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Rapport Therapeutics, Inc. (RAPP)

Healthcare | Biotechnology | Boston, United States | NasdaqGM
36.27 USD -0.87 (-2.342%) ⇩ (April 21, 2026, 12:05 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, 1:20 a.m. EDT

RAPP is a difficult high-risk venture play where recent monster performance (up ~280% YTD) has coincided with significant insider selling, creating a "crowded trade" risk despite strong analyst upgrades. The stock lacks fundamental safety (negative earnings, no dividend) and faces the typical binary risk of biotech developers awaiting Phase 2a data. While the Price-to-Book ratio above 3.5x suggests the market is pricing in massive success, the recent insider offloading of millions of dollars in shares is a major red flag for sustainability, capping the near-term upside potential.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.089377
AutoARIMA0.092151
AutoETS0.093000
MSTL0.095644

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 26%
H-stat 15.14
Ljung-Box p 0.000
Jarque-Bera p 0.011
Excess Kurtosis 0.63
Attribute Value
Sector Healthcare
Debt to Equity Ratio 2.37
Market Cap 1,733,450,112
Forward P/E -8.64
Website https://www.rapportrx.com

As of April 19, 2026, 1:20 a.m. EDT: Options sentiment shows high downside protection via May 2026 puts (heavy OI at $30, $35 strikes), indicating a 'high' floor expectation around 30-35 despite the current price of ~39.71. Call flow is skewed towards the money and ITM (40.0, 42.5), suggesting a non-aggressive upside bet. November options are virtually inert with volume exceeding open interest at the ATM ($40 call), hinting at potential supportive buying pressure. Implied volatility is moderate (under 1.2), suggesting a market that believes moderate moves are priced in, but insider selling hasn't spiked IV significantly yet.


Info Dump

Attribute Value
52 Week Change 2.2155845
Address1 99 High Street
Address2 Suite 2100
All Time High 42.269
All Time Low 6.43
Ask 45.91
Ask Size 2
Audit Risk 7
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 398,170
Average Daily Volume3 Month 345,680
Average Volume 345,680
Average Volume10Days 398,170
Bid 26.55
Bid Size 2
Board Risk 7
Book Value 10.145
City Boston
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 36.27
Current Ratio 26.173
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 37.13
Day Low 35.71
Debt To Equity 2.37
Display Name Rapport Therapeutics
Earnings Timestamp 1,773,145,800
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -124,082,000
Ebitda Margins 0.0
Enterprise To Ebitda -10.445
Enterprise Value 1,295,974,912
Eps Current Year -3.36571
Eps Forward -4.2
Eps Trailing Twelve Months -2.86
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 30.3802
Fifty Day Average Change 5.889801
Fifty Day Average Change Percent 0.19386972
Fifty Two Week Change Percent 221.55846
Fifty Two Week High 42.269
Fifty Two Week High Change -5.9990005
Fifty Two Week High Change Percent -0.14192435
Fifty Two Week Low 7.73
Fifty Two Week Low Change 28.54
Fifty Two Week Low Change Percent 3.6921089
Fifty Two Week Range 7.73 - 42.269
Financial Currency USD
First Trade Date Milliseconds 1,717,767,000,000
Float Shares 30,787,736
Forward Eps -4.2
Forward P E -8.635715
Free Cashflow -54,166,876
Full Exchange Name NasdaqGM
Full Time Employees 84
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.046040002
Held Percent Institutions 1.0763
Implied Shares Outstanding 47,792,943
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,024-06-07
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.
Long Name Rapport Therapeutics, Inc.
Market us_market
Market Cap 1,733,450,112
Market State REGULAR
Max Age 86,400
Message Board Id finmb_1828746377
Most Recent Quarter 1,767,139,200
Net Income To Common -111,483,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,777,419,550
Number Of Analyst Opinions 10
Open 36.93
Operating Cashflow -87,473,000
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 857 321 8020
Previous Close 37.14
Price Eps Current Year -10.77633
Price Hint 2
Price To Book 3.57516
Profit Margins 0.0
Quick Ratio 25.751
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.09091
Region US
Regular Market Change -0.86999893
Regular Market Change Percent -2.342485
Regular Market Day High 37.13
Regular Market Day Low 35.71
Regular Market Day Range 35.71 - 37.13
Regular Market Open 36.93
Regular Market Previous Close 37.14
Regular Market Price 36.27
Regular Market Time 1,776,787,538
Regular Market Volume 173,045
Return On Assets -0.189
Return On Equity -0.28221
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 47,792,943
Shares Percent Shares Out 0.0805
Shares Short 3,849,519
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 3,513,015
Short Name Rapport Therapeutics, Inc.
Short Percent Of Float 0.1462
Short Ratio 10.6
Source Interval 15
State MA
Symbol RAPP
Target High Price 80.0
Target Low Price 40.0
Target Mean Price 53.6
Target Median Price 50.5
Total Cash 490,539,008
Total Cash Per Share 10.264
Total Debt 11,484,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.86
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 25.31345
Two Hundred Day Average Change 10.956551
Two Hundred Day Average Change Percent 0.43283513
Type Disp Equity
Volume 173,045
Website https://www.rapportrx.com
Zip 2,110