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ALPS Medical Breakthroughs ETF (SBIO)

Health | Exchange Traded Fund | NYSEArca
50.27 USD -1.95 (-3.734%) ⇩ (Oct. 16, 2026, 2:35 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★★☆☆Dividends:★★☆☆☆
Hot Take ↕ | Oct. 10, 2026, 3:25 a.m. EDT

The ALPS Medical Breakthroughs ETF presents a compelling case for a tactical swing trade rather than a passive hold. Fundamentally, the business quality is solid; the nine-year price trajectory shows a robust 58% cumulative gain with no recent consecutive declines, confirming that the market has consistently rewarded the sector's growth over the long term. However, the immediate setup is messy. The price has been grinding lower recently, trading well below its 50-day moving average, which suggests short-term weakness. This disconnect creates a specific opportunity: while the long-term trend remains intact, the short-term momentum is currently negative. Options data confirms this divergence. Traders are positioning aggressively for a rally, stacking massive open interest in deep out-of-the-money calls for late 2027, while ignoring downside protection. This asymmetry suggests smart money expects a catalyst to drive prices higher, even if the immediate chart looks tired. The statistical forecast model offers a modest 1.7% upside lean with moderate confidence, aligning with the bullish options flow but failing to account for the current downtrend. Regarding income, the dividend profile is weak. With only two payments recorded in the last five years totaling roughly 1.25, the yield is effectively zero. Investors here are purely seeking capital appreciation, not income. Given the strong long-term fundamentals but the current technical drag, a 3.5-star short-term rating reflects the potential for a bounce driven by the underlying thesis and options positioning, while the 3.0 long-term rating acknowledges the solid business without overstating the immediate entry point.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.096800
AutoARIMA0.096991
AutoETS0.096991
AutoTheta0.113012

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 42%
H-stat 47.66
Ljung-Box p 0.000
Jarque-Bera p 0.153
Excess Kurtosis -1.12

As of Oct. 10, 2026, 3:25 a.m. EDT: Speculators are overwhelmingly bullish, with heavy open interest concentrated in out-of-the-money calls (70 and 75 strikes) for January 2027 expirations, suggesting a bet on significant upside. Conversely, put activity is negligible and confined to lower strikes, indicating a lack of hedging demand against a crash.


Dividend Data

Dividend History
Date Dividend Yield %
2024-12-19 1.174 3.524150
2023-12-21 0.071 0.229684
2019-12-19 0.016 0.037506
2018-12-20 0.784 2.879177
2017-12-21 0.579 1.792015
Additional Data
trailingAnnualDividendRate 0.0
trailingAnnualDividendYield 0.0
dividendYield 0.0

Info Dump

Attribute Value
All Time High 70.85
All Time Low 19.18
Ask 50.19
Ask Size 4,900
Average Daily Volume10 Day 46,660
Average Daily Volume3 Month 39,895
Average Volume 39,895
Average Volume10Days 46,660
Beta3 Year 0.92
Bid 50.07
Bid Size 3,300
Category Health
Crypto Tradeable 0
Currency USD
Custom Price Alert Confidence HIGH
Day High 51.3499
Day Low 49.96
Dividend Yield 0.0
Esg Populated 0
Exchange PCX
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 62.86266
Fifty Day Average Change -12.592659
Fifty Day Average Change Percent -0.20032017
Fifty Two Week Change Percent 23.779274
Fifty Two Week High 70.85
Fifty Two Week High Change -20.579998
Fifty Two Week High Change Percent -0.2904728
Fifty Two Week Low 41.73
Fifty Two Week Low Change 8.540001
Fifty Two Week Low Change Percent 0.20464896
Fifty Two Week Range 41.73 - 70.85
First Trade Date Milliseconds 1,420,036,200,000
Five Year Average Return 0.0272019
Full Exchange Name NYSEArca
Fullday Change -1.9500008
Fullday Change Percent -3.7342029
Fullday Price 50.27
Fund Family ALPS
Fund Inception Date 1,419,897,600
Gmt Off Set Milliseconds -14,400,000
Has Pre Post Market Data 1
Language en-US
Legal Type Exchange Traded Fund
Long Business Summary The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small and mid-cap stocks of biotechnology companies that have one or more drugs in either Phase II or Phase III of the U.S. Food and Drug Administration clinical trials.
Long Name ALPS Medical Breakthroughs ETF
Market us_market
Market State REGULAR
Max Age 86,400
Message Board Id finmb_275139748
Nav Price 51.15
Net Assets 211,557,632.0
Net Expense Ratio 0.5
Open 52.22
Phone 855.724.0450
Previous Close 52.22
Price Hint 2
Quote Source Name Nasdaq Real Time Price
Quote Type ETF
Region US
Regular Market Change -1.9500008
Regular Market Change Percent -3.7342029
Regular Market Day High 51.3499
Regular Market Day Low 49.96
Regular Market Day Range 49.96 - 51.3499
Regular Market Open 52.22
Regular Market Previous Close 52.22
Regular Market Price 50.27
Regular Market Time 1,792,175,705
Regular Market Volume 18,632
Short Name ALPS Medical Breakthroughs ETF
Source Interval 15
Symbol SBIO
Three Year Average Return 0.28116542
Total Assets 211,557,632
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Peg Ratio None
Trailing Three Month Nav Returns -9.58698
Trailing Three Month Returns -9.58698
Triggerable 1
Two Hundred Day Average 56.858604
Two Hundred Day Average Change -6.588604
Two Hundred Day Average Change Percent -0.11587699
Type Disp ETF
Volume 18,632
Yield 0.0
Ytd Return 14.15274