Pliant Therapeutics, Inc. (PLRX)Healthcare | Biotechnology | South San Francisco, United States | NasdaqGS
1.28 USD
-0.01
(-1.163%) ⇩
(April 21, 2026, 3:22 p.m.
EDT)
Short-term: ★★☆☆☆ | Long-term: ★★☆☆☆ | Dividends: ☆☆☆☆☆ |
Hot Take | April 18, 2026, 11:46 p.m. EDT
Pliant Therapeutics remains a high-risk speculative hold with no dividend support and deteriorating technicals, currently trading below its key moving averages despite a slight 1-week rebound. The recent board restructuring and option repricing to the current price floor suggest insider alignment with the bottom, but the absence of institutional accumulation in options (IV ~1%) and negative analyst forecasts (-1.6% predicted) point to a continued grind lower unless a specific catalyst triggers a liquidity event or pricing recovery. |
| Model | MAE |
|---|---|
| MSTL ✓ | 0.043799 |
| AutoETS | 0.044381 |
| AutoARIMA | 0.044586 |
| AutoTheta | 0.113921 |
Forecast horizon: 45 days | Selected: MSTL
| Forecast Reliability | |
|---|---|
| Score | 80% |
| H-stat | 0.25 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.207 |
| Excess Kurtosis | -0.07 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 16.062 |
| Market Cap | 78,941,192 |
| Forward P/E | -1.05 |
| Beta | 1.25 |
| Website | https://pliantrx.com |
As of April 18, 2026, 11:46 p.m. EDT: Options flow shows absolute volume is extremely low across all expirations, with implied volatility near zero (0.50 - 1.66), indicating a lack of active speculation or liquidity at current lows. Positioning is sporadic and does not exhibit a clear directional bias; the 'Top OI' at the 7.5 strike for Oct 16 calls suggests detached, long-term speculative positioning by a single entity rather than market-wide conviction. Conversely, the 0.5 strike put on Oct 16 shows new flow but no open interest accumulation, suggesting transient activity. The data reflects a stale, low-volume environment where prices have continued to decline from the ATR (1.95) to current levels (1.33) without significant support at these lows.
| Attribute | Value |
|---|---|
| 52 Week Change | -0.13999999 |
| Address1 | 331 Oyster Point Boulevard |
| All Time High | 43.92 |
| All Time Low | 1.09 |
| Ask | 1.63 |
| Ask Size | 2 |
| Average Daily Volume10 Day | 512,680 |
| Average Daily Volume3 Month | 674,708 |
| Average Volume | 674,708 |
| Average Volume10Days | 512,680 |
| Beta | 1.245 |
| Bid | 0.9216 |
| Bid Size | 2 |
| Book Value | 2.949 |
| City | South San Francisco |
| Compensation As Of Epoch Date | 1,735,603,200 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 1.275 |
| Current Ratio | 12.004 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,774,915,200 |
| Day High | 1.31 |
| Day Low | 1.26 |
| Debt To Equity | 16.062 |
| Display Name | Pliant Therapeutics |
| Earnings Timestamp | 1,773,259,200 |
| Earnings Timestamp End | 1,778,184,000 |
| Earnings Timestamp Start | 1,778,184,000 |
| Ebitda | -148,376,992 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | 0.552 |
| Enterprise Value | -81,969,080 |
| Eps Current Year | -1.53445 |
| Eps Forward | -1.21718 |
| Eps Trailing Twelve Months | -2.43 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 1.2749 |
| Fifty Day Average Change | 0.000100016594 |
| Fifty Day Average Change Percent | 0.00007845055 |
| Fifty Two Week Change Percent | -13.999998 |
| Fifty Two Week High | 1.95 |
| Fifty Two Week High Change | -0.6750001 |
| Fifty Two Week High Change Percent | -0.3461539 |
| Fifty Two Week Low | 1.09 |
| Fifty Two Week Low Change | 0.18499994 |
| Fifty Two Week Low Change Percent | 0.16972472 |
| Fifty Two Week Range | 1.09 - 1.95 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,591,191,000,000 |
| Float Shares | 60,225,013 |
| Forward Eps | -1.21718 |
| Forward P E | -1.0475032 |
| Free Cashflow | -84,559,000 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 49 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Gross Margins | 0.0 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.02379 |
| Held Percent Institutions | 0.77718 |
| Implied Shares Outstanding | 61,914,664 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,020-06-03 |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company's lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of avß8 and avß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California. |
| Long Name | Pliant Therapeutics, Inc. |
| Market | us_market |
| Market Cap | 78,941,192 |
| Market State | REGULAR |
| Max Age | 86,400 |
| Message Board Id | finmb_325980525 |
| Most Recent Quarter | 1,767,139,200 |
| Net Income To Common | -149,344,000 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 79,250,769 |
| Number Of Analyst Opinions | 3 |
| Open | 1.28 |
| Operating Cashflow | -128,336,000 |
| Operating Margins | 0.0 |
| Payout Ratio | 0.0 |
| Phone | 650 481 6770 |
| Previous Close | 1.29 |
| Price Eps Current Year | -0.8309166 |
| Price Hint | 4 |
| Price To Book | 0.43234995 |
| Profit Margins | 0.0 |
| Quick Ratio | 11.718 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.014999986 |
| Regular Market Change Percent | -1.1627896 |
| Regular Market Day High | 1.31 |
| Regular Market Day Low | 1.26 |
| Regular Market Day Range | 1.26 - 1.31 |
| Regular Market Open | 1.28 |
| Regular Market Previous Close | 1.29 |
| Regular Market Price | 1.275 |
| Regular Market Time | 1,776,799,351 |
| Regular Market Volume | 609,873 |
| Return On Assets | -0.30150998 |
| Return On Equity | -0.61549 |
| Sand P52 Week Change | 0.34445214 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Shares Outstanding | 61,914,664 |
| Shares Percent Shares Out | 0.065 |
| Shares Short | 4,025,957 |
| Shares Short Previous Month Date | 1,772,150,400 |
| Shares Short Prior Month | 3,785,164 |
| Short Name | Pliant Therapeutics, Inc. |
| Short Percent Of Float | 0.066599995 |
| Short Ratio | 7.56 |
| Source Interval | 15 |
| State | CA |
| Symbol | PLRX |
| Target High Price | 3.0 |
| Target Low Price | 2.0 |
| Target Mean Price | 2.66667 |
| Target Median Price | 3.0 |
| Total Cash | 190,944,000 |
| Total Cash Per Share | 3.084 |
| Total Debt | 29,105,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -2.43 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.427575 |
| Two Hundred Day Average Change | -0.15257502 |
| Two Hundred Day Average Change Percent | -0.10687706 |
| Type Disp | Equity |
| Volume | 609,873 |
| Website | https://pliantrx.com |
| Zip | 94,080 |