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Nuvation Bio Inc. (NUVB)

Healthcare | Biotechnology | New York, United States | NYSE
5.77 USD -0.04 (-0.688%) ⇩ (July 13, 2026, 4 p.m. EDT)
After hours: 5.78 +0.01 (0.147%) ⇧ (July 13, 2026, 7:59 p.m. EDT)

Short-term:★★☆☆☆Long-term:★☆☆☆☆Dividends:☆☆☆☆☆
Hot Take | July 11, 2026, 2:52 a.m. EDT

The long-term investment case is severely compromised by a brutal multi-year decline; the stock has lost over three-quarters of its value since 2021, with the most recent annual return being negative. While the company boasts impressive gross margins and a massive cash pile relative to debt, the relentless price erosion suggests the market views the current valuation as unjustified given the execution risks inherent in biotech development. The short-term outlook remains fragile; despite a recent bounce off the lows, the options market is screaming for downside protection, with traders buying deep out-of-the-money puts to guard against further collapse. The statistical forecast offers no directional clarity, leaving the trade entirely dependent on whether the company can prove its pipeline can deliver results soon enough to reverse the structural damage done to the share price.

Model Selection — Backtest MAE (log-scale, lower is better)
ModelMAE
AutoARIMA ✓0.076284
AutoETS0.076284
MSTL0.077726
AutoTheta0.078075
MSTL_1150.096859
MSTL_840.125990
MSTL_84_1150.133450

Forecast horizon: 60 days | Selected: AutoARIMA

Forecast Reliability
Score 31%
H-stat 8.94
Ljung-Box p 0.000
Jarque-Bera p 0.193
Excess Kurtosis -0.38
Attribute Value
Sector Healthcare
Debt to Equity Ratio 67.9
Revenue per Share 0.416
Market Cap 2,009,125,504
Forward P/E -96.17
Beta 1.53
Profit Margins -102.06%
Website https://www.nuvationbio.com

As of July 11, 2026, 2:52 a.m. EDT: Speculators are heavily positioned for downside protection, with massive open interest in out-of-the-money puts expiring in late 2026 and early 2027. Call activity is concentrated in out-of-the-money strikes, suggesting a speculative hope for a recovery to $7.50, but the sheer volume of put buying indicates a dominant fear of further decline rather than a bullish breakout.


Info Dump

Attribute Value
52 Week Change 1.7149532
Address1 1,500 Broadway
Address2 Suite 1401
All Time High 15.23
All Time Low 0.95
Ask 5.78
Ask Size 3,300
Audit Risk 5
Average Analyst Rating 1.4 - Strong Buy
Average Daily Volume10 Day 11,325,790
Average Daily Volume3 Month 5,957,563
Average Volume 5,957,563
Average Volume10Days 11,325,790
Beta 1.527
Bid 5.58
Bid Size 6,700
Board Risk 8
Book Value 0.919
City New York
Compensation As Of Epoch Date 1,767,139,200
Compensation Risk 9
Country United States
Crypto Tradeable 0
Currency USD
Current Price 5.77
Current Ratio 7.439
Custom Price Alert Confidence HIGH
Date Short Interest 1,782,777,600
Day High 5.79
Day Low 5.565
Debt To Equity 67.9
Display Name Nuvation Bio
Earnings Call Timestamp End 1,777,926,600
Earnings Call Timestamp Start 1,777,926,600
Earnings Timestamp 1,777,924,800
Earnings Timestamp End 1,777,924,800
Earnings Timestamp Start 1,777,924,800
Ebitda -148,214,000
Ebitda Margins -1.03613
Enterprise To Ebitda -11.418
Enterprise To Revenue 11.831
Enterprise Value 1,692,380,416
Eps Current Year -0.28
Eps Forward -0.06
Eps Trailing Twelve Months -0.43
Esg Populated 0
Exchange NYQ
Exchange Data Delayed By 0
Exchange Timezone Name America/New_York
Exchange Timezone Short Name EDT
Fifty Day Average 5.0582
Fifty Day Average Change 0.7118001
Fifty Day Average Change Percent 0.14072202
Fifty Two Week Change Percent 171.49532
Fifty Two Week High 9.75
Fifty Two Week High Change -3.98
Fifty Two Week High Change Percent -0.40820512
Fifty Two Week Low 2.06
Fifty Two Week Low Change 3.71
Fifty Two Week Low Change Percent 1.8009709
Fifty Two Week Range 2.06 - 9.75
Financial Currency USD
First Trade Date Milliseconds 1,598,448,600,000
Float Shares 254,657,511
Forward Eps -0.06
Forward P E -96.16667
Free Cashflow -100,037,872
Full Exchange Name NYSE
Full Time Employees 307
Gmt Off Set Milliseconds -14,400,000
Governance Epoch Date 1,782,864,000
Gross Margins 0.90776
Gross Profits 129,851,000
Has Pre Post Market Data 1
Held Percent Insiders 0.18586999
Held Percent Institutions 0.64827
Implied Shares Outstanding 348,201,971
Industry Biotechnology
Industry Disp Biotechnology
Industry Key biotechnology
Is Earnings Date Estimate 0
Language en-US
Last Fiscal Year End 1,767,139,200
Long Business Summary Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York.
Long Name Nuvation Bio Inc.
Market us_market
Market Cap 2,009,125,504
Market State POSTPOST
Max Age 86,400
Message Board Id finmb_639036735
Most Recent Quarter 1,774,915,200
Net Income To Common -145,994,000
Next Fiscal Year End 1,798,675,200
Non Diluted Market Cap 2,023,053,451
Number Of Analyst Opinions 9
Open 5.71
Operating Cashflow -125,731,000
Operating Margins 0.046630003
Overall Risk 10
Payout Ratio 0.0
Phone 332 208 6102
Post Market Change 0.008500099
Post Market Change Percent 0.14731541
Post Market Price 5.7785
Post Market Time 1,783,987,153
Previous Close 5.81
Price Eps Current Year -20.607143
Price Hint 2
Price To Book 6.2785635
Price To Sales Trailing12 Months 14.045311
Profit Margins -1.02061
Quick Ratio 7.038
Quote Source Name Nasdaq Real Time Price
Quote Type EQUITY
Recommendation Key strong_buy
Recommendation Mean 1.4
Region US
Regular Market Change -0.04
Regular Market Change Percent -0.688468
Regular Market Day High 5.79
Regular Market Day Low 5.565
Regular Market Day Range 5.565 - 5.79
Regular Market Open 5.71
Regular Market Previous Close 5.81
Regular Market Price 5.77
Regular Market Time 1,783,972,802
Regular Market Volume 4,593,795
Return On Assets -0.17024
Return On Equity -0.3951
Revenue Growth 25.987
Revenue Per Share 0.416
Sand P52 Week Change 0.20847368
Sector Healthcare
Sector Disp Healthcare
Sector Key healthcare
Share Holder Rights Risk 10
Shares Outstanding 347,201,971
Shares Percent Shares Out 0.15609999
Shares Short 54,363,151
Shares Short Previous Month Date 1,780,012,800
Shares Short Prior Month 53,671,108
Short Name Nuvation Bio Inc.
Short Percent Of Float 0.2585
Short Ratio 6.59
Source Interval 15
State NY
Symbol NUVB
Target High Price 19.0
Target Low Price 7.0
Target Mean Price 12.33333
Target Median Price 12.0
Total Cash 533,728,992
Total Cash Per Share 1.533
Total Debt 216,984,000
Total Revenue 143,046,000
Tradeable 0
Trailing Annual Dividend Rate 0.0
Trailing Annual Dividend Yield 0.0
Trailing Eps -0.43
Trailing Peg Ratio None
Triggerable 1
Two Hundred Day Average 5.49535
Two Hundred Day Average Change 0.2746501
Two Hundred Day Average Change Percent 0.049978636
Type Disp Equity
Volume 4,593,795
Website https://www.nuvationbio.com
Zip 10,036