severe hemophilia A. Its preclinical development products focus on tauopathies, ALS/FTD, and huntington's diseases Sangamo Therapeutics, Inc. has collaborative and strategic partnerships with Biogen MA, Inc.; Kite Pharma, Inc.; Pfizer Inc.; Sanofi S.A.; Novartis Institutes for BioMedical Research, Inc.; Shire International GmbH; Dow AgroSciences LLC; Sigma-Aldrich Corporation; Genentech, Inc.; and Open Monoclonal Technology, Inc. The company was formerly known as Sangamo BioSciences, Inc. and changed its name to Sangamo Therapeutics, Inc. in January 2017. The company was incorporated in 1995 and is headquartered in Richmond, California.
Long Name Sangamo Therapeutics, Inc.
Market us_market
Market Cap 108,539,792
Market State CLOSED
Max Age 86,400
Message Board Id finmb_412674
Most Recent Quarter 1,767,139,200
Net Income To Common -122,932,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 108,539,792
Number Of Analyst Opinions 4
Open 0.2759
Operating Cashflow -97,208,000
Operating Margins -1.75485
Overall Risk 4
Payout Ratio 0.0
Phone 510 970 6000
Post Market Change 0.0079
Post Market Change Percent 3.0152671
Post Market Price 0.2699
Post Market Time 1,776,469,730
Previous Close 0.27
Price Eps Current Year -1.0076923
Price Hint 4
Price To Book -6.3902435
Price To Sales Trailing12 Months 2.7442303
Profit Margins 0.0
Quick Ratio 0.741
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.00800002
Regular Market Change Percent -2.96297
Regular Market Day High 0.284
Regular Market Day Low 0.262
Regular Market Day Range 0.262 - 0.284
Regular Market Open 0.2759
Regular Market Previous Close 0.27
Regular Market Price 0.262
Regular Market Time 1,776,456,000
Regular Market Volume 3,104,485
Return On Assets -0.83656996
Return On Equity -28.91837
Revenue Growth 0.884
Revenue Per Share 0.141
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 2
Shares Outstanding 414,274,017
Shares Percent Shares Out 0.0908
Shares Short 37,605,702
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 33,065,989
Short Name Sangamo Therapeutics, Inc.
Short Percent Of Float 0.091400005
Short Ratio 6.15
Source Interval 15
State CA
Symbol SGMO
Target High Price 10.0
Target Low Price 1.0
Target Mean Price 3.75
Target Median Price 2.0
Total Cash 20,948,000
Total Cash Per Share 0.051
Total Debt 26,795,000
Total Revenue 39,552,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.44
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 0.47675
Two Hundred Day Average Change -0.21474999
Two Hundred Day Average Change Percent -0.4504457
Type Disp Equity
Volume 3,104,485
Website https://www.sangamo.com
Zip 94,804