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Protalix BioTherapeutics, Inc. (PLX)

Healthcare | Biotechnology | Hackensack, United States | NYSE American
2.32 USD +0.02 (0.870%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 2.34 +0.02 (0.862%) ⇧ (April 17, 2026, 7:55 p.m. EDT)

Short-term: ★★★☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:34 p.m. EDT

Despite the recent 2.0 strike put wall acting as a hard floor, the slide is structural, not a temporary shock; fundamental deterioration (significant revenue drop, negative operating cash flow) combined with a negative model prediction suggests the long-term bullish thesis is currently on life support. The stock has failed to capitalize on the put-heavy short-term positioning, and a 3.62M share stake increase by a promoter appears insufficient to reverse the bleeding fundamentals or the -0.46% predicted directional drift.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.188534
AutoETS0.210650
MSTL0.210904
AutoTheta0.253336

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 53%
H-stat 3.11
Ljung-Box p 0.000
Jarque-Bera p 0.087
Excess Kurtosis -1.38
Attribute Value
Sector Healthcare
Debt to Equity Ratio 17.253
Revenue per Share 0.672
Market Cap 186,926,192
Forward P/E 3.74
Beta -0.09
Profit Margins -12.52%
Website https://www.protalix.com

As of April 18, 2026, 10:34 p.m. EDT: Options flow signals a distinct divergence between short-term hedging and long-term bullish positioning. Near-term expirations (April/May) show heavy Put Open Interest (OI) at the 2.0 strike, creating a 'floor' support zone, alongside a lack of Call OI. Conversely, longer-dated leases (August/November) see significant Call OI at the 5.0 and 7.5 strikes, with minimal Put OI beyond the 2.5 level. Implied Volatility is elevated (~2.5x) for near-term 2.0 strikes but compressed for further out dates, suggesting traders anticipate a choppy recovery or consolidation above 2.0 but view the upside potential to 5.0 as a non-event in the near term, stymied by current fundamentals.


Info Dump

Attribute Value
52 Week Change -0.09019607
Address1 2 University Plaza
Address2 Suite 100
All Time High 912.5
All Time Low 0.7
Ask 2.36
Ask Size 1,900
Audit Risk 7
Average Daily Volume10 Day 644,250
Average Daily Volume3 Month 1,235,751
Average Volume 1,235,751
Average Volume10Days 644,250
Beta -0.091
Bid 2.3
Bid Size 2,300
Board Risk 7
Book Value 0.6
City Hackensack
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.32
Current Ratio 2.514
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 2.34
Day Low 2.295
Debt To Equity 17.253
Display Name Protalix BioTherapeutics
Dividend Date 1,576,800,000
Earnings Call Timestamp End 1,773,835,200
Earnings Call Timestamp Start 1,773,835,200
Earnings Timestamp 1,773,837,000
Earnings Timestamp End 1,778,243,400
Earnings Timestamp Start 1,778,243,400
Ebitda -4,035,000
Ebitda Margins -0.0765
Enterprise To Ebitda -40.886
Enterprise To Revenue 3.128
Enterprise Value 164,974,208
Eps Forward 0.62
Eps Trailing Twelve Months -0.08
Esg Populated 0
Exchange ASE
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 2.5998
Fifty Day Average Change -0.27980018
Fifty Day Average Change Percent -0.107623726
Fifty Two Week Change Percent -9.019608
Fifty Two Week High 3.19
Fifty Two Week High Change -0.8700001
Fifty Two Week High Change Percent -0.2727273
Fifty Two Week Low 1.32
Fifty Two Week Low Change 0.9999999
Fifty Two Week Low Change Percent 0.75757563
Fifty Two Week Range 1.32 - 3.19
Financial Currency USD
First Trade Date Milliseconds 895,239,000,000
Float Shares 72,076,168
Forward Eps 0.62
Forward P E 3.7419353
Free Cashflow -12,196,875
Full Exchange Name NYSE American
Full Time Employees 226
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.1301
Gross Profits 6,862,000
Has Pre Post Market Data 1
Held Percent Insiders 0.10135
Held Percent Institutions 0.23813
Implied Shares Outstanding 80,571,642
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,576,800,000
Last Split Factor 1:10
Long Business Summary Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company provides Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial for the treatment of gout; and PRX-119, a plant cell expressed PEGylated recombinant human DNase I product candidate for the treatment of neutrophil extracellular traps diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. Protalix BioTherapeutics, Inc. has strategic partnership with Secarna Pharmaceuticals GmbH & Co KG. The company is headquartered in Hackensack. New Jersey.
Long Name Protalix BioTherapeutics, Inc.
Market us_market
Market Cap 186,926,192
Market State CLOSED
Max Age 86,400
Message Board Id finmb_941520
Most Recent Quarter 1,767,139,200
Net Income To Common -6,604,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 186,926,209
Number Of Analyst Opinions 2
Open 2.35
Operating Cashflow -11,993,000
Operating Margins -0.51063
Overall Risk 6
Payout Ratio 0.0
Phone 201 696 9345
Post Market Change 0.01999998
Post Market Change Percent 0.8620682
Post Market Price 2.34
Post Market Time 1,776,470,107
Previous Close 2.3
Price Hint 4
Price To Book 3.8666663
Price To Sales Trailing12 Months 3.5440276
Profit Margins -0.12521
Quick Ratio 1.499
Quote Source Name Delayed Quote
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.02
Regular Market Change Percent 0.869564
Regular Market Day High 2.34
Regular Market Day Low 2.295
Regular Market Day Range 2.295 - 2.34
Regular Market Open 2.35
Regular Market Previous Close 2.3
Regular Market Price 2.32
Regular Market Time 1,776,456,000
Regular Market Volume 536,469
Return On Assets -0.04414
Return On Equity -0.14444
Revenue Growth -0.499
Revenue Per Share 0.672
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 80,571,642
Shares Percent Shares Out 0.0584
Shares Short 4,702,042
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 4,174,736
Short Name Protalix BioTherapeutics, Inc.
Short Percent Of Float 0.060900003
Short Ratio 4.55
Source Interval 15
State NJ
Symbol PLX
Target High Price 12.0
Target Low Price 10.0
Target Mean Price 11.0
Target Median Price 11.0
Total Cash 30,273,000
Total Cash Per Share 0.376
Total Debt 8,321,000
Total Revenue 52,744,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.08
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.06095
Two Hundred Day Average Change 0.2590499
Two Hundred Day Average Change Percent 0.12569441
Type Disp Equity
Volume 536,469
Website https://www.protalix.com
Zip 7,601