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Palisade Bio, Inc. (PALI)

Healthcare | Biotechnology | Denver, United States | NasdaqCM
2.40 USD +0.07 (3.004%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 2.38 -0.02 (-0.019%) ⇩ (April 17, 2026, 7:54 p.m. EDT)

Short-term: ★★★★☆ | Long-term: ★★★☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 18, 2026, 6:06 p.m. EDT

PALI represents a high-volatility, binary event play driven by speculative analyst optimism and recent positive Phase 1b data, rather than fundamental profitability. While the stock is currently exhibiting strong upward momentum with a significant 30%+ rally off its 50-day average, the negative earnings trajectory, cash burn, and recent equity dilution ($3M raise) create a classic speculative biotech setup. The forecasting model indicates a mild bullish bias (approx. 6.7%) but is heavily compromised by extreme serial correlation (Ljung-Box p-value near zero), suggesting the current price action is trending mechanically rather than efficiently, making this a precarious short-term momentum trade with significant downside risk if clinical data fails to meet inflated expectations.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoETS ✓0.072338
MSTL0.073144
AutoTheta0.073373
AutoARIMA0.088125

Forecast horizon: 45 days | Selected: AutoETS

Forecast Reliability
Score 80%
H-stat 0.14
Ljung-Box p 0.000
Jarque-Bera p 0.372
Excess Kurtosis -0.90
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.055
Market Cap 402,292,096
Forward P/E -8.57
Beta 1.47
Previous Name Seneca Biopharma, Inc.
Website https://www.palisadebio.com

Info Dump

Attribute Value
52 Week Change 2.3802817
Address1 4,600 South Syracuse Street
Address2 Suite 900
All Time High 5,627,700.0
All Time Low 0.53
Ask 2.41
Ask Size 1
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 3,580,900
Average Daily Volume3 Month 3,956,788
Average Volume 3,956,788
Average Volume10Days 3,580,900
Beta 1.47
Bid 1.75
Bid Size 2
Book Value 0.811
City Denver
Compensation As Of Epoch Date 1,735,603,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 2.4
Current Ratio 28.952
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 2.45
Day Low 2.275
Debt To Equity 0.055
Display Name Palisade Bio
Dividend Date 1,563,408,000
Earnings Timestamp End 1,755,288,000
Earnings Timestamp Start 1,754,942,400
Ebitda -18,053,000
Ebitda Margins 0.0
Enterprise To Ebitda -14.669
Enterprise Value 264,811,568
Eps Current Year -0.192
Eps Forward -0.28
Eps Trailing Twelve Months -0.3
Esg Populated 0
Exchange NCM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.8622
Fifty Day Average Change 0.5378001
Fifty Day Average Change Percent 0.28879824
Fifty Two Week Change Percent 238.02817
Fifty Two Week High 2.64
Fifty Two Week High Change -0.24000001
Fifty Two Week High Change Percent -0.09090909
Fifty Two Week Low 0.53
Fifty Two Week Low Change 1.8700001
Fifty Two Week Low Change Percent 3.5283022
Fifty Two Week Range 0.53 - 2.64
Financial Currency USD
First Trade Date Milliseconds 1,175,261,400,000
Float Shares 122,671,822
Forward Eps -0.28
Forward P E -8.571429
Free Cashflow -5,923,250
Full Exchange Name NasdaqCM
Full Time Employees 14
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.00028
Held Percent Institutions 0.81703
Implied Shares Outstanding 167,621,702
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,712,534,400
Last Split Factor 1:15
Long Business Summary Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn's disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and commercialization of its compounds; license agreement with the Regents of the University of California for sole purpose of maintaining the Newsoara Co-Development; and a co-development and distribution agreement with Newsoara Biopharma Co., Ltd. The company was founded in 2001 and is headquartered in Denver, Colorado.
Long Name Palisade Bio, Inc.
Market us_market
Market Cap 402,292,096
Market State CLOSED
Max Age 86,400
Message Board Id finmb_244367385
Most Recent Quarter 1,767,139,200
Name Change Date 2,026-04-19
Net Income To Common -16,781,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 402,292,084
Number Of Analyst Opinions 8
Open 2.35
Operating Cashflow -10,847,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 858 704 4900
Post Market Change -0.01910019
Post Market Change Percent -0.79584116
Post Market Price 2.3809
Post Market Time 1,776,470,052
Prev Name Seneca Biopharma, Inc.
Previous Close 2.33
Price Eps Current Year -12.5
Price Hint 4
Price To Book 2.9593096
Profit Margins 0.0
Quick Ratio 28.829
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.25
Region US
Regular Market Change 0.0700002
Regular Market Change Percent 3.0043
Regular Market Day High 2.45
Regular Market Day Low 2.275
Regular Market Day Range 2.275 - 2.45
Regular Market Open 2.35
Regular Market Previous Close 2.33
Regular Market Price 2.4
Regular Market Time 1,776,456,000
Regular Market Volume 3,533,940
Return On Assets -0.15542
Return On Equity -0.24520999
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 167,421,702
Shares Percent Shares Out 0.1537
Shares Short 25,770,313
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 26,733,844
Short Name Palisade Bio, Inc.
Short Percent Of Float 0.1539
Short Ratio 6.5
Source Interval 15
State CO
Symbol PALI
Target High Price 25.0
Target Low Price 5.0
Target Mean Price 11.125
Target Median Price 7.5
Total Cash 133,385,000
Total Cash Per Share 0.804
Total Debt 71,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.3
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.53815
Two Hundred Day Average Change 0.86185014
Two Hundred Day Average Change Percent 0.5603161
Type Disp Equity
Volume 3,533,940
Website https://www.palisadebio.com
Zip 80,237