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Repligen Corporation (RGEN)

Healthcare | Medical Instruments & Supplies | Waltham, United States | NasdaqGS
176.27 USD -5.76 (-3.164%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 181.00 +4.73 (2.683%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★★★☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:04 a.m. EDT

Repligen is showing aggressive price strength, rallying nearly twenty percent in just two weeks to trade well above its moving averages. This momentum is compelling for a short-term swing, yet the underlying business is in a painful transition. While revenue is growing at a healthy eleven percent, earnings have collapsed by sixty-six percent, leaving the stock priced on a forward multiple that still feels stretched. The market is clearly betting on a turnaround, evidenced by the heavy call open interest at current levels, but the options flow reveals significant hedging activity that could dampen further upside if the earnings story doesn't stabilize quickly. The recent acquisition of BioLife adds strategic weight to the cell therapy segment, but the balance sheet carries debt that requires careful monitoring. For now, the technicals are screaming buy, but the fundamentals are screaming caution until the earnings trough bottoms out.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.134705
AutoETS0.134705
AutoTheta0.134752
MSTL0.135639

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 38%
H-stat 4.91
Ljung-Box p 0.000
Jarque-Bera p 0.797
Excess Kurtosis -0.23
Attribute Value
Sector Healthcare
Debt to Equity Ratio 32.715
Revenue per Share 13.936
Market Cap 9,947,907,072
Trailing P/E 251.81
Forward P/E 66.79
Beta 1.01
Profit Margins 5.29%
Website https://www.repligen.com

As of Aug. 22, 2026, 4:04 a.m. EDT: Speculators are positioning defensively with heavy put volume at the 120 and 135 strikes for near-term expirations, suggesting a fear of a pullback despite the recent rally. Implied volatility is spiking significantly on November 2026 puts compared to calls. However, call open interest remains concentrated at the 165 and 180 strikes, indicating institutional support at current levels. The mix suggests a 'buy the dip' strategy rather than a breakout confirmation.


Info Dump

Attribute Value
52 Week Change 0.5082443
Address1 Building 1
Address2 Suite 100 41 Seyon Street
All Time High 327.32
All Time Low 0.5
Ask 178.06
Ask Size 1
Audit Risk 10
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 1,009,830
Average Daily Volume3 Month 1,109,877
Average Volume 1,109,877
Average Volume10Days 1,009,830
Beta 1.012
Bid 176.08
Bid Size 1
Board Risk 4
Book Value 37.429
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 4
Country United States
Crypto Tradeable 0
Currency USD
Current Price 176.27
Current Ratio 9.05
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 181.345
Day Low 175.695
Debt To Equity 32.715
Display Name Repligen
Earnings Call Timestamp End 1,785,240,000
Earnings Call Timestamp Start 1,785,240,000
Earnings Growth -0.659
Earnings Quarterly Growth -0.663
Earnings Timestamp 1,785,241,800
Earnings Timestamp End 1,793,709,000
Earnings Timestamp Start 1,793,709,000
Ebitda 144,100,992
Ebitda Margins 0.18354
Enterprise To Ebitda 68.205
Enterprise To Revenue 12.519
Enterprise Value 9,828,400,128
Eps Current Year 2.06415
Eps Forward 2.63905
Eps Trailing Twelve Months 0.7
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 781 250 0115
Fifty Day Average 150.9288
Fifty Day Average Change 25.341202
Fifty Day Average Change Percent 0.1679017
Fifty Two Week Change Percent 50.82443
Fifty Two Week High 188.73
Fifty Two Week High Change -12.459991
Fifty Two Week High Change Percent -0.0660202
Fifty Two Week Low 100.99
Fifty Two Week Low Change 75.28001
Fifty Two Week Low Change Percent 0.7454204
Fifty Two Week Range 100.99 - 188.73
Financial Currency USD
First Trade Date Milliseconds 515,165,400,000
Float Shares 53,473,880
Forward Eps 2.63905
Forward P E 66.79298
Free Cashflow 113,421,752
Full Exchange Name NasdaqGS
Full Time Employees 2,000
Fullday Change -5.75999
Fullday Change Percent -3.16431
Fullday Price 181.0
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.53836
Gross Profits 422,667,008
Has Pre Post Market Data 1
Held Percent Insiders 0.05242
Held Percent Institutions 1.20076
Implied Shares Outstanding 56,435,621
Industry Medical Instruments & Supplies
Industry Disp Medical Instruments & Supplies
Industry Key medical-instruments-supplies
Ir Website http://www.repligen.com/investor-relations/shareholder-center
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Repligen Corporation, a life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally. The company's products include hollow fiber consumables, KRM chromatography system, resins for new modalities, PATsmart MAVERICK and PATsmart MAVEN for real-time monitoring and control of critical bioprocess parameters, PATsmart REBEL, an at-line cell culture media analyzer; and PATsmart ZipChip, a high-resolution sample separations device, PATsmart SoloVPE slope spectroscopy system, and SoloVPE PLUS System. It offers Protien A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company also provides chromatography products, including OPUS pre-packed chromatography columns, which are used in the purification and quality control of biological drugs, as well as ELISA test kits. In addition, it offers filtration products, such as XCell ATF Cell Retention Systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration, buffer exchange, and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; and ProConnex TFDF flow paths. Further, it provides process analytics products, such as slope spectroscopy systems. The company offers its products under the OPUS, XCell, XCell ATF, TFDF, KrosFlo, SIUS, ProConnex, Spectra/Por, NGL-Impact, SoloVPE, FlowVPE, RPM, XO, Metenova MixOne, and AVIPure and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has a collaboration agreement with Navigo Proteins GmbH to develop multiple affinity ligands. The company was incorporated in 1981 and is headquartered in Waltham, Massachusetts.
Long Name Repligen Corporation
Market us_market
Market Cap 9,947,907,072
Market State CLOSED
Max Age 86,400
Message Board Id finmb_33769
Most Recent Quarter 1,782,777,600
Net Income To Common 41,539,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 10,272,976,090
Number Of Analyst Opinions 20
Open 179.76
Operating Cashflow 134,864,000
Operating Margins 0.09309
Overall Risk 4
Payout Ratio 0.0
Peg Ratio 2.42
Phone 781 250 0111
Post Market Change 4.7299957
Post Market Change Percent 2.6833808
Post Market Price 181.0
Post Market Time 1,787,959,805
Previous Close 182.03
Price Eps Current Year 85.39593
Price Hint 2
Price To Book 4.70945
Price To Sales Trailing12 Months 12.670863
Profit Margins 0.05291
Quick Ratio 7.298
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.5
Region US
Regular Market Change -5.75999
Regular Market Change Percent -3.16431
Regular Market Day High 181.345
Regular Market Day Low 175.695
Regular Market Day Range 175.695 - 181.345
Regular Market Open 179.76
Regular Market Previous Close 182.03
Regular Market Price 176.27
Regular Market Time 1,787,947,200
Regular Market Volume 818,464
Return On Assets 0.01395
Return On Equity 0.0199
Revenue Growth 0.119
Revenue Per Share 13.936
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 1
Shares Outstanding 56,435,621
Shares Percent Shares Out 0.1078
Shares Short 6,085,313
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 5,811,745
Short Name Repligen Corporation
Short Percent Of Float 0.1082
Short Ratio 4.86
Source Interval 15
State MA
Symbol RGEN
Target High Price 220.0
Target Low Price 145.0
Target Mean Price 185.7
Target Median Price 185.0
Total Cash 810,449,024
Total Cash Per Share 14.361
Total Debt 690,942,016
Total Revenue 785,100,992
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.7
Trailing P E 251.8143
Trailing Peg Ratio 2.4261
Triggerable 1
Two Hundred Day Average 141.3328
Two Hundred Day Average Change 34.93721
Two Hundred Day Average Change Percent 0.24719818
Type Disp Equity
Volume 818,464
Website https://www.repligen.com
Zip 2,453