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OnKure Therapeutics, Inc. (OKUR)

Healthcare | Biotechnology | Boulder, United States | NasdaqGM
5.00 USD +0.33 (7.066%) ⇧ (April 17, 2026, 4 p.m. EDT)
After hours: 4.90 -0.10 (-0.100%) ⇩ (April 17, 2026, 7:34 p.m. EDT)

Short-term: ★☆☆☆☆ | Long-term: ★☆☆☆☆ | Dividends: ☆☆☆☆☆
Hot Take | April 19, 2026, midnight EDT

Despite massive positive catalysts like a $150M private placement and strong analyst consensus, the negative short-term momentum prediction combined with the company's deep burn rate and lack of dividends suggests a high-risk, high-reward scenario where immediate protection is difficult. Long-term upside remains significant if clinical milestones are hit, but valuations are stretched given the -4.71 EPS and negative cash flow.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.234392
MSTL0.242153
AutoETS0.243790
AutoTheta0.244356

Forecast horizon: 45 days | Selected: AutoARIMA

Forecast Reliability
Score 48%
H-stat 4.90
Ljung-Box p 0.000
Jarque-Bera p 0.087
Excess Kurtosis -1.60
Attribute Value
Sector Healthcare
Debt to Equity Ratio 0.977
Market Cap 68,367,824
Forward P/E -2.43
Website https://onkuretherapeutics.com

Info Dump

Attribute Value
52 Week Change 0.83150184
Address1 6,707 Winchester Circle
Address2 Suite 400
All Time High 171.8
All Time Low 1.7
Ask 5.07
Ask Size 2
Average Analyst Rating 1.0 - Strong Buy
Average Daily Volume10 Day 185,000
Average Daily Volume3 Month 288,675
Average Volume 288,675
Average Volume10Days 185,000
Bid 4.95
Bid Size 2
Book Value 4.109
City Boulder
Compensation As Of Epoch Date 1,767,139,200
Country United States
Crypto Tradeable 0
Currency USD
Current Price 5.0
Current Ratio 10.275
Custom Price Alert Confidence HIGH
Date Short Interest 1,774,915,200
Day High 5.06
Day Low 4.67
Debt To Equity 0.977
Display Name OnKure Therapeutics
Earnings Timestamp End 1,755,261,000
Earnings Timestamp Start 1,754,915,400
Ebitda -62,503,000
Ebitda Margins 0.0
Enterprise To Ebitda -0.158
Enterprise Value 9,866,825
Eps Current Year -2.655
Eps Forward -2.05667
Eps Trailing Twelve Months -4.4
Esg Populated 0
Exchange NGM
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 3.5095
Fifty Day Average Change 1.4905
Fifty Day Average Change Percent 0.42470437
Fifty Two Week Change Percent 83.150185
Fifty Two Week High 5.06
Fifty Two Week High Change -0.059999943
Fifty Two Week High Change Percent -0.011857696
Fifty Two Week Low 1.7
Fifty Two Week Low Change 3.3
Fifty Two Week Low Change Percent 1.9411764
Fifty Two Week Range 1.7 - 5.06
Financial Currency USD
First Trade Date Milliseconds 1,617,888,600,000
Float Shares 5,256,802
Forward Eps -2.05667
Forward P E -2.4311144
Free Cashflow -31,100,750
Full Exchange Name NasdaqGM
Full Time Employees 45
Gmt Off Set Milliseconds -14,400,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.01705
Held Percent Institutions 1.46509
Implied Shares Outstanding 13,673,565
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Last Split Date 1,728,259,200
Last Split Factor 1:10
Long Business Summary OnKure Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers and other diseases. Its lead product candidate includes OKI-219, a selective inhibitor of phosphoinositide 3-kinase alpha (PI3Ka) harboring the H1047R mutation that is in Phase 1 clinical trial for the treatment of solid tumors, including breast cancer. The company was founded in 2011 and is headquartered in Boulder, Colorado.
Long Name OnKure Therapeutics, Inc.
Market us_market
Market Cap 68,367,824
Market State CLOSED
Max Age 86,400
Message Board Id finmb_142375117
Most Recent Quarter 1,767,139,200
Net Income To Common -59,517,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 71,800,460
Number Of Analyst Opinions 5
Open 4.77
Operating Cashflow -51,828,000
Operating Margins 0.0
Payout Ratio 0.0
Phone 720-307-2892
Post Market Change -0.099999905
Post Market Change Percent -1.9999981
Post Market Price 4.9
Post Market Time 1,776,468,868
Previous Close 4.67
Price Eps Current Year -1.8832392
Price Hint 4
Price To Book 1.216841
Profit Margins 0.0
Quick Ratio 9.973
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.0
Region US
Regular Market Change 0.33
Regular Market Change Percent 7.06638
Regular Market Day High 5.06
Regular Market Day Low 4.67
Regular Market Day Range 4.67 - 5.06
Regular Market Open 4.77
Regular Market Previous Close 4.67
Regular Market Price 5.0
Regular Market Time 1,776,456,000
Regular Market Volume 299,095
Return On Assets -0.4445
Return On Equity -0.74391
Sand P52 Week Change 0.38150132
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Shares Outstanding 13,673,565
Shares Percent Shares Out 0.012
Shares Short 163,904
Shares Short Previous Month Date 1,772,150,400
Shares Short Prior Month 53,751
Short Name OnKure Therapeutics, Inc.
Short Percent Of Float 0.0153
Short Ratio 0.29
Source Interval 15
State CO
Symbol OKUR
Target High Price 30.0
Target Low Price 11.0
Target Mean Price 20.2
Target Median Price 17.0
Total Cash 59,050,000
Total Cash Per Share 4.319
Total Debt 549,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -4.4
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 2.94605
Two Hundred Day Average Change 2.05395
Two Hundred Day Average Change Percent 0.6971878
Type Disp Equity
Volume 299,095
Website https://onkuretherapeutics.com
Zip 80,301