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Oruka Therapeutics, Inc. (ORKA)

Healthcare | Biotechnology | Menlo Park, United States | NasdaqGM
80.35 USD -1.76 (-2.143%) ⇩ (Oct. 12, 2026, 4 p.m. EDT)
Short-term:★★☆☆☆Long-term:★★★☆☆Dividends:★☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 4:09 a.m. EDT

The balance sheet is a fortress, with nearly $873 million in cash against negligible debt, providing ample runway for development. However, the stock has erased 95% of its value over the past nine years, and recent price action shows weakness trading below the 50-day moving average despite positive analyst upgrades. While the cash position supports a long-term hold, the lack of profitability and the steep historical decline suggest caution until clinical catalysts materialize. The options market is pricing in a binary event, betting on either a recovery to $120 or a defense near $75.
Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.098298
AutoETS0.102661
AutoTheta0.230707
AutoARIMA0.340602

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 39%
H-stat 4.26
Ljung-Box p 0.000
Jarque-Bera p 0.419
Excess Kurtosis -0.93
Attribute Value
Sector Healthcare
Last Dividend Date 2024-08-28
Debt to Equity Ratio 0.228
Market Cap 5,319,949,312
Forward P/E -28.07
Beta -0.11
Website https://orukatx.com

As of Oct. 10, 2026, 4:09 a.m. EDT: Speculators are positioning for volatility with elevated implied volatility across expirations. Call buyers are targeting upside to $105 and $120 for 2027, while put sellers are defending the $75 level for late 2026. The heavy open interest at out-of-the-money strikes suggests a belief in a binary outcome rather than steady appreciation.

Dividend Data

Dividend History
Date Dividend Yield %
2024-08-29 19.356 64.52
Additional Data
dividendYield 0.0
trailingAnnualDividendRate 0.0
trailingAnnualDividendYield 0.0
lastDividendValue 19.356
lastDividendDate 2024-08-29
dividendDate 2024-08-28

Info Dump

Attribute Value
52 Week Change 1.9239447
Address1 855 Oak Grove Avenue
Address2 Suite 100
All Time High 75,932,640.0
All Time Low 5.49
Ask 126.45
Ask Size 2
Audit Risk 6
Average Analyst Rating 1.2 - Strong Buy
Average Daily Volume10 Day 994,250
Average Daily Volume3 Month 904,118
Average Volume 904,118
Average Volume10Days 994,250
Beta -0.106
Bid 71.53
Bid Size 2
Board Risk 5
Book Value 18.202
City Menlo Park
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 80.35
Current Ratio 38.513
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 82.95
Day Low 79.43
Debt To Equity 0.228
Display Name Oruka Therapeutics
Dividend Date 1,724,803,200
Dividend Yield 0.0
Earnings Timestamp 1,786,365,000
Earnings Timestamp End 1,794,400,200
Earnings Timestamp Start 1,794,400,200
Ebitda -154,943,008
Ebitda Margins 0.0
Enterprise To Ebitda -28.732
Enterprise Value 4,451,862,528
Eps Current Year -2.36632
Eps Forward -2.86212
Eps Trailing Twelve Months -2.04
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 94.332
Fifty Day Average Change -13.982002
Fifty Day Average Change Percent -0.1482212
Fifty Two Week Change Percent 192.39447
Fifty Two Week High 115.52
Fifty Two Week High Change -35.17
Fifty Two Week High Change Percent -0.30444944
Fifty Two Week Low 24.88
Fifty Two Week Low Change 55.47
Fifty Two Week Low Change Percent 2.2295017
Fifty Two Week Range 24.88 - 115.52
Financial Currency USD
First Trade Date Milliseconds 871,047,000,000
Float Shares 56,890,684
Forward Eps -2.86212
Forward P E -28.073597
Free Cashflow -65,032,124
Full Exchange Name NasdaqGM
Full Time Employees 68
Fullday Change -1.7600021
Fullday Change Percent -2.1434686
Fullday Price 80.35
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,790,812,800
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.012569999
Held Percent Institutions 1.16599
Implied Shares Outstanding 66,209,699
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ir Website http://phx.corporate-ir.net/phoenix.zhtml?c=109749&p=irol-irhome
Is Earnings Date Estimate 1
Language en-US
Last Dividend Date 1,724,889,600
Last Dividend Value 19.356
Last Fiscal Year End 1,767,139,200
Last Split Date 1,725,321,600
Last Split Factor 1:12
Long Business Summary Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an undisclosed pathway; and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001. Oruka Therapeutics, Inc. is headquartered in Menlo Park, California.
Long Name Oruka Therapeutics, Inc.
Market us_market
Market Cap 5,319,949,312
Market State PRE
Max Age 86,400
Message Board Id finmb_1877171755
Most Recent Quarter 1,782,777,600
Net Income To Common -109,688,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 5,953,907,182
Number Of Analyst Opinions 12
Open 81.81
Operating Cashflow -100,919,000
Operating Margins 0.0
Overall Risk 8
Phone 650 606 7910
Previous Close 82.11
Price Eps Current Year -33.955677
Price Hint 2
Price To Book 4.41435
Profit Margins 0.0
Quick Ratio 38.034
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.15385
Region US
Regular Market Change -1.76
Regular Market Change Percent -2.14347
Regular Market Day High 82.95
Regular Market Day Low 79.43
Regular Market Day Range 79.43 - 82.95
Regular Market Open 81.81
Regular Market Previous Close 82.11
Regular Market Price 80.35
Regular Market Time 1,791,835,200
Regular Market Volume 547,917
Return On Assets -0.12951
Return On Equity -0.18225999
Sand P52 Week Change 0.17318833
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 8
Shares Outstanding 66,209,699
Shares Percent Shares Out 0.1175
Shares Short 7,778,131
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 7,793,678
Short Name Oruka Therapeutics, Inc.
Short Percent Of Float 0.171
Short Ratio 7.87
Source Interval 15
State CA
Symbol ORKA
Target High Price 200.0
Target Low Price 117.0
Target Mean Price 155.0
Target Median Price 155.5
Total Cash 873,564,032
Total Cash Per Share 13.194
Total Debt 2,546,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -2.04
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 65.43745
Two Hundred Day Average Change 14.912552
Two Hundred Day Average Change Percent 0.2278902
Type Disp Equity
Volume 547,917
Website https://orukatx.com
Zip 94,025