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Relay Therapeutics, Inc. (RLAY)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGM
18.77 USD -0.65 (-3.347%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 19.10 +0.33 (1.761%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:32 a.m. EDT

The long-term investment case is effectively zero due to a catastrophic five-year price trajectory where the stock has lost over 90% of its value, driven by five consecutive years of negative annual returns. Despite the company's pristine balance sheet—holding nearly $900 million in cash against negligible debt—the market has priced in a fundamental failure, evidenced by shrinking revenues and negative operating margins. The massive cash pile acts as a temporary life-support system rather than a catalyst for immediate recovery, as the business is currently burning through capital without generating income. Short-term momentum remains fragile; while the stock recently rallied on inclusion in a major index, the options market is aggressively betting against any move higher, with significant put walls placed well above the current trading range. The disconnect between the fortress-like balance sheet and the crushed share price creates a volatile environment where the stock could remain depressed until a specific clinical trial success or partnership deal forces a re-rating, but based on current fundamentals and the relentless multi-year decline, the outlook is severely bearish.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.066147
AutoTheta0.142758
AutoETS0.162686
MSTL0.166523

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 36%
H-stat 0.31
Ljung-Box p 0.000
Jarque-Bera p 0.538
Excess Kurtosis -0.80
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.445
Revenue per Share 0.057
Market Cap 4,113,288,448
Forward P/E -11.42
Beta 1.70
Website https://www.relaytx.com

As of Aug. 22, 2026, 5:32 a.m. EDT: Speculators are positioning defensively with heavy put volume and open interest at strikes significantly above the current price (e.g., $25, $28, $30), creating a 'glass ceiling' effect. While there is some call flow at near-the-money strikes ($20), the overwhelming open interest concentration in deep out-of-the-money puts suggests a market expectation of further downside or a lack of belief in a sustained rally above current levels.


Info Dump

Attribute Value
52 Week Change 4.3060107
Address1 60 Hampshire Street
All Time High 64.37
All Time Low 1.775
Ask 24.83
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 2,416,370
Average Daily Volume3 Month 3,325,120
Average Volume 3,325,120
Average Volume10Days 2,416,370
Beta 1.704
Bid 14.35
Bid Size 2
Board Risk 6
Book Value 4.073
City Cambridge
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 18.77
Current Ratio 18.268
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 19.3
Day Low 18.63
Debt To Equity 3.445
Display Name Relay Therapeutics
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -308,224,000
Ebitda Margins 0.0
Enterprise To Ebitda -10.489
Enterprise To Revenue 312.368
Enterprise Value 3,233,012,480
Eps Current Year -1.6291
Eps Forward -1.64292
Eps Trailing Twelve Months -1.56
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 19.1521
Fifty Day Average Change -0.38209915
Fifty Day Average Change Percent -0.019950772
Fifty Two Week Change Percent 430.60107
Fifty Two Week High 21.27
Fifty Two Week High Change -2.5
Fifty Two Week High Change Percent -0.11753643
Fifty Two Week Low 3.57
Fifty Two Week Low Change 15.200001
Fifty Two Week Low Change Percent 4.2577033
Fifty Two Week Range 3.57 - 21.27
Financial Currency USD
First Trade Date Milliseconds 1,594,906,200,000
Float Shares 145,404,855
Forward Eps -1.64292
Forward P E -11.424781
Free Cashflow -119,241,872
Full Exchange Name NasdaqGM
Full Time Employees 202
Fullday Change -0.65
Fullday Change Percent -3.34706
Fullday Price 19.1006
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Gross Profits -258,496,000
Has Pre Post Market Data 1
Held Percent Insiders 0.01642
Held Percent Institutions 1.1355001
Implied Shares Outstanding 219,141,631
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-07-16
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company. It transforms the drug discovery process with a focus on enhancing small molecule therapeutic discovery in targeted oncology and genetic disease indications. The company's lead product candidates include RLY-2608, a pan-mutant and isoform-selective phosphoinostide 3 kinase alpha, or PI3Ka, inhibitor that is in clinical development for the treatment of breast cancer, solid tumor, and vascular malformations; and aGal chaperone for Fabry diseases. It also develops RLY-8161, an oncogene driver that belongs to the RAS family of signaling proteins. In addition, the company develops lirafugratinib (RLY-4008), a receptor tyrosine kinase for the treatment of cancer. It has collaboration and license agreements with D. E. Shaw Research, LLC to research certain biological targets through the use of D. E. Shaw Research computational modeling capabilities focused on analysis of protein motion to develop and commercialize compounds and products directed to such targets; Elevar Therapeutics, Inc. for the development and commercialization of RLY-4008; and Pfizer Inc. for the development of RLY-2608 in combination with fulvestrant and atirmociclib. The company was formerly known as Allostery, Inc. and changed its name to Relay Therapeutics, Inc. in December 2015. Relay Therapeutics, Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Long Name Relay Therapeutics, Inc.
Market us_market
Market Cap 4,113,288,448
Market State CLOSED
Max Age 86,400
Message Board Id finmb_384027698
Most Recent Quarter 1,782,777,600
Net Income To Common -286,036,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 4,255,730,474
Number Of Analyst Opinions 13
Open 19.15
Operating Cashflow -212,204,992
Operating Margins -259.49716
Overall Risk 8
Payout Ratio 0.0
Phone 617 370 8837
Post Market Change 0.33059883
Post Market Change Percent 1.761315
Post Market Price 19.1006
Post Market Time 1,787,959,806
Previous Close 19.42
Price Eps Current Year -11.5217
Price Hint 2
Price To Book 4.608397
Price To Sales Trailing12 Months 397.41916
Profit Margins 0.0
Quick Ratio 17.93
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.21429
Region US
Regular Market Change -0.65
Regular Market Change Percent -3.34706
Regular Market Day High 19.3
Regular Market Day Low 18.63
Regular Market Day Range 18.63 - 19.3
Regular Market Open 19.15
Regular Market Previous Close 19.42
Regular Market Price 18.77
Regular Market Time 1,787,947,200
Regular Market Volume 2,762,698
Return On Assets -0.22875999
Return On Equity -0.36773998
Revenue Growth -0.483
Revenue Per Share 0.057
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 219,141,631
Shares Percent Shares Out 0.1887
Shares Short 41,359,202
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 42,557,689
Short Name Relay Therapeutics, Inc.
Short Percent Of Float 0.2198
Short Ratio 19.54
Source Interval 15
State MA
Symbol RLAY
Target High Price 32.0
Target Low Price 20.0
Target Mean Price 27.07692
Target Median Price 26.0
Total Cash 910,934,016
Total Cash Per Share 4.157
Total Debt 30,658,000
Total Revenue 10,350,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.56
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 12.592025
Two Hundred Day Average Change 6.1779757
Two Hundred Day Average Change Percent 0.49062607
Type Disp Equity
Volume 2,762,698
Website https://www.relaytx.com
Zip 2,139