| Browse All

Puma Biotechnology, Inc. (PBYI)

Healthcare | Biotechnology | Los Angeles, United States | NasdaqGS
7.37 USD +7.37 (-1.339%) ⇧ (April 20, 2026, 4 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 10:43 p.m. EDT

Despite bearish analyst consensus (all targets at $5.00) and negative forecast model predictions, the options flow is aggressively bullish, positioning capital for a move to $10.00 within weeks. The disconnect between the technical divergence (crossing above the 200-day MA) and the buy-side positioning at higher strikes suggests a speculative 'momentum play' is underway, betting on a re-acceleration of growth given the 27% revenue growth and improving profitability.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.067573
AutoETS0.067979
AutoTheta0.110767
AutoARIMA0.167058

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 54%
H-stat 2.84
Ljung-Box p 0.000
Jarque-Bera p 0.231
Excess Kurtosis -1.02
Attribute Value
Sector Healthcare
Debt to Equity Ratio 21.901
Revenue per Share 4.566
Market Cap 374,959,712
Trailing P/E 12.08
Forward P/E 11.34
Beta 1.18
Profit Margins 13.62%
Website https://www.pumabiotechnology.com

As of April 18, 2026, 10:43 p.m. EDT: Options market exhibits a strong bullish skew. Call Open Interest (OI) is heavily concentrated out-of-the-money at the $10.00 strike for most expirations, with the largest volume and OI placed there for the May contract. The $7.50 strike serves as a high-volume anchor across all call tenors. Conversely, put activity is minimal and distant, with low OI at strikes significantly below current price (e.g., $2.50 - $5.00), indicating a lack of hedging interest or downside positioning. Implied volatility for deep OTM calls (10.0) is elevated compared to ATM calls, suggesting speculators are pricing in a higher probability of upside movement or a significant gap to the upside.


Info Dump

Attribute Value
52 Week Change 1.4485049
Address1 10,880 Wilshire Boulevard
Address2 Suite 1700
All Time High 279.37
All Time Low 1.6
Ask 7.42
Ask Size 1
Audit Risk 6
Average Daily Volume10 Day 307,950
Average Daily Volume3 Month 393,201
Average Volume 393,201
Average Volume10Days 307,950
Beta 1.177
Bid 7.34
Bid Size 1
Board Risk 6
Book Value 2.586
City Los Angeles
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 7.37
Current Ratio 2.002
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 7.5
Day Low 7.32
Debt To Equity 21.901
Display Name Puma Biotechnology
Earnings Call Timestamp End 1,772,141,400
Earnings Call Timestamp Start 1,772,141,400
Earnings Growth -0.344
Earnings Quarterly Growth -0.304
Earnings Timestamp 1,772,139,600
Earnings Timestamp End 1,778,529,600
Earnings Timestamp Start 1,778,529,600
Ebitda 47,437,000
Ebitda Margins 0.20772
Enterprise To Ebitda 6.45
Enterprise To Revenue 1.34
Enterprise Value 305,977,696
Eps Current Year 0.4
Eps Forward 0.65
Eps Trailing Twelve Months 0.61
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.6838
Fifty Day Average Change 0.68619967
Fifty Day Average Change Percent 0.102666095
Fifty Two Week Change Percent 144.8505
Fifty Two Week High 7.9
Fifty Two Week High Change -0.5300002
Fifty Two Week High Change Percent -0.067088634
Fifty Two Week Low 2.85
Fifty Two Week Low Change 4.52
Fifty Two Week Low Change Percent 1.5859649
Fifty Two Week Range 2.85 - 7.9
Financial Currency USD
First Trade Date Milliseconds 1,335,274,200,000
Float Shares 39,005,985
Forward Eps 0.65
Forward P E 11.338462
Free Cashflow 30,693,124
Full Exchange Name NasdaqGS
Full Time Employees 179
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.74534
Gross Profits 170,214,000
Has Pre Post Market Data 1
Held Percent Insiders 0.15635
Held Percent Institutions 0.72644997
Implied Shares Outstanding 50,876,487
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. It sells its products through specialty pharmacy and distributor networks. The company has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. Puma Biotechnology, Inc. was founded in 2010 and is headquartered in Los Angeles, California.
Long Name Puma Biotechnology, Inc.
Market us_market
Market Cap 374,959,712
Market State PRE
Max Age 86,400
Message Board Id finmb_128739842
Most Recent Quarter 1,767,139,200
Net Income To Common 31,111,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 380,301,740
Number Of Analyst Opinions 1
Open 7.45
Operating Cashflow 41,802,000
Operating Margins 0.22670999
Overall Risk 4
Payout Ratio 0.0
Phone 424 248 6500
Previous Close 0.0
Price Eps Current Year 18.425
Price Hint 2
Price To Book 2.8499613
Price To Sales Trailing12 Months 1.6418884
Profit Margins 0.13623
Quick Ratio 1.861
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 7.37
Regular Market Change Percent -1.33869
Regular Market Day High 7.5
Regular Market Day Low 7.32
Regular Market Day Range 7.32 - 7.5
Regular Market Open 7.45
Regular Market Previous Close 0.0
Regular Market Price 7.37
Regular Market Time 1,776,715,200
Regular Market Volume 213,992
Return On Assets 0.10852
Return On Equity 0.27969
Revenue Growth 0.277
Revenue Per Share 4.566
Sand P52 Week Change 0.34445214
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 50,876,487
Shares Percent Shares Out 0.0774
Shares Short 3,936,887
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 3,764,191
Short Name Puma Biotechnology Inc
Short Percent Of Float 0.090299994
Short Ratio 11.43
Source Interval 15
State CA
Symbol PBYI
Target High Price 5.0
Target Low Price 5.0
Target Mean Price 5.0
Target Median Price 5.0
Total Cash 97,528,000
Total Cash Per Share 1.917
Total Debt 28,546,000
Total Revenue 228,371,008
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield NaN
Trailing Eps 0.61
Trailing P E 12.081966
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 5.4639
Two Hundred Day Average Change 1.9060998
Two Hundred Day Average Change Percent 0.34885335
Type Disp Equity
Volume 213,992
Website https://www.pumabiotechnology.com
Zip 90,024