OPKO Health, Inc. (OPK)Healthcare | Diagnostics & Research | Miami, United States | NasdaqGS
1.23 USD
-0.12
(-8.889%) ⇩
(July 13, 2026, 4 p.m.
EDT)
After hours: 1.25 +0.02 (1.626%) ⇧ (July 13, 2026, 6:40 p.m. EDT) |
Hot Take ↕ | July 11, 2026, 3:15 a.m. EDT
The long-term outlook is dire, driven by a brutal nine-year price trajectory where the stock has lost over 86% of its value. The most damning evidence is the relentless five-year streak of negative annual returns, which signals a structural failure in the business model rather than a temporary setback. Fundamentals confirm this decay: revenue is shrinking by 17%, operating margins are deeply negative at -41%, and the company is burning cash with no free cash flow to speak of. The balance sheet is fragile, with debt significantly outweighing equity, and there is no dividend to provide any cushion for shareholders. In the short term, the picture remains bleak despite a minor technical bounce off the lows. The stock is trading below its book value, but this is a value trap, not a bargain, given the deteriorating earnings power. Options activity reinforces this bearish sentiment; the market is heavily hedged against further drops, with massive put open interest acting as a ceiling for rallies. While the statistical forecast model shows a weak lean downward, it is too noisy to offer actionable insight compared to the overwhelming fundamental rot. Investors should view this as a high-risk speculative vehicle with no clear path to recovery, warranting avoidance. |
| Model | MAE |
|---|---|
| MSTL_105 ✓ | 0.099581 |
| MSTL_52_105 | 0.112023 |
| AutoARIMA | 0.131622 |
| AutoETS | 0.131622 |
| MSTL | 0.132011 |
| MSTL_52 | 0.139564 |
| AutoTheta | 0.142635 |
Forecast horizon: 60 days | Selected: MSTL_105
| Forecast Reliability | |
|---|---|
| Score | 38% |
| H-stat | 5.64 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.161 |
| Excess Kurtosis | -0.92 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 32.951 |
| Revenue per Share | 0.752 |
| Market Cap | 928,763,456 |
| Forward P/E | -3.84 |
| Beta | 1.48 |
| Profit Margins | -36.64% |
| Website | https://www.opko.com |
As of July 11, 2026, 3:15 a.m. EDT: Speculators are overwhelmingly positioned for downside protection rather than upside speculation. Put open interest dominates across nearly all expirations, particularly in the deep out-of-the-money strikes (below $1.00) and the ATM strike ($1.50), creating a dense 'wall' of downside insurance. Call activity is sparse and concentrated at lower strikes, suggesting traders are betting on a continued grind lower or a bounce to the $1.00 floor, while the heavy put positioning indicates a fear of further deterioration in the underlying business.
| Attribute | Value |
|---|---|
| 52 Week Change | 0.00746274 |
| Address1 | 4,400 Biscayne Boulevard |
| All Time High | 19.2 |
| All Time Low | 0.21 |
| Ask | 1.23 |
| Ask Size | 1 |
| Audit Risk | 3 |
| Average Daily Volume10 Day | 3,270,280 |
| Average Daily Volume3 Month | 2,703,932 |
| Average Volume | 2,703,932 |
| Average Volume10Days | 3,270,280 |
| Beta | 1.478 |
| Bid | 1.04 |
| Bid Size | 1 |
| Board Risk | 10 |
| Book Value | 1.595 |
| City | Miami |
| Compensation As Of Epoch Date | 1,767,139,200 |
| Compensation Risk | 6 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 1.23 |
| Current Ratio | 3.608 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,782,777,600 |
| Day High | 1.35 |
| Day Low | 1.22 |
| Debt To Equity | 32.951 |
| Display Name | OPKO Health |
| Earnings Call Timestamp End | 1,777,408,200 |
| Earnings Call Timestamp Start | 1,777,408,200 |
| Earnings Timestamp | 1,777,406,400 |
| Earnings Timestamp End | 1,777,406,400 |
| Earnings Timestamp Start | 1,777,406,400 |
| Ebitda | -112,493,000 |
| Ebitda Margins | -0.19358 |
| Enterprise To Ebitda | -8.835 |
| Enterprise To Revenue | 1.71 |
| Enterprise Value | 993,828,480 |
| Eps Current Year | -0.38 |
| Eps Forward | -0.32 |
| Eps Trailing Twelve Months | -0.27 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 1.3322 |
| Fifty Day Average Change | -0.10220003 |
| Fifty Day Average Change Percent | -0.07671523 |
| Fifty Two Week Change Percent | 0.746274 |
| Fifty Two Week High | 1.61 |
| Fifty Two Week High Change | -0.38 |
| Fifty Two Week High Change Percent | -0.23602484 |
| Fifty Two Week Low | 0.98 |
| Fifty Two Week Low Change | 0.25 |
| Fifty Two Week Low Change Percent | 0.25510204 |
| Fifty Two Week Range | 0.98 - 1.61 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 815,322,600,000 |
| Float Shares | 332,822,014 |
| Forward Eps | -0.32 |
| Forward P E | -3.8437502 |
| Free Cashflow | -36,094,624 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 2,275 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,782,864,000 |
| Gross Margins | 0.14917 |
| Gross Profits | 86,684,000 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.49949002 |
| Held Percent Institutions | 0.27008 |
| Implied Shares Outstanding | 755,092,256 |
| Industry | Diagnostics & Research |
| Industry Disp | Diagnostics & Research |
| Industry Key | diagnostics-research |
| Ir Website | http://investor.opko.com/ |
| Is Earnings Date Estimate | 0 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida. |
| Long Name | OPKO Health, Inc. |
| Market | us_market |
| Market Cap | 928,763,456 |
| Market State | PREPRE |
| Max Age | 86,400 |
| Message Board Id | finmb_33405327 |
| Most Recent Quarter | 1,774,915,200 |
| Net Income To Common | -212,915,008 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,019,374,545 |
| Number Of Analyst Opinions | 4 |
| Open | 1.34 |
| Operating Cashflow | -163,298,000 |
| Operating Margins | -0.41077998 |
| Overall Risk | 7 |
| Payout Ratio | 0.0 |
| Peg Ratio | 93.65 |
| Phone | 305 575 4100 |
| Post Market Change | 0.01999998 |
| Post Market Change Percent | 1.6260147 |
| Post Market Price | 1.25 |
| Post Market Time | 1,783,982,417 |
| Previous Close | 1.35 |
| Price Eps Current Year | -3.2368422 |
| Price Hint | 4 |
| Price To Book | 0.7711599 |
| Price To Sales Trailing12 Months | 1.5982218 |
| Profit Margins | -0.36639 |
| Quick Ratio | 2.83 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.12 |
| Regular Market Change Percent | -8.88889 |
| Regular Market Day High | 1.35 |
| Regular Market Day Low | 1.22 |
| Regular Market Day Range | 1.22 - 1.35 |
| Regular Market Open | 1.34 |
| Regular Market Previous Close | 1.35 |
| Regular Market Price | 1.23 |
| Regular Market Time | 1,783,972,800 |
| Regular Market Volume | 5,060,363 |
| Return On Assets | -0.06362 |
| Return On Equity | -0.16923 |
| Revenue Growth | -0.172 |
| Revenue Per Share | 0.752 |
| Sand P52 Week Change | 0.20847368 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 3 |
| Shares Outstanding | 755,092,256 |
| Shares Percent Shares Out | 0.0432 |
| Shares Short | 32,594,765 |
| Shares Short Previous Month Date | 1,780,012,800 |
| Shares Short Prior Month | 33,037,706 |
| Short Name | Opko Health, Inc. |
| Short Percent Of Float | 0.077 |
| Short Ratio | 10.16 |
| Source Interval | 15 |
| State | FL |
| Symbol | OPK |
| Target High Price | 8.5 |
| Target Low Price | 3.0 |
| Target Mean Price | 4.375 |
| Target Median Price | 3.0 |
| Total Cash | 331,862,016 |
| Total Cash Per Share | 0.439 |
| Total Debt | 396,927,008 |
| Total Revenue | 581,123,008 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -0.27 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 1.3111 |
| Two Hundred Day Average Change | -0.08109999 |
| Two Hundred Day Average Change Percent | -0.061856445 |
| Type Disp | Equity |
| Volume | 5,060,363 |
| Website | https://www.opko.com |
| Zip | 33,137 |