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Personalis, Inc. (PSNL)

Healthcare | Diagnostics & Research | Fremont, United States | NasdaqGM
15.04 USD +0.97 (6.894%) ⇧ (July 13, 2026, 4 p.m. EDT)
After hours: 14.85 -0.19 (-0.193%) ⇩ (July 13, 2026, 7:51 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 6:20 a.m. EDT

The investment case for Personalis is currently bifurcated between a technical rebound and a deteriorating business reality. On the surface, the stock has staged a remarkable recovery, surging nearly 275% year-over-year to hit a 52-week high, which has triggered a 'strong buy' consensus among analysts despite the company burning cash. However, this optimism ignores the brutal multi-year trajectory: the stock has lost 74.5% of its value over the last six years, with four of those years seeing double-digit declines. The recent rally appears to be a speculative re-rating based on a single strong quarter rather than a restoration of sustainable profitability, evidenced by negative operating margins and free cash flow. While the short-term momentum is building as the price tests resistance near the $15 level, the underlying fundamentals remain deeply impaired. The options market reflects this uncertainty, betting on a choppy range rather than a decisive move higher. Until the company demonstrates a path to consistent positive cash flow and stabilizes its revenue growth beyond the recent anomaly, the long-term outlook remains severely compromised.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL_90 ✓0.240737
MSTL_90_1260.249911
MSTL0.332498
AutoETS0.333005
AutoARIMA0.334968
AutoTheta0.335127
MSTL_1260.336395

Forecast horizon: 60 days | Selected: MSTL_90

Forecast Reliability
Score 31%
H-stat 20.44
Ljung-Box p 0.000
Jarque-Bera p 0.104
Excess Kurtosis -1.34
Attribute Value
Sector Healthcare
Debt to Equity Ratio 15.222
Revenue per Share 0.691
Market Cap 1,575,005,312
Forward P/E -16.66
Beta 2.24
Profit Margins -148.11%
Website https://www.personalis.com

As of July 11, 2026, 6:20 a.m. EDT: Speculators are positioning for a range-bound outcome rather than a directional breakout. Call open interest is heavily concentrated at the $12.50 strike, acting as a barrier, while significant put open interest sits at $10.00 and $7.50. This 'sandwich' structure suggests traders expect the price to oscillate between these levels without breaking out immediately. The implied volatility is elevated relative to the deep out-of-the-money strikes, indicating fear of a drop to the lower support zone, yet the lack of deep ITM call volume dampens immediate bullish conviction.


Info Dump

Attribute Value
52 Week Change 1.1746523
Address1 6,600 Dumbarton Circle
All Time High 53.46
All Time Low 0.891
Ask 17.44
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 4,574,500
Average Daily Volume3 Month 3,080,786
Average Volume 3,080,786
Average Volume10Days 4,574,500
Beta 2.243
Bid 11.57
Bid Size 2
Board Risk 4
Book Value 2.433
City Fremont
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 15.04
Current Ratio 6.613
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 16.1499
Day Low 13.54
Debt To Equity 15.222
Display Name Personalis
Earnings Call Timestamp End 1,778,187,600
Earnings Call Timestamp Start 1,778,187,600
Earnings Timestamp 1,778,184,000
Earnings Timestamp End 1,785,960,000
Earnings Timestamp Start 1,785,960,000
Ebitda -92,692,000
Ebitda Margins -1.43675
Enterprise To Ebitda -14.894
Enterprise To Revenue 21.399
Enterprise Value 1,380,568,320
Eps Current Year -1.02429
Eps Forward -0.90286
Eps Trailing Twelve Months -1.02
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 752 1301
Fifty Day Average 9.6696
Fifty Day Average Change 5.3704004
Fifty Day Average Change Percent 0.5553902
Fifty Two Week Change Percent 117.46523
Fifty Two Week High 16.1499
Fifty Two Week High Change -1.1099005
Fifty Two Week High Change Percent -0.06872491
Fifty Two Week Low 3.84
Fifty Two Week Low Change 11.2
Fifty Two Week Low Change Percent 2.9166667
Fifty Two Week Range 3.84 - 16.1499
Financial Currency USD
First Trade Date Milliseconds 1,561,037,400,000
Float Shares 64,492,488
Forward Eps -0.90286
Forward P E -16.658175
Free Cashflow -42,353,248
Full Exchange Name NasdaqGM
Full Time Employees 259
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.13719
Gross Profits 8,851,000
Has Pre Post Market Data 1
Held Percent Insiders 0.26668
Held Percent Institutions 0.682
Implied Shares Outstanding 104,721,098
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for the detection of MRD; and NeXT Dx, a tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. In addition, the company performs whole exome sequencing of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing on human samples for research projects, such as population sequencing initiatives. Its services are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies, and for clinical trials, as well as tests are used by physicians to detect residual or recurrent cancer in patients, monitor cancer response to therapy, and uncover insights for therapy selection. The company's customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and cancer patients. The company has strategic collaboration with Tempus AI, Inc. to bring testing to colorectal cancer patients. Personalis, Inc. was incorporated in 2011 and is headquartered in Fremont, California.
Long Name Personalis, Inc.
Market us_market
Market Cap 1,575,005,312
Market State PREPRE
Max Age 86,400
Message Board Id finmb_139360745
Most Recent Quarter 1,774,915,200
Net Income To Common -95,552,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 1,472,378,637
Number Of Analyst Opinions 7
Open 13.885
Operating Cashflow -79,463,000
Operating Margins -2.07866
Overall Risk 7
Payout Ratio 0.0
Phone 650 752 1300
Post Market Change -0.19250011
Post Market Change Percent -1.2799209
Post Market Price 14.8475
Post Market Time 1,783,986,700
Previous Close 14.07
Price Eps Current Year -14.683342
Price Hint 2
Price To Book 6.1816683
Price To Sales Trailing12 Months 24.41301
Profit Margins -1.48108
Quick Ratio 6.307
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.42857
Region US
Regular Market Change 0.97
Regular Market Change Percent 6.8941
Regular Market Day High 16.1499
Regular Market Day Low 13.54
Regular Market Day Range 13.54 - 16.1499
Regular Market Open 13.885
Regular Market Previous Close 14.07
Regular Market Price 15.04
Regular Market Time 1,783,972,800
Regular Market Volume 10,664,135
Return On Assets -0.21405001
Return On Equity -0.41355
Revenue Growth -0.249
Revenue Per Share 0.691
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 104,721,098
Shares Percent Shares Out 0.108
Shares Short 11,306,678
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 12,825,386
Short Name Personalis, Inc.
Short Percent Of Float 0.1705
Short Ratio 3.11
Source Interval 15
State CA
Symbol PSNL
Target High Price 13.0
Target Low Price 10.0
Target Mean Price 11.42857
Target Median Price 11.0
Total Cash 233,218,000
Total Cash Per Share 2.227
Total Debt 38,781,000
Total Revenue 64,515,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.02
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 8.5748
Two Hundred Day Average Change 6.4652004
Two Hundred Day Average Change Percent 0.7539769
Type Disp Equity
Volume 10,664,135
Website https://www.personalis.com
Zip 94,555