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BeOne Medicines AG (ONC)

Healthcare | Biotechnology | Basel, Switzerland | NasdaqGS
366.73 USD -5.76 (-1.546%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 366.73

Short-term:★★★★☆Long-term:★★★★⯪Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 2:14 a.m. EDT

BeOne Medicines presents a compelling long-term investment case anchored by exceptional growth metrics and a fortress balance sheet. The company is delivering nearly 30% revenue growth and 166% earnings expansion, supported by a net cash position and strong free cash flow. Over the last nine years, the stock has delivered a nearly 10x return with no structural decline in the trailing trajectory, validating the market's premium valuation. Analysts maintain a strong buy consensus with a target price significantly above current levels. In the short term, momentum is building as the stock trades near its 52-week high, driven by recent positive clinical data presentations. Options flow confirms this bullish sentiment with aggressive call positioning at higher strikes, though the statistical forecast model remains neutral, suggesting potential short-term noise. The absence of a dividend means investors rely entirely on capital appreciation. While the valuation is steep, the underlying business quality and cash generation justify the premium for a patient holder, making this a high-conviction entry for long-term portfolios despite the elevated entry point.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.163397
MSTL0.174320
AutoETS0.179269
AutoARIMA0.183885

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 39%
H-stat 8.49
Ljung-Box p 0.000
Jarque-Bera p 0.271
Excess Kurtosis -1.14
Attribute Value
Sector Healthcare
Debt to Equity Ratio 39.612
Revenue per Share 55.275
Market Cap 41,485,291,520
Trailing P/E 66.68
Forward P/E 35.66
Beta 0.50
Profit Margins 10.70%
Previous Name BeiGene, Ltd.
Website https://beonemedicines.com

As of Aug. 22, 2026, 2:14 a.m. EDT: Speculators are positioning for upside with significant call open interest at $400 and $430 strikes for November 2026, while maintaining substantial put protection at $310 and $330 for September and November expirations. Implied volatility remains elevated around 40-45%, reflecting anticipation of upcoming clinical data or regulatory milestones.


Info Dump

Attribute Value
52 Week Change 0.121822715
Address1 94 Aeschengraben 27
All Time High 426.56
All Time Low 22.51
Ask 366.88
Ask Size 1
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 350,470
Average Daily Volume3 Month 360,948
Average Volume 360,948
Average Volume10Days 350,470
Beta 0.5
Bid 346.74
Bid Size 1
Book Value 45.779
City Basel
Compensation As Of Epoch Date 1,767,139,200
Country Switzerland
Crypto Tradeable 0
Currency USD
Current Price 366.73
Current Ratio 3.405
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 372.0
Day Low 364.75
Debt To Equity 39.612
Display Name BeOne Medicines
Earnings Call Timestamp End 1,785,931,200
Earnings Call Timestamp Start 1,785,931,200
Earnings Growth 1.667
Earnings Quarterly Growth 1.513
Earnings Timestamp 1,785,933,000
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda 1,071,609,024
Ebitda Margins 0.17483999
Enterprise To Ebitda 36.067
Enterprise To Revenue 6.306
Enterprise Value 38,649,372,672
Eps Current Year 7.59764
Eps Forward 10.2839
Eps Trailing Twelve Months 5.5
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 322.9002
Fifty Day Average Change 43.829803
Fifty Day Average Change Percent 0.13573793
Fifty Two Week Change Percent 12.182272
Fifty Two Week High 385.22
Fifty Two Week High Change -18.48999
Fifty Two Week High Change Percent -0.04799852
Fifty Two Week Low 253.948
Fifty Two Week Low Change 112.78201
Fifty Two Week Low Change Percent 0.4441146
Fifty Two Week Range 253.948 - 385.22
Financial Currency USD
First Trade Date Milliseconds 1,454,509,800,000
Float Shares 80,952,326
Forward Eps 10.2839
Forward P E 35.660595
Free Cashflow 879,021,888
Full Exchange Name NasdaqGS
Full Time Employees 12,000
Fullday Change -5.75998
Fullday Change Percent -1.54634
Fullday Price 366.73
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.88894
Gross Profits 5,448,286,208
Has Pre Post Market Data 1
Held Percent Insiders 0.17277001
Held Percent Institutions 0.3312
Implied Shares Outstanding 113,122,161
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.
Long Name BeOne Medicines AG
Market us_market
Market Cap 41,485,291,520
Market State CLOSED
Max Age 86,400
Message Board Id finmb_115205344
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-08-28
Net Income To Common 655,707,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 43,866,798,220
Number Of Analyst Opinions 28
Open 369.13
Operating Cashflow 1,484,056,064
Operating Margins 0.19063999
Payout Ratio 0.0
Peg Ratio 1.07
Phone 41 61 685 19 00
Post Market Change 0.0
Post Market Change Percent 0.0
Post Market Price 366.73
Post Market Time 1,787,959,805
Prev Name BeiGene, Ltd.
Previous Close 372.49
Price Eps Current Year 48.268936
Price Hint 2
Price To Book 8.010879
Price To Sales Trailing12 Months 6.768729
Profit Margins 0.106979996
Quick Ratio 2.911
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.32143
Region US
Regular Market Change -5.75998
Regular Market Change Percent -1.54634
Regular Market Day High 372.0
Regular Market Day Low 364.75
Regular Market Day Range 364.75 - 372.0
Regular Market Open 369.13
Regular Market Previous Close 372.49
Regular Market Price 366.73
Regular Market Time 1,787,947,200
Regular Market Volume 295,938
Return On Assets 0.07457
Return On Equity 0.14661999
Revenue Growth 0.296
Revenue Per Share 55.275
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 104,271,757
Shares Percent Shares Out 0.0113
Shares Short 1,276,075
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 926,986
Short Name BeOne Medicines Ltd.
Short Percent Of Float 0.0159
Short Ratio 2.98
Source Interval 15
Symbol ONC
Target High Price 528.0
Target Low Price 370.0
Target Mean Price 432.1582
Target Median Price 427.5
Total Cash 5,098,040,832
Total Cash Per Share 44.837
Total Debt 2,049,524,992
Total Revenue 6,128,963,072
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 5.5
Trailing P E 66.678185
Trailing Peg Ratio 1.0616
Triggerable 1
Two Hundred Day Average 317.8738
Two Hundred Day Average Change 48.8562
Two Hundred Day Average Change Percent 0.15369685
Type Disp Equity
Volume 295,938
Website https://beonemedicines.com
Zip 4,051