Olema Pharmaceuticals, Inc. (OLMA)Healthcare | Biotechnology | San Francisco, United States | NasdaqGS
16.58 USD
-0.24
(-1.427%) ⇩
(April 20, 2026, 4 p.m.
EDT)
Short-term: ★★★★☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆ |
Hot Take | April 19, 2026, 12:23 a.m. EDT
Olema is trading at a technical inflection point where risk-averse capital has established a $25 mask via heavy call OI, while the recent 33% downward trend likely has reached over-extended territory. The skewed options distribution for May 2026 implies an asymmetric bet on upside movement to test resistance, despite the stock remaining in bear territory (R=1) due to negative earnings and lack of dividend history. |
| Model | MAE |
|---|---|
| MSTL ✓ | 0.298626 |
| AutoTheta | 0.321398 |
| AutoETS | 0.321749 |
| AutoARIMA | 0.336548 |
Forecast horizon: 45 days | Selected: MSTL
| Forecast Reliability | |
|---|---|
| Score | 41% |
| H-stat | 69.37 |
| Ljung-Box p | 0.000 |
| Jarque-Bera p | 0.050 |
| Excess Kurtosis | -1.78 |
| Attribute | Value |
|---|---|
| Sector | Healthcare |
| Debt to Equity Ratio | 0.876 |
| Market Cap | 1,445,062,400 |
| Forward P/E | -6.52 |
| Beta | 2.18 |
| Website | https://olema.com |
As of April 19, 2026, 12:23 a.m. EDT: Options activity shows a clear bullish bias for the near term. The May 2026 call chain has massive Open Interest (OI) at 30.0 ($3.6k) and 25.0 ($136) strikes, suggesting a price ceiling expectation between $25-$30. Conversely, put volume and OI are heavily concentrated below $17, with significant protection buying at 14.0 and below in the July 2026 table. This structure indicates speculators are positioning for a rebound from current levels ($16.82), betting on the 30.0 strike being the primary resistance, while selling deep out-of-the-money puts to support a potential upside move.
| Attribute | Value |
|---|---|
| 52 Week Change | 2.342742 |
| Address1 | 780 Brannan Street |
| All Time High | 60.27 |
| All Time Low | 2.0 |
| Ask | 16.65 |
| Ask Size | 1 |
| Audit Risk | 5 |
| Average Daily Volume10 Day | 868,810 |
| Average Daily Volume3 Month | 1,600,600 |
| Average Volume | 1,600,600 |
| Average Volume10Days | 868,810 |
| Beta | 2.182 |
| Bid | 16.5 |
| Bid Size | 1 |
| Board Risk | 8 |
| Book Value | 5.881 |
| City | San Francisco |
| Compensation As Of Epoch Date | 1,735,603,200 |
| Compensation Risk | 10 |
| Country | United States |
| Crypto Tradeable | 0 |
| Currency | USD |
| Current Price | 16.58 |
| Current Ratio | 9.95 |
| Custom Price Alert Confidence | HIGH |
| Date Short Interest | 1,774,915,200 |
| Day High | 17.465 |
| Day Low | 16.31 |
| Debt To Equity | 0.876 |
| Display Name | Olema Pharmaceuticals |
| Earnings Timestamp | 1,773,664,200 |
| Earnings Timestamp End | 1,778,589,000 |
| Earnings Timestamp Start | 1,778,589,000 |
| Ebitda | -168,208,000 |
| Ebitda Margins | 0.0 |
| Enterprise To Ebitda | -5.611 |
| Enterprise Value | 943,818,432 |
| Eps Current Year | -2.28745 |
| Eps Forward | -2.5439 |
| Eps Trailing Twelve Months | -1.87 |
| Esg Populated | 0 |
| Exchange | NMS |
| Exchange Data Delayed By | 0 |
| Exchange Timezone Name | America/New_York |
| Exchange Timezone Short Name | EDT |
| Fifty Day Average | 18.646 |
| Fifty Day Average Change | -2.066 |
| Fifty Day Average Change Percent | -0.11080124 |
| Fifty Two Week Change Percent | 234.2742 |
| Fifty Two Week High | 36.259 |
| Fifty Two Week High Change | -19.678999 |
| Fifty Two Week High Change Percent | -0.5427342 |
| Fifty Two Week Low | 3.89 |
| Fifty Two Week Low Change | 12.69 |
| Fifty Two Week Low Change Percent | 3.2622106 |
| Fifty Two Week Range | 3.89 - 36.259 |
| Financial Currency | USD |
| First Trade Date Milliseconds | 1,605,796,200,000 |
| Float Shares | 67,426,368 |
| Forward Eps | -2.5439 |
| Forward P E | -6.517552 |
| Free Cashflow | -82,896,248 |
| Full Exchange Name | NasdaqGS |
| Full Time Employees | 131 |
| Gmt Off Set Milliseconds | -14,400,000 |
| Governance Epoch Date | 1,775,001,600 |
| Gross Margins | 0.0 |
| Has Pre Post Market Data | 1 |
| Held Percent Insiders | 0.01972 |
| Held Percent Institutions | 1.01128 |
| Implied Shares Outstanding | 87,156,961 |
| Industry | Biotechnology |
| Industry Disp | Biotechnology |
| Industry Key | biotechnology |
| Ipo Expected Date | 2,020-11-19 |
| Is Earnings Date Estimate | 1 |
| Language | en-US |
| Last Fiscal Year End | 1,767,139,200 |
| Long Business Summary | Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. The company's lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic ER-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, a mechanistic target of rapamycin inhibitor, and a CDK4 inhibitor that is in Phase 1b/2 clinical trial for the treatment of ER+/HER2- advanced or metastatic breast cancer. It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 which is in Phase 1 clinical trials for patients with breast and other solid tumor cancers. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009. Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California. |
| Long Name | Olema Pharmaceuticals, Inc. |
| Market | us_market |
| Market Cap | 1,445,062,400 |
| Market State | PRE |
| Max Age | 86,400 |
| Message Board Id | finmb_540573682 |
| Most Recent Quarter | 1,767,139,200 |
| Net Income To Common | -162,451,008 |
| Next Fiscal Year End | 1,798,675,200 |
| Non Diluted Market Cap | 1,445,062,413 |
| Number Of Analyst Opinions | 11 |
| Open | 16.79 |
| Operating Cashflow | -146,716,000 |
| Operating Margins | 0.0 |
| Overall Risk | 9 |
| Payout Ratio | 0.0 |
| Phone | 415 651 3316 |
| Pre Market Change | 0.049999237 |
| Pre Market Change Percent | 0.30156356 |
| Pre Market Price | 16.63 |
| Pre Market Time | 1,776,769,083 |
| Previous Close | 16.82 |
| Price Eps Current Year | -7.2482457 |
| Price Hint | 2 |
| Price To Book | 2.8192484 |
| Profit Margins | 0.0 |
| Quick Ratio | 9.835 |
| Quote Source Name | Nasdaq Real Time Price |
| Quote Type | EQUITY |
| Recommendation Key | none |
| Region | US |
| Regular Market Change | -0.24 |
| Regular Market Change Percent | -1.42687 |
| Regular Market Day High | 17.465 |
| Regular Market Day Low | 16.31 |
| Regular Market Day Range | 16.31 - 17.465 |
| Regular Market Open | 16.79 |
| Regular Market Previous Close | 16.82 |
| Regular Market Price | 16.58 |
| Regular Market Time | 1,776,715,200 |
| Regular Market Volume | 1,142,669 |
| Return On Assets | -0.21420999 |
| Return On Equity | -0.36608002 |
| Sand P52 Week Change | 0.34445214 |
| Sector | Healthcare |
| Sector Disp | Healthcare |
| Sector Key | healthcare |
| Share Holder Rights Risk | 8 |
| Shares Outstanding | 87,156,961 |
| Shares Percent Shares Out | 0.1407 |
| Shares Short | 12,265,390 |
| Shares Short Previous Month Date | 1,772,150,400 |
| Shares Short Prior Month | 8,257,215 |
| Short Name | Olema Pharmaceuticals, Inc. |
| Short Percent Of Float | 0.1516 |
| Short Ratio | 5.19 |
| Source Interval | 15 |
| State | CA |
| Symbol | OLMA |
| Target High Price | 62.0 |
| Target Low Price | 27.0 |
| Target Mean Price | 43.0 |
| Target Median Price | 40.0 |
| Total Cash | 505,436,992 |
| Total Cash Per Share | 5.799 |
| Total Debt | 4,193,000 |
| Tradeable | 0 |
| Trailing Annual Dividend Rate | 0.0 |
| Trailing Annual Dividend Yield | 0.0 |
| Trailing Eps | -1.87 |
| Trailing Peg Ratio | None |
| Triggerable | 1 |
| Two Hundred Day Average | 15.39885 |
| Two Hundred Day Average Change | 1.1811495 |
| Two Hundred Day Average Change Percent | 0.07670374 |
| Type Disp | Equity |
| Volume | 1,142,669 |
| Website | https://olema.com |
| Zip | 94,103 |