| Indicators | Browse All

Pacific Biosciences of California, Inc. (PACB)

Healthcare | Medical Devices | Menlo Park, United States | NasdaqGS
1.50 USD 0.00 (-0.080%) ⇩ (July 15, 2026, 12:25 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 5:21 a.m. EDT

The long-term investment case is severely compromised by deteriorating fundamentals and a brutal multi-year price trajectory. Despite the company's innovative sequencing technology, the financial reality is stark: the business is burning cash with negative operating margins, a massive debt load relative to equity, and a return on equity that is deeply negative. The price history confirms the market's rejection of the current business model, showing an 80% cumulative decline over the last nine years and two consecutive years of falling prices. This is not a value trap; it is a structural decline where the market has correctly priced out the lack of sustainable profitability and growth. In the short term, the stock remains a speculative gamble. While the price has recently bounced off lows, the technical setup is fragile, trading below key moving averages with high beta volatility amplifying the risk. The options market reflects this uncertainty, with traders buying protection against further drops rather than betting on a recovery. With no dividend to provide income and a balance sheet that requires constant capital raising to survive, the risk/reward profile is skewed heavily toward the downside. Investors should view this as a high-risk speculative vehicle rather than an investment opportunity.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.124798
AutoTheta0.130466
AutoETS0.130537
AutoARIMA0.130538

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 40%
H-stat 0.15
Ljung-Box p 0.000
Jarque-Bera p 0.335
Excess Kurtosis -1.07
Attribute Value
Sector Healthcare
Debt to Equity Ratio 29855.79
Revenue per Share 0.53
Market Cap 465,529,824
Forward P/E -3.78
Beta 2.29
Profit Margins -80.34%
Website https://www.pacb.com

As of July 11, 2026, 5:21 a.m. EDT: Speculators are positioning defensively with heavy put volume relative to calls, particularly in the January 2027 expiration where out-of-the-money puts show significant open interest. Implied volatility is elevated on the downside side compared to the upside, suggesting a fear of further decline rather than a bullish breakout. The ATM anchor strikes see mixed flow, but the concentration of open interest at lower strikes indicates a 'floor' mentality among traders.


Info Dump

Attribute Value
52 Week Change 0.006711364
Address1 1,305 O’Brien Drive
All Time High 53.69
All Time Low 0.85
Ask 1.92
Ask Size 2
Audit Risk 6
Average Daily Volume10 Day 4,992,050
Average Daily Volume3 Month 6,255,521
Average Volume 6,255,521
Average Volume10Days 4,992,050
Beta 2.289
Bid 1.08
Bid Size 2
Board Risk 3
Book Value 0.008
City Menlo Park
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 10
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.4988
Current Ratio 5.654
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 1.535
Day Low 1.48
Debt To Equity 29,855.79
Display Name Pacific Biosciences of California
Earnings Call Timestamp End 1,778,185,800
Earnings Call Timestamp Start 1,778,185,800
Earnings Timestamp 1,778,184,000
Earnings Timestamp End 1,786,046,400
Earnings Timestamp Start 1,786,046,400
Ebitda -143,146,000
Ebitda Margins -0.89449
Enterprise To Ebitda -6.262
Enterprise To Revenue 5.601
Enterprise Value 896,328,512
Eps Current Year -0.5064
Eps Forward -0.3966
Eps Trailing Twelve Months -0.41
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fax 650 618 2699
Fifty Day Average 1.445
Fifty Day Average Change 0.053799987
Fifty Day Average Change Percent 0.037231825
Fifty Two Week Change Percent 0.6711364
Fifty Two Week High 2.73
Fifty Two Week High Change -1.2312
Fifty Two Week High Change Percent -0.450989
Fifty Two Week Low 1.09
Fifty Two Week Low Change 0.4088
Fifty Two Week Low Change Percent 0.37504587
Fifty Two Week Range 1.09 - 2.73
Financial Currency USD
First Trade Date Milliseconds 1,288,186,200,000
Float Shares 303,830,571
Forward Eps -0.3966
Forward P E -3.7791226
Free Cashflow -48,237,124
Full Exchange Name NasdaqGS
Full Time Employees 485
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.38327
Gross Profits 61,334,000
Has Pre Post Market Data 1
Held Percent Insiders 0.08768
Held Percent Institutions 0.53812003
Implied Shares Outstanding 310,601,688
Industry Medical Devices
Industry Disp Medical Devices
Industry Key medical-devices
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems. The company provides sequencing systems; consumable products, including single molecule real-time (SMRT) technology; long-read sequencing; and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. In addition, the company provides Revio, Vega, and Sequel instruments which conduct, monitor, and analyze single-molecule biochemical reactions on SMRT cell microchips; short-read sequencing; and onso instrument. It serves academic and governmental research institutions, commercial testing and service laboratories, genome centers, public health labs, hospitals and clinical research institutes, contract research organizations, pharmaceutical companies, and agricultural companies. The company markets its products through a sales force and distribution partners in Australia, certain parts of Asia, Europe, the Middle East, Africa, Central America, and South America. It has a collaboration with DNAstack Inc. to provide federated dataset of HiFi whole genome sequencing data. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.
Long Name Pacific Biosciences of California, Inc.
Market us_market
Market Cap 465,529,824
Market State REGULAR
Max Age 86,400
Message Board Id finmb_11461617
Most Recent Quarter 1,774,915,200
Net Income To Common -128,576,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 467,455,540
Number Of Analyst Opinions 6
Open 1.51
Operating Cashflow -111,844,000
Operating Margins -1.02891
Overall Risk 7
Payout Ratio 0.0
Phone 650 521 8000
Previous Close 1.5
Price Eps Current Year -2.9597158
Price Hint 4
Price To Book 187.34999
Price To Sales Trailing12 Months 2.909016
Profit Margins -0.80345
Quick Ratio 4.672
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change -0.0011999607
Regular Market Change Percent -0.07999738
Regular Market Day High 1.535
Regular Market Day Low 1.48
Regular Market Day Range 1.48 - 1.535
Regular Market Open 1.51
Regular Market Previous Close 1.5
Regular Market Price 1.4988
Regular Market Time 1,784,132,747
Regular Market Volume 1,734,167
Return On Assets -0.11965
Return On Equity -2.73554
Revenue Growth 0.001
Revenue Per Share 0.53
Sand P52 Week Change 0.2043345
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 310,601,688
Shares Percent Shares Out 0.1529
Shares Short 47,490,204
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 48,707,384
Short Name Pacific Biosciences of Californ
Short Percent Of Float 0.1758
Short Ratio 7.15
Source Interval 15
State CA
Symbol PACB
Target High Price 3.0
Target Low Price 1.5
Target Mean Price 2.45833
Target Median Price 2.625
Total Cash 275,961,984
Total Cash Per Share 0.888
Total Debt 706,387,968
Total Revenue 160,030,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.41
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.70755
Two Hundred Day Average Change -0.20875001
Two Hundred Day Average Change Percent -0.12225118
Type Disp Equity
Volume 1,734,167
Website https://www.pacb.com
Zip 94,025