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Nuvalent, Inc. (NUVL)

Healthcare | Biotechnology | Cambridge, United States | NasdaqGS
123.94 USD +0.04 (0.032%) ⇧ (July 13, 2026, 4 p.m. EDT)

Short-term:★★★⯪☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:58 a.m. EDT

Nuvalent is trading at the precipice of a GSK acquisition, priced just shy of the reported $124 cash offer. While the stock has rallied nearly fourfold over the last three years, the underlying financials tell a different story: negative earnings, negative free cash flow, and a return on equity of negative forty-one percent. The recent price surge is clearly driven by the buyout rumor rather than operational improvement. Options flow shows aggressive call buying targeting prices above the buyout threshold, but the elevated put implied volatility suggests investors are wary of deal failure. For a long-term investor, the negative fundamentals and high risk profile warrant caution; the current valuation is entirely dependent on the transaction completion. Short-term traders may find momentum here, but the lack of organic growth makes this a speculative play on M&A rather than a fundamental investment.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.067369
AutoETS0.068140
AutoARIMA0.068232
MSTL0.069514

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 36%
H-stat 22.80
Ljung-Box p 0.000
Jarque-Bera p 0.691
Excess Kurtosis -0.42
Attribute Value
Sector Healthcare
Market Cap 9,791,001,600
Forward P/E -30.00
Beta 1.14
Website https://nuvalent.com

As of July 11, 2026, 2:58 a.m. EDT: Call volume is heavily skewed toward out-of-the-money strikes, with ninety-six percent of open interest in OTM positions for the nearest expiration, indicating bullish speculation on a price move above current levels. Notable new flow appears at the 120 and 130 strikes. However, implied volatility for puts is significantly higher than calls in the near term, suggesting investors are hedging against downside risk or anticipating deal uncertainty.


Info Dump

Attribute Value
52 Week Change 0.46471214
Address1 One Broadway
Address2 14th Floor
All Time High 123.91
All Time Low 7.09
Ask 123.96
Ask Size 1
Audit Risk 6
Average Daily Volume10 Day 1,660,580
Average Daily Volume3 Month 2,264,562
Average Volume 2,264,562
Average Volume10Days 1,660,580
Beta 1.138
Bid 123.94
Bid Size 5
Board Risk 4
Book Value 14.888
City Cambridge
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 7
Country United States
Crypto Tradeable 0
Currency USD
Current Price 123.94
Current Ratio 16.137
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 123.97
Day Low 123.87
Display Name Nuvalent
Earnings Timestamp 1,778,157,000
Earnings Timestamp End 1,786,019,400
Earnings Timestamp Start 1,786,019,400
Ebitda Margins 0.0
Enterprise Value 8,503,525,376
Eps Current Year -5.47538
Eps Forward -4.13175
Eps Trailing Twelve Months -6.06
Esg Populated 0
Exchange NMS
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 110.7544
Fifty Day Average Change 13.1856
Fifty Day Average Change Percent 0.119052604
Fifty Two Week Change Percent 46.471214
Fifty Two Week High 123.97
Fifty Two Week High Change -0.02999878
Fifty Two Week High Change Percent -0.00024198418
Fifty Two Week Low 71.13
Fifty Two Week Low Change 52.810005
Fifty Two Week Low Change Percent 0.7424435
Fifty Two Week Range 71.13 - 123.97
Financial Currency USD
First Trade Date Milliseconds 1,627,565,400,000
Float Shares 49,108,264
Forward Eps -4.13175
Forward P E -29.996975
Free Cashflow -180,427,744
Full Exchange Name NasdaqGS
Full Time Employees 234
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.0
Has Pre Post Market Data 1
Held Percent Insiders 0.02781
Held Percent Institutions 1.1327
Implied Shares Outstanding 78,997,915
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Ipo Expected Date 2,021-07-29
Is Earnings Date Estimate 1
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are Zidesamtinib (NVL-520), a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the Phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; Neladalkib (NVL-655), a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the Phase 2 portion of the ALKOVE-1 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR that is in Phase 1a/1b clinical trial. Nuvalent, Inc. has a strategic partnership with Guardant Health, Inc. to develop companion diagnostics therapies. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.
Long Name Nuvalent, Inc.
Market us_market
Market Cap 9,791,001,600
Market State PRE
Max Age 86,400
Message Board Id finmb_702442629
Most Recent Quarter 1,774,915,200
Net Income To Common -450,073,984
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 9,807,154,188
Number Of Analyst Opinions 16
Open 123.88
Operating Cashflow -312,787,008
Operating Margins 0.0
Overall Risk 8
Payout Ratio 0.0
Phone 857 357 7000
Previous Close 123.9
Price Eps Current Year -22.635872
Price Hint 2
Price To Book 8.324826
Profit Margins 0.0
Quick Ratio 15.885
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key none
Region US
Regular Market Change 0.0400009
Regular Market Change Percent 0.0322848
Regular Market Day High 123.97
Regular Market Day Low 123.87
Regular Market Day Range 123.87 - 123.97
Regular Market Open 123.88
Regular Market Previous Close 123.9
Regular Market Price 123.94
Regular Market Time 1,783,972,800
Regular Market Volume 2,456,744
Return On Assets -0.22513
Return On Equity -0.41189
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 73,562,661
Shares Percent Shares Out 0.0368
Shares Short 2,908,403
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 5,241,004
Short Name Nuvalent, Inc.
Short Percent Of Float 0.0617
Short Ratio 0.56
Source Interval 15
State MA
Symbol NUVL
Target High Price 140.0
Target Low Price 124.0
Target Mean Price 125.125
Target Median Price 124.0
Total Cash 1,287,475,968
Total Cash Per Share 16.298
Total Debt 0
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -6.06
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 102.76408
Two Hundred Day Average Change 21.175926
Two Hundred Day Average Change Percent 0.20606351
Type Disp Equity
Volume 2,456,744
Website https://nuvalent.com
Zip 2,142