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Replimune Group, Inc. (REPL)

Healthcare | Biotechnology | Woburn, United States | NasdaqGS
9.94 USD -1.06 (-9.600%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 9.80 -0.14 (-0.135%) ⇩ (July 13, 2026, 7:41 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:38 a.m. EDT

The investment case for Replimune is currently paralyzed by the binary nature of its FDA decision on its melanoma drug. Fundamentally, the company is in distress: it is burning significant cash with negative free cash flow and negative returns on equity, and the stock has suffered a severe multi-year decline, dropping nearly 53% in the last year alone. This trajectory suggests the market has already priced in a failure of the drug or a lack of commercial viability, leaving the balance sheet fragile. While the recent price action shows some resilience and a slight uptick in the trailing twelve months, the underlying business metrics remain deeply concerning with no path to profitability visible. The options market confirms this tension, with heavy betting on both a catastrophic drop and a miraculous approval, but the lack of a reliable catalyst beyond the FDA vote makes the risk-reward profile unattractive for a standard investor. Without a confirmed approval and a clear plan to generate revenue, the stock remains a speculative gamble on a binary event rather than a sound investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.886439
AutoETS0.928547
AutoARIMA0.930122
AutoTheta0.949323

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 25%
H-stat 10.66
Ljung-Box p 0.000
Jarque-Bera p 0.156
Excess Kurtosis -1.05
Attribute Value
Sector Healthcare
Debt to Equity Ratio 67.156
Market Cap 833,995,200
Forward P/E -8.61
Beta 0.87
Website https://www.replimune.com

As of July 11, 2026, 4:38 a.m. EDT: Speculators are positioning aggressively for volatility rather than a specific directional outcome. There is a massive concentration of out-of-the-money put open interest at strikes significantly below the current price (e.g., $2, $5, $6), indicating a 'crash' hedge or a bet on regulatory rejection driving the stock lower. Conversely, there is also heavy call open interest at distant strikes ($17, $20), suggesting a binary bet on a successful FDA approval causing a sharp spike. The implied volatility is elevated across the board, reflecting uncertainty surrounding the upcoming FDA decision. The options flow suggests a polarized view where traders are hedging against a downside event while simultaneously buying deep out-of-the-money calls to capture a potential upside surprise.


Info Dump

Attribute Value
52 Week Change -0.025709212
Address1 500 Unicorn Park Drive
Address2 Suite 303, 3rd Floor
All Time High 54.85
All Time Low 1.5
Ask 12.58
Ask Size 2
Audit Risk 10
Average Analyst Rating 2.9 - Hold
Average Daily Volume10 Day 3,591,940
Average Daily Volume3 Month 6,668,924
Average Volume 6,668,924
Average Volume10Days 3,591,940
Beta 0.868
Bid 7.78
Bid Size 2
Board Risk 8
Book Value 2.009
City Woburn
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 9.935
Current Ratio 4.794
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 10.91
Day Low 9.79
Debt To Equity 67.156
Display Name Replimune
Earnings Call Timestamp End 1,747,915,200
Earnings Call Timestamp Start 1,747,915,200
Earnings Timestamp 1,782,736,200
Earnings Timestamp End 1,786,019,400
Earnings Timestamp Start 1,786,019,400
Ebitda -312,555,008
Ebitda Margins 0.0
Enterprise To Ebitda -2.165
Enterprise Value 676,692,160
Eps Current Year -1.935
Eps Forward -1.15333
Eps Trailing Twelve Months -3.38
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 7.647
Fifty Day Average Change 2.2880006
Fifty Day Average Change Percent 0.29920238
Fifty Two Week Change Percent -2.5709212
Fifty Two Week High 13.24
Fifty Two Week High Change -3.3049994
Fifty Two Week High Change Percent -0.24962232
Fifty Two Week Low 1.5
Fifty Two Week Low Change 8.435
Fifty Two Week Low Change Percent 5.6233335
Fifty Two Week Range 1.5 - 13.24
Financial Currency USD
First Trade Date Milliseconds 1,532,093,400,000
Float Shares 59,711,872
Forward Eps -1.15333
Forward P E -8.614187
Free Cashflow -172,249,744
Full Exchange Name NasdaqGS
Full Time Employees 465
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.0256
Held Percent Institutions 0.95449996
Implied Shares Outstanding 83,945,161
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,774,915,200
Long Business Summary Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of oncolytic immunotherapies to treat cancer in the United States and the United Kingdom. The company's proprietary oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF for a range of solid tumors. The company is also developing RP2 that expresses an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4. The company was founded in 2015 and is headquartered in Woburn, Massachusetts.
Long Name Replimune Group, Inc.
Market us_market
Market Cap 833,995,200
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_571664452
Most Recent Quarter 1,774,915,200
Net Income To Common -313,940,000
Next Fiscal Year End 1,806,451,200
Non Diluted Market Cap 922,977,045
Number Of Analyst Opinions 6
Open 10.9
Operating Cashflow -280,344,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 781 222 9600
Post Market Change -0.13500023
Post Market Change Percent -1.3588346
Post Market Price 9.8
Post Market Time 1,783,986,076
Previous Close 10.99
Price Eps Current Year -5.1343675
Price Hint 2
Price To Book 4.945246
Profit Margins 0.0
Quick Ratio 4.646
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key hold
Recommendation Mean 2.875
Region US
Regular Market Change -1.055
Regular Market Change Percent -9.59963
Regular Market Day High 10.91
Regular Market Day Low 9.79
Regular Market Day Range 9.79 - 10.91
Regular Market Open 10.9
Regular Market Previous Close 10.99
Regular Market Price 9.935
Regular Market Time 1,783,972,800
Regular Market Volume 2,828,130
Return On Assets -0.45025003
Return On Equity -1.07883
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 83,945,161
Shares Percent Shares Out 0.28190002
Shares Short 23,666,879
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 25,954,343
Short Name Replimune Group, Inc.
Short Percent Of Float 0.4988
Short Ratio 5.48
Source Interval 15
State MA
Symbol REPL
Target High Price 17.0
Target Low Price 2.0
Target Mean Price 10.66667
Target Median Price 10.0
Total Cash 268,888,992
Total Cash Per Share 3.203
Total Debt 111,586,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.38
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 7.4691
Two Hundred Day Average Change 2.4659004
Two Hundred Day Average Change Percent 0.33014694
Type Disp Equity
Volume 2,828,130
Website https://www.replimune.com
Zip 1,801