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ProMIS Neurosciences, Inc. (PMN)

Healthcare | Biotechnology | Toronto, Canada | NasdaqCM
12.80 USD -1.45 (-10.175%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 12.80

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:58 a.m. EDT

The immediate outlook is neutral-to-slightly-bearish due to a lack of clear directional edge, despite a recent price bounce off the lows. The stock has surged nearly 45% in the last two weeks, moving from roughly $10 to $14.25, which suggests some short-term momentum, but the underlying business fundamentals are severely compromised. The company is burning significant cash with negative operating and free cash flows, and the balance sheet is deteriorating rapidly. The most critical red flag is the multi-year price trajectory: the asset has lost over 94% of its value since 2016, with four consecutive years of negative annual returns ending in a massive 81.5% drop last year. This structural decline indicates that the market has permanently reassessed the business quality downward, rendering any 'value' narrative moot. Furthermore, there is no dividend income to offset the capital loss, and the company recently raised $175 million just to extend its runway, highlighting a desperate need for capital rather than sustainable profitability. While analysts project a 230% upside, this appears to be a speculative bet on a future catalyst rather than a reflection of current operational reality.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.055459
AutoETS0.055461
MSTL0.069271
AutoTheta0.266563

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 23%
H-stat 5.33
Ljung-Box p 0.000
Jarque-Bera p 0.000
Excess Kurtosis 3.56
Attribute Value
Sector Healthcare
Market Cap 114,786,472
Forward P/E -5.36
Beta -0.21
Website https://www.promisneurosciences.com

Info Dump

Attribute Value
52 Week Change 0.096153855
Address1 1,920 Yonge Street
Address2 Suite 200
All Time High 2,580.0
All Time Low 6.27
Ask 16.79
Ask Size 2
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 81,190
Average Daily Volume3 Month 36,877
Average Volume 36,877
Average Volume10Days 81,190
Beta -0.211
Bid 10.21
Bid Size 2
Book Value 6.771
City Toronto
Compensation As Of Epoch Date 1,767,139,200
Country Canada
Crypto Tradeable 0
Currency USD
Current Price 12.8
Current Ratio 9.919
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 14.7599
Day Low 12.8
Display Name ProMIS Neurosciences
Earnings Timestamp End 1,754,569,800
Earnings Timestamp Start 1,754,569,800
Ebitda Margins 0.0
Enterprise Value 50,938,372
Eps Current Year -8.241
Eps Forward -2.3876243
Eps Trailing Twelve Months -16.53
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 10.9662
Fifty Day Average Change 1.8338003
Fifty Day Average Change Percent 0.16722295
Fifty Two Week Change Percent 9.615385
Fifty Two Week High 39.75
Fifty Two Week High Change -26.95
Fifty Two Week High Change Percent -0.67798746
Fifty Two Week Low 6.27
Fifty Two Week Low Change 6.53
Fifty Two Week Low Change Percent 1.0414673
Fifty Two Week Range 6.27 - 39.75
Financial Currency USD
First Trade Date Milliseconds 1,168,439,400,000
Float Shares 4,597,467
Forward Eps -2.3876243
Forward P E -5.3609776
Free Cashflow -18,816,976
Full Exchange Name NasdaqCM
Full Time Employees 10
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Gross Profits -33,379,320
Has Pre Post Market Data 1
Held Percent Insiders 0.11846
Held Percent Institutions 0.74367
Implied Shares Outstanding 8,967,693
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,764,288,000
Last Split Factor 1:25
Long Business Summary ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS, which enables drug discovery through a combination of protein biology, physics, and supercomputing. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer's disease; PMN267 for the treatment of amyotrophic lateral sclerosis; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils for treating multiple system atrophy. The company also develops PNM440, an alpha-synuclein vaccine for treating multiple synucleinopathies; and PMN311, an amyloid-beta vaccine for the treatment of Alzheimer's. In addition, it is developing therapies for frontotemporal lobar degeneration, Huntington's disease, progressive supranuclear palsy, corticobasal degeneration, and schizophrenia. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. is headquartered in Toronto, Canada.
Long Name ProMIS Neurosciences, Inc.
Market us_market
Market Cap 114,786,472
Market State PREPRE
Max Age 86,400
Message Board Id finmb_11795000
Most Recent Quarter 1,774,915,200
Net Income To Common -40,615,616
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 114,786,470
Number Of Analyst Opinions 6
Open 14.11
Operating Cashflow -35,575,232
Operating Margins 0.0
Payout Ratio 0.0
Phone 416 847 6898
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 12.8
Post Market Time 1,783,973,404
Previous Close 14.25
Price Eps Current Year -1.5532095
Price Hint 2
Price To Book 1.8904151
Profit Margins 0.0
Quick Ratio 9.689
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.28571
Region US
Regular Market Change -1.45
Regular Market Change Percent -10.1754
Regular Market Day High 14.7599
Regular Market Day Low 12.8
Regular Market Day Range 12.8 - 14.7599
Regular Market Open 14.11
Regular Market Previous Close 14.25
Regular Market Price 12.8
Regular Market Time 1,783,972,800
Regular Market Volume 75,806
Return On Assets -0.62998
Return On Equity -1.15732
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 8,967,693
Shares Percent Shares Out 0.0227
Shares Short 203,926
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 188,790
Short Name ProMIS Neurosciences Inc.
Short Percent Of Float 0.0229
Short Ratio 6.67
Source Interval 15
State ON
Symbol PMN
Target High Price 48.19872
Target Low Price 18.11981
Target Mean Price 32.317303
Target Median Price 34.096596
Total Cash 63,848,096
Total Cash Per Share 7.12
Total Debt 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -16.53
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 11.83125
Two Hundred Day Average Change 0.96875
Two Hundred Day Average Change Percent 0.081880614
Type Disp Equity
Volume 75,806
Website https://www.promisneurosciences.com
Zip M4S 3E2