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Protalix BioTherapeutics, Inc. (PLX)

Healthcare | Biotechnology | Hackensack, United States | NYSE American
2.39 USD -0.05 (-2.049%) ⇩ (July 13, 2026, 4 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★★☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 4:21 a.m. EDT

The investment case here is a study in contrasts between explosive recent growth and a precarious historical trajectory. Fundamentally, the company is firing on all cylinders with 234% revenue growth in the latest quarter, robust operating margins above 60%, and a return on equity nearing 27%. The balance sheet is surprisingly healthy for a biotech, carrying minimal debt against substantial cash reserves. However, the long-term price history tells a different story; despite the recent recovery, the stock has been down nearly 78% over the last nine years, reflecting a long struggle to prove its commercial thesis. The current price action shows a slight upward lean, trading above its 50-day moving average, which aligns with the improving fundamentals. Yet, the statistical forecast models remain neutral, capturing the uncertainty inherent in the sector. With no dividend to provide income, the entire return proposition relies on the continued execution of its pipeline and the eventual resolution of the long-term valuation discount. It is a high-risk, high-reward speculative play on a turnaround story that has finally found its footing.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.052452
AutoETS0.053228
MSTL0.053712
AutoTheta0.096104

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 42%
H-stat 0.68
Ljung-Box p 0.000
Jarque-Bera p 0.218
Excess Kurtosis -0.60
Attribute Value
Sector Healthcare
Debt to Equity Ratio 12.615
Revenue per Share 0.963
Market Cap 192,566,224
Trailing P/E 12.58
Forward P/E 3.85
Beta 0.00
Profit Margins 20.07%
Website https://www.protalix.com

As of July 11, 2026, 4:21 a.m. EDT: Speculators are positioning for significant volatility rather than a specific directional move. There is heavy open interest in out-of-the-money calls at the $5.0 strike across multiple expirations, suggesting a speculative bet on a massive upside event or binary outcome. Conversely, put writers are accumulating significant protection at the $2.0 strike, creating a floor around current prices. The implied volatility is elevated on both sides, indicating the market expects a wide range of outcomes.


Info Dump

Attribute Value
52 Week Change 0.7183099
Address1 2 University Plaza
Address2 Suite 100
All Time High 912.5
All Time Low 0.7
Ask 2.38
Ask Size 2,200
Audit Risk 8
Average Daily Volume10 Day 732,360
Average Daily Volume3 Month 728,877
Average Volume 728,877
Average Volume10Days 732,360
Beta -0.002
Bid 0.0
Bid Size 1,600
Board Risk 7
Book Value 0.834
City Hackensack
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 8
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.39
Current Ratio 3.153
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 2.48
Day Low 2.39
Debt To Equity 12.615
Display Name Protalix BioTherapeutics
Dividend Date 1,576,800,000
Earnings Call Timestamp End 1,778,673,600
Earnings Call Timestamp Start 1,778,673,600
Earnings Timestamp 1,778,675,400
Earnings Timestamp End 1,786,624,200
Earnings Timestamp Start 1,786,624,200
Ebitda 21,314,000
Ebitda Margins 0.27905
Enterprise To Ebitda 7.036
Enterprise To Revenue 1.963
Enterprise Value 149,964,224
Eps Forward 0.62
Eps Trailing Twelve Months 0.19
Esg Populated 0
Exchange ASE
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.1052
Fifty Day Average Change 0.28480005
Fifty Day Average Change Percent 0.13528408
Fifty Two Week Change Percent 71.830986
Fifty Two Week High 3.19
Fifty Two Week High Change -0.79999995
Fifty Two Week High Change Percent -0.25078368
Fifty Two Week Low 1.36
Fifty Two Week Low Change 1.0300001
Fifty Two Week Low Change Percent 0.757353
Fifty Two Week Range 1.36 - 3.19
Financial Currency USD
First Trade Date Milliseconds 895,239,000,000
Float Shares 77,447,074
Forward Eps 0.62
Forward P E 3.8548388
Free Cashflow 6,783,125
Full Exchange Name NYSE American
Full Time Employees 226
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.45236
Gross Profits 34,552,000
Has Pre Post Market Data 1
Held Percent Insiders 0.03878
Held Percent Institutions 0.21326
Implied Shares Outstanding 80,571,642
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,576,800,000
Last Split Factor 1:10
Long Business Summary Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company provides Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial for the treatment of gout; and PRX-119, a plant cell expressed PEGylated recombinant human DNase I product candidate for the treatment of neutrophil extracellular traps diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. Protalix BioTherapeutics, Inc. has strategic partnership with Secarna Pharmaceuticals GmbH & Co KG. The company is headquartered in Hackensack. New Jersey.
Long Name Protalix BioTherapeutics, Inc.
Market us_market
Market Cap 192,566,224
Market State PRE
Max Age 86,400
Message Board Id finmb_941520
Most Recent Quarter 1,774,915,200
Net Income To Common 15,332,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 196,594,806
Number Of Analyst Opinions 2
Open 2.45
Operating Cashflow 15,090,000
Operating Margins 0.62654996
Overall Risk 6
Payout Ratio 0.0
Phone 201 696 9345
Previous Close 2.44
Price Hint 4
Price To Book 2.8657076
Price To Sales Trailing12 Months 2.5211272
Profit Margins 0.20073
Quick Ratio 1.972
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.05
Regular Market Change Percent -2.04918
Regular Market Day High 2.48
Regular Market Day Low 2.39
Regular Market Day Range 2.39 - 2.48
Regular Market Open 2.45
Regular Market Previous Close 2.44
Regular Market Price 2.39
Regular Market Time 1,783,972,800
Regular Market Volume 485,476
Return On Assets 0.14038
Return On Equity 0.27271998
Revenue Growth 2.337
Revenue Per Share 0.963
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 80,571,642
Shares Percent Shares Out 0.0442
Shares Short 3,558,923
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 3,935,161
Short Name Protalix BioTherapeutics, Inc.
Short Percent Of Float 0.046
Short Ratio 5.12
Source Interval 15
State NJ
Symbol PLX
Target High Price 12.0
Target Low Price 10.0
Target Mean Price 11.0
Target Median Price 11.0
Total Cash 51,083,000
Total Cash Per Share 0.634
Total Debt 8,481,000
Total Revenue 76,381,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 0.19
Trailing P E 12.578948
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.21245
Two Hundred Day Average Change 0.17755008
Two Hundred Day Average Change Percent 0.080250435
Type Disp Equity
Volume 485,476
Website https://www.protalix.com
Zip 7,601