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Rani Therapeutics Holdings, Inc. (RANI)

Healthcare | Biotechnology | San Jose, United States | NasdaqGM
0.84 USD -0.01 (-1.662%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 0.87 +0.03 (3.607%) ⇧ (Aug. 28, 2026, 7:44 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:13 a.m. EDT

The investment case here is structurally broken. The company has endured four consecutive years of negative annual returns, culminating in a catastrophic 96% cumulative decline over the last four years. This is not a temporary correction; the market has repeatedly punished the stock, driving it from highs above $17 to sub-$1 levels. Fundamentally, the business is hemorrhaging cash with negative operating margins and no revenue growth to speak of. While insiders have recently bought shares, likely due to the depressed valuation, this does not alter the reality that the underlying asset is deteriorating rapidly. The analyst consensus of 'strong buy' with a $7.20 target is a dangerous illusion given the lack of earnings power and the brutal historical performance. With no dividend to provide income and a balance sheet that cannot sustain operations without further dilution, this is a clear avoid.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.085855
AutoARIMA0.092793
AutoETS0.100484
AutoTheta0.104225

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 38%
H-stat 0.50
Ljung-Box p 0.000
Jarque-Bera p 0.503
Excess Kurtosis 0.04
Attribute Value
Sector Healthcare
Debt to Equity Ratio 7.396
Revenue per Share 0.035
Market Cap 118,036,392
Forward P/E -4.42
Beta 0.70
Website https://www.ranitherapeutics.com

As of Aug. 22, 2026, 4:13 a.m. EDT: Speculators are positioning defensively with heavy put volume relative to calls, particularly at strikes significantly above the current price (e.g., $2.00 puts showing top open interest). While there is some call activity at near-the-money levels, the open interest concentration in out-of-the-money puts suggests a dominant bearish sentiment and a fear of further downside rather than a bullish breakout expectation.


Info Dump

Attribute Value
52 Week Change 0.832618
Address1 2,051 Ringwood Avenue
All Time High 36.27
All Time Low 0.387
Ask 1.0
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 892,660
Average Daily Volume3 Month 846,441
Average Volume 846,441
Average Volume10Days 892,660
Beta 0.695
Bid 0.76
Bid Size 9
Book Value 0.285
City San Jose
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 0.84
Current Ratio 5.313
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 0.861
Day Low 0.8361
Debt To Equity 7.396
Display Name Rani Therapeutics
Earnings Call Timestamp End 1,774,557,000
Earnings Call Timestamp Start 1,774,557,000
Earnings Timestamp End 1,793,908,800
Earnings Timestamp Start 1,793,908,800
Ebitda -32,237,000
Ebitda Margins 0.0
Enterprise To Ebitda -1.733
Enterprise To Revenue 11.455
Enterprise Value 55,865,968
Eps Current Year -0.17333
Eps Forward -0.19
Eps Trailing Twelve Months -0.13
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 0.78078
Fifty Day Average Change 0.059219956
Fifty Day Average Change Percent 0.07584717
Fifty Two Week Change Percent 83.2618
Fifty Two Week High 3.87
Fifty Two Week High Change -3.03
Fifty Two Week High Change Percent -0.78294575
Fifty Two Week Low 0.44
Fifty Two Week Low Change 0.39999998
Fifty Two Week Low Change Percent 0.9090909
Fifty Two Week Range 0.44 - 3.87
Financial Currency USD
First Trade Date Milliseconds 1,627,651,800,000
Float Shares 83,498,416
Forward Eps -0.19
Forward P E -4.4210525
Free Cashflow -8,874,375
Full Exchange Name NasdaqGM
Full Time Employees 69
Fullday Change -0.0142
Fullday Change Percent -1.66238
Fullday Price 0.8703
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 4,877,000
Has Pre Post Market Data 1
Held Percent Insiders 0.04908
Held Percent Institutions 0.46805
Implied Shares Outstanding 140,519,513
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-30
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Rani Therapeutics Holdings, Inc. operates as a clinical stage biotherapeutics company, focusing on technologies to enable the administration of biologics and drugs orally for patients, physicians, and healthcare systems with a alternative to painful injections in the United States. The company develops the RaniPill capsule, a drug-agnostic oral delivery platform to deliver a variety of drug substances, including oligonucleotides, peptides, proteins, and antibodies. Its product pipeline includes RT-105, an anti-TNF-alpha antibody that is in preclinical studies to treat rheumatoid arthritis; RT-116 which is in discovery stage for the treatment of obesity; RT-117 for rare diseases; and RT-111, an ustekinumab biosimilar for the treatment of various inflammatory conditions. The company has a collaboration agreement with ProGen Co., Ltd. for the o-development and commercialization of RT-114 to treat obesity; Chugai Pharmaceutical Co., Ltd. to commercialize the Chugai Product combining Chugai's Compound, which is in development for hemophilia, and the RaniPill HC oral delivery device for use in humans; and has a research and development collaboration with PegBio Co., Ltd. to expand obesity pipeline across multiple novel candidates. Rani Therapeutics Holdings, Inc. was founded in 2012 and is headquartered in San Jose, California.
Long Name Rani Therapeutics Holdings, Inc.
Market us_market
Market Cap 118,036,392
Market State CLOSED
Max Age 86,400
Message Board Id finmb_242425883
Most Recent Quarter 1,782,777,600
Net Income To Common -30,141,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 98,053,503
Number Of Analyst Opinions 5
Open 0.86
Operating Cashflow -20,292,000
Operating Margins -5.16862
Payout Ratio 0.0
Phone 408 457 3700
Post Market Change 0.030300021
Post Market Change Percent 3.6071455
Post Market Price 0.8703
Post Market Time 1,787,960,672
Previous Close 0.8542
Price Eps Current Year -4.846247
Price Hint 4
Price To Book 2.9473684
Price To Sales Trailing12 Months 24.202663
Profit Margins 0.0
Quick Ratio 5.23
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.0142
Regular Market Change Percent -1.66238
Regular Market Day High 0.861
Regular Market Day Low 0.8361
Regular Market Day Range 0.8361 - 0.861
Regular Market Open 0.86
Regular Market Previous Close 0.8542
Regular Market Price 0.84
Regular Market Time 1,787,947,200
Regular Market Volume 371,267
Return On Assets -0.52994996
Return On Equity -1.72147
Revenue Per Share 0.035
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 115,424,960
Shares Percent Shares Out 0.070700005
Shares Short 8,159,153
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 8,845,231
Short Name Rani Therapeutics Holdings, Inc
Short Percent Of Float 0.0726
Short Ratio 8.89
Source Interval 15
State CA
Symbol RANI
Target High Price 11.0
Target Low Price 5.0
Target Mean Price 7.2
Target Median Price 6.0
Total Cash 53,391,000
Total Cash Per Share 0.463
Total Debt 3,549,000
Total Revenue 4,877,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.13
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.11207
Two Hundred Day Average Change -0.27207
Two Hundred Day Average Change Percent -0.24465187
Type Disp Equity
Volume 371,267
Website https://www.ranitherapeutics.com
Zip 95,131