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Ultragenyx Pharmaceutical Inc. (RARE)

Healthcare | Biotechnology | Novato, United States | NasdaqGS
33.22 USD -0.60 (-1.774%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:40 a.m. EDT

The investment case here is fraught with contradictions. Fundamentally, the business is deteriorating; revenue has contracted by 2.2%, and the company is burning cash with negative operating margins and a book value that is deeply impaired. The multi-year price trajectory confirms this structural weakness, having lost nearly half its value over the last nine years, with the most recent annual performance showing another sharp decline. While the analyst consensus is surprisingly bullish with a mean target implying significant upside, this appears to be a 'buy the dip' narrative unsupported by the current operational reality. Short-term, the stock is technically oversold relative to its moving averages, which explains the recent bounce, but the heavy options activity in deep puts suggests smart money is still worried about further downside. The statistical forecast offers no directional clarity, merely reflecting the noise of a struggling asset. Without a confirmed turnaround in revenue growth or a path to profitability, the long-term outlook remains bleak. This is a high-risk speculative vehicle where the potential for a binary event-driven recovery exists, but the probability of continued value destruction remains high given the lack of sustainable fundamentals.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.060113
AutoETS0.060329
AutoARIMA0.060371
AutoTheta0.062058

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 35%
H-stat 4.83
Ljung-Box p 0.000
Jarque-Bera p 0.289
Excess Kurtosis -0.17
Attribute Value
Sector Healthcare
Revenue per Share 6.722
Market Cap 3,271,812,096
Forward P/E 21.43
Beta 0.31
Profit Margins -90.90%
Website https://www.ultragenyx.com

As of July 11, 2026, 2:40 a.m. EDT: Speculators are positioning aggressively for downside protection with massive volume in deep out-of-the-money puts (strikes 12.5, 15, 17.5, 22.5) expiring in late summer and fall, indicating a fear of a significant drop. Conversely, there is notable call volume at strikes 37.5 and 50 for later dates, suggesting a speculative bet on a recovery or rally, but the overwhelming put flow suggests the market is pricing in a continued struggle or a 'double bottom' scenario rather than an immediate breakout.


Info Dump

Attribute Value
52 Week Change 0.15703046
Address1 60 Leveroni Court
All Time High 179.647
All Time Low 18.29
Ask 40.98
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 4,425,850
Average Daily Volume3 Month 2,197,145
Average Volume 2,197,145
Average Volume10Days 4,425,850
Beta 0.307
Bid 23.84
Bid Size 2
Board Risk 2
Book Value -2.408
City Novato
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 33.22
Current Ratio 2.022
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 33.3
Day Low 31.81
Display Name Ultragenyx Pharmaceutical
Earnings Call Timestamp End 1,778,014,800
Earnings Call Timestamp Start 1,778,014,800
Earnings Timestamp 1,778,011,200
Earnings Timestamp End 1,785,873,600
Earnings Timestamp Start 1,785,873,600
Ebitda -497,000,000
Ebitda Margins -0.74179
Enterprise To Ebitda -8.161
Enterprise To Revenue 6.054
Enterprise Value 4,055,846,144
Eps Current Year -4.24481
Eps Forward 1.55033
Eps Trailing Twelve Months -6.1
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 26.4982
Fifty Day Average Change 6.7218018
Fifty Day Average Change Percent 0.25367013
Fifty Two Week Change Percent 15.703047
Fifty Two Week High 39.89
Fifty Two Week High Change -6.669998
Fifty Two Week High Change Percent -0.16720979
Fifty Two Week Low 18.29
Fifty Two Week Low Change 14.93
Fifty Two Week Low Change Percent 0.81629306
Fifty Two Week Range 18.29 - 39.89
Financial Currency USD
First Trade Date Milliseconds 1,391,178,600,000
Float Shares 94,509,092
Forward Eps 1.55033
Forward P E 21.427696
Free Cashflow -219,090,000
Full Exchange Name NasdaqGS
Full Time Employees 1,371
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins -0.28059998
Gross Profits -188,000,000
Has Pre Post Market Data 1
Held Percent Insiders 0.03451
Held Percent Institutions 1.0185701
Implied Shares Outstanding 98,489,224
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Ultragenyx Pharmaceutical Inc., a biopharmaceutical company, focuses on the identification, acquisition, development, and commercialization of novel products for the treatment of rare and ultra-rare genetic diseases in North America, Latin America, Europe, the Middle East, Africa, and the Asia-Pacific. Its biologic products include Crysvita (burosumab), an antibody targeting fibroblast growth factor 23 for the treatment of X-linked hypophosphatemia, as well as tumor-induced osteomalacia; Mepsevii, an enzyme replacement therapy for the treatment of children and adults with Mucopolysaccharidosis VII; Dojolvi for the treatment of long-chain fatty acid oxidation disorders; and Evkeeza (evinacumab) for the treatment of homozygous familial hypercholesterolemia. The company's products candidates that are in Phase 3 clinical trials include UX143, a human monoclonal antibody for the treatment of osteogenesis imperfecta; UX111, an AAV9 gene therapy product candidate for the treatment of patients with Sanfilippo syndrome type A, or MPS IIIA, a rare lysosomal storage disease; DTX401, an adeno-associated virus 8 (AAV8) gene therapy clinical candidate for the treatment of patients with glycogen storage disease type Ia; DTX301, an AAV8 gene therapy for the treatment of patients with ornithine transcarbamylase; and GTX-102, an antisense oligonucleotide for the treatment of Angelman syndrome. It also develops UX701, an adeno-associated AAV9 gene therapy which is in Phase 2 clinical trial for the treatment of Wilson liver disease. The company has collaboration and license agreement with Kyowa Kirin Co., Ltd.; Saint Louis University; Baylor Research Institute; REGENXBIO Inc.; GeneTx; Mereo; University of Pennsylvania; Regeneron; and Abeona. Ultragenyx Pharmaceutical Inc. was incorporated in 2010 and is headquartered in Novato, California.
Long Name Ultragenyx Pharmaceutical Inc.
Market us_market
Market Cap 3,271,812,096
Market State PRE
Max Age 86,400
Message Board Id finmb_117471985
Most Recent Quarter 1,774,915,200
Net Income To Common -609,000,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 3,330,905,555
Number Of Analyst Opinions 19
Open 33.065
Operating Cashflow -497,000,000
Operating Margins -1.02206
Overall Risk 6
Payout Ratio 0.0
Phone 415 483 8800
Previous Close 33.82
Price Eps Current Year -7.826028
Price Hint 2
Price To Book -13.795682
Price To Sales Trailing12 Months 4.8833017
Profit Margins -0.90896004
Quick Ratio 1.652
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.47368
Region US
Regular Market Change -0.599998
Regular Market Change Percent -1.77409
Regular Market Day High 33.3
Regular Market Day Low 31.81
Regular Market Day Range 31.81 - 33.3
Regular Market Open 33.065
Regular Market Previous Close 33.82
Regular Market Price 33.22
Regular Market Time 1,783,972,800
Regular Market Volume 1,327,332
Return On Assets -0.25451002
Revenue Growth -0.022
Revenue Per Share 6.722
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 7
Shares Outstanding 98,489,224
Shares Percent Shares Out 0.16469999
Shares Short 16,217,153
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 14,703,432
Short Name Ultragenyx Pharmaceutical Inc.
Short Percent Of Float 0.1703
Short Ratio 5.36
Source Interval 15
State CA
Symbol RARE
Target High Price 96.0
Target Low Price 25.0
Target Mean Price 52.52632
Target Median Price 48.0
Total Cash 413,000,000
Total Cash Per Share 4.206
Total Debt 1,200,000,000
Total Revenue 670,000,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -6.1
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 27.15655
Two Hundred Day Average Change 6.063452
Two Hundred Day Average Change Percent 0.22327769
Type Disp Equity
Volume 1,327,332
Website https://www.ultragenyx.com
Zip 94,949