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PolyPid Ltd. (PYPD)

Healthcare | Biotechnology | Petah Tikva, Israel | NasdaqCM
5.07 USD -0.05 (-0.977%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 5.17 +0.10 (1.972%) ⇧ (Aug. 28, 2026, 7:30 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 3:43 a.m. EDT

The investment case here is fundamentally broken. While the company boasts a 'strong buy' analyst recommendation and a target price nearly triple the current level, these metrics ignore the reality of a biotech firm burning through cash with no path to profitability. The fundamentals are catastrophic: the stock has lost 99% of its value over five years, and the most recent annual return was a crushing -94.8%. This is not a value trap; it is a business in freefall where the market has correctly priced out the risk of permanent capital loss. The recent price uptick is merely a technical bounce off multi-year lows, not a sign of recovery. With negative free cash flow, negative equity, and no dividend to cushion the blow, there is no margin of safety. The options market confirms this despair, with traders buying deep out-of-the-money puts for 2027 expiration, betting on further declines. Until the company demonstrates sustained revenue growth and a return to positive cash flows, this remains a speculative gamble on a miracle, not an investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.081312
AutoARIMA0.083589
AutoETS0.084412
MSTL0.086247

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 40%
H-stat 0.34
Ljung-Box p 0.000
Jarque-Bera p 0.126
Excess Kurtosis -0.17
Attribute Value
Sector Healthcare
Debt to Equity Ratio 29.176
Market Cap 102,980,656
Forward P/E -4.13
Beta 1.39
Website https://www.polypid.com

As of Aug. 22, 2026, 3:43 a.m. EDT: Speculators are heavily positioning for downside protection with massive open interest in out-of-the-money puts expiring in early 2027, while call volume remains negligible. The skew suggests a market consensus expecting further price compression rather than a rally.


Info Dump

Attribute Value
52 Week Change 0.5014663
Address1 18 Hasivim Street
All Time High 583.5
All Time Low 2.3
Ask 6.47
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 125,240
Average Daily Volume3 Month 223,450
Average Volume 223,450
Average Volume10Days 125,240
Beta 1.39
Bid 3.6
Bid Size 2
Book Value 0.265
City Petah Tikva
Compensation As Of Epoch Date 1,767,139,200
Country Israel
Crypto Tradeable 0
Currency USD
Current Price 5.07
Current Ratio 1.346
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 5.13
Day Low 4.985
Debt To Equity 29.176
Display Name PolyPid
Earnings Call Timestamp End 1,786,537,800
Earnings Call Timestamp Start 1,786,537,800
Earnings Timestamp 1,786,537,800
Earnings Timestamp End 1,794,400,200
Earnings Timestamp Start 1,794,400,200
Ebitda -30,118,000
Ebitda Margins 0.0
Enterprise To Ebitda -3.254
Enterprise Value 97,989,656
Eps Current Year -0.89
Eps Forward -1.2275
Eps Trailing Twelve Months -1.3
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 4.7995
Fifty Day Average Change 0.27050018
Fifty Day Average Change Percent 0.056360077
Fifty Two Week Change Percent 50.14663
Fifty Two Week High 5.73
Fifty Two Week High Change -0.65999985
Fifty Two Week High Change Percent -0.11518322
Fifty Two Week Low 3.06
Fifty Two Week Low Change 2.0100002
Fifty Two Week Low Change Percent 0.65686285
Fifty Two Week Range 3.06 - 5.73
Financial Currency USD
First Trade Date Milliseconds 1,593,178,200,000
Float Shares 12,163,295
Forward Eps -1.2275
Forward P E -4.1303463
Free Cashflow -17,364,124
Full Exchange Name NasdaqCM
Full Time Employees 69
Fullday Change -0.0499997
Fullday Change Percent -0.976557
Fullday Price 5.17
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.17789
Held Percent Institutions 0.34552
Implied Shares Outstanding 20,311,766
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-06-26
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,695,254,400
Last Split Factor 1:30
Long Business Summary PolyPid Ltd., a biopharmaceutical company, developing targeted, locally administered, and prolonged-release therapeutics using its proprietary polymer-lipid encapsulation matrix (PLEX) technology to address unmet medical needs. Its lead product candidate is D-PLEX100, which is in a pivotal Phase 3 confirmatory trial for prevention of surgical site infections (SSIs) in patients undergoing abdominal colorectal surgery with large incisions. The company is also developing OncoPLEX, which is in preclinical stage for the treatment of intra-tumoral cancer. The company has a research and development collaboration with ImmunoGenesis, Inc. for the development of formulations to treat solid tumors. PolyPid Ltd. was incorporated in 2008 and is headquartered in Petah Tikva, Israel.
Long Name PolyPid Ltd.
Market us_market
Market Cap 102,980,656
Market State CLOSED
Max Age 86,400
Message Board Id finmb_49223295
Most Recent Quarter 1,782,777,600
Net Income To Common -31,501,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 103,590,006
Number Of Analyst Opinions 4
Open 5.13
Operating Cashflow -29,003,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 972 7 4719 5700
Post Market Change 0.099999905
Post Market Change Percent 1.9723847
Post Market Price 5.17
Post Market Time 1,787,959,806
Previous Close 5.12
Price Eps Current Year -5.6966295
Price Hint 2
Price To Book 19.132076
Profit Margins 0.0
Quick Ratio 0.994
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change -0.0499997
Regular Market Change Percent -0.976557
Regular Market Day High 5.13
Regular Market Day Low 4.985
Regular Market Day Range 4.985 - 5.13
Regular Market Open 5.13
Regular Market Previous Close 5.12
Regular Market Price 5.07
Regular Market Time 1,787,947,200
Regular Market Volume 63,535
Return On Assets -0.74625
Return On Equity -2.4359
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 20,311,766
Shares Percent Shares Out 0.0114
Shares Short 231,379
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 283,206
Short Name PolyPid Ltd.
Short Percent Of Float 0.0152
Short Ratio 0.81
Source Interval 15
Symbol PYPD
Target High Price 14.0
Target Low Price 8.0
Target Mean Price 11.75
Target Median Price 12.5
Total Cash 6,563,000
Total Cash Per Share 0.323
Total Debt 1,572,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.3
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.459925
Two Hundred Day Average Change 0.610075
Two Hundred Day Average Change Percent 0.13679041
Type Disp Equity
Volume 63,535
Website https://www.polypid.com
Zip 4,959,376