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Rapport Therapeutics, Inc. (RAPP)

Healthcare | Biotechnology | Boston, United States | NasdaqGM
28.99 USD -1.16 (-3.847%) ⇩ (Oct. 13, 2026, 4 p.m. EDT)

Short-term:★★☆☆☆Long-term:★★☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 6:54 a.m. EDT

The investment case here is defined by a stark disconnect between the company's financial reality and the market's speculative fervor. Fundamentally, Rapport Therapeutics is a distressed biotech play with negative earnings, negative free cash flow, and gross margins in the red. The balance sheet shows significant burn, and the forward P/E is meaningless due to losses. There is no dividend to provide income, and the recent price action shows a sharp deterioration from September highs, trading significantly below the 50-day moving average. However, the options market is telling a completely different story. The sheer volume of new call buying at distant strikes (45 and 55) for late 2027 implies that traders are betting on a 'moonshot' scenario where the stock triples or quadruples. This aggressive positioning likely stems from anticipation of the Phase 3 trial results mentioned in the news headlines. While the statistical forecasting models are useless here due to low reliability, the options flow acts as a contrarian signal: retail and speculative capital are ignoring the terrible fundamentals and betting entirely on a clinical success. For the long term, the risks are severe; if the trials fail, the stock could go to zero given the cash burn. For the short term, the gap between the current price (~$30) and the analyst mean target (~$63) represents a massive gap, but the recent weekly decline suggests profit-taking is occurring. The rating is bearish on fundamentals but acknowledges the high-conviction speculative bet being placed by the options crowd.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.107627
AutoETS0.110242
AutoARIMA0.111887
MSTL0.112885

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 28%
H-stat 4.03
Ljung-Box p 0.000
Jarque-Bera p 0.018
Excess Kurtosis 0.14
Attribute Value
Sector Healthcare
Debt to Equity Ratio 2.389
Revenue per Share 0.445
Market Cap 1,390,890,496
Forward P/E -5.70
Beta 1.22
Website https://www.rapportrx.com

As of Oct. 10, 2026, 6:54 a.m. EDT: Speculators are aggressively positioning for a massive upside move, evidenced by heavy new volume flowing into deep out-of-the-money calls at strikes 45 and 55 for February 2027 expiration. This 'lottery ticket' buying suggests a belief in a binary event or a significant catalyst that could drive the price well above $50. Conversely, put writing is concentrated at lower strikes (20-30), indicating a floor is expected, but the overwhelming capital allocation is on the upside. Implied volatility remains extremely low across all expirations, suggesting the market is pricing in a calm environment despite the speculative call flow.


Info Dump

Attribute Value
52 Week Change 0.21181667
Address1 99 High Street
Address2 Suite 2100
All Time High 52.93
All Time Low 6.43
Ask 52.54
Ask Size 2
Audit Risk 5
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 317,180
Average Daily Volume3 Month 351,778
Average Volume 351,778
Average Volume10Days 317,180
Beta 1.219
Bid 30.56
Bid Size 2
Board Risk 6
Book Value 8.819
City Boston
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 28.99
Current Ratio 15.721
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 30.01
Day Low 28.6828
Debt To Equity 2.389
Display Name Rapport Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,785,933,000
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda -152,556,000
Ebitda Margins 0.0
Enterprise To Ebitda -6.325
Enterprise To Revenue 48.246
Enterprise Value 964,918,528
Eps Current Year -4.087
Eps Forward -5.087
Eps Trailing Twelve Months -3.03
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 42.2109
Fifty Day Average Change -13.2209
Fifty Day Average Change Percent -0.31321058
Fifty Two Week Change Percent 21.181667
Fifty Two Week High 52.93
Fifty Two Week High Change -23.94
Fifty Two Week High Change Percent -0.45229548
Fifty Two Week Low 23.75
Fifty Two Week Low Change 5.24
Fifty Two Week Low Change Percent 0.22063157
Fifty Two Week Range 23.75 - 52.93
Financial Currency USD
First Trade Date Milliseconds 1,717,767,000,000
Float Shares 32,398,777
Forward Eps -5.087
Forward P E -5.69884
Free Cashflow -56,016,500
Full Exchange Name NasdaqGM
Full Time Employees 84
Fullday Change 0.0
Fullday Change Percent 0.0
Fullday Price 28.99
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins -1.0939
Gross Profits -21,878,000
Has Pre Post Market Data 1
Held Percent Insiders 0.03889
Held Percent Institutions 1.09008
Implied Shares Outstanding 47,978,286
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,024-06-07
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.
Long Name Rapport Therapeutics, Inc.
Market us_market
Market Cap 1,390,890,496
Market State PRE
Max Age 86,400
Message Board Id finmb_1828746377
Most Recent Quarter 1,782,777,600
Net Income To Common -137,160,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,643,256,295
Number Of Analyst Opinions 13
Open 30.0
Operating Cashflow -96,682,000
Operating Margins -7.6758003
Overall Risk 7
Phone 857 321 8020
Pre Market Change 0.0
Pre Market Change Percent 0.0
Pre Market Price 28.99
Pre Market Time 1,791,966,942
Previous Close 30.15
Price Eps Current Year -7.0932226
Price Hint 2
Price To Book 3.2872207
Price To Sales Trailing12 Months 69.544525
Profit Margins 0.0
Quick Ratio 15.352
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.07143
Region US
Regular Market Change -1.16
Regular Market Change Percent -3.84743
Regular Market Day High 30.01
Regular Market Day Low 28.6828
Regular Market Day Range 28.6828 - 30.01
Regular Market Open 30.0
Regular Market Previous Close 30.15
Regular Market Price 28.99
Regular Market Time 1,791,921,600
Regular Market Volume 309,975
Return On Assets -0.25776
Return On Equity -0.39963
Revenue Per Share 0.445
Sand P52 Week Change 0.17502642
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 47,978,286
Shares Percent Shares Out 0.066599995
Shares Short 3,194,008
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 2,233,723
Short Name Rapport Therapeutics, Inc.
Short Percent Of Float 0.105399996
Short Ratio 6.71
Source Interval 15
State MA
Symbol RAPP
Target High Price 80.0
Target Low Price 50.0
Target Mean Price 63.04462
Target Median Price 62.0
Total Cash 436,076,992
Total Cash Per Share 9.089
Total Debt 10,105,000
Total Revenue 20,000,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -3.03
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 35.79775
Two Hundred Day Average Change -6.807749
Two Hundred Day Average Change Percent -0.19017254
Type Disp Equity
Volume 309,975
Website https://www.rapportrx.com
Zip 2,110