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ProQR Therapeutics N.V. (PRQR)

Healthcare | Biotechnology | Leiden, Netherlands | NasdaqCM
1.78 USD -0.07 (-3.523%) ⇩ (April 21, 2026, 12:08 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 11:29 p.m. EDT

AI-driven drug discovery pipeline is igniting speculative zeal, evidenced by the 'strong_buy' analyst consensus and aggressive 2026 clinic targets. Technically, the stock rebounds above the 60-day SMA, confirming short-term momentum. However, this is a binary play on upcoming clinical data; the lack of dividend yield and negative fundamentals mean this remains a high-volatility venture rather than a wealth-building income vehicle.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.075478
AutoETS0.076787
AutoARIMA0.076788
AutoTheta0.133903

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 80%
H-stat 0.66
Ljung-Box p 0.000
Jarque-Bera p 0.513
Excess Kurtosis -0.63
Attribute Value
Sector Healthcare
Debt to Equity Ratio 32.333
Revenue per Share 0.155
Market Cap 187,015,888
Forward P/E -3.78
Beta 0.09
Profit Margins -258.05%
Website https://www.proqr.com

As of April 18, 2026, 11:29 p.m. EDT: Options market is highly skewed bullish, with net volume concentrated almost exclusively in the 2.5 strikes (Weakly OTM). The 05/15 and 07/17 expirations show significant new call volume at the 2.5 strike, creating new flow anchors. In contrast, put activity is negligible (only 1 net volume contract in July), indicating a lack of fear and weak downside protection. Bid-ask spreads and Volume/Ask imbalances suggest speculative positioning for a rapid move above the 2.0 PSW resistance zone.


Info Dump

Attribute Value
52 Week Change 0.36296296
Address1 Zernikedreef 9
All Time High 27.6
All Time Low 0.53
Ask 2.27
Ask Size 2
Average Analyst Rating 1.1 - Strong Buy
Average Daily Volume10 Day 741,940
Average Daily Volume3 Month 450,286
Average Volume 450,286
Average Volume10Days 741,940
Beta 0.093
Bid 1.33
Bid Size 2
Book Value 0.54827976
City Leiden
Compensation As Of Epoch Date 1,767,139,200
Country Netherlands
Crypto Tradeable 0
Currency USD
Current Price 1.775
Current Ratio 3.086
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 1.89
Day Low 1.7701
Debt To Equity 32.333
Display Name ProQR Therapeutics
Earnings Timestamp 1,773,318,600
Earnings Timestamp End 1,778,157,000
Earnings Timestamp Start 1,778,157,000
Ebitda -42,544,000
Ebitda Margins -2.60256
Enterprise To Ebitda -2.76
Enterprise To Revenue 7.183
Enterprise Value 117,415,360
Eps Forward -0.47
Eps Trailing Twelve Months -0.47
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.6536
Fifty Day Average Change 0.1214
Fifty Day Average Change Percent 0.07341558
Fifty Two Week Change Percent 36.296295
Fifty Two Week High 3.1
Fifty Two Week High Change -1.3249999
Fifty Two Week High Change Percent -0.42741933
Fifty Two Week Low 1.31
Fifty Two Week Low Change 0.46500003
Fifty Two Week Low Change Percent 0.35496187
Fifty Two Week Range 1.31 - 3.1
Financial Currency EUR
First Trade Date Milliseconds 1,411,047,000,000
Float Shares 64,346,109
Forward Eps -0.47
Forward P E -3.7765956
Free Cashflow -32,042,376
Full Exchange Name NasdaqCM
Full Time Employees 186
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 16,347,000
Has Pre Post Market Data 1
Held Percent Insiders 0.17665
Held Percent Institutions 0.50794
Implied Shares Outstanding 105,361,064
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs. Its lead product candidate, AX-0810, targets na-taurocholate cotransporting polypeptide (NTCP) for the treatment of cholestatic diseases. The company also develops AX-2402, which targets methyl CpG binding protein 2 mutations for Rett syndrome; AX-2911, which targets PNPLA3 for metabolic dysfunction-associated steatohepatitis; and AX-1412, which targets the B4GALT1 gene for cardiovascular diseases. It has a research and collaboration agreement with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.
Long Name ProQR Therapeutics N.V.
Market us_market
Market Cap 187,015,888
Market State REGULAR
Max Age 86,400
Message Board Id finmb_224193775
Most Recent Quarter 1,767,139,200
Net Income To Common -42,184,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 192,810,747
Number Of Analyst Opinions 8
Open 1.83
Operating Cashflow -52,791,000
Operating Margins -1.92897
Payout Ratio 0.0
Phone 31 88 166 7000
Previous Close 1.84
Price Hint 4
Price To Book 3.2373984
Price To Sales Trailing12 Months 11.44038
Profit Margins -2.5805302
Quick Ratio 3.005
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.125
Region US
Regular Market Change -0.06500006
Regular Market Change Percent -3.5232294
Regular Market Day High 1.89
Regular Market Day Low 1.7701
Regular Market Day Range 1.7701 - 1.89
Regular Market Open 1.83
Regular Market Previous Close 1.84
Regular Market Price 1.775
Regular Market Time 1,776,787,710
Regular Market Volume 232,571
Return On Assets -0.19346
Return On Equity -0.61165
Revenue Growth 0.061
Revenue Per Share 0.155
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 105,361,064
Shares Percent Shares Out 0.015800001
Shares Short 1,667,465
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 1,704,877
Short Name ProQR Therapeutics N.V.
Short Percent Of Float 0.0233
Short Ratio 4.24
Source Interval 15
Symbol PRQR
Target High Price 14.0
Target Low Price 4.0
Target Mean Price 8.875
Target Median Price 8.5
Total Cash 92,413,000
Total Cash Per Share 0.877
Total Debt 15,964,000
Total Revenue 16,347,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.47
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.047
Two Hundred Day Average Change -0.27199996
Two Hundred Day Average Change Percent -0.13287736
Type Disp Equity
Volume 232,571
Website https://www.proqr.com
Zip 2,333 CK