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Polaryx Therapeutics, Inc. (PLYX)

Healthcare | Biotechnology | Paramus, United States | NasdaqCM
2.06 USD -0.05 (-2.370%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 2.15 +0.09 (4.369%) ⇧ (Aug. 28, 2026, 7:45 p.m. EDT)

Short-term:★★⯪☆☆Long-term:⯪☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 4:15 a.m. EDT

The immediate outlook is neutral-to-slightly-bearish as the stock trades flat against its 50-day moving average, showing no clear momentum edge despite recent volatility. However, the long-term investment case is severely compromised; the company is a biotech firm with negative earnings, negative free cash flow, and a return on equity of nearly -97%, indicating a business that is burning capital without generating returns. The price action confirms this deterioration, as the stock has fallen approximately 58% over the trailing 200 days, suggesting the market has already priced in significant distress. Furthermore, there is no dividend history to provide any income cushion, making this a pure speculative play on a failing balance sheet rather than a viable investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.255484
AutoTheta0.266626
AutoETS0.329418
AutoARIMA0.709055

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 32%
H-stat 1.97
Ljung-Box p 0.000
Jarque-Bera p 0.956
Excess Kurtosis 0.12
Attribute Value
Sector Healthcare
Market Cap 97,527,184
Website https://polaryx.com

Info Dump

Attribute Value
52 Week Change -0.94114286
Address1 South Tower
Address2 140 E Ridgewood Avenue Suite 415
All Time High 48.91
All Time Low 1.85
Ask 2.59
Ask Size 2
Average Daily Volume10 Day 130,360
Average Daily Volume3 Month 127,020
Average Volume 127,020
Average Volume10Days 130,360
Bid 1.52
Bid Size 2
Book Value 0.219
City Paramus
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.06
Current Ratio 13.53
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 2.138
Day Low 1.97
Display Name Polaryx Therapeutics
Ebitda Margins 0.0
Enterprise Value 91,140,744
Eps Trailing Twelve Months -0.14
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.2726
Fifty Day Average Change -0.2126
Fifty Day Average Change Percent -0.09354924
Fifty Two Week Change Percent -94.11429
Fifty Two Week High 48.91
Fifty Two Week High Change -46.85
Fifty Two Week High Change Percent -0.9578818
Fifty Two Week Low 1.85
Fifty Two Week Low Change 0.20999992
Fifty Two Week Low Change Percent 0.11351347
Fifty Two Week Range 1.85 - 48.91
Financial Currency USD
First Trade Date Milliseconds 1,770,042,600,000
Float Shares 6,777,560
Free Cashflow -2,086,375
Full Exchange Name NasdaqCM
Full Time Employees 2
Fullday Change -0.05
Fullday Change Percent -2.36967
Fullday Price 2.15
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.69921994
Held Percent Institutions 0.04401
Implied Shares Outstanding 47,343,297
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,026-02-02
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Polaryx Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of disease-modifying therapies for rare and pediatric lysosomal storage disorders in the United States. Its pipeline includes PLX-100, a preclinical stage orally administrable combination therapy; PLX-200, a repurposed oral small molecule for the treatment of LSDs; PLX-300, a preclinical stage orally administrable combination therapy; and PLX-400, a preclinical stage novel gene therapy candidate. The company was founded in 2014 and is based in Paramus, New Jersey.
Long Name Polaryx Therapeutics, Inc.
Market us_market
Market Cap 97,527,184
Market State CLOSED
Max Age 86,400
Message Board Id finmb_414729746
Most Recent Quarter 1,782,777,600
Net Income To Common -6,849,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 104,178,125
Number Of Analyst Opinions 4
Open 2.09
Operating Cashflow -5,809,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 201 940 7236
Post Market Change 0.09000015
Post Market Change Percent 4.3689394
Post Market Price 2.15
Post Market Time 1,787,960,721
Previous Close 2.11
Price Hint 4
Price To Book 9.406392
Profit Margins 0.0
Quick Ratio 13.221
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.05
Regular Market Change Percent -2.36967
Regular Market Day High 2.138
Regular Market Day Low 1.97
Regular Market Day Range 1.97 - 2.138
Regular Market Open 2.09
Regular Market Previous Close 2.11
Regular Market Price 2.06
Regular Market Time 1,787,947,201
Regular Market Volume 85,848
Return On Assets -0.42519
Return On Equity -0.96559995
Sand P52 Week Change 0.20204377
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 47,343,297
Shares Percent Shares Out 0.005
Shares Short 249,038
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 306,529
Short Name Polaryx Therapeutics, Inc.
Short Percent Of Float 0.0115
Short Ratio 2.51
Source Interval 15
State NJ
Symbol PLYX
Target High Price 10.0
Target Low Price 6.0
Target Mean Price 7.5
Target Median Price 7.0
Total Cash 11,542,000
Total Cash Per Share 0.232
Total Debt 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.14
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 4.153931
Two Hundred Day Average Change -2.0939312
Two Hundred Day Average Change Percent -0.5040842
Type Disp Equity
Volume 85,848
Website https://polaryx.com
Zip 7,652