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Replimune Group, Inc. (REPL)

Healthcare | Biotechnology | Woburn, United States | NasdaqGS
15.50 USD -0.10 (-0.641%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 15.45 -0.05 (-0.050%) ⇩ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 5:17 a.m. EDT

The investment case for Replimune is currently defined by a binary event risk rather than sustainable business fundamentals. The company is burning cash with negative free cash flow and a deteriorating balance sheet, while the stock has suffered a catastrophic 66% decline over the past seven years, reflecting the market's severe skepticism about its ability to execute. Although the FDA review acceptance offers a potential catalyst, the odds are stacked against the stock; the massive accumulation of put options by speculators suggests a consensus view that the upcoming decision could trigger further downside, not a rally. With no dividend to provide income and a history of multi-year declines, this is a speculative gamble on a clinical trial outcome rather than a sound investment vehicle. The short interest nearing 44% indicates heavy skepticism among retail investors, who may eventually force a squeeze, but the fundamental reality remains a distressed biotech play with no margin of safety.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.262108
AutoTheta0.263312
AutoETS0.263366
MSTL0.312027

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 18%
H-stat 4.08
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 2.91
Attribute Value
Sector Healthcare
Debt to Equity Ratio 105.992
Market Cap 1,460,404,352
Forward P/E -7.61
Beta 0.90
Website https://www.replimune.com

As of Aug. 22, 2026, 5:17 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in deep out-of-the-money puts (strikes 2.0, 3.0, 8.0) across multiple expirations, including significant volume spikes. Conversely, call activity is concentrated near the money or slightly out-of-the-money, with notable open interest walls at strikes significantly below the current price (e.g., 10.0, 13.0), suggesting a 'bear put ladder' strategy rather than a bullish breakout expectation. Implied volatility remains elevated on the downside strikes relative to the at-the-money level.


Info Dump

Attribute Value
52 Week Change 1.6271186
Address1 500 Unicorn Park Drive
Address2 Suite 303, 3rd Floor
All Time High 54.85
All Time Low 1.5
Ask 19.84
Ask Size 2
Audit Risk 10
Average Analyst Rating 1.8 - Buy
Average Daily Volume10 Day 2,833,360
Average Daily Volume3 Month 4,979,992
Average Volume 4,979,992
Average Volume10Days 2,833,360
Beta 0.9
Bid 15.44
Bid Size 3
Board Risk 8
Book Value 1.258
City Woburn
Compensation As Of Epoch Date 1,798,675,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 15.5
Current Ratio 5.228
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 15.87
Day Low 15.4
Debt To Equity 105.992
Display Name Replimune
Earnings Call Timestamp End 1,747,915,200
Earnings Call Timestamp Start 1,747,915,200
Earnings Timestamp 1,786,710,600
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -290,440,000
Ebitda Margins 0.0
Enterprise To Ebitda -4.741
Enterprise Value 1,377,051,264
Eps Current Year -2.97584
Eps Forward -2.03808
Eps Trailing Twelve Months -3.13
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 11.8075
Fifty Day Average Change 3.6925
Fifty Day Average Change Percent 0.31272498
Fifty Two Week Change Percent 162.71185
Fifty Two Week High 16.15
Fifty Two Week High Change -0.6499996
Fifty Two Week High Change Percent -0.040247656
Fifty Two Week Low 1.5
Fifty Two Week Low Change 14.0
Fifty Two Week Low Change Percent 9.333333
Fifty Two Week Range 1.5 - 16.15
Financial Currency USD
First Trade Date Milliseconds 1,532,093,400,000
Float Shares 67,652,524
Forward Eps -2.03808
Forward P E -7.605197
Free Cashflow -171,672,752
Full Exchange Name NasdaqGS
Full Time Employees 465
Fullday Change -0.1
Fullday Change Percent -0.641028
Fullday Price 15.45
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.016490001
Held Percent Institutions 1.04191
Implied Shares Outstanding 94,219,634
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,774,915,200
Long Business Summary Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of oncolytic immunotherapies to treat cancer in the United States and the United Kingdom. The company's proprietary oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF for a range of solid tumors. The company is also developing RP2 that expresses an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4. The company was founded in 2015 and is headquartered in Woburn, Massachusetts.
Long Name Replimune Group, Inc.
Market us_market
Market Cap 1,460,404,352
Market State CLOSED
Max Age 86,400
Message Board Id finmb_571664452
Most Recent Quarter 1,782,777,600
Net Income To Common -297,012,992
Next Fiscal Year End 1,806,451,200
Non Diluted Market Cap 1,469,826,290
Number Of Analyst Opinions 6
Open 15.402
Operating Cashflow -279,056,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 781 222 9600
Post Market Change -0.05000019
Post Market Change Percent -0.3225819
Post Market Price 15.45
Post Market Time 1,787,959,806
Previous Close 15.6
Price Eps Current Year -5.2086134
Price Hint 2
Price To Book 12.321144
Profit Margins 0.0
Quick Ratio 5.085
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 1.75
Region US
Regular Market Change -0.1
Regular Market Change Percent -0.641028
Regular Market Day High 15.87
Regular Market Day Low 15.4
Regular Market Day Range 15.4 - 15.87
Regular Market Open 15.402
Regular Market Previous Close 15.6
Regular Market Price 15.5
Regular Market Time 1,787,947,200
Regular Market Volume 2,386,210
Return On Assets -0.51296
Return On Equity -1.34286
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 94,219,634
Shares Percent Shares Out 0.26389998
Shares Short 24,866,611
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 23,654,362
Short Name Replimune Group, Inc.
Short Percent Of Float 0.43080002
Short Ratio 3.43
Source Interval 15
State MA
Symbol REPL
Target High Price 24.0
Target Low Price 14.0
Target Mean Price 19.5
Target Median Price 19.5
Total Cash 195,328,000
Total Cash Per Share 2.073
Total Debt 111,975,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.13
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.432625
Two Hundred Day Average Change 7.067375
Two Hundred Day Average Change Percent 0.83809906
Type Disp Equity
Volume 2,386,210
Website https://www.replimune.com
Zip 1,801