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PolyPid Ltd. (PYPD)

Healthcare | Biotechnology | Petah Tikva, Israel | NasdaqCM
5.04 USD -0.19 (-3.633%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★☆☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 3:49 a.m. EDT

The investment case here is effectively nonexistent due to a catastrophic multi-year decline. The stock has lost 99.2% of its value over the last five years, with every single year showing negative returns. This is not a temporary setback; it is a structural implosion where the market has repeatedly rejected the business model. Fundamentals confirm the doom: the company is burning cash with negative returns on equity and assets, trading at a negative forward P/E because it generates no profit. While the pipeline has some FDA milestones ahead, the balance sheet is fragile, and the stock trades at a premium to book value despite having no earnings power. There is no dividend to cushion the blow, and the options market is screaming 'sell' with heavy put buying and no speculative call interest. Even with a high analyst target price, the math suggests the current price is a value trap rather than a bargain, as the business quality has deteriorated so severely that the market refuses to assign it a higher valuation. Avoid this security entirely.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.034290
MSTL0.047705
AutoETS0.055348
AutoARIMA0.058859

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 44%
H-stat 1.88
Ljung-Box p 0.000
Jarque-Bera p 0.529
Excess Kurtosis -0.73
Attribute Value
Sector Healthcare
Debt to Equity Ratio 26.686
Market Cap 96,637,352
Forward P/E -4.02
Beta 1.40
Website https://www.polypid.com

As of July 11, 2026, 3:49 a.m. EDT: Speculators are overwhelmingly bearish, with massive open interest in out-of-the-money puts (100 contracts at $5.00 for November expiration) and zero call volume beyond the immediate term. The call market shows heavy positioning in the money against the strike, while put writers are active, suggesting a strong consensus expectation of further downside or a lack of catalysts to drive a rally.


Info Dump

Attribute Value
52 Week Change 0.44000006
Address1 18 Hasivim Street
All Time High 583.5
All Time Low 2.3
Ask 6.47
Ask Size 2
Average Daily Volume10 Day 291,300
Average Daily Volume3 Month 142,144
Average Volume 142,144
Average Volume10Days 291,300
Beta 1.4
Bid 3.8
Bid Size 2
Book Value 0.458
City Petah Tikva
Compensation As Of Epoch Date 1,767,139,200
Country Israel
Crypto Tradeable 0
Currency USD
Current Price 5.04
Current Ratio 1.782
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 5.32
Day Low 5.0
Debt To Equity 26.686
Display Name PolyPid
Earnings Call Timestamp End 1,778,675,400
Earnings Call Timestamp Start 1,778,675,400
Earnings Timestamp 1,778,675,400
Earnings Timestamp End 1,786,537,800
Earnings Timestamp Start 1,786,537,800
Ebitda -31,731,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.776
Enterprise Value 88,071,352
Eps Current Year -1.4275
Eps Forward -1.255
Eps Trailing Twelve Months -1.74
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 4.7618
Fifty Day Average Change 0.27820015
Fifty Day Average Change Percent 0.058423318
Fifty Two Week Change Percent 44.000008
Fifty Two Week High 5.615
Fifty Two Week High Change -0.5749998
Fifty Two Week High Change Percent -0.102404244
Fifty Two Week Low 3.06
Fifty Two Week Low Change 1.98
Fifty Two Week Low Change Percent 0.64705884
Fifty Two Week Range 3.06 - 5.615
Financial Currency USD
First Trade Date Milliseconds 1,593,178,200,000
Float Shares 10,905,065
Forward Eps -1.255
Forward P E -4.0159364
Full Exchange Name NasdaqCM
Full Time Employees 69
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.21228
Held Percent Institutions 0.34848
Implied Shares Outstanding 19,174,078
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-06-26
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,695,254,400
Last Split Factor 1:30
Long Business Summary PolyPid Ltd., a biopharmaceutical company, developing targeted, locally administered, and prolonged-release therapeutics using its proprietary polymer-lipid encapsulation matrix (PLEX) technology to address unmet medical needs. Its lead product candidate is D-PLEX100, which is in a pivotal Phase 3 confirmatory trial for prevention of surgical site infections (SSIs) in patients undergoing abdominal colorectal surgery with large incisions. The company is also developing OncoPLEX, which is in preclinical stage for the treatment of intra-tumoral cancer. The company has a research and development collaboration with ImmunoGenesis, Inc. for the development of formulations to treat solid tumors. PolyPid Ltd. was incorporated in 2008 and is headquartered in Petah Tikva, Israel.
Long Name PolyPid Ltd.
Market us_market
Market Cap 96,637,352
Market State PRE
Max Age 86,400
Message Board Id finmb_49223295
Most Recent Quarter 1,774,915,200
Net Income To Common -33,629,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 96,637,353
Number Of Analyst Opinions 4
Open 5.26
Operating Margins 0.0
Payout Ratio 0.0
Phone 972 7 4719 5700
Pre Market Change 0.03999996
Pre Market Change Percent 0.79365003
Pre Market Price 5.08
Pre Market Time 1,784,016,022
Previous Close 5.23
Price Eps Current Year -3.530648
Price Hint 2
Price To Book 11.004367
Profit Margins 0.0
Quick Ratio 1.548
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.19
Regular Market Change Percent -3.63289
Regular Market Day High 5.32
Regular Market Day Low 5.0
Regular Market Day Range 5.0 - 5.32
Regular Market Open 5.26
Regular Market Previous Close 5.23
Regular Market Price 5.04
Regular Market Time 1,783,972,800
Regular Market Volume 251,219
Return On Assets -1.1506801
Return On Equity -7.58606
Sand P52 Week Change 0.20365608
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 19,174,078
Shares Percent Shares Out 0.0044
Shares Short 84,501
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 138,198
Short Name PolyPid Ltd.
Short Percent Of Float 0.006
Short Ratio 0.49
Source Interval 15
Symbol PYPD
Target High Price 14.0
Target Low Price 9.0
Target Mean Price 12.25
Target Median Price 13.0
Total Cash 10,909,000
Total Cash Per Share 0.569
Total Debt 2,343,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.74
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.26075
Two Hundred Day Average Change 0.77925014
Two Hundred Day Average Change Percent 0.18289039
Type Disp Equity
Volume 251,219
Website https://www.polypid.com
Zip 4,959,376