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BeOne Medicines AG (ONC)

Healthcare | Biotechnology | Basel, Switzerland | NasdaqGS
353.09 USD +4.01 (1.148%) ⇧ (Oct. 14, 2026, 11:33 a.m. EDT)

Short-term:★★★⯪☆Long-term:★★★★☆Dividends:☆☆☆☆☆
Hot Take ↕ | Oct. 10, 2026, 3:47 a.m. EDT

BeOne Medicines offers a rare combination of explosive growth and financial stability in the biotech space. The company has demonstrated remarkable resilience, recovering from a severe 2022 downturn to deliver a nearly 900% cumulative gain over the last nine years. Revenue is expanding at nearly 30% annually, backed by a fortress balance sheet with net cash reserves and healthy margins. While the valuation is premium, the analyst consensus and growth trajectory justify the cost for a long-term portfolio. However, the stock is currently trading slightly below its 50-day moving average, and short-term statistical models hint at minor downside pressure. Investors should view this as a core long-term hold with exceptional growth credentials, while respecting the technical resistance near the 50-day average for shorter-term entries.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
MSTL ✓0.099809
AutoTheta0.101439
AutoETS0.108561
AutoARIMA0.108563

Forecast horizon: 45 days | Selected: MSTL

Forecast Reliability
Score 46%
H-stat 8.49
Ljung-Box p 0.000
Jarque-Bera p 0.183
Excess Kurtosis -1.04
Attribute Value
Sector Healthcare
Debt to Equity Ratio 39.612
Revenue per Share 55.275
Market Cap 40,170,516,480
Trailing P/E 63.16
Forward P/E 34.44
Beta 0.61
Profit Margins 10.70%
Previous Name BeiGene, Ltd.
Website https://beonemedicines.com

As of Oct. 10, 2026, 3:47 a.m. EDT: Implied volatility remains elevated in the 40-50% range, pricing in significant price swings. Call open interest skews heavily out-of-the-money across November and February expirations, with notable concentration at strikes above 390, signaling speculative bets on substantial upside. Put open interest clusters near the money, suggesting institutional hedging rather than pure bearish conviction. Unusual volume spikes at specific strikes indicate active positioning on both sides.


Info Dump

Attribute Value
52 Week Change 0.104159474
Address1 94 Aeschengraben 27
All Time High 426.56
All Time Low 22.51
Ask 358.96
Ask Size 1
Average Analyst Rating 1.3 - Strong Buy
Average Daily Volume10 Day 332,980
Average Daily Volume3 Month 388,700
Average Volume 388,700
Average Volume10Days 332,980
Beta 0.609
Bid 250.0
Bid Size 4
Book Value 45.779
City Basel
Compensation As Of Epoch Date 1,767,139,200
Country Switzerland
Crypto Tradeable 0
Currency USD
Current Price 353.09
Current Ratio 3.405
Custom Price Alert Confidence HIGH
Date Short Interest 1,790,726,400
Day High 354.39
Day Low 345.84
Debt To Equity 39.612
Display Name BeOne Medicines
Dividend Yield 0.0
Earnings Call Timestamp End 1,785,931,200
Earnings Call Timestamp Start 1,785,931,200
Earnings Growth 1.667
Earnings Quarterly Growth 1.513
Earnings Timestamp 1,785,933,000
Earnings Timestamp End 1,793,881,800
Earnings Timestamp Start 1,793,881,800
Ebitda 1,071,609,024
Ebitda Margins 0.17483999
Enterprise To Ebitda 34.194
Enterprise To Revenue 5.979
Enterprise Value 36,642,537,472
Eps Current Year 7.64144
Eps Forward 10.25178
Eps Trailing Twelve Months 5.59
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 15
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 357.9309
Fifty Day Average Change -4.840912
Fifty Day Average Change Percent -0.01352471
Fifty Two Week Change Percent 10.415947
Fifty Two Week High 385.22
Fifty Two Week High Change -32.130005
Fifty Two Week High Change Percent -0.083406895
Fifty Two Week Low 253.948
Fifty Two Week Low Change 99.142
Fifty Two Week Low Change Percent 0.39040276
Fifty Two Week Range 253.948 - 385.22
Financial Currency USD
First Trade Date Milliseconds 1,454,509,800,000
Float Shares 80,959,148
Forward Eps 10.25178
Forward P E 34.441826
Free Cashflow 879,021,888
Full Exchange Name NasdaqGS
Full Time Employees 12,000
Fullday Change 4.01001
Fullday Change Percent 1.1480788
Fullday Price 353.09
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.88894
Gross Profits 5,448,286,208
Has Pre Post Market Data 1
Held Percent Insiders 0.17277001
Held Percent Institutions 0.33280998
Implied Shares Outstanding 113,768,498
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. The company has a agreement with U.S. government to expand access to innovative cancer medicines. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.
Long Name BeOne Medicines AG
Market us_market
Market Cap 40,170,516,480
Market State REGULAR
Max Age 86,400
Message Board Id finmb_115205344
Most Recent Quarter 1,782,777,600
Name Change Date 2,026-10-14
Net Income To Common 655,707,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 42,287,435,420
Number Of Analyst Opinions 27
Open 346.05
Operating Cashflow 1,484,056,064
Operating Margins 0.19063999
Payout Ratio 0.0
Peg Ratio 0.74
Phone 41 61 685 19 00
Prev Name BeiGene, Ltd.
Previous Close 349.08
Price Eps Current Year 46.20726
Price Hint 2
Price To Book 7.712925
Price To Sales Trailing12 Months 6.5542107
Profit Margins 0.106979996
Quick Ratio 2.911
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.33333
Region US
Regular Market Change 4.01001
Regular Market Change Percent 1.1480788
Regular Market Day High 354.39
Regular Market Day Low 345.84
Regular Market Day Range 345.84 - 354.39
Regular Market Open 346.05
Regular Market Previous Close 349.08
Regular Market Price 353.09
Regular Market Time 1,791,992,023
Regular Market Volume 61,499
Return On Assets 0.07457
Return On Equity 0.14661999
Revenue Growth 0.296
Revenue Per Share 55.275
Sand P52 Week Change 0.17004645
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 104,918,094
Shares Percent Shares Out 0.017
Shares Short 1,933,092
Shares Short Previous Month Date 1,788,134,400
Shares Short Prior Month 1,422,559
Short Name BeOne Medicines Ltd.
Short Percent Of Float 0.0239
Short Ratio 4.96
Source Interval 15
Symbol ONC
Target High Price 528.0
Target Low Price 370.0
Target Mean Price 435.53445
Target Median Price 439.41
Total Cash 5,098,040,832
Total Cash Per Share 44.837
Total Debt 2,049,524,992
Total Revenue 6,128,963,072
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps 5.59
Trailing P E 63.164577
Trailing Peg Ratio 0.7722
Triggerable 1
Two Hundred Day Average 321.70453
Two Hundred Day Average Change 31.385468
Two Hundred Day Average Change Percent 0.09755992
Type Disp Equity
Volume 61,499
Website https://beonemedicines.com
Zip 4,051