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OPKO Health, Inc. (OPK)

Healthcare | Diagnostics & Research | Miami, United States | NasdaqGS
1.24 USD +0.03 (2.479%) ⇧ (April 17, 2026, 3:41 p.m. EDT)

Short-term: ★★☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 11, 2026, 2:46 p.m. EDT

OPKO Health (OPK) is currently in a volatile and uncertain environment, with a negative fundamental outlook and weak earnings. The recent price action has been volatile, with a significant dip to its 52-week low, which may indicate a buying opportunity for short-term traders. However, the long-term fundamentals are weak, with negative profit margins and a high debt-to-equity ratio, making it a risky investment for long-term holders. The lack of dividends and the overall negative sentiment in the market suggest that investors should be cautious. The options activity indicates a mix of bullish and bearish sentiment, with a potential for short-term volatility, but the overall outlook remains negative.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.076552
AutoETS0.079776
MSTL0.087128
AutoARIMA0.105645

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 53%
H-stat 3.10
Ljung-Box p 0.000
Jarque-Bera p 0.852
Excess Kurtosis -0.20
Attribute Value
Sector Healthcare
Debt to Equity Ratio 31.293
Revenue per Share 0.808
Market Cap 951,949,632
Forward P/E -3.76
Beta 1.49
Profit Margins -37.19%
Website https://www.opko.com

As of April 11, 2026, 2:46 p.m. EDT: The options data indicates a mix of short-term and long-term speculation. Calls are heavily positioned at the 1.5 strike, suggesting some bullish sentiment, although the implied volatility is low. Puts show higher interest at the 1.5 strike, indicating potential bearishness or hedging. The overall options activity suggests uncertainty, with a tendency towards short-term volatility. The high open interest in puts at the 1.5 strike may imply that traders are preparing for a potential decline, while the calls at the same strike suggest some optimism. The low IV and high OI in puts suggest a cautious outlook, possibly due to the recent dip and negative fundamentals.


Info Dump

Attribute Value
52 Week Change -0.11678833
Address1 4,400 Biscayne Boulevard
All Time High 19.2
All Time Low 0.21
Ask 1.41
Ask Size 1
Audit Risk 6
Average Analyst Rating 2.0 - Buy
Average Daily Volume10 Day 2,154,290
Average Daily Volume3 Month 2,706,601
Average Volume 2,706,601
Average Volume10Days 2,154,290
Beta 1.491
Bid 1.05
Bid Size 1
Board Risk 10
Book Value 1.67
City Miami
Compensation As Of Epoch Date 1,735,603,200
Compensation Risk 6
Country United States
Crypto Tradeable 0
Currency USD
Current Price 1.24
Current Ratio 3.967
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 1.25
Day Low 1.21
Debt To Equity 31.293
Display Name OPKO Health
Earnings Call Timestamp End 1,772,141,400
Earnings Call Timestamp Start 1,772,141,400
Earnings Timestamp 1,772,139,600
Earnings Timestamp End 1,777,579,200
Earnings Timestamp Start 1,777,579,200
Ebitda -127,358,000
Ebitda Margins -0.20986
Enterprise To Ebitda -7.466
Enterprise To Revenue 1.567
Enterprise Value 950,844,352
Eps Current Year -0.34
Eps Forward -0.33
Eps Trailing Twelve Months -0.3
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 1.1836
Fifty Day Average Change 0.05640006
Fifty Day Average Change Percent 0.047651287
Fifty Two Week Change Percent -11.678833
Fifty Two Week High 1.6
Fifty Two Week High Change -0.36
Fifty Two Week High Change Percent -0.22500001
Fifty Two Week Low 1.1
Fifty Two Week Low Change 0.13999999
Fifty Two Week Low Change Percent 0.12727271
Fifty Two Week Range 1.1 - 1.6
Financial Currency USD
First Trade Date Milliseconds 815,322,600,000
Float Shares 336,297,157
Forward Eps -0.33
Forward P E -3.7575758
Free Cashflow -131,252,376
Full Exchange Name NasdaqGS
Full Time Employees 2,275
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,775,001,600
Gross Margins 0.13496
Gross Profits 81,907,000
Has Pre Post Market Data 1
Held Percent Insiders 0.49345002
Held Percent Institutions 0.27021
Implied Shares Outstanding 767,701,281
Industry Diagnostics & Research
Industry Disp Diagnostics & Research
Industry Key diagnostics-research
Ir Website http://investor.opko.com/
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.
Long Name OPKO Health, Inc.
Market us_market
Market Cap 951,949,632
Market State REGULAR
Max Age 86,400
Message Board Id finmb_33405327
Most Recent Quarter 1,767,139,200
Net Income To Common -225,680,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 922,266,716
Number Of Analyst Opinions 6
Open 1.23
Operating Cashflow -178,542,000
Operating Margins -0.28977
Overall Risk 7
Payout Ratio 0.0
Peg Ratio 93.6471
Phone 305 575 4100
Previous Close 1.21
Price Eps Current Year -3.6470587
Price Hint 4
Price To Book 0.74251497
Price To Sales Trailing12 Months 1.5685987
Profit Margins -0.37187
Quick Ratio 3.212
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key buy
Recommendation Mean 2.0
Region US
Regular Market Change 0.029999971
Regular Market Change Percent 2.4793365
Regular Market Day High 1.25
Regular Market Day Low 1.21
Regular Market Day Range 1.21 - 1.25
Regular Market Open 1.23
Regular Market Previous Close 1.21
Regular Market Price 1.24
Regular Market Time 1,776,454,870
Regular Market Volume 1,155,201
Return On Assets -0.06624
Return On Equity -0.1714
Revenue Growth -0.192
Revenue Per Share 0.808
Sand P52 Week Change 0.36506534
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 3
Shares Outstanding 759,067,256
Shares Percent Shares Out 0.044299997
Shares Short 33,615,361
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 31,374,396
Short Name Opko Health, Inc.
Short Percent Of Float 0.0779
Short Ratio 12.74
Source Interval 15
State FL
Symbol OPK
Target High Price 8.5
Target Low Price 1.4
Target Mean Price 3.4
Target Median Price 3.0
Total Cash 364,408,992
Total Cash Per Share 0.48
Total Debt 396,782,016
Total Revenue 606,878,976
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.3
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 1.3246
Two Hundred Day Average Change -0.08459997
Two Hundred Day Average Change Percent -0.063868314
Type Disp Equity
Volume 1,155,201
Website https://www.opko.com
Zip 33,137