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Serina Therapeutics, Inc. (SER)

Healthcare | Biotechnology | Huntsville, United States | NYSE American
2.46 USD -0.06 (-2.381%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 2.40 -0.06 (-0.060%) ⇩ (Aug. 28, 2026, 7:48 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4 a.m. EDT

The immediate outlook is neutral-to-slightly-bearish despite a recent bounce; the stock has rallied from its lows but remains trapped beneath key moving averages, and the statistical forecast model offers virtually no directional guidance due to extremely low reliability. Fundamentally, this is a distressed biotech play with severe structural damage: the business has lost over 94% of its value over the last six years, with the last two full years showing double-digit declines. While the company recently reported first-quarter results and a director made a small purchase, these are insufficient to counteract the massive capital burn, negative returns on equity, and lack of profitability. With no dividend to provide income and a balance sheet that suggests ongoing distress rather than a fortress, the investment case relies entirely on a speculative turnaround in its Parkinson's trials, which currently carries significant risk.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.160175
MSTL0.165008
AutoETS0.165247
AutoTheta0.197399

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 24%
H-stat 18.67
Ljung-Box p 0.000
Jarque-Bera p 0.002
Excess Kurtosis 0.67
Attribute Value
Sector Healthcare
Debt to Equity Ratio 20.043
Market Cap 62,485,164
Forward P/E -2.34
Beta 0.00
Website https://serinatherapeutics.com

Info Dump

Attribute Value
52 Week Change -0.52542377
Address1 601 Genome Way
Address2 Suite 2001
All Time High 212.5
All Time Low 1.22
Ask 2.49
Ask Size 100
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 59,930
Average Daily Volume3 Month 79,066
Average Volume 79,066
Average Volume10Days 59,930
Beta -0.003
Bid 2.44
Bid Size 100
Book Value 0.737
City Huntsville
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.46
Current Ratio 6.653
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 2.5299
Day Low 2.44
Debt To Equity 20.043
Display Name Serina Therapeutics
Earnings Timestamp End 1,754,654,400
Earnings Timestamp Start 1,754,305,140
Ebitda -25,587,000
Ebitda Margins 0.0
Enterprise To Ebitda -1.689
Enterprise Value 43,215,164
Eps Current Year -1.41
Eps Forward -1.05
Eps Trailing Twelve Months -1.83
Esg Populated 0
Exchange ASE
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.2384
Fifty Day Average Change 0.22160006
Fifty Day Average Change Percent 0.098999314
Fifty Two Week Change Percent -52.542377
Fifty Two Week High 5.83
Fifty Two Week High Change -3.37
Fifty Two Week High Change Percent -0.5780446
Fifty Two Week Low 1.22
Fifty Two Week Low Change 1.24
Fifty Two Week Low Change Percent 1.0163934
Fifty Two Week Range 1.22 - 5.83
Financial Currency USD
First Trade Date Milliseconds 1,543,501,800,000
Float Shares 11,148,014
Forward Eps -1.05
Forward P E -2.3428574
Free Cashflow -12,350,875
Full Exchange Name NYSE American
Full Time Employees 16
Fullday Change -0.0599999
Fullday Change Percent -2.38095
Fullday Price 2.3999
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -14,067,000
Has Pre Post Market Data 1
Held Percent Insiders 0.50755
Held Percent Institutions 0.05547
Implied Shares Outstanding 25,400,473
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,710,460,800
Last Split Factor 28:1000
Long Business Summary Serina Therapeutics, Inc., a biotechnology company, develops drugs to treat neurological diseases and pain. Its lead product candidate is SER 252 (POZ-apomorphine), a POZ conjugate for the treatment of advanced Parkinson's disease that is in phase 1 clinical trial; and POZ-lipids, a non-immunogenic alternative to the PEG-lipids in the lipid nanoparticles. The company also develops SER 214, a POZ conjugate of rotigotine for the treatment of early Parkinson's and Restless Leg Syndrome, which has completed phase 1a clinical trial. In addition, it develops POZ technology in lipid nanoparticle delivered ribonucleic acid vaccines for infectious diseases. It has a partnership agreement with Gannet BioChem to support development activities for SER-252. Serina Therapeutics, Inc. was founded in 2006 and is headquartered in Huntsville, Alabama.
Long Name Serina Therapeutics, Inc.
Market us_market
Market Cap 62,485,164
Market State CLOSED
Max Age 86,400
Message Board Id finmb_133692495
Most Recent Quarter 1,782,777,600
Net Income To Common -23,925,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 64,009,191
Number Of Analyst Opinions 2
Open 2.52
Operating Cashflow -21,135,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 256 327 9630
Post Market Change -0.06010008
Post Market Change Percent -2.4430926
Post Market Price 2.3999
Post Market Time 1,787,960,880
Previous Close 2.52
Price Eps Current Year -1.7446809
Price Hint 4
Price To Book 3.3378563
Price To Sales Trailing12 Months Infinity
Profit Margins 0.0
Quick Ratio 6.12
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change -0.0599999
Regular Market Change Percent -2.38095
Regular Market Day High 2.5299
Regular Market Day Low 2.44
Regular Market Day Range 2.44 - 2.5299
Regular Market Open 2.52
Regular Market Previous Close 2.52
Regular Market Price 2.46
Regular Market Time 1,787,947,200
Regular Market Volume 33,832
Return On Assets -0.92300004
Return On Equity -2.0794098
Revenue Per Share 0.0
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 25,400,473
Shares Percent Shares Out 0.0057
Shares Short 145,548
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 284,546
Short Name Serina Therapeutics, Inc.
Short Percent Of Float 0.0066000004
Short Ratio 3.15
Source Interval 15
State AL
Symbol SER
Target High Price 11.0
Target Low Price 8.0
Target Mean Price 9.5
Target Median Price 9.5
Total Cash 23,024,000
Total Cash Per Share 0.906
Total Debt 3,754,000
Total Revenue 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.83
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.32592
Two Hundred Day Average Change 0.13407993
Two Hundred Day Average Change Percent 0.057645977
Type Disp Equity
Volume 33,832
Website https://serinatherapeutics.com
Zip 35,806