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Nuvation Bio Inc. (NUVB)

Healthcare | Biotechnology | New York, United States | NYSE
6.66 USD -0.33 (-4.721%) ⇩ (Aug. 28, 2026, 4 p.m. EDT)
After hours: 6.65 -0.01 (-0.010%) ⇩ (Aug. 28, 2026, 7:52 p.m. EDT)

Short-term:★★⯪☆☆Long-term:★★⯪☆☆Dividends:☆☆☆☆☆
Hot Take | Aug. 22, 2026, 1:33 a.m. EDT

The investment case for Nuvation Bio is currently paralyzed by a stark contradiction between its operational reality and its speculative pricing. Fundamentally, the company is a classic biotech value trap: it is burning cash aggressively with negative operating margins, trading at a negative forward P/E, and showing no path to profitability in the visible future. The balance sheet, while bolstered by recent convertible note offerings, is not a fortress against the inevitable dilution required to fund these clinical trials. Consequently, the long-term rating remains neutral; the market has priced in a high probability of failure or further dilution, making the current valuation a reflection of risk rather than a margin of safety. However, the short-term outlook is driven entirely by binary event risk. The stock is hovering near the $5.00 strike price, which acts as a psychological and technical floor supported by heavy option open interest. This creates a volatile environment where the stock can rally on positive clinical data or financing news, only to crash back down if results are merely 'mixed.' The recent price action shows resilience, trading above the 50-day average, but this is likely a reaction to the capital raise rather than a reversal of the multi-year downtrend. Without a confirmed catalyst that moves the needle on the pipeline, the stock lacks the fundamental momentum to sustain a higher valuation. Investors here are essentially buying lottery tickets on a company that is actively managing its own survival through equity issuance.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoTheta ✓0.152198
AutoARIMA0.177251
AutoETS0.177251
MSTL0.188781

Forecast horizon: 45 days | Selected: AutoTheta

Forecast Reliability
Score 31%
H-stat 11.92
Ljung-Box p 0.000
Jarque-Bera p 0.327
Excess Kurtosis -0.92
Attribute Value
Sector Healthcare
Debt to Equity Ratio 163.971
Revenue per Share 0.497
Market Cap 2,338,480,640
Forward P/E -444.00
Beta 1.53
Profit Margins -88.19%
Website https://www.nuvationbio.com

As of Aug. 22, 2026, 1:33 a.m. EDT: Speculators are positioning for significant volatility rather than a clear directional move. Call Open Interest is heavily concentrated at the $5.00 strike across near-term expirations, acting as a major support wall, while Put Open Interest dominates at lower strikes ($2.50-$5.00) for longer-dated contracts, suggesting a 'long gamma' environment where the market expects a range-bound bounce between $2.50 and $7.50. The massive volume spike in December puts indicates fear of a deeper decline, yet the ATM skew remains relatively balanced, implying uncertainty rather than a definitive bearish thesis.


Info Dump

Attribute Value
52 Week Change 1.3694916
Address1 1,500 Broadway
Address2 Suite 1401
All Time High 15.23
All Time Low 0.95
Ask 6.66
Ask Size 5,000
Audit Risk 5
Average Analyst Rating 1.5 - Strong Buy
Average Daily Volume10 Day 6,241,220
Average Daily Volume3 Month 6,857,190
Average Volume 6,857,190
Average Volume10Days 6,241,220
Beta 1.525
Bid 6.66
Bid Size 5,100
Board Risk 8
Book Value 0.726
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 6.66
Current Ratio 8.373
Custom Price Alert Confidence HIGH
Date Short Interest 1,786,665,600
Day High 6.9956
Day Low 6.625
Debt To Equity 163.971
Display Name Nuvation Bio
Earnings Call Timestamp End 1,786,017,600
Earnings Call Timestamp Start 1,786,017,600
Earnings Timestamp 1,786,019,400
Earnings Timestamp End 1,793,622,600
Earnings Timestamp Start 1,793,622,600
Ebitda -135,480,992
Ebitda Margins -0.79741997
Enterprise To Ebitda -15.454
Enterprise To Revenue 12.324
Enterprise Value 2,093,787,776
Eps Current Year -0.29
Eps Forward -0.015
Eps Trailing Twelve Months -0.42
Esg Populated 0
Exchange NYQ
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 6.2374
Fifty Day Average Change 0.4225998
Fifty Day Average Change Percent 0.067752555
Fifty Two Week Change Percent 136.94916
Fifty Two Week High 9.75
Fifty Two Week High Change -3.0900002
Fifty Two Week High Change Percent -0.31692308
Fifty Two Week Low 2.91
Fifty Two Week Low Change 3.7499998
Fifty Two Week Low Change Percent 1.2886597
Fifty Two Week Range 2.91 - 9.75
Financial Currency USD
First Trade Date Milliseconds 1,598,448,600,000
Float Shares 263,647,902
Forward Eps -0.015
Forward P E -444.0
Free Cashflow -112,112,496
Full Exchange Name NYSE
Full Time Employees 305
Fullday Change -0.33
Fullday Change Percent -4.72103
Fullday Price 6.65
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,785,542,400
Gross Margins 0.88175005
Gross Profits 149,810,000
Has Pre Post Market Data 1
Held Percent Insiders 0.18444
Held Percent Institutions 0.67926
Implied Shares Outstanding 351,123,233
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.
Long Name Nuvation Bio Inc.
Market us_market
Market Cap 2,338,480,640
Market State CLOSED
Max Age 86,400
Message Board Id finmb_639036735
Most Recent Quarter 1,782,777,600
Net Income To Common -149,827,008
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,454,351,398
Number Of Analyst Opinions 10
Open 6.9
Operating Cashflow -120,522,000
Operating Margins -1.61063
Overall Risk 10
Payout Ratio 0.0
Phone 332 208 6102
Post Market Change -0.009999752
Post Market Change Percent -0.15014642
Post Market Price 6.65
Post Market Time 1,787,961,165
Previous Close 6.99
Price Eps Current Year -22.965517
Price Hint 2
Price To Book 9.173553
Price To Sales Trailing12 Months 13.7638645
Profit Margins -0.88185
Quick Ratio 7.984
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.45455
Region US
Regular Market Change -0.33
Regular Market Change Percent -4.72103
Regular Market Day High 6.9956
Regular Market Day Low 6.625
Regular Market Day Range 6.625 - 6.9956
Regular Market Open 6.9
Regular Market Previous Close 6.99
Regular Market Price 6.66
Regular Market Time 1,787,947,202
Regular Market Volume 3,660,705
Return On Assets -0.12361
Return On Equity -0.47809
Revenue Growth 5.556
Revenue Per Share 0.497
Sand P52 Week Change 0.20504117
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 350,123,233
Shares Percent Shares Out 0.1516
Shares Short 53,222,212
Shares Short Previous Month Date 1,784,073,600
Shares Short Prior Month 55,668,014
Short Name Nuvation Bio Inc.
Short Percent Of Float 0.2496
Short Ratio 8.78
Source Interval 15
State NY
Symbol NUVB
Target High Price 21.0
Target Low Price 7.0
Target Mean Price 13.1
Target Median Price 12.5
Total Cash 660,956,032
Total Cash Per Share 1.882
Total Debt 416,263,008
Total Revenue 169,900,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.42
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 5.8973
Two Hundred Day Average Change 0.7627001
Two Hundred Day Average Change Percent 0.1293304
Type Disp Equity
Volume 3,660,705
Website https://www.nuvationbio.com
Zip 10,036