Rapport Therapeutics, Inc. (RAPP)Healthcare | Biotechnology | Boston, United States | NasdaqGM
48.77 USD
-2.06
(-4.053%) ⇩
(Aug. 28, 2026, 4 p.m.
EDT)
After hours: 48.77 |
Hot Take ↕ | Aug. 22, 2026, 1:44 a.m. EDT
The investment case for Rapport Therapeutics is currently defined by a stark disconnect between optimistic analyst sentiment and deteriorating market reality. While analysts maintain a 'strong buy' rating and raised price targets, the stock has suffered a crushing 30% decline over the last year, dragging the price down from $21 to under $15 before a recent, fragile recovery. Fundamentally, the company is in distress: it reports negative gross margins, negative operating cash flow, and a forward P/E that implies continued losses. There is no dividend to cushion the blow, and the balance sheet shows significant free cash burn. The most critical signal here is the options flow. The market is screaming 'sell' or 'hedge,' with traders accumulating thousands of contracts in deep out-of-the-money puts while leaving the call side virtually empty. This aggressive put buying indicates that investors fear a continuation of the downtrend or a failed clinical trial, despite the hype around Phase 3 progress. The statistical forecast model offers only a weak, low-confidence lean upward, which is insufficient to counter the overwhelming bearish positioning in derivatives. For the short term, the stock is hovering near resistance after a volatile bounce, but the lack of genuine bullish options flow and the heavy put wall suggest any further upside is likely to be capped until the underlying business fundamentals turn positive. For the long term, the combination of negative margins, cash burn, and a multi-year price decline makes this a high-risk speculative play rather than a solid buy. The market appears to be pricing in a value trap where the current price does not reflect the severity of the operational challenges. |
| Model | MAE |
|---|---|
| AutoTheta ✓ | 0.072508 |
| MSTL | 0.082206 |
| AutoARIMA | 0.086405 |
| AutoETS | 0.090890 |
Forecast horizon: 45 days | Selected: AutoTheta
| Forecast Reliability | |
|---|---|
| Score | 31% |
| H-stat | 8.95 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.907 |
| Excess Kurtosis | 0.20 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 2.389 |
| Revenue per Share | 0.445 |
| Market Cap | 2,339,901,184 |
| Forward P/E | -9.33 |
| Beta | 0.97 |
| Website | https://www.rapportrx.com |
As of Aug. 22, 2026, 1:44 a.m. EDT: Speculators are heavily positioning for downside protection, evidenced by massive open interest in out-of-the-money puts (strikes $25-$40) expiring late in 2026 and early 2027, while call activity remains negligible outside of immediate ATM anchors. This distribution suggests a market consensus expecting significant volatility or a drop in share price rather than a rally.
| Attribute | Value |
|---|---|
| 52 Week Change | 2.1050704 |
| Address1 | 99 High Street |
| Address2 | Suite 2100 |
| All Time High | 52.93 |
| All Time Low | 6.43 |
| Ask | 52.54 |
| Ask Size | 2 |
| Audit Risk | 5 |
| Average Analyst Rating | 1.1 - Strong Buy |
| Average Daily Volume10 Day | 262,330 |
| Average Daily Volume3 Month | 354,716 |
| Average Volume | 354,716 |
| Average Volume10Days | 262,330 |
| Beta | 0.971 |
| Bid | 30.56 |
| Bid Size | 2 |
| Board Risk | 6 |
| Book Value | 8.819 |
| City | Boston |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 9 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 48.77 |
| Current Ratio | 15.721 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,786,665,600 |
| Day High | 50.6751 |
| Day Low | 48.37 |
| Debt To Equity | 2.389 |
| Display Name | Rapport Therapeutics |
| Earnings Timestamp | 1,785,933,000 |
| Earnings Timestamp End | 1,793,881,800 |
| Earnings Timestamp Start | 1,793,881,800 |
| Ebitda | -152,556,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -12.546 |
| Enterprise To Revenue | 95.696 |
| Enterprise Value | 1,913,928,960 |
| Eps Current Year | -4.09333 |
| Eps Forward | -5.22889 |
| Eps Trailing Twelve Months | -3.03 |
| Esg Populated | 0 |
| Exchange | NGM |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 43.1285 |
| Fifty Day Average Change | 5.6414986 |
| Fifty Day Average Change Percent | 0.13080673 |
| Fifty Two Week Change Percent | 210.50703 |
| Fifty Two Week High | 52.93 |
| Fifty Two Week High Change | -4.16 |
| Fifty Two Week High Change Percent | -0.078594364 |
| Fifty Two Week Low | 14.11 |
| Fifty Two Week Low Change | 34.66 |
| Fifty Two Week Low Change Percent | 2.456414 |
| Fifty Two Week Range | 14.11 - 52.93 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,717,767,000,000 |
| Float Shares | 32,304,740 |
| Forward Eps | -5.22889 |
| Forward P E | -9.327027 |
| Free Cashflow | -56,016,500 |
| Full Exchange Name | NasdaqGM |
| Full Time Employees | 84 |
| Fullday Change | -2.06 |
| Fullday Change Percent | -4.05273 |
| Fullday Price | 48.77 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,785,542,400 |
| Gross Margins | -1.0939 |
| Gross Profits | -21,878,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.0392 |
| Held Percent Institutions | 1.0871 |
| Implied Shares Outstanding | 47,978,286 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,024-06-07 |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts. |
| Long Name | Rapport Therapeutics, Inc. |
| Market | us_market |
| Market Cap | 2,339,901,184 |
| Market State | CLOSED |
| Max Age | 86,400 |
| Message Board Id | finmb_1828746377 |
| Most Recent Quarter | 1,782,777,600 |
| Net Income To Common | -137,160,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 2,438,736,277 |
| Number Of Analyst Opinions | 12 |
| Open | 50.0 |
| Operating Cashflow | -96,682,000 |
| Operating Margins | -7.6758003 |
| Overall Risk | 7 |
| Payout Ratio | 0.0 |
| Phone | 857 321 8020 |
| Post Market Change | 0.0 |
| Post Market Change Percent | 0.0 |
| Post Market Price | 48.77 |
| Post Market Time | 1,787,959,806 |
| Previous Close | 50.83 |
| Price Eps Current Year | -11.914505 |
| Price Hint | 2 |
| Price To Book | 5.5301056 |
| Price To Sales Trailing12 Months | 116.995056 |
| Profit Margins | 0.0 |
| Quick Ratio | 15.352 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | strong_buy |
| Recommendation Mean | 1.07692 |
| Region | US |
| Regular Market Change | -2.06 |
| Regular Market Change Percent | -4.05273 |
| Regular Market Day High | 50.6751 |
| Regular Market Day Low | 48.37 |
| Regular Market Day Range | 48.37 - 50.6751 |
| Regular Market Open | 50.0 |
| Regular Market Previous Close | 50.83 |
| Regular Market Price | 48.77 |
| Regular Market Time | 1,787,947,200 |
| Regular Market Volume | 332,729 |
| Return On Assets | -0.25776 |
| Return On Equity | -0.39963 |
| Revenue Per Share | 0.445 |
| Sand P52 Week Change | 0.20504117 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 47,978,286 |
| Shares Percent Shares Out | 0.0464 |
| Shares Short | 2,225,618 |
| Shares Short Previous Month Date | 1,784,073,600 |
| Shares Short Prior Month | 2,690,734 |
| Short Name | Rapport Therapeutics, Inc. |
| Short Percent Of Float | 0.0734 |
| Short Ratio | 7.33 |
| Source Interval | 15 |
| State | MA |
| Symbol | RAPP |
| Target High Price | 80.0 |
| Target Low Price | 50.0 |
| Target Mean Price | 62.04833 |
| Target Median Price | 59.0 |
| Total Cash | 436,076,992 |
| Total Cash Per Share | 9.089 |
| Total Debt | 10,105,000 |
| Total Revenue | 20,000,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -3.03 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 34.11645 |
| Two Hundred Day Average Change | 14.653549 |
| Two Hundred Day Average Change Percent | 0.42951563 |
| Type Disp | Equity |
| Volume | 332,729 |
| Website | https://www.rapportrx.com |
| Zip | 2,110 |