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Relay Therapeutics, Inc. (RLAY)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGM
16.28 USD -1.02 (-5.896%) ⇩ (Oct. 16, 2026, 4 p.m. EDT)
After hours: 16.27 -0.01 (-0.010%) ⇩ (Oct. 16, 2026, 4:19 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 7:48 a.m. EDT

The long-term investment case is effectively broken. The company has endured five consecutive years of negative annual returns, culminating in an 84.58% cumulative decline over the last half-decade. This is not a temporary setback; it is a structural deterioration where the market has repeatedly rejected the business thesis. Fundamentals confirm the distress: revenue has contracted by nearly 50%, operating margins are deeply negative, and the company is burning cash with no path to profitability visible in the forward estimates. While the balance sheet currently holds due to a recent capital raise, the underlying asset quality has eroded significantly. In the short term, the stock is trapped in a tug-of-war between a recent 74% rally and the weight of its history. The recent price action shows a pullback from highs, trading below its 50-day average, which suggests the initial euphoria is fading. Options activity reveals a disconnect: traders are buying cheap insurance against a crash (deep puts) while placing long-term lottery tickets on a miracle recovery (far-dated calls). This creates a volatile, choppy environment unsuitable for a standard entry. The statistical forecast offers no guidance, confirming the noise-heavy nature of the price action. Until the company demonstrates sustained revenue growth and a return to profitability, the risk of permanent capital loss outweighs any potential for a rebound.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.064192
AutoETS0.069999
AutoTheta0.112332
AutoARIMA0.193520

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 35%
H-stat 6.22
Ljung-Box p 0.000
Jarque-Bera p 0.941
Excess Kurtosis -0.22
Attribute Value
Sector Healthcare
Debt to Equity Ratio 3.445
Revenue per Share 0.057
Market Cap 3,567,625,984
Forward P/E -9.97
Beta 1.73
Website https://www.relaytx.com

As of Oct. 10, 2026, 7:48 a.m. EDT: Speculators are positioning for significant volatility rather than a clear directional move. There is heavy put volume at deep strikes (below $10) and moderate out-of-the-money put walls, indicating a fear of further downside or a 'crash' scenario. Conversely, there is massive open interest in far-dated calls ($30 strike in 2028), suggesting a speculative bet on a massive recovery or biotech breakthrough, while near-term call activity is thin and dominated by out-of-the-money strikes. The implied volatility skew shows elevated premiums for deep puts, reflecting a high-risk sentiment profile.


Info Dump

Attribute Value
52 Week Change 1.6656394
Address1 60 Hampshire Street
All Time High 64.37
All Time Low 1.775
Ask 24.83
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 2,796,770
Average Daily Volume3 Month 2,770,987
Average Volume 2,770,987
Average Volume10Days 2,796,770
Beta 1.731
Bid 14.35
Bid Size 2
Board Risk 6
Book Value 4.073
City Cambridge
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 16.28
Current Ratio 18.268
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 17.17
Day Low 16.13
Debt To Equity 3.445
Display Name Relay Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,786,046,400
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -308,224,000
Ebitda Margins 0.0
Enterprise To Ebitda -9.444
Enterprise To Revenue 281.244
Enterprise Value 2,910,874,112
Eps Current Year -1.61364
Eps Forward -1.63227
Eps Trailing Twelve Months -1.56
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 18.914
Fifty Day Average Change -2.6339989
Fifty Day Average Change Percent -0.13926187
Fifty Two Week Change Percent 166.56393
Fifty Two Week High 21.27
Fifty Two Week High Change -4.99
Fifty Two Week High Change Percent -0.2346027
Fifty Two Week Low 5.95
Fifty Two Week Low Change 10.330001
Fifty Two Week Low Change Percent 1.7361346
Fifty Two Week Range 5.95 - 21.27
Financial Currency USD
First Trade Date Milliseconds 1,594,906,200,000
Float Shares 145,549,488
Forward Eps -1.63227
Forward P E -9.973841
Free Cashflow -119,241,872
Full Exchange Name NasdaqGM
Full Time Employees 202
Fullday Change -1.0299988
Fullday Change Percent -5.9537506
Fullday Price 16.27
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Gross Profits -258,496,000
Has Pre Post Market Data 1
Held Percent Insiders 0.015759999
Held Percent Institutions 1.10878
Implied Shares Outstanding 219,141,631
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-07-16
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company. It transforms the drug discovery process with a focus on enhancing small molecule therapeutic discovery in targeted oncology and genetic disease indications. The company's lead product candidates include RLY-2608, a pan-mutant and isoform-selective phosphoinostide 3 kinase alpha, or PI3Ka, inhibitor that is in clinical development for the treatment of breast cancer, solid tumor, and vascular malformations; and aGal chaperone for Fabry diseases. It also develops RLY-8161, an oncogene driver that belongs to the RAS family of signaling proteins. In addition, the company develops lirafugratinib (RLY-4008), a receptor tyrosine kinase for the treatment of cancer. It has collaboration and license agreements with D. E. Shaw Research, LLC to research certain biological targets through the use of D. E. Shaw Research computational modeling capabilities focused on analysis of protein motion to develop and commercialize compounds and products directed to such targets; Elevar Therapeutics, Inc. for the development and commercialization of RLY-4008; and Pfizer Inc. for the development of RLY-2608 in combination with fulvestrant and atirmociclib. The company was formerly known as Allostery, Inc. and changed its name to Relay Therapeutics, Inc. in December 2015. Relay Therapeutics, Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Long Name Relay Therapeutics, Inc.
Market us_market
Market Cap 3,567,625,984
Market State POST
Max Age 86,400
Message Board Id finmb_384027698
Most Recent Quarter 1,782,777,600
Net Income To Common -286,036,992
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 3,951,123,606
Number Of Analyst Opinions 12
Open 17.17
Operating Cashflow -212,204,992
Operating Margins -259.49716
Overall Risk 8
Payout Ratio 0.0
Phone 617 370 8837
Post Market Change -0.010000229
Post Market Change Percent -0.061426464
Post Market Price 16.27
Post Market Time 1,792,181,947
Previous Close 17.3
Price Eps Current Year -10.088992
Price Hint 2
Price To Book 3.997054
Price To Sales Trailing12 Months 344.69815
Profit Margins 0.0
Quick Ratio 17.93
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.23077
Region US
Regular Market Change -1.0199986
Regular Market Change Percent -5.895946
Regular Market Day High 17.17
Regular Market Day Low 16.13
Regular Market Day Range 16.13 - 17.17
Regular Market Open 17.17
Regular Market Previous Close 17.3
Regular Market Price 16.28
Regular Market Time 1,792,180,800
Regular Market Volume 2,366,617
Return On Assets -0.22875999
Return On Equity -0.36773998
Revenue Growth -0.483
Revenue Per Share 0.057
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 219,141,631
Shares Percent Shares Out 0.2133
Shares Short 46,746,942
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 43,550,416
Short Name Relay Therapeutics, Inc.
Short Percent Of Float 0.2484
Short Ratio 13.32
Source Interval 15
State MA
Symbol RLAY
Target High Price 32.0
Target Low Price 20.0
Target Mean Price 27.58333
Target Median Price 27.5
Total Cash 910,934,016
Total Cash Per Share 4.157
Total Debt 30,658,000
Total Revenue 10,350,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.56
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 14.435925
Two Hundred Day Average Change 1.8440762
Two Hundred Day Average Change Percent 0.12774216
Type Disp Equity
Volume 2,366,617
Website https://www.relaytx.com
Zip 2,139