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Quince Therapeutics, Inc. (QNCX)

Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
31.73 USD +2.37 (8.072%) ⇧ (Oct. 9, 2026, 4 p.m. EDT)

Short-term:★☆☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 3:55 a.m. EDT

This biotech stock is currently trapped in a severe structural decline, having lost over 92% of its value over the past six years despite a recent annual rebound. While the company recently presented positive Phase 2a data for its LAM-001 therapy and secured a merger deal, the balance sheet remains fundamentally broken with negative book value, massive losses, and no free cash flow. The market has correctly priced these risks, and the recent price surge appears to be a volatile, speculative reaction rather than a sustainable recovery given the lack of institutional support. With no dividend to provide income and a statistical forecast leaning slightly negative due to low confidence, the immediate outlook remains perilous for capital preservation.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.262315
AutoARIMA0.267547
AutoETS0.270319
AutoTheta0.270477

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 37%
H-stat 0.64
Ljung-Box p 0.000
Jarque-Bera p 0.532
Excess Kurtosis 0.05
Attribute Value
Sector Healthcare
Market Cap 32,271,408
Forward P/E -6.78
Beta 1.33
Previous Name Cortexyme, Inc.
Website https://quincetx.com

As of Oct. 10, 2026, 3:55 a.m. EDT: Options activity shows negligible volume and open interest across all strikes for both calls and puts. The lack of liquidity and positioning data suggests a complete absence of speculative interest or directional bets from market participants, rendering the options chain useless for gauging near-term sentiment.


Info Dump

Attribute Value
52 Week Change -0.91067207
Address1 611 Gateway Boulevard
Address2 Suite 273
All Time High 24,396.0
All Time Low 15.1
Ask 34.15
Ask Size 7
Audit Risk 9
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 49,870
Average Daily Volume3 Month 29,957
Average Volume 29,957
Average Volume10Days 49,870
Beta 1.332
Bid 20.67
Bid Size 2
Board Risk 7
Book Value -34.731
City South San Francisco
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 31.73
Current Ratio 14.519
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 37.0
Day Low 29.8396
Display Name Quince Therapeutics
Dividend Yield 0.0
Earnings Timestamp 1,786,710,600
Earnings Timestamp End 1,794,513,600
Earnings Timestamp Start 1,794,513,600
Ebitda -60,647,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.991
Enterprise Value 60,101,408
Eps Current Year -3.65333
Eps Forward -4.68333
Eps Trailing Twelve Months -214.01
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 30.7868
Fifty Day Average Change 0.94319916
Fifty Day Average Change Percent 0.030636478
Fifty Two Week Change Percent -91.06721
Fifty Two Week High 910.0
Fifty Two Week High Change -878.27
Fifty Two Week High Change Percent -0.9651319
Fifty Two Week Low 15.1
Fifty Two Week Low Change 16.63
Fifty Two Week Low Change Percent 1.1013244
Fifty Two Week Range 15.1 - 910.0
Financial Currency USD
First Trade Date Milliseconds 1,557,408,600,000
Float Shares 679,683
Forward Eps -4.68333
Forward P E -6.7750936
Free Cashflow -25,748,376
Full Exchange Name NasdaqGS
Full Time Employees 38
Fullday Change 2.369999
Fullday Change Percent 8.072204
Fullday Price 31.73
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.02901
Held Percent Institutions 0.34495
Implied Shares Outstanding 1,017,063
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,782,777,600
Last Split Factor 1:20
Long Business Summary Quince Therapeutics, Inc., a biotechnology company, focuses on acquiring, developing, and commercializing therapeutics for patients with debilitating and rare diseases. The company's lead asset candidature comprises eDSP, which is in Phase 3, for the treatment of rare pediatric neurodegenerative disease, including A-T, an inherited autosomal recessive neurodegenerative and immunodeficiency disorder caused by mutations in ATM gene. Its AIDE technology platform, a drug/device combination platform that uses an automated process to encapsulate a drug into a patient's own red blood cells, as well as consist of an automated equipment the RCL, a sterile single-use consumable treatment kit comprising kit medical devices, syringe kit, and process solutions. The company was formerly known as Cortexyme, Inc. and changed its name to Quince Therapeutics, Inc. in August 2022. The company was incorporated in 2012 and is headquartered in South San Francisco, California.
Long Name Quince Therapeutics, Inc.
Market us_market
Market Cap 32,271,408
Market State POST
Max Age 86,400
Message Board Id finmb_266230063
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-10-12
Net Income To Common -92,476,000
New Symbol IRLA
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 30,003,358
Number Of Analyst Opinions 8
Open 30.5
Operating Cashflow -46,923,000
Operating Margins 0.0
Overall Risk 8
Phone 415 910 5717
Prev Name Cortexyme, Inc.
Previous Close 29.36
Price Eps Current Year -8.685226
Price Hint 2
Price To Book -0.91359305
Profit Margins 0.0
Quick Ratio 14.233
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.44444
Region US
Regular Market Change 2.37
Regular Market Change Percent 8.0722
Regular Market Day High 37.0
Regular Market Day Low 29.8396
Regular Market Day Range 29.8396 - 37.0
Regular Market Open 30.5
Regular Market Previous Close 29.36
Regular Market Price 31.73
Regular Market Time 1,791,576,000
Regular Market Volume 138,744
Return On Assets -0.31508
Return On Equity -1.5384101
Sand P52 Week Change 0.16207206
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 1,017,063
Shares Percent Shares Out 0.0589
Shares Short 59,944
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 56,989
Short Name Quince Therapeutics, Inc.
Short Percent Of Float 0.0591
Short Ratio 2.92
Source Interval 15
State CA
Symbol QNCX
Target High Price 98.0
Target Low Price 65.0
Target Mean Price 75.0
Target Median Price 71.0
Total Cash 115,981,000
Total Cash Per Share 114.035
Total Debt 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -214.01
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 85.11895
Two Hundred Day Average Change -53.38895
Two Hundred Day Average Change Percent -0.62722754
Type Disp Equity
Volume 138,744
Website https://quincetx.com
Zip 94,080