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Repligen Corporation (RGEN)

Healthcare | Medical Instruments & Supplies | Waltham, United States | NasdaqGS
131.21 USD +4.12 (3.242%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 132.00 +0.79 (0.602%) ⇧ (April 17, 2026, 6:17 p.m. EDT)

Short-term: ★☆☆☆☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 1:51 a.m. EDT

Repligen is trapped between a short squeeze demand (28% short rise, bad option position) and a devastating disconnect between 2024 highs ($175) and current valuation. While the fundamental story includes robust cash reserves and growth in positivity, the recent earnings 'disappointing' 2026 guidance triggered a sell-off to ~$110, creating a classic technical oversold zone. Short-term momentum is mixed, but the option data shows 'smart money' placing heavy protective bags at $110ish, suggesting the recent drop has found a support floor. Watch for the guidance re-rating in the next 45 days as the primary catalyst to unlock the 165-170 resistance zone.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.248090
AutoARIMA0.248090
MSTL0.257641
AutoTheta0.283234

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 49%
H-stat 4.61
Ljung-Box p 0.000
Jarque-Bera p 0.178
Excess Kurtosis -0.60
Attribute Value
Sector Healthcare
Debt to Equity Ratio 32.759
Revenue per Share 13.128
Market Cap 7,400,148,992
Trailing P/E 150.82
Forward P/E 52.12
Beta 1.19
Profit Margins 6.62%
Website https://www.repligen.com

As of April 19, 2026, 1:51 a.m. EDT: Options data reveals a significant 'bad position' (high OI near 130-135 ATM) surrounding the April 17 and May 15 expirations, typical of a hedging ban or 'short square' area intended to force price movement through or stagnate around current levels. A massive 500-volume call spike at the 110 strike for May 15 suggests a strong floor perception. However, for June 18 and beyond, OI heavily accumulates at the 150-170 strike range, capping upside expectations significantly. Implied Volatility (IV) is elevated (approx. 95-160%) for immediately realistic moves but compresses sharply to 50-60% for the 165+ ATM strikes later in the year, indicating traders are not pricing in a multi-year resumption to pre-2023 highs.


Info Dump

Attribute Value
52 Week Change -0.0032665133
Address1 Building 1
Address2 Suite 100 41 Seyon Street
All Time High 327.32
All Time Low 0.5
Ask 131.43
Ask Size 3
Audit Risk 10
Average Analyst Rating 1.5 - Buy
Average Daily Volume10 Day 783,100
Average Daily Volume3 Month 849,667
Average Volume 849,667
Average Volume10Days 783,100
Beta 1.189
Bid 130.88
Bid Size 3
Board Risk 2
Book Value 37.392
City Waltham
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 5
Country United States
Crypto Tradeable 0
Currency USD
Current Price 131.21
Current Ratio 8.374
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 134.23
Day Low 130.285
Debt To Equity 32.759
Display Name Repligen
Earnings Call Timestamp End 1,771,939,800
Earnings Call Timestamp Start 1,771,939,800
Earnings Timestamp 1,771,939,800
Earnings Timestamp End 1,777,379,400
Earnings Timestamp Start 1,777,379,400
Ebitda 124,440,000
Ebitda Margins 0.16856001
Enterprise To Ebitda 58.771
Enterprise To Revenue 9.906
Enterprise Value 7,313,524,736
Eps Current Year 1.9683
Eps Forward 2.51734
Eps Trailing Twelve Months 0.87
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 781 250 0115
Fifty Day Average 125.1968
Fifty Day Average Change 6.0132065
Fifty Day Average Change Percent 0.048030034
Fifty Two Week Change Percent -0.32665133
Fifty Two Week High 175.77
Fifty Two Week High Change -44.559998
Fifty Two Week High Change Percent -0.2535131
Fifty Two Week Low 109.66
Fifty Two Week Low Change 21.550003
Fifty Two Week Low Change Percent 0.19651653
Fifty Two Week Range 109.66 - 175.77
Financial Currency USD
First Trade Date Milliseconds 515,165,400,000
Float Shares 53,295,990
Forward Eps 2.51734
Forward P E 52.122482
Free Cashflow 76,066,248
Full Exchange Name NasdaqGS
Full Time Employees 2,000
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.52653
Gross Profits 388,712,000
Has Pre Post Market Data 1
Held Percent Insiders 0.05292
Held Percent Institutions 1.12702
Implied Shares Outstanding 56,399,274
Industry Medical Instruments & Supplies
Industry Disp Medical Instruments & Supplies
Industry Key medical-instruments-supplies
Ir Website http://www.repligen.com/investor-relations/shareholder-center
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Repligen Corporation, a life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally. The company's products include hollow fiber consumables, KRM chromatography system, resins for new modalities, PATsmart MAVERICK and PATsmart MAVEN for real-time monitoring and control of critical bioprocess parameters, PATsmart REBEL, an at-line cell culture media analyzer; and PATsmart ZipChip, a high-resolution sample separations device, PATsmart SoloVPE slope spectroscopy system, and SoloVPE PLUS System. It offers Protien A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company also provides chromatography products, including OPUS pre-packed chromatography columns, which are used in the purification and quality control of biological drugs, as well as ELISA test kits. In addition, it offers filtration products, such as XCell ATF Cell Retention Systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration, buffer exchange, and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; and ProConnex TFDF flow paths. Further, it provides process analytics products, such as slope spectroscopy systems. The company offers its products under the OPUS, XCell, XCell ATF, TFDF, KrosFlo, SIUS, ProConnex, Spectra/Por, NGL-Impact, SoloVPE, FlowVPE, RPM, XO, Metenova MixOne, and AVIPure and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has a collaboration agreement with Navigo Proteins GmbH to develop multiple affinity ligands. The company was incorporated in 1981 and is headquartered in Waltham, Massachusetts.
Long Name Repligen Corporation
Market us_market
Market Cap 7,400,148,992
Market State CLOSED
Max Age 86,400
Message Board Id finmb_33769
Most Recent Quarter 1,767,139,200
Net Income To Common 48,894,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 7,401,840,719
Number Of Analyst Opinions 18
Open 131.31
Operating Cashflow 117,417,000
Operating Margins 0.082600005
Overall Risk 4
Payout Ratio 0.0
Peg Ratio 8.23
Phone 781 250 0111
Post Market Change 0.7899933
Post Market Change Percent 0.6020831
Post Market Price 132.0
Post Market Time 1,776,464,244
Previous Close 127.09
Price Eps Current Year 66.66159
Price Hint 2
Price To Book 3.5090396
Price To Sales Trailing12 Months 10.023825
Profit Margins 0.06623
Quick Ratio 6.819
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.52381
Region US
Regular Market Change 4.12001
Regular Market Change Percent 3.24181
Regular Market Day High 134.23
Regular Market Day Low 130.285
Regular Market Day Range 130.285 - 134.23
Regular Market Open 131.31
Regular Market Previous Close 127.09
Regular Market Price 131.21
Regular Market Time 1,776,456,000
Regular Market Volume 1,122,130
Return On Assets 0.00988
Return On Equity 0.02397
Revenue Growth 0.181
Revenue Per Share 13.128
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 1
Shares Outstanding 56,399,274
Shares Percent Shares Out 0.098500006
Shares Short 5,556,333
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 4,003,984
Short Name Repligen Corporation
Short Percent Of Float 0.0988
Short Ratio 6.38
Source Interval 15
State MA
Symbol RGEN
Target High Price 220.0
Target Low Price 140.0
Target Mean Price 180.88889
Target Median Price 180.0
Total Cash 767,628,032
Total Cash Per Share 13.627
Total Debt 689,948,032
Total Revenue 738,256,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.87
Trailing P E 150.8161
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 138.32526
Two Hundred Day Average Change -7.1152496
Two Hundred Day Average Change Percent -0.051438544
Type Disp Equity
Volume 1,122,130
Website https://www.repligen.com
Zip 2,453