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Prelude Therapeutics Incorporated (PRLD)

Healthcare | Biotechnology | Wilmington, United States | NasdaqGS
4.44 USD +0.01 (0.226%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 4.50 +0.06 (1.351%) ⇧ (April 17, 2026, 6:19 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 1:19 p.m. EDT

PRLD appears to be a high-risk, low-reward opportunity with a volatile price history and lack of dividend payouts. While there are some positive developments in the news, such as FDA clearance and new research, the company's financials show significant losses and negative earnings. The short-term forecast suggests a slight downward trend, and the long-term outlook is uncertain. Investors should proceed with caution and consider the high risk associated with this stock.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.360687
AutoETS0.360755
AutoARIMA0.360761
MSTL0.398787

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 41%
H-stat 27.61
Ljung-Box p 0.000
Jarque-Bera p 0.571
Excess Kurtosis -0.77
Attribute Value
Sector Healthcare
Debt to Equity Ratio 25.918
Revenue per Share 0.158
Market Cap 279,121,824
Forward P/E -3.88
Beta 0.72
Website https://preludetx.com

As of April 11, 2026, 1:19 p.m. EDT: Options speculators are showing mixed signals. For calls, there is a significant amount of open interest (OI) and volume at the $5.0 strike, which is ATM, suggesting some bullish sentiment. However, the implied volatility (IV) is low, indicating limited expectations for large price movements. For puts, there is substantial OI and volume at the $2.5 strike, which is significantly below the current price, suggesting potential bearish sentiment or hedging against downside risk. The overall options activity does not provide a clear consensus on future price direction, but the presence of ATM anchors and OI at lower strikes indicates caution.


Info Dump

Attribute Value
52 Week Change 4.5569463
Address1 175 Innovation Boulevard
All Time High 95.375
All Time Low 0.61
Ask 5.29
Ask Size 2
Average Daily Volume10 Day 446,560
Average Daily Volume3 Month 310,435
Average Volume 310,435
Average Volume10Days 446,560
Beta 0.715
Bid 3.24
Bid Size 2
Book Value 0.832
City Wilmington
Compensation As Of Epoch Date 1,735,603,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 4.44
Current Ratio 1.994
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 4.5
Day Low 4.1001
Debt To Equity 25.918
Earnings Call Timestamp End 1,762,952,400
Earnings Call Timestamp Start 1,762,952,400
Earnings Timestamp 1,773,145,800
Earnings Timestamp End 1,778,675,400
Earnings Timestamp Start 1,778,675,400
Ebitda -101,555,000
Ebitda Margins 0.0
Enterprise To Ebitda -2.767
Enterprise To Revenue 23.149
Enterprise Value 281,027,904
Eps Current Year -1.11
Eps Forward -1.145
Eps Trailing Twelve Months -1.29
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.1959
Fifty Day Average Change 1.2441001
Fifty Day Average Change Percent 0.38928005
Fifty Two Week Change Percent 455.69464
Fifty Two Week High 5.54
Fifty Two Week High Change -1.0999999
Fifty Two Week High Change Percent -0.19855595
Fifty Two Week Low 0.73
Fifty Two Week Low Change 3.71
Fifty Two Week Low Change Percent 5.0821915
Fifty Two Week Range 0.73 - 5.54
Financial Currency USD
First Trade Date Milliseconds 1,601,040,600,000
Float Shares 14,559,075
Forward Eps -1.145
Forward P E -3.8777294
Free Cashflow -23,872,250
Full Exchange Name NasdaqGS
Full Time Employees 79
Gmt Off Set Milliseconds -14,400,000
Gross Margins 1.0
Gross Profits 12,140,000
Has Pre Post Market Data 1
Held Percent Insiders 0.105
Held Percent Institutions 0.59167
Implied Shares Outstanding 62,865,270
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,020-09-25
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.
Long Name Prelude Therapeutics Incorporated
Market us_market
Market Cap 279,121,824
Market State CLOSED
Max Age 86,400
Message Board Id finmb_373775974
Most Recent Quarter 1,767,139,200
Net Income To Common -99,498,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 280,143,643
Number Of Analyst Opinions 3
Open 4.5
Operating Cashflow -56,302,000
Operating Margins -2.84539
Payout Ratio 0.0
Phone 302 467 1280
Post Market Change 0.059999943
Post Market Change Percent 1.3513501
Post Market Price 4.5
Post Market Time 1,776,464,352
Previous Close 4.43
Price Eps Current Year -4.0
Price Hint 4
Price To Book 5.3365383
Price To Sales Trailing12 Months 22.991913
Profit Margins 0.0
Quick Ratio 1.948
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.0100002
Regular Market Change Percent 0.225739
Regular Market Day High 4.5
Regular Market Day Low 4.1001
Regular Market Day Range 4.1001 - 4.5
Regular Market Open 4.5
Regular Market Previous Close 4.43
Regular Market Price 4.44
Regular Market Time 1,776,456,000
Regular Market Volume 351,200
Return On Assets -0.40742
Return On Equity -0.9945
Revenue Growth 0.41
Revenue Per Share 0.158
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 43,765,011
Shares Percent Shares Out 0.0368
Shares Short 2,319,677
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 2,272,634
Short Name Prelude Therapeutics Incorporat
Short Percent Of Float 0.1934
Short Ratio 10.45
Source Interval 15
State DE
Symbol PRLD
Target High Price 6.0
Target Low Price 4.5
Target Mean Price 5.16667
Target Median Price 5.0
Total Cash 103,214,000
Total Cash Per Share 1.251
Total Debt 17,789,000
Total Revenue 12,140,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -1.29
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.910655
Two Hundred Day Average Change 2.529345
Two Hundred Day Average Change Percent 1.3238105
Type Disp Equity
Volume 351,200
Website https://preludetx.com
Zip 19,805